KR102499191B1 - Cd20 면역요법을 위한 조성물 및 방법 - Google Patents

Cd20 면역요법을 위한 조성물 및 방법 Download PDF

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KR102499191B1
KR102499191B1 KR1020227005550A KR20227005550A KR102499191B1 KR 102499191 B1 KR102499191 B1 KR 102499191B1 KR 1020227005550 A KR1020227005550 A KR 1020227005550A KR 20227005550 A KR20227005550 A KR 20227005550A KR 102499191 B1 KR102499191 B1 KR 102499191B1
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올리버 프레스
브라이언 틸
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프레드 허친슨 캔서 센터
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
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    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
    • A61K40/4221—CD20
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70521—CD28, CD152
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    • A—HUMAN NECESSITIES
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    • A61K2039/507—Comprising a combination of two or more separate antibodies
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the dose, timing or administration schedule
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/48—Blood cells, e.g. leukemia or lymphoma
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies

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KR1020227005550A 2016-03-18 2017-03-17 Cd20 면역요법을 위한 조성물 및 방법 Active KR102499191B1 (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201662310541P 2016-03-18 2016-03-18
US62/310,541 2016-03-18
US201662320327P 2016-04-08 2016-04-08
US62/320,327 2016-04-08
KR1020187026926A KR102366611B1 (ko) 2016-03-18 2017-03-17 Cd20 면역요법을 위한 조성물 및 방법
PCT/US2017/023098 WO2017161353A1 (en) 2016-03-18 2017-03-17 Compositions and methods for cd20 immunotherapy

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EP (2) EP3939994A3 (https=)
JP (2) JP7065782B2 (https=)
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CN (1) CN108884144B (https=)
AU (1) AU2017235657B2 (https=)
BR (1) BR112018067977A8 (https=)
CA (1) CA3015369A1 (https=)
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ES2893840T3 (es) 2022-02-10
JP7397840B2 (ja) 2023-12-13
US20190106501A1 (en) 2019-04-11
BR112018067977A2 (pt) 2019-02-05
CN108884144A (zh) 2018-11-23
IL261316A (en) 2018-10-31
EP3430038A1 (en) 2019-01-23
RU2018134300A3 (https=) 2020-07-15
MX2018010415A (es) 2018-11-29
CN108884144B (zh) 2023-03-14
US20210147569A1 (en) 2021-05-20
JP2019515652A (ja) 2019-06-13
JP2022002550A (ja) 2022-01-11
RU2018134300A (ru) 2020-04-20
WO2017161353A1 (en) 2017-09-21
IL261316B1 (en) 2024-01-01
KR20220030307A (ko) 2022-03-10
KR102366611B1 (ko) 2022-02-23
BR112018067977A8 (pt) 2023-04-11
CA3015369A1 (en) 2017-09-21
US11834511B2 (en) 2023-12-05
KR20180127348A (ko) 2018-11-28
JP7065782B2 (ja) 2022-05-12
EP3939994A2 (en) 2022-01-19
AU2017235657A1 (en) 2018-09-06
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DK3430038T3 (da) 2021-09-13
EP3430038B1 (en) 2021-06-16

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