PL3365684T3 - Sposób wzbogacania nukleosomów pozakomórkowych - Google Patents
Sposób wzbogacania nukleosomów pozakomórkowychInfo
- Publication number
- PL3365684T3 PL3365684T3 PL16787545T PL16787545T PL3365684T3 PL 3365684 T3 PL3365684 T3 PL 3365684T3 PL 16787545 T PL16787545 T PL 16787545T PL 16787545 T PL16787545 T PL 16787545T PL 3365684 T3 PL3365684 T3 PL 3365684T3
- Authority
- PL
- Poland
- Prior art keywords
- nucleosomes
- enriching extracellular
- enriching
- extracellular
- extracellular nucleosomes
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6875—Nucleoproteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
- G01N33/57585—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2440/00—Post-translational modifications [PTMs] in chemical analysis of biological material
- G01N2440/12—Post-translational modifications [PTMs] in chemical analysis of biological material alkylation, e.g. methylation, (iso-)prenylation, farnesylation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Oncology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1518665.3A GB201518665D0 (en) | 2015-10-21 | 2015-10-21 | Method for enrichment of cell free nucleosomes |
| PCT/GB2016/053305 WO2017068371A1 (en) | 2015-10-21 | 2016-10-21 | Method for the enrichment of cell free nucleosomes |
| EP16787545.9A EP3365684B1 (en) | 2015-10-21 | 2016-10-21 | Method for the enrichment of cell free nucleosomes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3365684T3 true PL3365684T3 (pl) | 2021-05-04 |
Family
ID=55131411
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL16787545T PL3365684T3 (pl) | 2015-10-21 | 2016-10-21 | Sposób wzbogacania nukleosomów pozakomórkowych |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10746746B2 (pl) |
| EP (2) | EP3798634A1 (pl) |
| JP (1) | JP6831841B2 (pl) |
| CN (1) | CN108603884A (pl) |
| AU (1) | AU2016341501B2 (pl) |
| CA (1) | CA3002505A1 (pl) |
| DK (1) | DK3365684T3 (pl) |
| ES (1) | ES2830800T3 (pl) |
| GB (1) | GB201518665D0 (pl) |
| PL (1) | PL3365684T3 (pl) |
| SG (1) | SG11201803161YA (pl) |
| WO (1) | WO2017068371A1 (pl) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HK1206055A1 (en) | 2012-03-02 | 2015-12-31 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| HK1216655A1 (zh) | 2013-03-13 | 2016-11-25 | Sequenom, Inc. | 用於dna甲基化分析的引物 |
| US11365447B2 (en) | 2014-03-13 | 2022-06-21 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| ES2913665T3 (es) * | 2017-09-18 | 2022-06-03 | Santersus Ag | Método y dispositivo para la purificación de sangre a partir de ADN celular libre en circulación |
| AU2019228625B2 (en) | 2018-03-01 | 2024-11-07 | Epicypher, Inc. | Quantification of nucleosome modifications using chemically-defined recombinant nucleosomes |
| CN112119166B (zh) * | 2018-03-13 | 2025-08-22 | 耶路撒冷希伯来大学伊萨姆研发有限公司 | 无细胞dna染色质免疫沉淀的诊断应用 |
| CN109841265B (zh) * | 2019-02-22 | 2021-09-21 | 清华大学 | 使用片段化模式确定血浆游离核酸分子组织来源的方法和系统及应用 |
| GB201906199D0 (en) * | 2019-05-02 | 2019-06-19 | Belgian Volition Sprl | Method for the detection of cancer |
| EP3757227A1 (en) * | 2019-06-25 | 2020-12-30 | Aarhus Universitet | Cell-free chromatin immunoprecipitation (cfchip) as a measure of tumour gene expression in a sample |
| JP2022545821A (ja) * | 2019-08-27 | 2022-10-31 | ベルジアン ボリション エスアールエル | 循環ヌクレオソームを単離する方法 |
| GB201912251D0 (en) | 2019-08-27 | 2019-10-09 | Belgian Volition Sprl | Method of isolating circulating nucleosomes |
| PL4070111T3 (pl) * | 2019-12-02 | 2025-02-03 | Belgian Volition Srl | Zastosowanie wolnych pozakomórkowych nukleosomsów jako biomarkerów |
| TW202242145A (zh) * | 2020-12-29 | 2022-11-01 | 比利時商比利時意志有限公司 | 核小體耗盡循環無細胞染色質片段之轉錄因子結合位點分析 |
| WO2023126672A1 (en) | 2021-12-27 | 2023-07-06 | Santersus Ag | Method and device for removal of circulating cell free dna |
| WO2024042210A1 (en) * | 2022-08-25 | 2024-02-29 | Belgian Volition Srl | Method for measuring cell free chromatin |
| GB202300607D0 (en) | 2023-01-16 | 2023-03-01 | Belgian Volition Srl | Proteins and methods for isolating circulating nucleosomes |
| WO2025073909A1 (en) | 2023-10-04 | 2025-04-10 | Belgian Volition Srl | Pcr method for detecting ctcf occupied cfdna fragments |
| CN117904196B (zh) * | 2024-01-05 | 2024-07-12 | 安徽大学 | 一种非小细胞肺癌组蛋白h1.4赖氨酸乙酰化点突变细胞模型的构建及其应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5807999A (en) | 1993-02-01 | 1998-09-15 | Mt. Sinai School Of Medicine Of The City University Of New York | Monoclonal antibody that distinguishes between phosphorylated and nonphosphorylated histone H1 and uses therefor |
| GB0319376D0 (en) | 2003-08-18 | 2003-09-17 | Chroma Therapeutics Ltd | Histone modification detection |
| LT3783110T (lt) | 2009-11-05 | 2023-01-25 | The Chinese University Of Hong Kong | Vaisiaus genomo analizė iš motinos biologinio mėginio |
| US9096655B2 (en) | 2010-01-27 | 2015-08-04 | Tata Memorial Centre | Method for in-vivo binding of chromatin fragments |
| US8981066B2 (en) | 2011-08-23 | 2015-03-17 | Buck Institute For Research On Aging | Epigenetic mechanisms related to DNA damage and aging |
| GB201115099D0 (en) * | 2011-09-01 | 2011-10-19 | Belgian Volition Sa | Method for detecting nucleosomes |
| GB201115095D0 (en) * | 2011-09-01 | 2011-10-19 | Singapore Volition Pte Ltd | Method for detecting nucleosomes containing nucleotides |
| GB201115098D0 (en) | 2011-09-01 | 2011-10-19 | Belgian Volition Sa | Method for detecting nucleosomes containing histone variants |
| CN104067125B (zh) * | 2011-12-07 | 2017-12-26 | 比利时意志有限责任公司 | 用于检测核小体加合物的方法 |
| HK1206055A1 (en) * | 2012-03-02 | 2015-12-31 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
-
2015
- 2015-10-21 GB GBGB1518665.3A patent/GB201518665D0/en not_active Ceased
-
2016
- 2016-10-21 EP EP20190999.1A patent/EP3798634A1/en not_active Withdrawn
- 2016-10-21 EP EP16787545.9A patent/EP3365684B1/en active Active
- 2016-10-21 WO PCT/GB2016/053305 patent/WO2017068371A1/en not_active Ceased
- 2016-10-21 CA CA3002505A patent/CA3002505A1/en active Pending
- 2016-10-21 AU AU2016341501A patent/AU2016341501B2/en not_active Ceased
- 2016-10-21 ES ES16787545T patent/ES2830800T3/es active Active
- 2016-10-21 US US15/768,984 patent/US10746746B2/en active Active
- 2016-10-21 DK DK16787545.9T patent/DK3365684T3/da active
- 2016-10-21 SG SG11201803161YA patent/SG11201803161YA/en unknown
- 2016-10-21 PL PL16787545T patent/PL3365684T3/pl unknown
- 2016-10-21 JP JP2018520599A patent/JP6831841B2/ja not_active Expired - Fee Related
- 2016-10-21 CN CN201680074815.1A patent/CN108603884A/zh active Pending
-
2020
- 2020-07-14 US US16/929,016 patent/US20200340997A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20200340997A1 (en) | 2020-10-29 |
| US20190064184A1 (en) | 2019-02-28 |
| EP3798634A1 (en) | 2021-03-31 |
| DK3365684T3 (da) | 2020-12-21 |
| EP3365684B1 (en) | 2020-09-23 |
| SG11201803161YA (en) | 2018-05-30 |
| AU2016341501B2 (en) | 2022-09-08 |
| WO2017068371A1 (en) | 2017-04-27 |
| ES2830800T3 (es) | 2021-06-04 |
| AU2016341501A1 (en) | 2018-05-10 |
| EP3365684A1 (en) | 2018-08-29 |
| GB201518665D0 (en) | 2015-12-02 |
| CN108603884A (zh) | 2018-09-28 |
| JP6831841B2 (ja) | 2021-02-17 |
| US10746746B2 (en) | 2020-08-18 |
| JP2019500582A (ja) | 2019-01-10 |
| CA3002505A1 (en) | 2017-04-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PL3365684T3 (pl) | Sposób wzbogacania nukleosomów pozakomórkowych | |
| IL249981A0 (en) | Method | |
| PL3092124T3 (pl) | Sposób wytwarzania fornirowanego elementu | |
| PL3325443T3 (pl) | Sposób otrzymywania pridopidyny | |
| LT3137169T (lt) | Lizinui specifinės demetilazės-1 inhibitoriai | |
| IL245356A0 (en) | Method and system of automated generation of user form interface | |
| LT3160956T (lt) | Lizinui specifinės demetilazės-1 inhibitoriai | |
| LT3164380T (lt) | Lizinui specifiniai demetilazės-1 inhibitoriai | |
| EP3287793A4 (en) | AUTO ANALYZER AND METHOD | |
| DK3132009T3 (da) | Fremgangsmåde | |
| IL248785A0 (en) | Carboxamide derivatives | |
| EP3368921A4 (en) | MODIFICATION OF AN INTERACTIVE SALT MODEL | |
| PL3169844T3 (pl) | Sposób zapobiegania tworzeniu się kamienia kotłowego | |
| IL252086A0 (en) | Novel methods | |
| PL3131549T3 (pl) | Sposób leczenia zaburzeń ruchowych przy użyciu befiradolu | |
| IL248739B (en) | Method of displaying images | |
| LT3152325T (lt) | Trišakės neuralgijos diagnostikos būdas | |
| PL3161136T3 (pl) | Sposób wzbogacania mikropęcherzyków | |
| LT3253772T (lt) | Diosmino ruošimo būdas | |
| PL3180295T3 (pl) | Sposób szybkiej humifikacji i biostabilizacji | |
| IL254336A0 (en) | Novel treatment method | |
| PL3410868T3 (pl) | Sposób wytwarzania samoemulgującej kompozycji tłuszczowej | |
| PL3283552T3 (pl) | Sposób acetylacji ciągłej elementów drewnianych | |
| DK3280699T3 (da) | Fremgangsmåde til fremstilling af acylsulfamoylbenzamider | |
| DK3053446T3 (da) | Fremgangsmåde til fremstilling af schweizerost |