JP2019515043A5 - - Google Patents

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Publication number
JP2019515043A5
JP2019515043A5 JP2019510575A JP2019510575A JP2019515043A5 JP 2019515043 A5 JP2019515043 A5 JP 2019515043A5 JP 2019510575 A JP2019510575 A JP 2019510575A JP 2019510575 A JP2019510575 A JP 2019510575A JP 2019515043 A5 JP2019515043 A5 JP 2019515043A5
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JP
Japan
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alkyl
disease
independently
och
compound
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JP2019510575A
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English (en)
Japanese (ja)
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JP6997766B2 (ja
JP2019515043A (ja
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Priority claimed from PCT/US2017/031360 external-priority patent/WO2017193034A1/en
Publication of JP2019515043A publication Critical patent/JP2019515043A/ja
Publication of JP2019515043A5 publication Critical patent/JP2019515043A5/ja
Priority to JP2021204755A priority Critical patent/JP7389786B2/ja
Application granted granted Critical
Publication of JP6997766B2 publication Critical patent/JP6997766B2/ja
Priority to JP2023195552A priority patent/JP7755632B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2019510575A 2016-05-05 2017-05-05 統合的ストレス経路のモジュレーター Active JP6997766B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2021204755A JP7389786B2 (ja) 2016-05-05 2021-12-17 統合的ストレス経路のモジュレーター
JP2023195552A JP7755632B2 (ja) 2016-05-05 2023-11-17 統合的ストレス経路のモジュレーター

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662332278P 2016-05-05 2016-05-05
US62/332,278 2016-05-05
PCT/US2017/031360 WO2017193034A1 (en) 2016-05-05 2017-05-05 Modulators of the integrated stress pathway

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021204755A Division JP7389786B2 (ja) 2016-05-05 2021-12-17 統合的ストレス経路のモジュレーター

Publications (3)

Publication Number Publication Date
JP2019515043A JP2019515043A (ja) 2019-06-06
JP2019515043A5 true JP2019515043A5 (enExample) 2020-06-25
JP6997766B2 JP6997766B2 (ja) 2022-01-20

Family

ID=58709639

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2019510575A Active JP6997766B2 (ja) 2016-05-05 2017-05-05 統合的ストレス経路のモジュレーター
JP2021204755A Active JP7389786B2 (ja) 2016-05-05 2021-12-17 統合的ストレス経路のモジュレーター
JP2023195552A Active JP7755632B2 (ja) 2016-05-05 2023-11-17 統合的ストレス経路のモジュレーター

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2021204755A Active JP7389786B2 (ja) 2016-05-05 2021-12-17 統合的ストレス経路のモジュレーター
JP2023195552A Active JP7755632B2 (ja) 2016-05-05 2023-11-17 統合的ストレス経路のモジュレーター

Country Status (38)

Country Link
US (3) US20190144440A1 (enExample)
EP (2) EP3452448B1 (enExample)
JP (3) JP6997766B2 (enExample)
KR (3) KR102512049B1 (enExample)
CN (2) CN109641844B (enExample)
AR (1) AR110599A1 (enExample)
AU (3) AU2017260367B2 (enExample)
BR (1) BR112018072663A2 (enExample)
CA (1) CA3023162A1 (enExample)
CL (1) CL2018003142A1 (enExample)
CO (1) CO2018012946A2 (enExample)
CR (2) CR20210372A (enExample)
DK (1) DK3452448T3 (enExample)
DO (1) DOP2018000242A (enExample)
EC (1) ECSP18089579A (enExample)
ES (1) ES2973442T3 (enExample)
FI (1) FI3452448T3 (enExample)
HR (1) HRP20240218T1 (enExample)
HU (1) HUE065713T2 (enExample)
IL (3) IL262722B (enExample)
LT (1) LT3452448T (enExample)
MA (1) MA44861B1 (enExample)
MD (1) MD3452448T2 (enExample)
MX (2) MX383652B (enExample)
MY (1) MY200943A (enExample)
PE (2) PE20231935A1 (enExample)
PH (1) PH12018502329B1 (enExample)
PL (1) PL3452448T3 (enExample)
PT (1) PT3452448T (enExample)
RS (1) RS65214B1 (enExample)
RU (2) RU2022106770A (enExample)
SG (1) SG11201809695TA (enExample)
SI (1) SI3452448T1 (enExample)
SM (1) SMT202400098T1 (enExample)
TW (3) TW202506629A (enExample)
UA (1) UA125513C2 (enExample)
UY (1) UY37228A (enExample)
WO (1) WO2017193034A1 (enExample)

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US20210145771A1 (en) * 2017-07-03 2021-05-20 Glaxosmithkline Intellectual Property Development Limited N-(3-(2-(4-chlorophenoxy)acetamido)bicyclo[1.1.1] pentan-1-yl)-2-cyclobutane-1- carboxamide derivatives and related compounds as atf4 inhibitors for treating cancer and other diseases
CN111094233B (zh) 2017-08-09 2024-03-15 戴纳立制药公司 化合物、组合物及方法
PT3676297T (pt) 2017-09-01 2023-08-29 Denali Therapeutics Inc Compostos, composições e métodos
JP2021501785A (ja) 2017-11-02 2021-01-21 カリコ ライフ サイエンシーズ エルエルシー 統合的ストレス経路の調節剤
UY37956A (es) * 2017-11-02 2019-05-31 Abbvie Inc Moduladores de la vía de estrés integrada
UY37958A (es) * 2017-11-02 2019-05-31 Abbvie Inc Moduladores de la vía de estrés integrada
RU2020122711A (ru) * 2017-12-13 2022-01-17 ПРАКСИС БАЙОТЕК ЭлЭлСи Ингибиторы пути интегрированной реакции на стресс
US20210130308A1 (en) * 2018-03-23 2021-05-06 Denali Therapeutics Inc. Modulators of eukaryotic initiation factor 2
SG11202011014VA (en) 2018-06-05 2020-12-30 Praxis Biotech LLC Inhibitors of integrated stress response pathway
JP2021529814A (ja) * 2018-07-09 2021-11-04 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited 化学化合物
TWI832295B (zh) * 2018-10-11 2024-02-11 美商嘉來克生命科學有限責任公司 整合應激路徑之前藥調節劑
MA54959A (fr) 2019-02-13 2021-12-22 Denali Therapeutics Inc Composés, compositions et procédés
CA3129609A1 (en) * 2019-02-13 2020-08-20 Denali Therapeutics Inc. Eukaryotic initiation factor 2b modulators
KR20210134351A (ko) * 2019-02-25 2021-11-09 프락시스 바이오테크 엘엘씨 통합 스트레스 반응 경로의 억제제
EA202192900A1 (ru) 2019-04-23 2022-03-18 Эвотек Интернешнл Гмбх Модуляторы пути интегрированной реакции на стресс
AU2020261234A1 (en) 2019-04-23 2021-11-11 Evotec International Gmbh Modulators of the integrated stress response pathway
AU2020266592A1 (en) * 2019-04-30 2021-12-02 Abbvie Inc. Substituted cyclolakyls as modulators of the integrated stress pathway
PH12021552759A1 (en) * 2019-04-30 2022-07-04 Abbvie Inc Substituted cycloalkyls as modulators of the integrated stress pathway
CA3142748A1 (en) 2019-06-12 2020-12-17 Praxis Biotech LLC Modulators of integrated stress response pathway
PH12022551379A1 (en) * 2019-12-06 2023-05-03 Vertex Pharma Substituted tetrahydrofurans as modulators of sodium channels
KR20220133252A (ko) 2020-01-28 2022-10-04 에보텍 인터내셔널 게엠베하 통합 스트레스 반응 경로의 조절자
JP2023517944A (ja) 2020-03-11 2023-04-27 エヴォテック・インターナショナル・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 統合的ストレス応答経路の調節因子
US11351149B2 (en) 2020-09-03 2022-06-07 Pfizer Inc. Nitrile-containing antiviral compounds
AU2021366303A1 (en) 2020-10-22 2023-06-22 Evotec International Gmbh Modulators of the integrated stress response pathway
US20230391763A1 (en) 2020-10-22 2023-12-07 Evotec International Gmbh Modulators of the integrated stress response pathway
CA3195290A1 (en) 2020-10-22 2022-04-28 Holly Victoria Atton Modulators of the integrated stress response pathway
JP2023553149A (ja) * 2020-12-10 2023-12-20 アジェロ・バイオファーマシューティカルズ・ホールディングス・インコーポレイテッド 皮膚転移性がんを治療する方法
KR20250122004A (ko) * 2024-02-05 2025-08-13 재단법인 대구경북첨단의료산업진흥재단 신규한 eIF2B 작용제 및 이를 포함하는 대사질환 예방 또는 치료용 조성물

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