JP2019500582A5 - - Google Patents
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- JP2019500582A5 JP2019500582A5 JP2018520599A JP2018520599A JP2019500582A5 JP 2019500582 A5 JP2019500582 A5 JP 2019500582A5 JP 2018520599 A JP2018520599 A JP 2018520599A JP 2018520599 A JP2018520599 A JP 2018520599A JP 2019500582 A5 JP2019500582 A5 JP 2019500582A5
- Authority
- JP
- Japan
- Prior art keywords
- configuration
- histone
- cancer
- binding agent
- epitope
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1518665.3 | 2015-10-21 | ||
| GBGB1518665.3A GB201518665D0 (en) | 2015-10-21 | 2015-10-21 | Method for enrichment of cell free nucleosomes |
| PCT/GB2016/053305 WO2017068371A1 (en) | 2015-10-21 | 2016-10-21 | Method for the enrichment of cell free nucleosomes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019500582A JP2019500582A (ja) | 2019-01-10 |
| JP2019500582A5 true JP2019500582A5 (enExample) | 2019-11-14 |
| JP6831841B2 JP6831841B2 (ja) | 2021-02-17 |
Family
ID=55131411
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018520599A Expired - Fee Related JP6831841B2 (ja) | 2015-10-21 | 2016-10-21 | 無細胞ヌクレオソームの濃縮のための方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10746746B2 (enExample) |
| EP (2) | EP3365684B1 (enExample) |
| JP (1) | JP6831841B2 (enExample) |
| CN (1) | CN108603884A (enExample) |
| AU (1) | AU2016341501B2 (enExample) |
| CA (1) | CA3002505A1 (enExample) |
| DK (1) | DK3365684T3 (enExample) |
| ES (1) | ES2830800T3 (enExample) |
| GB (1) | GB201518665D0 (enExample) |
| PL (1) | PL3365684T3 (enExample) |
| SG (1) | SG11201803161YA (enExample) |
| WO (1) | WO2017068371A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HK1206055A1 (en) | 2012-03-02 | 2015-12-31 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| EP2971100A1 (en) | 2013-03-13 | 2016-01-20 | Sequenom, Inc. | Primers for dna methylation analysis |
| EP3736344A1 (en) | 2014-03-13 | 2020-11-11 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| PL3685165T3 (pl) * | 2017-09-18 | 2022-08-08 | Santersus Ag | Sposób i urządzenie do oczyszczania krwi z krążącego pozakomórkowego dna |
| EP4215621B1 (en) | 2018-03-01 | 2025-05-28 | Epicypher, Inc. | Quantification of nucleosome modifications using chemically-defined recombinant nucleosomes |
| EP3765638A2 (en) | 2018-03-13 | 2021-01-20 | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. | Diagnostic use of cell free dna chromatin immunoprecipitation |
| CN109841265B (zh) * | 2019-02-22 | 2021-09-21 | 清华大学 | 使用片段化模式确定血浆游离核酸分子组织来源的方法和系统及应用 |
| GB201906199D0 (en) * | 2019-05-02 | 2019-06-19 | Belgian Volition Sprl | Method for the detection of cancer |
| EP3757227A1 (en) * | 2019-06-25 | 2020-12-30 | Aarhus Universitet | Cell-free chromatin immunoprecipitation (cfchip) as a measure of tumour gene expression in a sample |
| GB201912251D0 (en) | 2019-08-27 | 2019-10-09 | Belgian Volition Sprl | Method of isolating circulating nucleosomes |
| US20220290252A1 (en) * | 2019-08-27 | 2022-09-15 | Belgian Volition Srl | Method of isolating circulating nucleosomes |
| CN114829939B (zh) * | 2019-12-02 | 2025-10-21 | 比利时意志有限责任公司 | 无细胞核小体作为生物标志物的用途 |
| TW202242145A (zh) * | 2020-12-29 | 2022-11-01 | 比利時商比利時意志有限公司 | 核小體耗盡循環無細胞染色質片段之轉錄因子結合位點分析 |
| US12053567B2 (en) | 2021-12-27 | 2024-08-06 | Santersus Ag | Method and device for removal of circulating cell free DNA |
| WO2024042210A1 (en) * | 2022-08-25 | 2024-02-29 | Belgian Volition Srl | Method for measuring cell free chromatin |
| GB202300607D0 (en) | 2023-01-16 | 2023-03-01 | Belgian Volition Srl | Proteins and methods for isolating circulating nucleosomes |
| TW202530419A (zh) | 2023-10-04 | 2025-08-01 | 比利時商比利時意志有限公司 | Pcr方法 |
| CN117904196B (zh) * | 2024-01-05 | 2024-07-12 | 安徽大学 | 一种非小细胞肺癌组蛋白h1.4赖氨酸乙酰化点突变细胞模型的构建及其应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5807999A (en) | 1993-02-01 | 1998-09-15 | Mt. Sinai School Of Medicine Of The City University Of New York | Monoclonal antibody that distinguishes between phosphorylated and nonphosphorylated histone H1 and uses therefor |
| GB0319376D0 (en) * | 2003-08-18 | 2003-09-17 | Chroma Therapeutics Ltd | Histone modification detection |
| EP2496717B1 (en) | 2009-11-05 | 2017-06-07 | The Chinese University of Hong Kong | Fetal genomic analysis from a maternal biological sample |
| WO2011092715A2 (en) | 2010-01-27 | 2011-08-04 | Tata Memorial Centre | Method for in-vivo binding of chromatin fragments |
| US8981066B2 (en) | 2011-08-23 | 2015-03-17 | Buck Institute For Research On Aging | Epigenetic mechanisms related to DNA damage and aging |
| GB201115098D0 (en) | 2011-09-01 | 2011-10-19 | Belgian Volition Sa | Method for detecting nucleosomes containing histone variants |
| GB201115099D0 (en) * | 2011-09-01 | 2011-10-19 | Belgian Volition Sa | Method for detecting nucleosomes |
| GB201115095D0 (en) | 2011-09-01 | 2011-10-19 | Singapore Volition Pte Ltd | Method for detecting nucleosomes containing nucleotides |
| EP2788767B1 (en) | 2011-12-07 | 2017-09-06 | Belgian Volition SPRL | Method for detecting nucleosome adducts |
| HK1206055A1 (en) * | 2012-03-02 | 2015-12-31 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
-
2015
- 2015-10-21 GB GBGB1518665.3A patent/GB201518665D0/en not_active Ceased
-
2016
- 2016-10-21 WO PCT/GB2016/053305 patent/WO2017068371A1/en not_active Ceased
- 2016-10-21 EP EP16787545.9A patent/EP3365684B1/en active Active
- 2016-10-21 US US15/768,984 patent/US10746746B2/en active Active
- 2016-10-21 CA CA3002505A patent/CA3002505A1/en active Pending
- 2016-10-21 JP JP2018520599A patent/JP6831841B2/ja not_active Expired - Fee Related
- 2016-10-21 AU AU2016341501A patent/AU2016341501B2/en not_active Ceased
- 2016-10-21 SG SG11201803161YA patent/SG11201803161YA/en unknown
- 2016-10-21 PL PL16787545T patent/PL3365684T3/pl unknown
- 2016-10-21 CN CN201680074815.1A patent/CN108603884A/zh active Pending
- 2016-10-21 EP EP20190999.1A patent/EP3798634A1/en not_active Withdrawn
- 2016-10-21 DK DK16787545.9T patent/DK3365684T3/da active
- 2016-10-21 ES ES16787545T patent/ES2830800T3/es active Active
-
2020
- 2020-07-14 US US16/929,016 patent/US20200340997A1/en not_active Abandoned
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