KR102512049B1 - 통합된 스트레스 경로의 조절제 - Google Patents

통합된 스트레스 경로의 조절제 Download PDF

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KR102512049B1
KR102512049B1 KR1020187035249A KR20187035249A KR102512049B1 KR 102512049 B1 KR102512049 B1 KR 102512049B1 KR 1020187035249 A KR1020187035249 A KR 1020187035249A KR 20187035249 A KR20187035249 A KR 20187035249A KR 102512049 B1 KR102512049 B1 KR 102512049B1
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KR20190031203A (ko
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카멜라 시드라우스키
마리나 플뤼쉬체브
제니퍼 엠. 프로스트
로렌스 에이. 블랙
시앙동 쉬
람지 파라스 스와이스
레이 시
칭웨이 장
윤송 통
찰스 더블유. 허친스
승원 정
마이클 제이. 다트
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칼리코 라이프 사이언시스 엘엘씨
애브비 인코포레이티드
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
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    • C07C237/48—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring being part of a condensed ring system of the same carbon skeleton
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    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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