JP2019501145A5 - - Google Patents
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- Publication number
- JP2019501145A5 JP2019501145A5 JP2018528650A JP2018528650A JP2019501145A5 JP 2019501145 A5 JP2019501145 A5 JP 2019501145A5 JP 2018528650 A JP2018528650 A JP 2018528650A JP 2018528650 A JP2018528650 A JP 2018528650A JP 2019501145 A5 JP2019501145 A5 JP 2019501145A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- cancer
- composition according
- checkpoint inhibitor
- fucose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562263228P | 2015-12-04 | 2015-12-04 | |
| US62/263,228 | 2015-12-04 | ||
| US201662308583P | 2016-03-15 | 2016-03-15 | |
| US62/308,583 | 2016-03-15 | ||
| US201662321857P | 2016-04-13 | 2016-04-13 | |
| US62/321,857 | 2016-04-13 | ||
| PCT/US2016/064783 WO2017096274A1 (en) | 2015-12-04 | 2016-12-02 | Cancer treatment using 2-deoxy-2-fluoro-l-fucose in combination with a checkpoint inhibitor |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019501145A JP2019501145A (ja) | 2019-01-17 |
| JP2019501145A5 true JP2019501145A5 (cg-RX-API-DMAC7.html) | 2020-01-16 |
| JP6906520B2 JP6906520B2 (ja) | 2021-07-21 |
Family
ID=58797961
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018528650A Active JP6906520B2 (ja) | 2015-12-04 | 2016-12-02 | チェックポイント阻害剤と組みわせて２−デオキシ−２−フルオロ−ｌ−フコースを用いる癌治療 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20180353524A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3383404A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6906520B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20180086233A (cg-RX-API-DMAC7.html) |
| CN (1) | CN108289903B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2016362993A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112018011261A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3005997A1 (cg-RX-API-DMAC7.html) |
| EA (1) | EA201891340A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL259479B (cg-RX-API-DMAC7.html) |
| MX (1) | MX385283B (cg-RX-API-DMAC7.html) |
| SG (2) | SG11201804263PA (cg-RX-API-DMAC7.html) |
| WO (1) | WO2017096274A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9504702B2 (en) | 2010-08-05 | 2016-11-29 | Seattle Genetics, Inc. | Methods of inhibition of protein fucosylation in vivo using fucose analogs |
| WO2018071500A1 (en) | 2016-10-11 | 2018-04-19 | Agenus Inc. | Anti-lag-3 antibodies and methods of use thereof |
| JP7245177B2 (ja) * | 2017-06-07 | 2023-03-23 | シージェン インコーポレイテッド | 低減した表面フコシル化を有するｔ細胞、及びそれを作製及び使用する方法 |
| WO2019075449A1 (en) * | 2017-10-13 | 2019-04-18 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | FUCOSYLATION AND IMMUNOSURVEILLANCE OF MELANOMA |
| US11401339B2 (en) | 2018-08-23 | 2022-08-02 | Seagen Inc. | Anti-TIGIT antibodies |
| CA3123591A1 (en) * | 2018-12-19 | 2020-06-25 | Seagen Inc. | Controlled fucosylation of antibodies |
| WO2021034774A1 (en) * | 2019-08-16 | 2021-02-25 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Fucosylation and immune modulation in cancer |
| CN111973749B (zh) * | 2020-09-07 | 2023-03-21 | 威海人生药业集团股份有限公司 | 一种抗肿瘤免疫治疗的药物组合物 |
| WO2022198231A1 (en) | 2021-03-18 | 2022-09-22 | Seagen Inc. | Selective drug release from internalized conjugates of biologically active compounds |
| WO2022221766A1 (en) * | 2021-04-16 | 2022-10-20 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Fucosylation and immune modulation in cancer |
| CN113274502B (zh) * | 2021-05-05 | 2023-01-03 | 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） | 用于特定型三阴乳腺癌免疫治疗的组合物 |
| WO2022236017A1 (en) * | 2021-05-06 | 2022-11-10 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | L-fucose and anti-androgen receptor therapy for treatment of cancer |
| CN113413465B (zh) * | 2021-06-15 | 2022-06-03 | 北京大学 | 岩藻糖基化抑制剂在抗癌导致炎症中的应用 |
| CN115466297B (zh) * | 2022-08-25 | 2023-07-07 | 青岛农业大学 | L-岩藻糖的应用以及动物饲料 |
| WO2024077106A2 (en) * | 2022-10-04 | 2024-04-11 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Leveraging l-fucose-mediated signaling to induce monocyte-derived dendritic cell polarization |
| WO2024191807A1 (en) | 2023-03-10 | 2024-09-19 | Seagen Inc. | Methods of treating cancer with anti-tigit antibodies |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9504702B2 (en) * | 2010-08-05 | 2016-11-29 | Seattle Genetics, Inc. | Methods of inhibition of protein fucosylation in vivo using fucose analogs |
| EP3065772B1 (en) | 2013-11-05 | 2024-07-24 | Cognate Bioservices, Inc. | Combinations of checkpoint inhibitors and therapeutics to treat cancer |
-
2016
- 2016-12-02 JP JP2018528650A patent/JP6906520B2/ja active Active
- 2016-12-02 AU AU2016362993A patent/AU2016362993A1/en not_active Abandoned
- 2016-12-02 MX MX2018006674A patent/MX385283B/es unknown
- 2016-12-02 BR BR112018011261A patent/BR112018011261A2/pt not_active Application Discontinuation
- 2016-12-02 SG SG11201804263PA patent/SG11201804263PA/en unknown
- 2016-12-02 SG SG10202005298RA patent/SG10202005298RA/en unknown
- 2016-12-02 CA CA3005997A patent/CA3005997A1/en not_active Abandoned
- 2016-12-02 EP EP16871645.4A patent/EP3383404A4/en not_active Withdrawn
- 2016-12-02 EA EA201891340A patent/EA201891340A1/ru unknown
- 2016-12-02 CN CN201680071076.0A patent/CN108289903B/zh not_active Expired - Fee Related
- 2016-12-02 KR KR1020187017824A patent/KR20180086233A/ko not_active Withdrawn
- 2016-12-02 US US15/781,256 patent/US20180353524A1/en not_active Abandoned
- 2016-12-02 WO PCT/US2016/064783 patent/WO2017096274A1/en not_active Ceased
-
2018
- 2018-05-21 IL IL259479A patent/IL259479B/en unknown
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