JP2019515043A5 - - Google Patents
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- JP2019515043A5 JP2019515043A5 JP2019510575A JP2019510575A JP2019515043A5 JP 2019515043 A5 JP2019515043 A5 JP 2019515043A5 JP 2019510575 A JP2019510575 A JP 2019510575A JP 2019510575 A JP2019510575 A JP 2019510575A JP 2019515043 A5 JP2019515043 A5 JP 2019515043A5
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Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021204755A JP7389786B2 (ja) | 2016-05-05 | 2021-12-17 | 統合的ストレス経路のモジュレーター |
| JP2023195552A JP7755632B2 (ja) | 2016-05-05 | 2023-11-17 | 統合的ストレス経路のモジュレーター |
| JP2025167397A JP2026009986A (ja) | 2016-05-05 | 2025-10-03 | 統合的ストレス経路のモジュレーター |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662332278P | 2016-05-05 | 2016-05-05 | |
| US62/332,278 | 2016-05-05 | ||
| PCT/US2017/031360 WO2017193034A1 (en) | 2016-05-05 | 2017-05-05 | Modulators of the integrated stress pathway |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021204755A Division JP7389786B2 (ja) | 2016-05-05 | 2021-12-17 | 統合的ストレス経路のモジュレーター |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019515043A JP2019515043A (ja) | 2019-06-06 |
| JP2019515043A5 true JP2019515043A5 (enExample) | 2020-06-25 |
| JP6997766B2 JP6997766B2 (ja) | 2022-01-20 |
Family
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Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019510575A Active JP6997766B2 (ja) | 2016-05-05 | 2017-05-05 | 統合的ストレス経路のモジュレーター |
| JP2021204755A Active JP7389786B2 (ja) | 2016-05-05 | 2021-12-17 | 統合的ストレス経路のモジュレーター |
| JP2023195552A Active JP7755632B2 (ja) | 2016-05-05 | 2023-11-17 | 統合的ストレス経路のモジュレーター |
| JP2025167397A Pending JP2026009986A (ja) | 2016-05-05 | 2025-10-03 | 統合的ストレス経路のモジュレーター |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021204755A Active JP7389786B2 (ja) | 2016-05-05 | 2021-12-17 | 統合的ストレス経路のモジュレーター |
| JP2023195552A Active JP7755632B2 (ja) | 2016-05-05 | 2023-11-17 | 統合的ストレス経路のモジュレーター |
| JP2025167397A Pending JP2026009986A (ja) | 2016-05-05 | 2025-10-03 | 統合的ストレス経路のモジュレーター |
Country Status (38)
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112019025883A2 (pt) * | 2017-06-07 | 2020-06-30 | Glaxosmithkline Intellectual Property Development Limited | compostos químicos como inibidores da via de atf4 |
| BR112020000122A2 (pt) * | 2017-07-03 | 2020-07-07 | Glaxosmithkline Intellectual Property Development Limited | derivados da n-(3-(2-(4-clorofenóxi)acetamido)biciclo[1.1.1] pentan-1-il)-2-ciclobutano-1-carboxamida e compostos relacionados como inibidores do atf4 para tratamento contra o câncer e outras doenças |
| MA49858A (fr) * | 2017-08-09 | 2021-04-28 | Denali Therapeutics Inc | Composés, compositions et procédés |
| DK3676297T3 (da) | 2017-09-01 | 2023-08-14 | Denali Therapeutics Inc | Forbindelser, sammensætninger og fremgangsmåder |
| UY37958A (es) * | 2017-11-02 | 2019-05-31 | Abbvie Inc | Moduladores de la vía de estrés integrada |
| UY37956A (es) * | 2017-11-02 | 2019-05-31 | Abbvie Inc | Moduladores de la vía de estrés integrada |
| CA3080971A1 (en) | 2017-11-02 | 2019-05-09 | Calico Life Sciences Llc | Modulators of the integrated stress pathway |
| EP3723762A4 (en) * | 2017-12-13 | 2021-12-08 | Praxis Biotech LLC | STRESS INTEGRATED RESPONSE PATH INHIBITORS |
| WO2019183589A1 (en) * | 2018-03-23 | 2019-09-26 | Denali Therapeutics Inc. | Modulators of eukaryotic initiation factor 2 |
| BR112020023115A2 (pt) | 2018-06-05 | 2021-02-02 | Praxis Biotech LLC | inibidores da via integrada de resposta a tensão |
| EP3820843A1 (en) * | 2018-07-09 | 2021-05-19 | GlaxoSmithKline Intellectual Property Development Limited | Chemical compounds |
| TWI832295B (zh) * | 2018-10-11 | 2024-02-11 | 美商嘉來克生命科學有限責任公司 | 整合應激路徑之前藥調節劑 |
| SG11202108552QA (en) * | 2019-02-13 | 2021-09-29 | Denali Therapeutics Inc | Compounds, compositions and methods |
| MA54959A (fr) | 2019-02-13 | 2021-12-22 | Denali Therapeutics Inc | Composés, compositions et procédés |
| US20200270232A1 (en) * | 2019-02-25 | 2020-08-27 | Praxis Biotech LLC | Inhibitors of integrated stress response pathway |
| IL287379B2 (en) | 2019-04-23 | 2025-11-01 | Evotec Int Gmbh | Modulators of the integrated stress response pathway |
| AU2020262153B2 (en) | 2019-04-23 | 2026-01-22 | Evotec International Gmbh | Modulators of the integrated stress response pathway |
| KR20220016467A (ko) * | 2019-04-30 | 2022-02-09 | 칼리코 라이프 사이언시스 엘엘씨 | 통합된 스트레스 경로의 조절인자로서 치환된 사이클로알킬 |
| US20200347043A1 (en) * | 2019-04-30 | 2020-11-05 | Calico Life Sciences Llc | Modulators of the integrated stress pathway |
| CA3142748A1 (en) | 2019-06-12 | 2020-12-17 | Praxis Biotech LLC | Modulators of integrated stress response pathway |
| DK4069691T3 (da) | 2019-12-06 | 2024-10-28 | Vertex Pharma | Substituerede tetrahydrofuraner som modulatorer af natriumkanaler |
| US20230125481A1 (en) | 2020-01-28 | 2023-04-27 | Evotec International Gmbh | Modulators of the integrated stress response pathway |
| EP4117780A1 (en) | 2020-03-11 | 2023-01-18 | Evotec International GmbH | Modulators of the integrated stress response pathway |
| US12577240B2 (en) | 2020-07-11 | 2026-03-17 | Pfizer Inc. | Antiviral heteroaryl ketone derivatives |
| US11351149B2 (en) | 2020-09-03 | 2022-06-07 | Pfizer Inc. | Nitrile-containing antiviral compounds |
| MX2023004677A (es) | 2020-10-22 | 2023-05-24 | Evotec Int Gmbh | Moduladores de la via de respuesta integrada al estres. |
| PL4232154T3 (pl) | 2020-10-22 | 2025-02-24 | Evotec International Gmbh | Modulatory zintegrowanego szlaku odpowiedzi na stres |
| CA3195290A1 (en) | 2020-10-22 | 2022-04-28 | Holly Victoria Atton | Modulators of the integrated stress response pathway |
| WO2022125774A1 (en) * | 2020-12-10 | 2022-06-16 | Adgero Biopharmaceuticals Holdings, Inc. | Methods for treating cutaneous metastatic cancers |
| KR20250122004A (ko) * | 2024-02-05 | 2025-08-13 | 재단법인 대구경북첨단의료산업진흥재단 | 신규한 eIF2B 작용제 및 이를 포함하는 대사질환 예방 또는 치료용 조성물 |
Family Cites Families (18)
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|---|---|---|---|---|
| US5212A (en) | 1847-07-31 | Richard m | ||
| US162A (en) | 1837-04-17 | Island | ||
| US4911920A (en) | 1986-07-30 | 1990-03-27 | Alcon Laboratories, Inc. | Sustained release, comfort formulation for glaucoma therapy |
| FR2588189B1 (fr) | 1985-10-03 | 1988-12-02 | Merck Sharp & Dohme | Composition pharmaceutique de type a transition de phase liquide-gel |
| JP2594486B2 (ja) | 1991-01-15 | 1997-03-26 | アルコン ラボラトリーズ インコーポレイテッド | 局所的眼薬組成物 |
| GB0400196D0 (en) * | 2004-01-07 | 2004-02-11 | Astrazeneca Ab | Therapeutic agents |
| JP2007517868A (ja) | 2004-01-07 | 2007-07-05 | アストラゼネカ アクチボラグ | 治療薬ｉ |
| AU2005267093B2 (en) | 2004-07-23 | 2009-10-01 | Nuada Llc | Peptidase inhibitors |
| GB0516314D0 (en) * | 2005-08-08 | 2005-09-14 | Argenta Discovery Ltd | Compound |
| RU2442771C2 (ru) | 2005-08-08 | 2012-02-20 | Арджента Дискавери Лтд | Производные бицикло[2,2,1]гепт-7-иламина и их применения |
| CA2618103A1 (en) | 2005-08-10 | 2007-02-15 | Pfizer Limited | Substituted triazole derivatives as oxytocin antagonists |
| CN103122001A (zh) * | 2007-09-25 | 2013-05-29 | 武田药品工业株式会社 | Polo样激酶抑制剂 |
| US8741894B2 (en) * | 2010-03-17 | 2014-06-03 | Axikin Pharmaceuticals, Inc. | Arylsulfonamide CCR3 antagonists |
| CN103025725B (zh) | 2010-08-10 | 2015-09-16 | 安斯泰来制药有限公司 | 杂环化合物 |
| AR084457A1 (es) * | 2010-12-22 | 2013-05-15 | Lundbeck & Co As H | Derivados de biciclo[3,2,1]octilamida |
| CA2904794C (en) * | 2013-03-15 | 2021-11-23 | Peter Walter | Modulators of the eif2alpha pathway |
| WO2015038778A1 (en) * | 2013-09-11 | 2015-03-19 | The Brigham And Women's Hospital, Inc. | SUBSTITUTED UREA EIF2α KINASE ACTIVATORS |
| LT3126352T (lt) * | 2014-04-04 | 2019-01-10 | Syros Pharmaceuticals, Inc. | Nuo ciklino priklausomos kinazės 7 (cdk7) inhibitoriai |
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