JP2019519599A5 - - Google Patents
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- JP2019519599A5 JP2019519599A5 JP2019510577A JP2019510577A JP2019519599A5 JP 2019519599 A5 JP2019519599 A5 JP 2019519599A5 JP 2019510577 A JP2019510577 A JP 2019510577A JP 2019510577 A JP2019510577 A JP 2019510577A JP 2019519599 A5 JP2019519599 A5 JP 2019519599A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- disease
- halo
- independently
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662332280P | 2016-05-05 | 2016-05-05 | |
| US62/332,280 | 2016-05-05 | ||
| PCT/US2017/031367 WO2017193041A1 (en) | 2016-05-05 | 2017-05-05 | Modulators of the integrated stress pathway |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019519599A JP2019519599A (ja) | 2019-07-11 |
| JP2019519599A5 true JP2019519599A5 (https=) | 2020-06-25 |
| JP7003114B2 JP7003114B2 (ja) | 2022-01-20 |
Family
ID=58710118
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019510577A Expired - Fee Related JP7003114B2 (ja) | 2016-05-05 | 2017-05-05 | 統合ストレス経路のモジュレーター |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10836725B2 (https=) |
| EP (1) | EP3452453B1 (https=) |
| JP (1) | JP7003114B2 (https=) |
| CN (1) | CN109689628A (https=) |
| AR (1) | AR108393A1 (https=) |
| AU (1) | AU2017260374B2 (https=) |
| CA (1) | CA3023164A1 (https=) |
| ES (1) | ES2923875T3 (https=) |
| MA (1) | MA44866A (https=) |
| TW (1) | TW201808903A (https=) |
| UY (1) | UY37229A (https=) |
| WO (1) | WO2017193041A1 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118239937A (zh) | 2017-08-09 | 2024-06-25 | 戴纳立制药公司 | 化合物、组合物及方法 |
| DK3676297T3 (da) | 2017-09-01 | 2023-08-14 | Denali Therapeutics Inc | Forbindelser, sammensætninger og fremgangsmåder |
| UY37956A (es) * | 2017-11-02 | 2019-05-31 | Abbvie Inc | Moduladores de la vía de estrés integrada |
| CA3080804A1 (en) * | 2017-11-02 | 2019-05-09 | Calico Life Sciences Llc | Modulators of the integrated stress pathway |
| UY37958A (es) * | 2017-11-02 | 2019-05-31 | Abbvie Inc | Moduladores de la vía de estrés integrada |
| US11939320B2 (en) | 2017-11-02 | 2024-03-26 | Abbvie Inc. | Modulators of the integrated stress pathway |
| WO2019118785A2 (en) | 2017-12-13 | 2019-06-20 | Praxis Biotech LLC | Inhibitors of integrated stress response pathway |
| WO2019236710A1 (en) | 2018-06-05 | 2019-12-12 | Praxis Biotech LLC | Inhibitors of integrated stress response pathway |
| JP2021529814A (ja) * | 2018-07-09 | 2021-11-04 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ | 化学化合物 |
| TWI877863B (zh) * | 2018-10-11 | 2025-03-21 | 美商嘉來克生命科學有限責任公司 | 整合應激路徑之前藥調節劑 |
| MA54953A (fr) * | 2019-02-13 | 2021-12-22 | Denali Therapeutics Inc | Composés, compositions et procédés |
| US12091392B2 (en) | 2019-02-13 | 2024-09-17 | Denali Therapeutics Inc. | Compounds, compositions and methods |
| US20200270232A1 (en) * | 2019-02-25 | 2020-08-27 | Praxis Biotech LLC | Inhibitors of integrated stress response pathway |
| MX2021012904A (es) | 2019-04-23 | 2022-01-18 | Evotec Int Gmbh | Moduladores de la via de respuesta al estres integrada. |
| CA3137213A1 (en) | 2019-04-23 | 2020-10-29 | Evotec International Gmbh | Modulators of the integrated stress response pathway |
| JP2022536663A (ja) | 2019-06-12 | 2022-08-18 | プラクシス バイオテック エルエルシー | 統合的ストレス応答経路のモジュレーター |
| AU2021213289A1 (en) | 2020-01-28 | 2022-07-07 | Evotec International Gmbh | Modulators of the integrated stress response pathway |
| MX2022011143A (es) | 2020-03-11 | 2022-10-13 | Evotec Int Gmbh | Moduladores de la via de respuesta integrada al estres. |
| JP2023533016A (ja) | 2020-07-11 | 2023-08-01 | ファイザー・インク | 抗ウイルス性ヘテロアリールケトン誘導体 |
| US11351149B2 (en) | 2020-09-03 | 2022-06-07 | Pfizer Inc. | Nitrile-containing antiviral compounds |
| MX2023004623A (es) | 2020-10-22 | 2023-05-12 | Evotec Int Gmbh | Moduladores de la via integrada de respuesta al estres. |
| JP2023546224A (ja) * | 2020-10-22 | 2023-11-01 | エヴォテック・インターナショナル・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 統合ストレス応答経路のモジュレーター |
| US20230391763A1 (en) | 2020-10-22 | 2023-12-07 | Evotec International Gmbh | Modulators of the integrated stress response pathway |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JO2397B1 (en) | 2002-12-20 | 2007-06-17 | ميرك شارب اند دوم كوربوريشن | Terazol derivatives as beta-hydroxy steroid dihydrogenase-1 inhibitors |
| EP1706384A1 (en) | 2004-01-07 | 2006-10-04 | AstraZeneca AB | Therapeutic agents i |
| EP1717225A4 (en) * | 2004-02-18 | 2009-10-21 | Kyorin Seiyaku Kk | BICYCLIC AMID DERIVATIVES |
| CN101142172A (zh) * | 2005-01-05 | 2008-03-12 | 艾博特公司 | 11-β-羟甾类脱氢酶1型酶的抑制剂 |
| JP2009504624A (ja) | 2005-08-08 | 2009-02-05 | アージェンタ ディスカバリー リミテッド | ビシクロ［２．２．１］ヘプタ−７−イルアミン誘導体およびその使用 |
| WO2011087758A1 (en) | 2009-12-22 | 2011-07-21 | H. Lundbeck A/S | Adamantyl amide derivatives and uses of same |
| AR084457A1 (es) | 2010-12-22 | 2013-05-15 | Lundbeck & Co As H | Derivados de biciclo[3,2,1]octilamida |
| JP6806562B2 (ja) | 2013-03-15 | 2021-01-06 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | ｅＩＦ２α経路の調節因子 |
| US20160318856A1 (en) | 2013-09-11 | 2016-11-03 | The Brigham And Women's Hospital, Inc. | Substituted Urea eIF2alpha Kinase Activators |
-
2017
- 2017-05-04 TW TW106114863A patent/TW201808903A/zh unknown
- 2017-05-05 MA MA044866A patent/MA44866A/fr unknown
- 2017-05-05 UY UY0001037229A patent/UY37229A/es not_active Application Discontinuation
- 2017-05-05 US US16/098,946 patent/US10836725B2/en active Active
- 2017-05-05 AU AU2017260374A patent/AU2017260374B2/en not_active Expired - Fee Related
- 2017-05-05 CA CA3023164A patent/CA3023164A1/en not_active Abandoned
- 2017-05-05 EP EP17724209.6A patent/EP3452453B1/en active Active
- 2017-05-05 CN CN201780042045.7A patent/CN109689628A/zh active Pending
- 2017-05-05 ES ES17724209T patent/ES2923875T3/es active Active
- 2017-05-05 JP JP2019510577A patent/JP7003114B2/ja not_active Expired - Fee Related
- 2017-05-05 WO PCT/US2017/031367 patent/WO2017193041A1/en not_active Ceased
- 2017-05-05 AR ARP170101181A patent/AR108393A1/es unknown
-
2020
- 2020-09-30 US US17/038,179 patent/US20210269399A1/en not_active Abandoned
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