JP2019515652A5 - - Google Patents
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- JP2019515652A5 JP2019515652A5 JP2018548420A JP2018548420A JP2019515652A5 JP 2019515652 A5 JP2019515652 A5 JP 2019515652A5 JP 2018548420 A JP2018548420 A JP 2018548420A JP 2018548420 A JP2018548420 A JP 2018548420A JP 2019515652 A5 JP2019515652 A5 JP 2019515652A5
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- 108091033319 polynucleotide Proteins 0.000 claims description 66
- 102000040430 polynucleotide Human genes 0.000 claims description 66
- 239000002157 polynucleotide Substances 0.000 claims description 66
- 102100022005 B-lymphocyte antigen CD20 Human genes 0.000 claims description 61
- 101000897405 Homo sapiens B-lymphocyte antigen CD20 Proteins 0.000 claims description 61
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- 101000914489 Homo sapiens B-cell antigen receptor complex-associated protein alpha chain Proteins 0.000 claims description 2
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- 101000761179 Homo sapiens Caspase recruitment domain-containing protein 11 Proteins 0.000 claims description 2
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- 101001057504 Homo sapiens Interferon-stimulated gene 20 kDa protein Proteins 0.000 claims description 2
- 101001055144 Homo sapiens Interleukin-2 receptor subunit alpha Proteins 0.000 claims description 2
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021172976A JP7397840B2 (ja) | 2016-03-18 | 2021-10-22 | Ｃｄ２０免疫療法のための組成物および方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662310541P | 2016-03-18 | 2016-03-18 | |
| US62/310,541 | 2016-03-18 | ||
| US201662320327P | 2016-04-08 | 2016-04-08 | |
| US62/320,327 | 2016-04-08 | ||
| PCT/US2017/023098 WO2017161353A1 (en) | 2016-03-18 | 2017-03-17 | Compositions and methods for cd20 immunotherapy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021172976A Division JP7397840B2 (ja) | 2016-03-18 | 2021-10-22 | Ｃｄ２０免疫療法のための組成物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019515652A JP2019515652A (ja) | 2019-06-13 |
| JP2019515652A5 true JP2019515652A5 (https=) | 2020-04-30 |
| JP7065782B2 JP7065782B2 (ja) | 2022-05-12 |
Family
ID=58448653
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018548420A Active JP7065782B2 (ja) | 2016-03-18 | 2017-03-17 | Ｃｄ２０免疫療法のための組成物および方法 |
| JP2021172976A Active JP7397840B2 (ja) | 2016-03-18 | 2021-10-22 | Ｃｄ２０免疫療法のための組成物および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021172976A Active JP7397840B2 (ja) | 2016-03-18 | 2021-10-22 | Ｃｄ２０免疫療法のための組成物および方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US10875927B2 (https=) |
| EP (2) | EP3939994A3 (https=) |
| JP (2) | JP7065782B2 (https=) |
| KR (2) | KR102499191B1 (https=) |
| CN (1) | CN108884144B (https=) |
| AU (1) | AU2017235657B2 (https=) |
| BR (1) | BR112018067977A8 (https=) |
| CA (1) | CA3015369A1 (https=) |
| DK (1) | DK3430038T3 (https=) |
| ES (1) | ES2893840T3 (https=) |
| IL (1) | IL261316B2 (https=) |
| MX (1) | MX2018010415A (https=) |
| NZ (1) | NZ744913A (https=) |
| WO (1) | WO2017161353A1 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| RU2763795C2 (ru) | 2014-04-23 | 2022-01-11 | Джуно Терапьютикс, Инк. | Способы выделения, культивирования и генетической инженерии популяций клеток иммунной системы для адоптивной терапии |
| CN105985444B (zh) * | 2015-02-05 | 2024-02-13 | 博生吉安科细胞技术有限公司 | 一种嵌合抗原受体、以及快速构建嵌合抗原受体的方法及应用 |
| CN108395482B (zh) | 2017-02-08 | 2021-02-05 | 西比曼生物科技（香港）有限公司 | 一种靶向cd20抗原嵌合抗原受体的构建及其工程化t细胞的活性鉴定 |
| EP3704230B1 (en) | 2017-11-01 | 2024-10-23 | Juno Therapeutics, Inc. | Process for generating therapeutic compositions of engineered cells |
| JP7433230B2 (ja) | 2017-12-08 | 2024-02-19 | ジュノー セラピューティクス インコーポレイテッド | 細胞を培養するための無血清培地配合物およびその使用の方法 |
| WO2019113557A1 (en) | 2017-12-08 | 2019-06-13 | Juno Therapeutics, Inc. | Process for producing a composition of engineered t cells |
| US20230158070A1 (en) * | 2018-01-30 | 2023-05-25 | Cellectis | Combination comprising allogeneic immune cells deficient for an antigen present on both t-cells and pathological cells and therapeutic antibody against said antigen |
| JP2021527409A (ja) | 2018-06-14 | 2021-10-14 | ブルーバード バイオ， インコーポレイテッド | Ｃｄ７９ａキメラ抗原受容体 |
| CN113474450A (zh) | 2018-08-09 | 2021-10-01 | 朱诺治疗学股份有限公司 | 产生工程化细胞的方法以及所述工程化细胞的组合物 |
| CN109293781A (zh) * | 2018-09-12 | 2019-02-01 | 中国人民解放军总医院 | 嵌合抗原受体及其基因和重组表达载体、cd19-cd20双靶向性的t细胞及其应用 |
| US11312963B2 (en) * | 2018-10-18 | 2022-04-26 | Synerk Inc. | Compositions and methods for inhibiting TIGIT gene expression |
| KR102840400B1 (ko) | 2018-12-12 | 2025-08-04 | 카이트 파마 인코포레이티드 | 키메라 항원 수용체 및 car-t 세포 및 사용 방법 |
| JP2022522802A (ja) * | 2019-03-01 | 2022-04-20 | グリットストーン バイオ， インコーポレイテッド | Ｔ細胞受容体の選択 |
| GB201906685D0 (en) * | 2019-05-13 | 2019-06-26 | Ultrahuman Six Ltd | Activatable protein constructs and uses thereof |
| US20220280567A1 (en) * | 2019-06-14 | 2022-09-08 | 2Seventy Bio, Inc. | Compositions and methods for treating cancer |
| WO2021009694A1 (en) * | 2019-07-17 | 2021-01-21 | National University Of Singapore | Functional binders synthesized and secreted by immune cells |
| WO2021087305A1 (en) * | 2019-10-30 | 2021-05-06 | Precision Biosciences, Inc. | Cd20 chimeric antigen receptors and methods of use for immunotherapy |
| CN111944062B (zh) * | 2019-12-09 | 2023-11-07 | 深圳市体内生物医药科技有限公司 | 一种识别Fc片段的嵌合抗原受体及其应用 |
| CA3174575A1 (en) * | 2020-03-02 | 2021-09-10 | The Regents Of The University Of California | Chimeric antigen receptors and related methods and compositions for the treatment of cancer |
| CN113402612A (zh) | 2020-03-17 | 2021-09-17 | 西比曼生物科技（香港）有限公司 | 靶向cd19和cd20的联合嵌合抗原受体及其应用 |
| US20230190780A1 (en) * | 2020-05-15 | 2023-06-22 | Precision Biosciences, Inc. | Methods for immunotherapy |
| WO2021231959A1 (en) * | 2020-05-15 | 2021-11-18 | Precision Biosciences, Inc. | Methods for immunotherapy |
| CN114774364B (zh) * | 2022-04-26 | 2024-04-26 | 深圳市体内生物医药科技有限公司 | 一种嵌合抗原受体t细胞及其制备方法和应用 |
| WO2024097315A2 (en) * | 2022-11-02 | 2024-05-10 | Sana Biotechnology, Inc. | Cell therapy products and methods for producing same |
| CA3278900A1 (en) | 2023-03-31 | 2024-10-03 | AbelZeta Inc. | BISPECIFIC CHIMERIC ANTIGENIC RECEPTORS TARGETING CD20 AND BCMA |
| WO2026006767A1 (en) | 2024-06-28 | 2026-01-02 | Dispatch Biotherapeutics, Inc. | Tethered il-9/il-9r and related engineered cells and methods |
| WO2026073918A1 (en) * | 2024-10-02 | 2026-04-09 | Galapagos Nv | Novel anti-cd20 binding domains and uses thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US5283173A (en) | 1990-01-24 | 1994-02-01 | The Research Foundation Of State University Of New York | System to detect protein-protein interactions |
| US5827642A (en) | 1994-08-31 | 1998-10-27 | Fred Hutchinson Cancer Research Center | Rapid expansion method ("REM") for in vitro propagation of T lymphocytes |
| US6759243B2 (en) | 1998-01-20 | 2004-07-06 | Board Of Trustees Of The University Of Illinois | High affinity TCR proteins and methods |
| WO2000023573A2 (en) * | 1998-10-20 | 2000-04-27 | City Of Hope | Cd20-specific redirected t cells and their use in cellular immunotherapy of cd20+ malignancies |
| US7070995B2 (en) | 2001-04-11 | 2006-07-04 | City Of Hope | CE7-specific redirected immune cells |
| US7514537B2 (en) | 2001-04-30 | 2009-04-07 | City Of Hope | Chimeric immunoreceptor useful in treating human gliomas |
| KR20080031001A (ko) * | 2005-06-02 | 2008-04-07 | 아스트라제네카 아베 | Ｃｄ20에 대한 항체 및 그의 용도 |
| WO2008042814A2 (en) | 2006-09-29 | 2008-04-10 | California Institute Of Technology | Mart-1 t cell receptors |
| EP2231183A2 (en) | 2007-12-21 | 2010-09-29 | Genentech, Inc. | Therapy of rituximab-refractory rheumatoid arthritis patients |
| KR101319499B1 (ko) | 2008-02-22 | 2013-10-17 | 엘지디스플레이 주식회사 | 화학적 자기조립 방법을 이용한 나노선 혹은탄소나노튜브의 적층 및 패턴형성 방법과, 이를 적용한액정표시장치의 제조방법 |
| EP4032552B1 (en) | 2008-08-26 | 2023-10-04 | City of Hope | Method and compositions for enhanced anti-tumor effector functioning of t cells |
| DK2496698T3 (en) | 2009-11-03 | 2019-04-15 | Hope City | TRUNCATED EPIDERIMAL GROWTH FACTOR RECEPTOR (EGFRt) FOR TRUNCATED T-CELL SELECTION |
| PH12013501201A1 (en) | 2010-12-09 | 2013-07-29 | Univ Pennsylvania | Use of chimeric antigen receptor-modified t cells to treat cancer |
| CN110200997A (zh) * | 2011-03-23 | 2019-09-06 | 弗雷德哈钦森癌症研究中心 | 用于细胞免疫治疗的方法和组合物 |
| KR101992502B1 (ko) | 2011-05-12 | 2019-06-24 | 제넨테크, 인크. | 프레임워크 시그너처 펩티드를 사용하여 동물 샘플에서 치료 항체를 검출하기 위한 다중 반응 모니터링 lc-ms/ms 방법 |
| US20140004037A1 (en) | 2012-01-19 | 2014-01-02 | Therapeutic Proteins, Inc. | Stabilization of the anti-cd20 antibody rituximab |
| CA2881981A1 (en) | 2012-08-20 | 2014-02-27 | Fred Hutchinson Cancer Research Center | Method and compositions for cellular immunotherapy |
| SG11201503393SA (en) | 2012-11-02 | 2015-06-29 | Tg Therapeutics Inc | Combination of anti-cd20 antibody and pi3 kinase selective inhibitor |
| UY35468A (es) | 2013-03-16 | 2014-10-31 | Novartis Ag | Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19 |
| CN105143269B (zh) * | 2013-09-25 | 2020-05-22 | 北京安保康生物医药科技有限公司 | 抗cd20的全人源单克隆抗体及其应用 |
| CN113354744A (zh) | 2013-12-20 | 2021-09-07 | 弗雷德哈钦森癌症研究中心 | 带标签的嵌合效应分子及其受体 |
| SG10201913765YA (en) * | 2014-07-21 | 2020-03-30 | Novartis Ag | Treatment of cancer using a cd33 chimeric antigen receptor |
| CN105330750B (zh) * | 2015-11-20 | 2019-02-01 | 上海细胞治疗研究院 | 一种快速中止car-t细胞杀伤作用的分子刹车及其用途 |
-
2017
- 2017-03-17 KR KR1020227005550A patent/KR102499191B1/ko active Active
- 2017-03-17 ES ES17714373T patent/ES2893840T3/es active Active
- 2017-03-17 US US16/086,290 patent/US10875927B2/en active Active
- 2017-03-17 CA CA3015369A patent/CA3015369A1/en active Pending
- 2017-03-17 WO PCT/US2017/023098 patent/WO2017161353A1/en not_active Ceased
- 2017-03-17 DK DK17714373.2T patent/DK3430038T3/da active
- 2017-03-17 CN CN201780018083.9A patent/CN108884144B/zh active Active
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