JP2019515043A5 - - Google Patents

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Publication number
JP2019515043A5
JP2019515043A5 JP2019510575A JP2019510575A JP2019515043A5 JP 2019515043 A5 JP2019515043 A5 JP 2019515043A5 JP 2019510575 A JP2019510575 A JP 2019510575A JP 2019510575 A JP2019510575 A JP 2019510575A JP 2019515043 A5 JP2019515043 A5 JP 2019515043A5
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JP
Japan
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alkyl
disease
independently
och
compound
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JP2019510575A
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English (en)
Japanese (ja)
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JP2019515043A (ja
JP6997766B2 (ja
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Priority claimed from PCT/US2017/031360 external-priority patent/WO2017193034A1/en
Publication of JP2019515043A publication Critical patent/JP2019515043A/ja
Publication of JP2019515043A5 publication Critical patent/JP2019515043A5/ja
Priority to JP2021204755A priority Critical patent/JP7389786B2/ja
Application granted granted Critical
Publication of JP6997766B2 publication Critical patent/JP6997766B2/ja
Priority to JP2023195552A priority patent/JP7755632B2/ja
Priority to JP2025167397A priority patent/JP2026009986A/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2019510575A 2016-05-05 2017-05-05 統合的ストレス経路のモジュレーター Active JP6997766B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2021204755A JP7389786B2 (ja) 2016-05-05 2021-12-17 統合的ストレス経路のモジュレーター
JP2023195552A JP7755632B2 (ja) 2016-05-05 2023-11-17 統合的ストレス経路のモジュレーター
JP2025167397A JP2026009986A (ja) 2016-05-05 2025-10-03 統合的ストレス経路のモジュレーター

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662332278P 2016-05-05 2016-05-05
US62/332,278 2016-05-05
PCT/US2017/031360 WO2017193034A1 (en) 2016-05-05 2017-05-05 Modulators of the integrated stress pathway

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021204755A Division JP7389786B2 (ja) 2016-05-05 2021-12-17 統合的ストレス経路のモジュレーター

Publications (3)

Publication Number Publication Date
JP2019515043A JP2019515043A (ja) 2019-06-06
JP2019515043A5 true JP2019515043A5 (enExample) 2020-06-25
JP6997766B2 JP6997766B2 (ja) 2022-01-20

Family

ID=58709639

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2019510575A Active JP6997766B2 (ja) 2016-05-05 2017-05-05 統合的ストレス経路のモジュレーター
JP2021204755A Active JP7389786B2 (ja) 2016-05-05 2021-12-17 統合的ストレス経路のモジュレーター
JP2023195552A Active JP7755632B2 (ja) 2016-05-05 2023-11-17 統合的ストレス経路のモジュレーター
JP2025167397A Pending JP2026009986A (ja) 2016-05-05 2025-10-03 統合的ストレス経路のモジュレーター

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2021204755A Active JP7389786B2 (ja) 2016-05-05 2021-12-17 統合的ストレス経路のモジュレーター
JP2023195552A Active JP7755632B2 (ja) 2016-05-05 2023-11-17 統合的ストレス経路のモジュレーター
JP2025167397A Pending JP2026009986A (ja) 2016-05-05 2025-10-03 統合的ストレス経路のモジュレーター

Country Status (38)

Country Link
US (3) US20190144440A1 (enExample)
EP (2) EP3452448B1 (enExample)
JP (4) JP6997766B2 (enExample)
KR (3) KR102512049B1 (enExample)
CN (2) CN109641844B (enExample)
AR (1) AR110599A1 (enExample)
AU (3) AU2017260367B2 (enExample)
BR (1) BR112018072663A2 (enExample)
CA (1) CA3023162A1 (enExample)
CL (1) CL2018003142A1 (enExample)
CO (1) CO2018012946A2 (enExample)
CR (2) CR20210372A (enExample)
DK (1) DK3452448T3 (enExample)
DO (1) DOP2018000242A (enExample)
EC (1) ECSP18089579A (enExample)
ES (1) ES2973442T3 (enExample)
FI (1) FI3452448T3 (enExample)
HR (1) HRP20240218T1 (enExample)
HU (1) HUE065713T2 (enExample)
IL (3) IL286693B2 (enExample)
LT (1) LT3452448T (enExample)
MA (1) MA44861B1 (enExample)
MD (1) MD3452448T2 (enExample)
MX (2) MX2021007146A (enExample)
MY (1) MY200943A (enExample)
PE (2) PE20231935A1 (enExample)
PH (1) PH12018502329B1 (enExample)
PL (1) PL3452448T3 (enExample)
PT (1) PT3452448T (enExample)
RS (1) RS65214B1 (enExample)
RU (2) RU2769327C2 (enExample)
SG (1) SG11201809695TA (enExample)
SI (1) SI3452448T1 (enExample)
SM (1) SMT202400098T1 (enExample)
TW (3) TWI920577B (enExample)
UA (1) UA125513C2 (enExample)
UY (2) UY40873A (enExample)
WO (1) WO2017193034A1 (enExample)

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CN110730777A (zh) * 2017-06-07 2020-01-24 葛兰素史密斯克莱知识产权发展有限公司 作为atf4通路抑制剂的化学化合物
WO2019008506A1 (en) * 2017-07-03 2019-01-10 Glaxosmithkline Intellectual Property Development Limited N- (3- (2- (4-CHLOROPHENOXY) ACETAMIDO) BICYCLO [1.1.1] PENTAN-1-YL) -2-CYCLOBUTANE-1-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS ATF4 INHIBITORS FOR THE TREATMENT OF CANCER AND OTHER DISEASES
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TW201920129A (zh) 2017-09-01 2019-06-01 美商戴納立製藥公司 化合物、組合物及方法
UY37956A (es) * 2017-11-02 2019-05-31 Abbvie Inc Moduladores de la vía de estrés integrada
JP2021501785A (ja) 2017-11-02 2021-01-21 カリコ ライフ サイエンシーズ エルエルシー 統合的ストレス経路の調節剤
UY37958A (es) * 2017-11-02 2019-05-31 Abbvie Inc Moduladores de la vía de estrés integrada
JP2021508336A (ja) 2017-12-13 2021-03-04 プラクシス バイオテック エルエルシー 統合的ストレス応答経路の阻害剤
WO2019183589A1 (en) * 2018-03-23 2019-09-26 Denali Therapeutics Inc. Modulators of eukaryotic initiation factor 2
US11166942B2 (en) 2018-06-05 2021-11-09 Praxis Biotech LLC Inhibitors of integrated stress response pathway
JP2021529814A (ja) * 2018-07-09 2021-11-04 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited 化学化合物
TW202545902A (zh) * 2018-10-11 2025-12-01 美商嘉來克生命科學有限責任公司 整合應激路徑之前藥調節劑
EP3924341A4 (en) 2019-02-13 2022-11-02 Denali Therapeutics Inc. Compounds, compositions and methods
CR20210426A (es) 2019-02-13 2021-09-30 Denali Therapeutics Inc Compuestos, composiciones y métodos
SG11202107871UA (en) * 2019-02-25 2021-08-30 Praxis Biotech LLC Inhibitors of integrated stress response pathway
MX2021012904A (es) 2019-04-23 2022-01-18 Evotec Int Gmbh Moduladores de la via de respuesta al estres integrada.
WO2020216766A1 (en) 2019-04-23 2020-10-29 Evotec International Gmbh Modulators of the integrated stress response pathway
PH12021552759A1 (en) * 2019-04-30 2022-07-04 Abbvie Inc Substituted cycloalkyls as modulators of the integrated stress pathway
AR118836A1 (es) * 2019-04-30 2021-11-03 Calico Life Sciences Llc Moduladores de la vía de tensión integrada
JP2022536663A (ja) 2019-06-12 2022-08-18 プラクシス バイオテック エルエルシー 統合的ストレス応答経路のモジュレーター
PH12022551379A1 (en) * 2019-12-06 2023-05-03 Vertex Pharma Substituted tetrahydrofurans as modulators of sodium channels
CA3162526A1 (en) 2020-01-28 2021-08-05 Christopher John Brown Modulators of the integrated stress response pathway
KR20220151635A (ko) 2020-03-11 2022-11-15 에보텍 인터내셔널 게엠베하 통합 스트레스 반응 경로의 조절제
EP4178955A1 (en) 2020-07-11 2023-05-17 Pfizer Inc. Antiviral heteroaryl ketone derivatives
US11351149B2 (en) 2020-09-03 2022-06-07 Pfizer Inc. Nitrile-containing antiviral compounds
MX2023004677A (es) 2020-10-22 2023-05-24 Evotec Int Gmbh Moduladores de la via de respuesta integrada al estres.
ES2997335T3 (en) 2020-10-22 2025-02-17 Evotec Int Gmbh Modulators of the integrated stress response pathway
CA3195290A1 (en) 2020-10-22 2022-04-28 Holly Victoria Atton Modulators of the integrated stress response pathway
EP4259132A4 (en) * 2020-12-10 2025-01-15 Adgero Biopharmaceuticals Holdings, Inc. METHODS OF TREATMENT OF METASTATIC SKIN CANCER
TW202241857A (zh) 2020-12-18 2022-11-01 美商戴納立製藥公司 化合物之固體形式
KR102992203B1 (ko) * 2024-02-05 2026-07-20 재단법인 대구경북첨단의료산업진흥재단 신규한 eIF2B 작용제 및 이를 포함하는 대사질환 예방 또는 치료용 조성물
WO2025255324A1 (en) * 2024-06-06 2025-12-11 Lapis Therapeutics, Inc. Inhibitors of lipoprotein(a) assembly

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TWI920577B (zh) * 2016-05-05 2026-04-01 美商嘉來克生命科學有限責任公司 整合應激途徑之調節劑

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