JP2019512475A5 - - Google Patents
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- JP2019512475A5 JP2019512475A5 JP2018546423A JP2018546423A JP2019512475A5 JP 2019512475 A5 JP2019512475 A5 JP 2019512475A5 JP 2018546423 A JP2018546423 A JP 2018546423A JP 2018546423 A JP2018546423 A JP 2018546423A JP 2019512475 A5 JP2019512475 A5 JP 2019512475A5
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- JP
- Japan
- Prior art keywords
- compound
- disease
- integer
- compound according
- ammonium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662303960P | 2016-03-04 | 2016-03-04 | |
| US62/303,960 | 2016-03-04 | ||
| PCT/US2017/020477 WO2017151938A1 (en) | 2016-03-04 | 2017-03-02 | Prevention, treatment and reversal of disease using therapeutically effective amounts of dicarboxylic acid compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019512475A JP2019512475A (ja) | 2019-05-16 |
| JP2019512475A5 true JP2019512475A5 (https=) | 2020-04-09 |
| JP6959246B2 JP6959246B2 (ja) | 2021-11-02 |
Family
ID=59743189
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018546423A Active JP6959246B2 (ja) | 2016-03-04 | 2017-03-02 | 治療に有効な量のジカルボン酸化合物を使用した、病気の予防、治療及び治癒 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US10751310B2 (https=) |
| EP (1) | EP3440045B1 (https=) |
| JP (1) | JP6959246B2 (https=) |
| CN (1) | CN109071405A (https=) |
| CA (1) | CA3016180A1 (https=) |
| WO (1) | WO2017151938A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10765652B2 (en) | 2016-10-05 | 2020-09-08 | University of Pittsburgh—of the Commonwealth System of Higher Education | Reversible nitroxide derivatives of nitroalkenes that mediate nitrosating and alkylating reactions |
| JP2019529501A (ja) | 2016-10-05 | 2019-10-17 | ユニバーシティ オブ ピッツバーグ−オブ ザ コモンウェルス システム オブ ハイヤー エデュケーションＵｎｉｖｅｒｓｉｔｙ Ｏｆ Ｐｉｔｔｓｂｕｒｇｈ Ｏｆ Ｔｈｅ Ｃｏｍｍｏｎｗｅａｌｔｈ Ｓｙｓｔｅｍ Ｏｆ Ｈｉｇｈｅｒ Ｅｄｕｃａｔｉｏｎ | 可逆的に保護された、チオレート化求電子性脂肪酸としてのプロドラッグ |
| CN109200043A (zh) * | 2018-10-23 | 2019-01-15 | 华南农业大学 | 二羧酸（盐）在降低脂肪沉积和预防肥胖方面的应用 |
| CN112996493A (zh) * | 2018-11-14 | 2021-06-18 | 高等教育联邦系统-匹兹堡大学 | 作为rad51抑制剂的亲电试剂和亲电前药 |
| CA3209453A1 (en) * | 2021-01-25 | 2022-07-28 | Espervita Therapeutics, Inc. | Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives therof, and their use for the prevention or treatment of disease |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1153464A (en) * | 1965-08-25 | 1969-05-29 | Lepetit Spa | Amino-Fluoro-Aliphatic Dicarboxylic Acids and a process for their preparation |
| US3527789A (en) * | 1967-10-06 | 1970-09-08 | Shell Oil Co | Production of poly(lower)alkyl alkenepolycarboxylates |
| US4166913A (en) * | 1977-07-08 | 1979-09-04 | Atlantic Richfield Company | Preparation of unsaturated diesters by the catalytic oxidative carbonylation of diolefins with an enol ether and an alcohol |
| EP0344113A3 (de) | 1988-05-27 | 1990-10-31 | Ciba-Geigy Ag | Substituierte alpha-Pyrone und Naphthochinone |
| US6528499B1 (en) | 2000-04-27 | 2003-03-04 | Georgetown University | Ligands for metabotropic glutamate receptors and inhibitors of NAALADase |
| EP2679224A1 (en) | 2007-08-01 | 2014-01-01 | University of Pittsburgh of the Commonwealth System of Higher Education | Nitro oleic acid modulation of type II diabetes |
| EP2100604B1 (en) * | 2008-03-10 | 2012-07-04 | Nestec S.A. | Medium chain dicarboxylic acids and their derivates and metabolic disorders |
| WO2010005521A1 (en) | 2008-06-30 | 2010-01-14 | Bltn, Llc | Azelaic acid ester compositions and methods for diagnosing and treating tissue conditions using azelaic acid ester compositions and proteinaceous biomarkers |
| WO2010014889A2 (en) | 2008-08-01 | 2010-02-04 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Nitro fatty acids as regiomers and related mimetics |
| EP2459189A4 (en) | 2009-07-31 | 2013-01-16 | Univ Pittsburgh | FATTY ACIDS AS ANTI-INFLAMMATORY AGENTS |
| DE102011118462B4 (de) | 2011-11-14 | 2021-07-22 | Maximilian Born | Energetische Polymere als reaktive Strukturmaterialien zur Verwendung für Waffensysteme |
| EP2809317A4 (en) | 2012-02-03 | 2015-07-22 | Univ Pittsburgh | FATTY ACIDS AS ANTI-INFLAMMATORY ACTIVE SUBSTANCES |
| WO2013142206A1 (en) * | 2012-03-21 | 2013-09-26 | P2 Science, Inc. | Guerbet alcohols and methods for preparing and using same |
| WO2013162924A1 (en) * | 2012-04-24 | 2013-10-31 | Stepan Company | Synergistic surfactant blends |
| WO2015012367A1 (ja) * | 2013-07-26 | 2015-01-29 | 宇部興産株式会社 | トリカルボン酸、トリカルボン酸エステル、およびそれらを含有する電解コンデンサ用電解液 |
| TWI515296B (zh) * | 2013-10-11 | 2016-01-01 | 中央研究院 | 反式－烏頭酸化合物於抑制第七型磷酸二酯酶的用途及於製備藥品與保健食品的用途 |
| CN103705499B (zh) * | 2013-12-13 | 2015-11-18 | 南京医科大学 | 二羧酸及其酯类化合物的应用 |
| US20150216825A1 (en) * | 2014-02-06 | 2015-08-06 | University Of Houston System | Organic acids as growth inhibitors of pathological calcification and uses thereof |
-
2017
- 2017-03-02 EP EP17760831.2A patent/EP3440045B1/en active Active
- 2017-03-02 JP JP2018546423A patent/JP6959246B2/ja active Active
- 2017-03-02 CA CA3016180A patent/CA3016180A1/en active Pending
- 2017-03-02 WO PCT/US2017/020477 patent/WO2017151938A1/en not_active Ceased
- 2017-03-02 CN CN201780024057.7A patent/CN109071405A/zh active Pending
- 2017-03-02 US US16/081,791 patent/US10751310B2/en active Active
-
2020
- 2020-07-27 US US16/940,119 patent/US11642325B2/en active Active
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