JP2019515043A5 - - Google Patents

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Publication number
JP2019515043A5
JP2019515043A5 JP2019510575A JP2019510575A JP2019515043A5 JP 2019515043 A5 JP2019515043 A5 JP 2019515043A5 JP 2019510575 A JP2019510575 A JP 2019510575A JP 2019510575 A JP2019510575 A JP 2019510575A JP 2019515043 A5 JP2019515043 A5 JP 2019515043A5
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JP
Japan
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alkyl
disease
independently
och
compound
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JP2019510575A
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English (en)
Japanese (ja)
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JP2019515043A (ja
JP6997766B2 (ja
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Priority claimed from PCT/US2017/031360 external-priority patent/WO2017193034A1/en
Publication of JP2019515043A publication Critical patent/JP2019515043A/ja
Publication of JP2019515043A5 publication Critical patent/JP2019515043A5/ja
Priority to JP2021204755A priority Critical patent/JP7389786B2/ja
Application granted granted Critical
Publication of JP6997766B2 publication Critical patent/JP6997766B2/ja
Priority to JP2023195552A priority patent/JP7755632B2/ja
Priority to JP2025167397A priority patent/JP2026009986A/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2019510575A 2016-05-05 2017-05-05 統合的ストレス経路のモジュレーター Active JP6997766B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2021204755A JP7389786B2 (ja) 2016-05-05 2021-12-17 統合的ストレス経路のモジュレーター
JP2023195552A JP7755632B2 (ja) 2016-05-05 2023-11-17 統合的ストレス経路のモジュレーター
JP2025167397A JP2026009986A (ja) 2016-05-05 2025-10-03 統合的ストレス経路のモジュレーター

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662332278P 2016-05-05 2016-05-05
US62/332,278 2016-05-05
PCT/US2017/031360 WO2017193034A1 (en) 2016-05-05 2017-05-05 Modulators of the integrated stress pathway

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021204755A Division JP7389786B2 (ja) 2016-05-05 2021-12-17 統合的ストレス経路のモジュレーター

Publications (3)

Publication Number Publication Date
JP2019515043A JP2019515043A (ja) 2019-06-06
JP2019515043A5 true JP2019515043A5 (https=) 2020-06-25
JP6997766B2 JP6997766B2 (ja) 2022-01-20

Family

ID=58709639

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2019510575A Active JP6997766B2 (ja) 2016-05-05 2017-05-05 統合的ストレス経路のモジュレーター
JP2021204755A Active JP7389786B2 (ja) 2016-05-05 2021-12-17 統合的ストレス経路のモジュレーター
JP2023195552A Active JP7755632B2 (ja) 2016-05-05 2023-11-17 統合的ストレス経路のモジュレーター
JP2025167397A Pending JP2026009986A (ja) 2016-05-05 2025-10-03 統合的ストレス経路のモジュレーター

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2021204755A Active JP7389786B2 (ja) 2016-05-05 2021-12-17 統合的ストレス経路のモジュレーター
JP2023195552A Active JP7755632B2 (ja) 2016-05-05 2023-11-17 統合的ストレス経路のモジュレーター
JP2025167397A Pending JP2026009986A (ja) 2016-05-05 2025-10-03 統合的ストレス経路のモジュレーター

Country Status (38)

Country Link
US (3) US20190144440A1 (https=)
EP (2) EP3452448B1 (https=)
JP (4) JP6997766B2 (https=)
KR (3) KR20250042188A (https=)
CN (2) CN109641844B (https=)
AR (1) AR110599A1 (https=)
AU (3) AU2017260367B2 (https=)
BR (1) BR112018072663A2 (https=)
CA (1) CA3023162A1 (https=)
CL (1) CL2018003142A1 (https=)
CO (1) CO2018012946A2 (https=)
CR (2) CR20210372A (https=)
DK (1) DK3452448T3 (https=)
DO (1) DOP2018000242A (https=)
EC (1) ECSP18089579A (https=)
ES (1) ES2973442T3 (https=)
FI (1) FI3452448T3 (https=)
HR (1) HRP20240218T1 (https=)
HU (1) HUE065713T2 (https=)
IL (3) IL286693B2 (https=)
LT (1) LT3452448T (https=)
MA (1) MA44861B1 (https=)
MD (1) MD3452448T2 (https=)
MX (2) MX383652B (https=)
MY (1) MY200943A (https=)
PE (2) PE20231935A1 (https=)
PH (1) PH12018502329B1 (https=)
PL (1) PL3452448T3 (https=)
PT (1) PT3452448T (https=)
RS (1) RS65214B1 (https=)
RU (2) RU2022106770A (https=)
SG (1) SG11201809695TA (https=)
SI (1) SI3452448T1 (https=)
SM (1) SMT202400098T1 (https=)
TW (2) TWI763668B (https=)
UA (1) UA125513C2 (https=)
UY (2) UY40873A (https=)
WO (1) WO2017193034A1 (https=)

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US20210145771A1 (en) * 2017-07-03 2021-05-20 Glaxosmithkline Intellectual Property Development Limited N-(3-(2-(4-chlorophenoxy)acetamido)bicyclo[1.1.1] pentan-1-yl)-2-cyclobutane-1- carboxamide derivatives and related compounds as atf4 inhibitors for treating cancer and other diseases
CN118239937A (zh) * 2017-08-09 2024-06-25 戴纳立制药公司 化合物、组合物及方法
DK3676297T3 (da) 2017-09-01 2023-08-14 Denali Therapeutics Inc Forbindelser, sammensætninger og fremgangsmåder
UY37956A (es) * 2017-11-02 2019-05-31 Abbvie Inc Moduladores de la vía de estrés integrada
UY37958A (es) * 2017-11-02 2019-05-31 Abbvie Inc Moduladores de la vía de estrés integrada
US11939320B2 (en) 2017-11-02 2024-03-26 Abbvie Inc. Modulators of the integrated stress pathway
WO2019118785A2 (en) 2017-12-13 2019-06-20 Praxis Biotech LLC Inhibitors of integrated stress response pathway
WO2019183589A1 (en) * 2018-03-23 2019-09-26 Denali Therapeutics Inc. Modulators of eukaryotic initiation factor 2
WO2019236710A1 (en) 2018-06-05 2019-12-12 Praxis Biotech LLC Inhibitors of integrated stress response pathway
JP2021529814A (ja) * 2018-07-09 2021-11-04 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited 化学化合物
TWI877863B (zh) * 2018-10-11 2025-03-21 美商嘉來克生命科學有限責任公司 整合應激路徑之前藥調節劑
MA54953A (fr) * 2019-02-13 2021-12-22 Denali Therapeutics Inc Composés, compositions et procédés
US12091392B2 (en) 2019-02-13 2024-09-17 Denali Therapeutics Inc. Compounds, compositions and methods
US20200270232A1 (en) * 2019-02-25 2020-08-27 Praxis Biotech LLC Inhibitors of integrated stress response pathway
CA3137213A1 (en) 2019-04-23 2020-10-29 Evotec International Gmbh Modulators of the integrated stress response pathway
MX2021012904A (es) 2019-04-23 2022-01-18 Evotec Int Gmbh Moduladores de la via de respuesta al estres integrada.
AR118836A1 (es) * 2019-04-30 2021-11-03 Calico Life Sciences Llc Moduladores de la vía de tensión integrada
MX2021013197A (es) * 2019-04-30 2022-02-24 Calico Life Sciences Llc Cicloalquilos sustituidos como moduladores de la vía integrada del estrés.
JP2022536663A (ja) 2019-06-12 2022-08-18 プラクシス バイオテック エルエルシー 統合的ストレス応答経路のモジュレーター
BR112022010924A2 (pt) * 2019-12-06 2022-09-06 Vertex Pharma Tetra-hidrofuranos substituídos como moduladores de canais de sódio
AU2021213289A1 (en) 2020-01-28 2022-07-07 Evotec International Gmbh Modulators of the integrated stress response pathway
MX2022011143A (es) 2020-03-11 2022-10-13 Evotec Int Gmbh Moduladores de la via de respuesta integrada al estres.
JP2023533016A (ja) 2020-07-11 2023-08-01 ファイザー・インク 抗ウイルス性ヘテロアリールケトン誘導体
US11351149B2 (en) 2020-09-03 2022-06-07 Pfizer Inc. Nitrile-containing antiviral compounds
US20230391763A1 (en) 2020-10-22 2023-12-07 Evotec International Gmbh Modulators of the integrated stress response pathway
MX2023004623A (es) 2020-10-22 2023-05-12 Evotec Int Gmbh Moduladores de la via integrada de respuesta al estres.
JP2023546224A (ja) 2020-10-22 2023-11-01 エヴォテック・インターナショナル・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 統合ストレス応答経路のモジュレーター
CN116685319A (zh) * 2020-12-10 2023-09-01 阿德格罗生物制药控股有限公司 用于治疗皮肤转移性癌的方法
KR20250122004A (ko) * 2024-02-05 2025-08-13 재단법인 대구경북첨단의료산업진흥재단 신규한 eIF2B 작용제 및 이를 포함하는 대사질환 예방 또는 치료용 조성물
WO2025255324A1 (en) * 2024-06-06 2025-12-11 Lapis Therapeutics, Inc. Inhibitors of lipoprotein(a) assembly

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