|
US7393682B1
(en)
|
1993-03-19 |
2008-07-01 |
The Johns Hopkins University School Of Medicine |
Polynucleotides encoding promyostatin polypeptides
|
|
DK0698094T3
(da)
|
1993-05-12 |
2004-05-03 |
Inst Genetics Llc |
BMP-11-sammensætninger
|
|
US6008434A
(en)
|
1994-07-08 |
1999-12-28 |
Johns Hopkins University School Of Medicine |
Growth differentiation factor-11 transgenic mice
|
|
WO1996001845A1
(en)
|
1994-07-08 |
1996-01-25 |
The Johns Hopkins University School Of Medicine |
Growth differentiation factor-11
|
|
US20030167492A1
(en)
|
1994-07-08 |
2003-09-04 |
Johns Hopkins University School Of Medicine |
Transgenic non-human animals expressing a gdf-11 dominant negative polypeptide, and methods of making and using same
|
|
CA2291514C
(en)
|
1997-05-30 |
2011-07-12 |
Mariel Therapeutics, Inc. |
Methods for evaluating tissue morphogenesis and activity
|
|
US6696260B1
(en)
|
1997-08-01 |
2004-02-24 |
The Johns Hopkins University School Of Medicine |
Methods to identify growth differentiation factor (GDF) binding proteins
|
|
US6656475B1
(en)
|
1997-08-01 |
2003-12-02 |
The Johns Hopkins University School Of Medicine |
Growth differentiation factor receptors, agonists and antagonists thereof, and methods of using same
|
|
US6891082B2
(en)
*
|
1997-08-01 |
2005-05-10 |
The Johns Hopkins University School Of Medicine |
Transgenic non-human animals expressing a truncated activintype II receptor
|
|
US7795202B2
(en)
|
1997-08-04 |
2010-09-14 |
Neurorepair, Inc. |
Methods for treating a neurological disorder by peripheral administration of a transforming growth factor alpha (TGF-a)
|
|
US6953662B2
(en)
|
1997-08-29 |
2005-10-11 |
Human Genome Sciences, Inc. |
Follistatin-3
|
|
WO1999024057A2
(en)
|
1997-11-07 |
1999-05-20 |
Genetics Inst |
Neuronal uses of bmp-11
|
|
US20030170213A1
(en)
|
1998-01-23 |
2003-09-11 |
Marc F. Charette |
Methods and compositions for enhancing cognitive function using morphogenic proteins
|
|
ES2318900T3
(es)
|
1998-07-15 |
2009-05-01 |
Metamorphix, Inc. |
Promotor del factor de diferenciacion del crecimiento y sus usos.
|
|
US7572440B2
(en)
|
1999-07-30 |
2009-08-11 |
Stryker Corporation |
Method for repairing a defect in an intervertebral disc
|
|
US20030224501A1
(en)
|
2000-03-17 |
2003-12-04 |
Young Paul E. |
Bone morphogenic protein polynucleotides, polypeptides, and antibodies
|
|
US20030104977A1
(en)
|
2000-03-31 |
2003-06-05 |
Ugo Ripamonti |
Methods for inducing angiogenesis using morphogenic proteins and stimulatory factors
|
|
EP1790726B1
(en)
|
2001-02-08 |
2013-07-03 |
Wyeth LLC |
Modified and stabilized GDF propeptides and uses thereof
|
|
TWI329129B
(en)
|
2001-02-08 |
2010-08-21 |
Wyeth Corp |
Modified and stabilized gdf propeptides and uses thereof
|
|
US20060078532A1
(en)
|
2004-10-12 |
2006-04-13 |
Omoigui Osemwota S |
Method of prevention and treatment of Atherosclerosis, Peripheral vascular disease, Coronary artery disease, aging and age-related disorders including osteoporosis, arthritis, type 2 diabetes, dementia and Alzheimer's disease
|
|
US20070155661A1
(en)
*
|
2003-02-14 |
2007-07-05 |
The Board Of Trustees Of The Leland Standord Junior University |
Methods and compositions for modulating the development of stem cells
|
|
NZ529860A
(en)
|
2003-11-28 |
2006-10-27 |
Ovita Ltd |
Muscle growth regulator mighty and use in promoting muscle mass and treating muscle wasting diseases
|
|
US7388027B2
(en)
|
2004-03-04 |
2008-06-17 |
Bristol-Myers Squibb Company |
Bicyclic compounds as modulators of androgen receptor function and method
|
|
US20070178095A1
(en)
|
2004-03-23 |
2007-08-02 |
Eli Lilly And Company |
Anti-myostatin antibodies
|
|
EP3489257A1
(en)
|
2004-07-23 |
2019-05-29 |
Acceleron Pharma Inc. |
Actrii receptor polypeptides, methods and compositions
|
|
US20060216279A1
(en)
|
2005-03-22 |
2006-09-28 |
Glass David J |
Myostatin inhibiting fusion polypeptides and therapeutic methods thereof
|
|
EP1877075A4
(en)
|
2005-04-25 |
2008-07-30 |
Pfizer |
ANTIBODY TO MYOSTATIN
|
|
US20090215671A1
(en)
|
2005-05-27 |
2009-08-27 |
The Regents Of The University Of California |
Compositions And Methods For Treatment of Neural Disorders Using Transforming Growth Factor-Beta Superfamily Proteins And Their Antagonists
|
|
PL2407486T3
(pl)
|
2005-08-19 |
2018-05-30 |
Wyeth Llc |
Przeciwciała antagonistyczne względem GDF-8 i zastosowania w leczeniu ALS i innych zaburzeń związanych z GDF-8
|
|
US8067562B2
(en)
|
2005-11-01 |
2011-11-29 |
Amgen Inc. |
Isolated nucleic acid molecule comprising the amino acid sequence of SEQ ID NO:1
|
|
US7972599B2
(en)
|
2006-03-20 |
2011-07-05 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
Immunomodulation of inflammatory conditions utilizing Follistatin-like protein-1 and agents that bind thereto
|
|
US20080044387A1
(en)
|
2006-03-24 |
2008-02-21 |
The Regents Of The University Of California |
Artificial niches for enhancement of regenerative capacity of stem cells in aged and pathological environments
|
|
AU2007257208B2
(en)
|
2006-05-17 |
2013-05-02 |
Stryker Corporation |
Use of a soluble morphogenic protein complex for treating cartilage defects
|
|
WO2008021196A2
(en)
|
2006-08-09 |
2008-02-21 |
The Mclean Hospital Corporation |
Methods and compositions for the treatment of medical disorders
|
|
US7947646B2
(en)
|
2007-03-06 |
2011-05-24 |
Amgen Inc. |
Variant activin receptor polypeptides
|
|
US8404656B2
(en)
*
|
2007-08-09 |
2013-03-26 |
Children's Hospital Medical Center |
Methods of treatment and prevention of diet-induced obesity and sequelae thereof
|
|
AU2008352925A1
(en)
|
2008-03-20 |
2009-09-24 |
Transmolecular, Inc. |
Inhibition of angiogenesis
|
|
US8216997B2
(en)
|
2008-08-14 |
2012-07-10 |
Acceleron Pharma, Inc. |
Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators
|
|
US8969081B2
(en)
|
2008-12-10 |
2015-03-03 |
The Trustees Of Columbia University In The City Of New York |
Caudal motor neuron derived from embryonic stem cells under conditions essentially free of any retinoid
|
|
US8952130B2
(en)
|
2009-02-24 |
2015-02-10 |
The Salk Institute For Biological Studies |
Designer ligands of TGF-β superfamily
|
|
WO2011130347A2
(en)
|
2010-04-13 |
2011-10-20 |
The Johns Hopkins University |
Methods for enhancing axonal regeneration
|
|
WO2012135623A1
(en)
|
2011-03-31 |
2012-10-04 |
Theravasc Inc. |
Use of nitrites for the treatment of cerebral amyloid angiopathy, age associated dementia, and cognitive decline
|
|
US8765385B2
(en)
*
|
2011-10-27 |
2014-07-01 |
Ravindra Kumar |
Method of detection of neutralizing anti-actriib antibodies
|
|
US9434779B2
(en)
|
2012-03-19 |
2016-09-06 |
The Brigham And Women's Hospital, Inc. |
Growth differentiation factor 11 (GDF-11) for treatment of diastolic heart failure
|
|
US10092627B2
(en)
|
2013-04-08 |
2018-10-09 |
President And Fellows Of Harvard College |
Methods and compositions for rejuvenating skeletal muscle stem cells
|
|
KR102580225B1
(ko)
|
2013-06-11 |
2023-09-20 |
프레지던트 앤드 펠로우즈 오브 하바드 칼리지 |
SC-β 세포 및 조성물 그리고 그 생성 방법
|
|
EP3007719B1
(en)
|
2013-06-11 |
2021-03-17 |
President and Fellows of Harvard College |
Methods and compositions for increasing neurogenesis and angiogenesis
|
|
ES2767050T3
(es)
|
2013-09-03 |
2020-06-16 |
Mayo Found Medical Education & Res |
Reducción del riesgo de eventos cardíacos adversos mayores
|
|
US20160287667A1
(en)
|
2013-11-08 |
2016-10-06 |
President And Fellows Of Harvard College |
Methods and compositions for rejuvenating neuromuscular junctions
|
|
WO2015073396A1
(en)
|
2013-11-12 |
2015-05-21 |
The Brigham And Women's Hospital, Inc. |
Growth differentiation factor (gdf) for treatment of diastolic heart failure
|
|
US20170073406A1
(en)
|
2014-05-06 |
2017-03-16 |
Scholar Rock, Inc. |
Compositions and methods for growth factor modulation
|
|
WO2016049662A1
(en)
|
2014-09-23 |
2016-03-31 |
President And Fellows Of Harvard College |
Methods and compositions for treating age-related disorders
|
|
ES2893813T3
(es)
|
2016-01-06 |
2022-02-10 |
Harvard College |
El tratamiento con GDF11 previene el aumento de peso, mejora la tolerancia a la glucosa y reduce la hepatoesteatosis
|
|
US10941195B2
(en)
|
2016-10-04 |
2021-03-09 |
Fairbanks Pharmaceuticals, Inc. |
Anti-follistatin-like 3 antibodies and treatment of diabetes
|
|
WO2019144053A1
(en)
|
2018-01-19 |
2019-07-25 |
President And Fellows Of Harward College |
Gdf11 variants and uses thereof
|