JP2019519599A5 - - Google Patents
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- JP2019519599A5 JP2019519599A5 JP2019510577A JP2019510577A JP2019519599A5 JP 2019519599 A5 JP2019519599 A5 JP 2019519599A5 JP 2019510577 A JP2019510577 A JP 2019510577A JP 2019510577 A JP2019510577 A JP 2019510577A JP 2019519599 A5 JP2019519599 A5 JP 2019519599A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- disease
- halo
- independently
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662332280P | 2016-05-05 | 2016-05-05 | |
| US62/332,280 | 2016-05-05 | ||
| PCT/US2017/031367 WO2017193041A1 (en) | 2016-05-05 | 2017-05-05 | Modulators of the integrated stress pathway |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019519599A JP2019519599A (ja) | 2019-07-11 |
| JP2019519599A5 true JP2019519599A5 (https=) | 2020-06-25 |
| JP7003114B2 JP7003114B2 (ja) | 2022-01-20 |
Family
ID=58710118
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019510577A Expired - Fee Related JP7003114B2 (ja) | 2016-05-05 | 2017-05-05 | 統合ストレス経路のモジュレーター |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10836725B2 (https=) |
| EP (1) | EP3452453B1 (https=) |
| JP (1) | JP7003114B2 (https=) |
| CN (1) | CN109689628A (https=) |
| AR (1) | AR108393A1 (https=) |
| AU (1) | AU2017260374B2 (https=) |
| CA (1) | CA3023164A1 (https=) |
| ES (1) | ES2923875T3 (https=) |
| MA (1) | MA44866A (https=) |
| TW (1) | TW201808903A (https=) |
| UY (1) | UY37229A (https=) |
| WO (1) | WO2017193041A1 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3071024A1 (en) | 2017-08-09 | 2019-02-14 | Denali Therapeutics Inc. | Compounds, compositions and methods |
| CN111201245B (zh) | 2017-09-01 | 2024-04-05 | 戴纳立制药公司 | 化合物、组合物和方法 |
| WO2019090074A1 (en) * | 2017-11-02 | 2019-05-09 | Calico Life Sciences Llc | Modulators of the integrated stress pathway |
| UY37956A (es) * | 2017-11-02 | 2019-05-31 | Abbvie Inc | Moduladores de la vía de estrés integrada |
| WO2019090088A1 (en) | 2017-11-02 | 2019-05-09 | Calico Life Sciences Llc | Modulators of the integrated stress pathway |
| UY37958A (es) * | 2017-11-02 | 2019-05-31 | Abbvie Inc | Moduladores de la vía de estrés integrada |
| CN111757739A (zh) | 2017-12-13 | 2020-10-09 | 普拉西斯生物技术有限责任公司 | 整合应激反应路径抑制剂 |
| AU2019282253A1 (en) | 2018-06-05 | 2020-11-26 | Altos Labs, Inc. | Inhibitors of integrated stress response pathway |
| WO2020012339A1 (en) * | 2018-07-09 | 2020-01-16 | Glaxosmithkline Intellectual Property Development Limited | Chemical compounds |
| TW202545902A (zh) | 2018-10-11 | 2025-12-01 | 美商嘉來克生命科學有限責任公司 | 整合應激路徑之前藥調節劑 |
| SG11202108552QA (en) | 2019-02-13 | 2021-09-29 | Denali Therapeutics Inc | Compounds, compositions and methods |
| EP3924341A4 (en) | 2019-02-13 | 2022-11-02 | Denali Therapeutics Inc. | Compounds, compositions and methods |
| CA3130511A1 (en) * | 2019-02-25 | 2020-09-03 | Praxis Biotech LLC | Inhibitors of integrated stress response pathway |
| MX2021012904A (es) | 2019-04-23 | 2022-01-18 | Evotec Int Gmbh | Moduladores de la via de respuesta al estres integrada. |
| EP3959198A1 (en) | 2019-04-23 | 2022-03-02 | Evotec International GmbH | Modulators of the integrated stress response pathway |
| WO2020252207A1 (en) | 2019-06-12 | 2020-12-17 | Praxis Biotech LLC | Modulators of integrated stress response pathway |
| JP7699595B2 (ja) | 2020-01-28 | 2025-06-27 | エヴォテック・インターナショナル・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 統合的ストレス応答経路の調節因子 |
| CN115190813B (zh) | 2020-03-11 | 2024-10-15 | 埃沃特克国际有限责任公司 | 整合应激反应途径的调节剂 |
| CA3189027A1 (en) | 2020-07-11 | 2022-01-20 | Pfizer Inc. | Antiviral heteroaryl ketone derivatives |
| US11351149B2 (en) | 2020-09-03 | 2022-06-07 | Pfizer Inc. | Nitrile-containing antiviral compounds |
| RS66455B1 (sr) | 2020-10-22 | 2025-02-28 | Evotec Int Gmbh | Modulatori puta integrisanog odgovora na stres |
| EP4232447A1 (en) | 2020-10-22 | 2023-08-30 | Evotec International GmbH | Modulators of the integrated stress response pathway |
| EP4232153A1 (en) * | 2020-10-22 | 2023-08-30 | Evotec International GmbH | Modulators of the integrated stress response pathway |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JO2397B1 (en) | 2002-12-20 | 2007-06-17 | ميرك شارب اند دوم كوربوريشن | Terazol derivatives as beta-hydroxy steroid dihydrogenase-1 inhibitors |
| JP2007517868A (ja) | 2004-01-07 | 2007-07-05 | アストラゼネカ アクチボラグ | 治療薬ｉ |
| WO2005077900A1 (ja) * | 2004-02-18 | 2005-08-25 | Kyorin Pharmaceutical Co., Ltd. | ビシクロアミド誘導体 |
| JP5133702B2 (ja) * | 2005-01-05 | 2013-01-30 | アボット・ラボラトリーズ | １１−β−ヒドロキシステロイドデヒドロゲナーゼ１型酵素の阻害薬 |
| BRPI0614290A2 (pt) | 2005-08-08 | 2011-03-22 | Argenta Discovery Ltd | derivados de biciclo [ 2.2.1 ] hept-7-ilamina e seus usos |
| WO2011087758A1 (en) | 2009-12-22 | 2011-07-21 | H. Lundbeck A/S | Adamantyl amide derivatives and uses of same |
| TWI538905B (zh) | 2010-12-22 | 2016-06-21 | Ｈ 朗德貝克公司 | 雙環［３．２．１］辛基醯胺衍生物及其用途 |
| CA2904794C (en) * | 2013-03-15 | 2021-11-23 | Peter Walter | Modulators of the eif2alpha pathway |
| US20160318856A1 (en) | 2013-09-11 | 2016-11-03 | The Brigham And Women's Hospital, Inc. | Substituted Urea eIF2alpha Kinase Activators |
-
2017
- 2017-05-04 TW TW106114863A patent/TW201808903A/zh unknown
- 2017-05-05 JP JP2019510577A patent/JP7003114B2/ja not_active Expired - Fee Related
- 2017-05-05 CN CN201780042045.7A patent/CN109689628A/zh active Pending
- 2017-05-05 WO PCT/US2017/031367 patent/WO2017193041A1/en not_active Ceased
- 2017-05-05 MA MA044866A patent/MA44866A/fr unknown
- 2017-05-05 AR ARP170101181A patent/AR108393A1/es unknown
- 2017-05-05 US US16/098,946 patent/US10836725B2/en active Active
- 2017-05-05 UY UY0001037229A patent/UY37229A/es not_active Application Discontinuation
- 2017-05-05 EP EP17724209.6A patent/EP3452453B1/en active Active
- 2017-05-05 ES ES17724209T patent/ES2923875T3/es active Active
- 2017-05-05 CA CA3023164A patent/CA3023164A1/en not_active Abandoned
- 2017-05-05 AU AU2017260374A patent/AU2017260374B2/en not_active Expired - Fee Related
-
2020
- 2020-09-30 US US17/038,179 patent/US20210269399A1/en not_active Abandoned
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