JP2016510738A5 - - Google Patents
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- Publication number
- JP2016510738A5 JP2016510738A5 JP2015561314A JP2015561314A JP2016510738A5 JP 2016510738 A5 JP2016510738 A5 JP 2016510738A5 JP 2015561314 A JP2015561314 A JP 2015561314A JP 2015561314 A JP2015561314 A JP 2015561314A JP 2016510738 A5 JP2016510738 A5 JP 2016510738A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- item
- continuous infusion
- oral
- administration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000001802 infusion Methods 0.000 claims description 24
- 229960001080 cangrelor Drugs 0.000 claims description 23
- PAEBIVWUMLRPSK-IDTAVKCVSA-N cangrelor Chemical compound C1=NC=2C(NCCSC)=NC(SCCC(F)(F)F)=NC=2N1[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)C(Cl)(Cl)P(O)(O)=O)[C@@H](O)[C@H]1O PAEBIVWUMLRPSK-IDTAVKCVSA-N 0.000 claims description 23
- 229960002528 ticagrelor Drugs 0.000 claims description 17
- OEKWJQXRCDYSHL-FNOIDJSQSA-N ticagrelor Chemical compound C1([C@@H]2C[C@H]2NC=2N=C(N=C3N([C@H]4[C@@H]([C@H](O)[C@@H](OCCO)C4)O)N=NC3=2)SCCC)=CC=C(F)C(F)=C1 OEKWJQXRCDYSHL-FNOIDJSQSA-N 0.000 claims description 17
- 238000013146 percutaneous coronary intervention Methods 0.000 claims description 13
- 239000005552 B01AC04 - Clopidogrel Substances 0.000 claims description 5
- 239000005465 B01AC22 - Prasugrel Substances 0.000 claims description 5
- 229960003009 clopidogrel Drugs 0.000 claims description 5
- GKTWGGQPFAXNFI-HNNXBMFYSA-N clopidogrel Chemical compound C1([C@H](N2CC=3C=CSC=3CC2)C(=O)OC)=CC=CC=C1Cl GKTWGGQPFAXNFI-HNNXBMFYSA-N 0.000 claims description 5
- 229960004197 prasugrel Drugs 0.000 claims description 5
- DTGLZDAWLRGWQN-UHFFFAOYSA-N prasugrel Chemical compound C1CC=2SC(OC(=O)C)=CC=2CN1C(C=1C(=CC=CC=1)F)C(=O)C1CC1 DTGLZDAWLRGWQN-UHFFFAOYSA-N 0.000 claims description 5
- 238000011282 treatment Methods 0.000 claims description 5
- 239000008355 dextrose injection Substances 0.000 claims description 4
- 239000008354 sodium chloride injection Substances 0.000 claims description 4
- 239000000203 mixture Substances 0.000 claims 15
- 238000001356 surgical procedure Methods 0.000 claims 4
- 239000003112 inhibitor Substances 0.000 claims 2
- 230000005764 inhibitory process Effects 0.000 claims 2
- 239000007924 injection Substances 0.000 claims 2
- 238000002347 injection Methods 0.000 claims 2
- NXAYYSHEARRBLR-UHFFFAOYSA-N 7-(3,5-diethyl-1-methylpyrazol-4-yl)-1-(2-morpholin-4-ylethyl)-3-(3-naphthalen-1-yloxypropyl)indole-2-carboxylic acid Chemical compound CCc1nn(C)c(CC)c1-c1cccc2c(CCCOc3cccc4ccccc34)c(C(O)=O)n(CCN3CCOCC3)c12 NXAYYSHEARRBLR-UHFFFAOYSA-N 0.000 claims 1
- 239000002172 P2Y12 inhibitor Substances 0.000 claims 1
- 210000004351 coronary vessel Anatomy 0.000 claims 1
- 238000000034 method Methods 0.000 description 36
- 239000008194 pharmaceutical composition Substances 0.000 description 9
- 238000001990 intravenous administration Methods 0.000 description 6
- 230000000694 effects Effects 0.000 description 3
- 230000000977 initiatory effect Effects 0.000 description 3
- 238000011866 long-term treatment Methods 0.000 description 3
- 238000002560 therapeutic procedure Methods 0.000 description 3
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 description 1
- 229960001138 acetylsalicylic acid Drugs 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/792,056 | 2013-03-09 | ||
| US13/792,056 US9427448B2 (en) | 2009-11-11 | 2013-03-09 | Methods of treating, reducing the incidence of, and/or preventing ischemic events |
| US201361815735P | 2013-04-25 | 2013-04-25 | |
| US61/815,735 | 2013-04-25 | ||
| PCT/US2013/043136 WO2014143107A1 (en) | 2013-03-09 | 2013-05-29 | Methods of treating, reducing the incidence of, and/or preventing ischemic events |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017197488A Division JP2018002739A (ja) | 2013-03-09 | 2017-10-11 | 虚血性事象を処置し、その発生率を低減させ、かつ／または予防する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016510738A JP2016510738A (ja) | 2016-04-11 |
| JP2016510738A5 true JP2016510738A5 (enExample) | 2016-07-14 |
| JP6247708B2 JP6247708B2 (ja) | 2017-12-13 |
Family
ID=51537409
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015561314A Active JP6247708B2 (ja) | 2013-03-09 | 2013-05-29 | 虚血性事象を処置し、その発生率を低減させ、かつ／または予防する方法 |
| JP2017197488A Withdrawn JP2018002739A (ja) | 2013-03-09 | 2017-10-11 | 虚血性事象を処置し、その発生率を低減させ、かつ／または予防する方法 |
| JP2019137721A Active JP6840197B2 (ja) | 2013-03-09 | 2019-07-26 | 虚血性事象を処置し、その発生率を低減させ、かつ／または予防する方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017197488A Withdrawn JP2018002739A (ja) | 2013-03-09 | 2017-10-11 | 虚血性事象を処置し、その発生率を低減させ、かつ／または予防する方法 |
| JP2019137721A Active JP6840197B2 (ja) | 2013-03-09 | 2019-07-26 | 虚血性事象を処置し、その発生率を低減させ、かつ／または予防する方法 |
Country Status (10)
| Country | Link |
|---|---|
| EP (2) | EP2964233B1 (enExample) |
| JP (3) | JP6247708B2 (enExample) |
| CN (2) | CN115120606A (enExample) |
| AU (1) | AU2013381855B2 (enExample) |
| BR (1) | BR112015022070B1 (enExample) |
| CA (1) | CA2904523C (enExample) |
| EA (1) | EA034550B1 (enExample) |
| ES (1) | ES2904256T3 (enExample) |
| PL (1) | PL2964233T3 (enExample) |
| WO (1) | WO2014143107A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2013381855B2 (en) * | 2013-03-09 | 2018-08-02 | Chiesi Farmaceutici S.P.A. | Methods of treating, reducing the incidence of, and/or preventing ischemic events |
| WO2018234565A1 (en) | 2017-06-23 | 2018-12-27 | Chiesi Farmaceutici S.P.A. | METHOD FOR PREVENTING SHUNT THROMBOSIS FROM THE SYSTEMIC-PULMONARY ARTERY |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SK281309B6 (sk) | 1993-02-10 | 2001-02-12 | Astra Pharmaceuticals Limited | N-alkyl-2-substituované adenozíntrifosfátové deriváty, spôsob ich prípravy, farmaceutické prostriedky obsahujúce tieto deriváty a použitie týchto derivátov |
| ID21635A (id) | 1996-12-20 | 1999-07-08 | Astra Pharma Prod | Komposisi farmasi untuk pengeringan beku |
| SE9702680D0 (sv) | 1997-07-11 | 1997-07-11 | Astra Pharma Prod | New formulation |
| SE9904377D0 (sv) | 1999-12-01 | 1999-12-01 | Astra Pharma Prod | Pharmaceutical combinations |
| WO2009140092A1 (en) * | 2008-05-13 | 2009-11-19 | The Medicines Company | Maintenance of platelet inhibition during antiplatelet therapy |
| US9427448B2 (en) * | 2009-11-11 | 2016-08-30 | The Medicines Company | Methods of treating, reducing the incidence of, and/or preventing ischemic events |
| US20100297675A1 (en) * | 2008-11-24 | 2010-11-25 | Huayun Deng | Substrate and method for culturing breast cells |
| JP5851246B2 (ja) * | 2008-12-30 | 2016-02-03 | リグスホスピタルＲｉｇｓｈｏｓｐｉｔａｌｅｔ | 臓器不全の発生リスクが上昇した重篤患者を識別する方法およびその治療のための化合物 |
| PT2443120T (pt) * | 2009-06-16 | 2017-02-08 | Rspr Pharma Ab | Forma cristalina de pemirolast |
| BR112012011298B1 (pt) * | 2009-11-11 | 2021-12-14 | Chiesi Farmaceutici S.P.A. | Uso de cangrelor e/ou bivalirudina na preparação de medicamentos e combinação de medicamentos |
| AU2013381855B2 (en) * | 2013-03-09 | 2018-08-02 | Chiesi Farmaceutici S.P.A. | Methods of treating, reducing the incidence of, and/or preventing ischemic events |
-
2013
- 2013-05-29 AU AU2013381855A patent/AU2013381855B2/en active Active
- 2013-05-29 WO PCT/US2013/043136 patent/WO2014143107A1/en not_active Ceased
- 2013-05-29 EP EP13878203.2A patent/EP2964233B1/en active Active
- 2013-05-29 CN CN202210682855.1A patent/CN115120606A/zh active Pending
- 2013-05-29 CN CN201380076382.XA patent/CN106102750A/zh active Pending
- 2013-05-29 EP EP21205348.2A patent/EP3978002A1/en active Pending
- 2013-05-29 ES ES13878203T patent/ES2904256T3/es active Active
- 2013-05-29 CA CA2904523A patent/CA2904523C/en active Active
- 2013-05-29 JP JP2015561314A patent/JP6247708B2/ja active Active
- 2013-05-29 PL PL13878203T patent/PL2964233T3/pl unknown
- 2013-05-29 EA EA201591683A patent/EA034550B1/ru unknown
- 2013-05-29 BR BR112015022070-3A patent/BR112015022070B1/pt active IP Right Grant
-
2017
- 2017-10-11 JP JP2017197488A patent/JP2018002739A/ja not_active Withdrawn
-
2019
- 2019-07-26 JP JP2019137721A patent/JP6840197B2/ja active Active