SG11201803161YA - Method for the enrichment of cell free nucleosomes - Google Patents
Method for the enrichment of cell free nucleosomesInfo
- Publication number
- SG11201803161YA SG11201803161YA SG11201803161YA SG11201803161YA SG11201803161YA SG 11201803161Y A SG11201803161Y A SG 11201803161YA SG 11201803161Y A SG11201803161Y A SG 11201803161YA SG 11201803161Y A SG11201803161Y A SG 11201803161YA SG 11201803161Y A SG11201803161Y A SG 11201803161YA
- Authority
- SG
- Singapore
- Prior art keywords
- enrichment
- cell free
- free nucleosomes
- nucleosomes
- cell
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6875—Nucleoproteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2440/00—Post-translational modifications [PTMs] in chemical analysis of biological material
- G01N2440/12—Post-translational modifications [PTMs] in chemical analysis of biological material alkylation, e.g. methylation, (iso-)prenylation, farnesylation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Food Science & Technology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1518665.3A GB201518665D0 (en) | 2015-10-21 | 2015-10-21 | Method for enrichment of cell free nucleosomes |
| PCT/GB2016/053305 WO2017068371A1 (en) | 2015-10-21 | 2016-10-21 | Method for the enrichment of cell free nucleosomes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201803161YA true SG11201803161YA (en) | 2018-05-30 |
Family
ID=55131411
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201803161YA SG11201803161YA (en) | 2015-10-21 | 2016-10-21 | Method for the enrichment of cell free nucleosomes |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10746746B2 (en) |
| EP (2) | EP3798634A1 (en) |
| JP (1) | JP6831841B2 (en) |
| CN (1) | CN108603884A (en) |
| AU (1) | AU2016341501B2 (en) |
| CA (1) | CA3002505A1 (en) |
| DK (1) | DK3365684T3 (en) |
| ES (1) | ES2830800T3 (en) |
| GB (1) | GB201518665D0 (en) |
| PL (1) | PL3365684T3 (en) |
| SG (1) | SG11201803161YA (en) |
| WO (1) | WO2017068371A1 (en) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9605313B2 (en) | 2012-03-02 | 2017-03-28 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| EP3597774A1 (en) | 2013-03-13 | 2020-01-22 | Sequenom, Inc. | Primers for dna methylation analysis |
| EP3117011B1 (en) | 2014-03-13 | 2020-05-06 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| EP3978923A1 (en) * | 2017-09-18 | 2022-04-06 | Santersus AG | Method and device for purification of blood from circulating cell free dna |
| CN111918971A (en) * | 2018-03-01 | 2020-11-10 | 埃皮塞弗公司 | Quantification of nucleosome modification using chemically defined recombinant nucleosomes |
| EP3765638A2 (en) | 2018-03-13 | 2021-01-20 | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. | Diagnostic use of cell free dna chromatin immunoprecipitation |
| CN109841265B (en) * | 2019-02-22 | 2021-09-21 | 清华大学 | Method and system for determining tissue source of plasma free nucleic acid molecules by using fragmentation mode and application |
| EP3757227A1 (en) * | 2019-06-25 | 2020-12-30 | Aarhus Universitet | Cell-free chromatin immunoprecipitation (cfchip) as a measure of tumour gene expression in a sample |
| AU2020336928A1 (en) | 2019-08-27 | 2022-03-24 | Belgian Volition Srl | Method of isolating circulating nucleosomes |
| GB201912251D0 (en) | 2019-08-27 | 2019-10-09 | Belgian Volition Sprl | Method of isolating circulating nucleosomes |
| TW202242145A (en) * | 2020-12-29 | 2022-11-01 | 比利時商比利時意志有限公司 | Transcription factor binding site analysis of nucleosome depleted circulating cell free chromatin fragments |
| WO2024042210A1 (en) * | 2022-08-25 | 2024-02-29 | Belgian Volition Srl | Method for measuring cell free chromatin |
| CN117904196B (en) * | 2024-01-05 | 2024-07-12 | 安徽大学 | Construction and application of non-small cell lung cancer histone H1.4 lysine acetylation point mutation cell model |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5807999A (en) | 1993-02-01 | 1998-09-15 | Mt. Sinai School Of Medicine Of The City University Of New York | Monoclonal antibody that distinguishes between phosphorylated and nonphosphorylated histone H1 and uses therefor |
| GB0319376D0 (en) * | 2003-08-18 | 2003-09-17 | Chroma Therapeutics Ltd | Histone modification detection |
| CN102770558B (en) | 2009-11-05 | 2016-04-06 | 香港中文大学 | The analysis of Fetal genome is carried out by maternal biological sample |
| US9096655B2 (en) | 2010-01-27 | 2015-08-04 | Tata Memorial Centre | Method for in-vivo binding of chromatin fragments |
| US8981066B2 (en) | 2011-08-23 | 2015-03-17 | Buck Institute For Research On Aging | Epigenetic mechanisms related to DNA damage and aging |
| GB201115095D0 (en) * | 2011-09-01 | 2011-10-19 | Singapore Volition Pte Ltd | Method for detecting nucleosomes containing nucleotides |
| GB201115098D0 (en) | 2011-09-01 | 2011-10-19 | Belgian Volition Sa | Method for detecting nucleosomes containing histone variants |
| GB201115099D0 (en) * | 2011-09-01 | 2011-10-19 | Belgian Volition Sa | Method for detecting nucleosomes |
| CN104067125B (en) * | 2011-12-07 | 2017-12-26 | 比利时意志有限责任公司 | Method for detecting nucleosome adduct |
| US9605313B2 (en) | 2012-03-02 | 2017-03-28 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
-
2015
- 2015-10-21 GB GBGB1518665.3A patent/GB201518665D0/en not_active Ceased
-
2016
- 2016-10-21 JP JP2018520599A patent/JP6831841B2/en active Active
- 2016-10-21 AU AU2016341501A patent/AU2016341501B2/en not_active Ceased
- 2016-10-21 CN CN201680074815.1A patent/CN108603884A/en active Pending
- 2016-10-21 EP EP20190999.1A patent/EP3798634A1/en active Pending
- 2016-10-21 WO PCT/GB2016/053305 patent/WO2017068371A1/en active Application Filing
- 2016-10-21 DK DK16787545.9T patent/DK3365684T3/en active
- 2016-10-21 SG SG11201803161YA patent/SG11201803161YA/en unknown
- 2016-10-21 PL PL16787545T patent/PL3365684T3/en unknown
- 2016-10-21 ES ES16787545T patent/ES2830800T3/en active Active
- 2016-10-21 CA CA3002505A patent/CA3002505A1/en active Pending
- 2016-10-21 US US15/768,984 patent/US10746746B2/en active Active
- 2016-10-21 EP EP16787545.9A patent/EP3365684B1/en active Active
-
2020
- 2020-07-14 US US16/929,016 patent/US20200340997A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2016341501B2 (en) | 2022-09-08 |
| CN108603884A (en) | 2018-09-28 |
| PL3365684T3 (en) | 2021-05-04 |
| EP3365684A1 (en) | 2018-08-29 |
| JP6831841B2 (en) | 2021-02-17 |
| EP3798634A1 (en) | 2021-03-31 |
| AU2016341501A1 (en) | 2018-05-10 |
| JP2019500582A (en) | 2019-01-10 |
| EP3365684B1 (en) | 2020-09-23 |
| CA3002505A1 (en) | 2017-04-27 |
| US10746746B2 (en) | 2020-08-18 |
| WO2017068371A1 (en) | 2017-04-27 |
| GB201518665D0 (en) | 2015-12-02 |
| US20190064184A1 (en) | 2019-02-28 |
| US20200340997A1 (en) | 2020-10-29 |
| DK3365684T3 (en) | 2020-12-21 |
| ES2830800T3 (en) | 2021-06-04 |
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