JP2019172692A5 - - Google Patents
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- JP2019172692A5 JP2019172692A5 JP2019112474A JP2019112474A JP2019172692A5 JP 2019172692 A5 JP2019172692 A5 JP 2019172692A5 JP 2019112474 A JP2019112474 A JP 2019112474A JP 2019112474 A JP2019112474 A JP 2019112474A JP 2019172692 A5 JP2019172692 A5 JP 2019172692A5
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- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- extract
- acid
- prevention
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000008194 pharmaceutical composition Substances 0.000 claims 16
- -1 phenolic acid ester Chemical class 0.000 claims 6
- 235000013399 edible fruits Nutrition 0.000 claims 5
- 230000002265 prevention Effects 0.000 claims 5
- 208000010110 spontaneous platelet aggregation Diseases 0.000 claims 4
- 230000004087 circulation Effects 0.000 claims 3
- 208000010125 myocardial infarction Diseases 0.000 claims 3
- 150000007965 phenolic acids Chemical class 0.000 claims 3
- 208000005189 Embolism Diseases 0.000 claims 2
- NYHBQMYGNKIUIF-UUOKFMHZSA-N Guanosine Chemical compound C1=NC=2C(=O)NC(N)=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O NYHBQMYGNKIUIF-UUOKFMHZSA-N 0.000 claims 2
- 208000006011 Stroke Diseases 0.000 claims 2
- 208000001435 Thromboembolism Diseases 0.000 claims 2
- DRTQHJPVMGBUCF-XVFCMESISA-N Uridine Chemical compound O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-XVFCMESISA-N 0.000 claims 2
- OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 claims 2
- 230000017531 blood circulation Effects 0.000 claims 2
- 208000029078 coronary artery disease Diseases 0.000 claims 2
- 239000002552 dosage form Substances 0.000 claims 2
- 229930003935 flavonoid Natural products 0.000 claims 2
- 150000002215 flavonoids Chemical class 0.000 claims 2
- 235000017173 flavonoids Nutrition 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 239000002777 nucleoside Substances 0.000 claims 2
- 150000003833 nucleoside derivatives Chemical class 0.000 claims 2
- KSEBMYQBYZTDHS-HWKANZROSA-M (E)-Ferulic acid Natural products COC1=CC(\C=C\C([O-])=O)=CC=C1O KSEBMYQBYZTDHS-HWKANZROSA-M 0.000 claims 1
- WQSDYZZEIBAPIN-VBQORRLJSA-N 1-caffeoyl-beta-D-glucose Chemical group O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 WQSDYZZEIBAPIN-VBQORRLJSA-N 0.000 claims 1
- RQFCJASXJCIDSX-UHFFFAOYSA-N 14C-Guanosin-5'-monophosphat Natural products C1=2NC(N)=NC(=O)C=2N=CN1C1OC(COP(O)(O)=O)C(O)C1O RQFCJASXJCIDSX-UHFFFAOYSA-N 0.000 claims 1
- NGSWKAQJJWESNS-ZZXKWVIFSA-M 4-Hydroxycinnamate Natural products OC1=CC=C(\C=C\C([O-])=O)C=C1 NGSWKAQJJWESNS-ZZXKWVIFSA-M 0.000 claims 1
- OHEYCHKLBCPRLZ-VHCZEJTMSA-N 4-O-beta-D-glucosyl-trans-caffeic acid Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC=C(\C=C\C(O)=O)C=C1O OHEYCHKLBCPRLZ-VHCZEJTMSA-N 0.000 claims 1
- DFYRUELUNQRZTB-UHFFFAOYSA-N Acetovanillone Natural products COC1=CC(C(C)=O)=CC=C1O DFYRUELUNQRZTB-UHFFFAOYSA-N 0.000 claims 1
- 206010002388 Angina unstable Diseases 0.000 claims 1
- 201000001320 Atherosclerosis Diseases 0.000 claims 1
- JMGZEFIQIZZSBH-UHFFFAOYSA-N Bioquercetin Natural products CC1OC(OCC(O)C2OC(OC3=C(Oc4cc(O)cc(O)c4C3=O)c5ccc(O)c(O)c5)C(O)C2O)C(O)C(O)C1O JMGZEFIQIZZSBH-UHFFFAOYSA-N 0.000 claims 1
- 239000002126 C01EB10 - Adenosine Substances 0.000 claims 1
- MIKUYHXYGGJMLM-GIMIYPNGSA-N Crotonoside Natural products C1=NC2=C(N)NC(=O)N=C2N1[C@H]1O[C@@H](CO)[C@H](O)[C@@H]1O MIKUYHXYGGJMLM-GIMIYPNGSA-N 0.000 claims 1
- NYHBQMYGNKIUIF-UHFFFAOYSA-N D-guanosine Natural products C1=2NC(N)=NC(=O)C=2N=CN1C1OC(CO)C(O)C1O NYHBQMYGNKIUIF-UHFFFAOYSA-N 0.000 claims 1
- 206010051055 Deep vein thrombosis Diseases 0.000 claims 1
- 208000031226 Hyperlipidaemia Diseases 0.000 claims 1
- FVQOMEDMFUMIMO-UHFFFAOYSA-N Hyperosid Natural products OC1C(O)C(O)C(CO)OC1OC1C(=O)C2=C(O)C=C(O)C=C2OC1C1=CC=C(O)C(O)=C1 FVQOMEDMFUMIMO-UHFFFAOYSA-N 0.000 claims 1
- 208000022559 Inflammatory bowel disease Diseases 0.000 claims 1
- UPYKUZBSLRQECL-UKMVMLAPSA-N Lycopene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1C(=C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=C)CCCC2(C)C UPYKUZBSLRQECL-UKMVMLAPSA-N 0.000 claims 1
- 235000007688 Lycopersicon esculentum Nutrition 0.000 claims 1
- JEVVKJMRZMXFBT-XWDZUXABSA-N Lycophyll Natural products OC/C(=C/CC/C(=C\C=C\C(=C/C=C/C(=C\C=C\C=C(/C=C/C=C(\C=C\C=C(/CC/C=C(/CO)\C)\C)/C)\C)/C)\C)/C)/C JEVVKJMRZMXFBT-XWDZUXABSA-N 0.000 claims 1
- QJTYCCFDQWFJHU-UHFFFAOYSA-N Quercetin-5-O-beta-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1=CC(O)=CC2=C1C(=O)C(O)=C(C=1C=C(O)C(O)=CC=1)O2 QJTYCCFDQWFJHU-UHFFFAOYSA-N 0.000 claims 1
- 241000208292 Solanaceae Species 0.000 claims 1
- 240000003768 Solanum lycopersicum Species 0.000 claims 1
- 208000007814 Unstable Angina Diseases 0.000 claims 1
- 206010047249 Venous thrombosis Diseases 0.000 claims 1
- 239000013543 active substance Substances 0.000 claims 1
- 229960005305 adenosine Drugs 0.000 claims 1
- UDMBCSSLTHHNCD-KQYNXXCUSA-N adenosine 5'-monophosphate Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O UDMBCSSLTHHNCD-KQYNXXCUSA-N 0.000 claims 1
- 229950006790 adenosine phosphate Drugs 0.000 claims 1
- 238000002399 angioplasty Methods 0.000 claims 1
- 239000003146 anticoagulant agent Substances 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- DRTQHJPVMGBUCF-PSQAKQOGSA-N beta-L-uridine Natural products O[C@H]1[C@@H](O)[C@H](CO)O[C@@H]1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-PSQAKQOGSA-N 0.000 claims 1
- 230000000975 bioactive effect Effects 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 230000005189 cardiac health Effects 0.000 claims 1
- 210000000748 cardiovascular system Anatomy 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 150000001851 cinnamic acid derivatives Chemical group 0.000 claims 1
- NGSWKAQJJWESNS-UHFFFAOYSA-N cis-para-coumaric acid Natural products OC(=O)C=CC1=CC=C(O)C=C1 NGSWKAQJJWESNS-UHFFFAOYSA-N 0.000 claims 1
- 206010012601 diabetes mellitus Diseases 0.000 claims 1
- RAYJUFCFJUVJBB-UHFFFAOYSA-N dihydrokaempferol Natural products OC1Oc2c(O)cc(O)cc2C(=O)C1c3ccc(O)cc3 RAYJUFCFJUVJBB-UHFFFAOYSA-N 0.000 claims 1
- 150000002016 disaccharides Chemical class 0.000 claims 1
- IVTMALDHFAHOGL-UHFFFAOYSA-N eriodictyol 7-O-rutinoside Natural products OC1C(O)C(O)C(C)OC1OCC1C(O)C(O)C(O)C(OC=2C=C3C(C(C(O)=C(O3)C=3C=C(O)C(O)=CC=3)=O)=C(O)C=2)O1 IVTMALDHFAHOGL-UHFFFAOYSA-N 0.000 claims 1
- 235000001785 ferulic acid Nutrition 0.000 claims 1
- 229940114124 ferulic acid Drugs 0.000 claims 1
- KSEBMYQBYZTDHS-UHFFFAOYSA-N ferulic acid Natural products COC1=CC(C=CC(O)=O)=CC=C1O KSEBMYQBYZTDHS-UHFFFAOYSA-N 0.000 claims 1
- 238000001914 filtration Methods 0.000 claims 1
- 229930182470 glycoside Natural products 0.000 claims 1
- 229940029575 guanosine Drugs 0.000 claims 1
- RQFCJASXJCIDSX-UUOKFMHZSA-N guanosine 5'-monophosphate Chemical compound C1=2NC(N)=NC(=O)C=2N=CN1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O RQFCJASXJCIDSX-UUOKFMHZSA-N 0.000 claims 1
- 230000036541 health Effects 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 201000004332 intermediate coronary syndrome Diseases 0.000 claims 1
- GXMWXESSGGEWEM-UHFFFAOYSA-N isoquercitrin Natural products OCC(O)C1OC(OC2C(Oc3cc(O)cc(O)c3C2=O)c4ccc(O)c(O)c4)C(O)C1O GXMWXESSGGEWEM-UHFFFAOYSA-N 0.000 claims 1
- 239000007937 lozenge Substances 0.000 claims 1
- OAIJSZIZWZSQBC-GYZMGTAESA-N lycopene Chemical compound CC(C)=CCC\C(C)=C\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C=C(/C)CCC=C(C)C OAIJSZIZWZSQBC-GYZMGTAESA-N 0.000 claims 1
- 229960004999 lycopene Drugs 0.000 claims 1
- 235000012661 lycopene Nutrition 0.000 claims 1
- 239000001751 lycopene Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000012466 permeate Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 230000003331 prothrombotic effect Effects 0.000 claims 1
- OVSQVDMCBVZWGM-QSOFNFLRSA-N quercetin 3-O-beta-D-glucopyranoside Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C(C=2C=C(O)C(O)=CC=2)OC2=CC(O)=CC(O)=C2C1=O OVSQVDMCBVZWGM-QSOFNFLRSA-N 0.000 claims 1
- FDRQPMVGJOQVTL-UHFFFAOYSA-N quercetin rutinoside Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 FDRQPMVGJOQVTL-UHFFFAOYSA-N 0.000 claims 1
- SZDMSNWMQAMVTJ-UHFFFAOYSA-N quercetin-3-O-glucoside Natural products OC1OC(COC2=C(C(=O)c3cc(O)cc(O)c3O2)c4ccc(O)c(O)c4)C(O)C(O)C1O SZDMSNWMQAMVTJ-UHFFFAOYSA-N 0.000 claims 1
- FZKBNCDAGYDHTP-UHFFFAOYSA-N quercetin-3-O-glycoside Natural products OC1C(O)C(O)C(O)OC1COC1=C(C=2C=C(O)C(O)=CC=2)OC2=CC(O)=CC(O)=C2C1=O FZKBNCDAGYDHTP-UHFFFAOYSA-N 0.000 claims 1
- 208000037803 restenosis Diseases 0.000 claims 1
- IKGXIBQEEMLURG-BKUODXTLSA-N rutin Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@@H]1OC[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 IKGXIBQEEMLURG-BKUODXTLSA-N 0.000 claims 1
- ALABRVAAKCSLSC-UHFFFAOYSA-N rutin Natural products CC1OC(OCC2OC(O)C(O)C(O)C2O)C(O)C(O)C1OC3=C(Oc4cc(O)cc(O)c4C3=O)c5ccc(O)c(O)c5 ALABRVAAKCSLSC-UHFFFAOYSA-N 0.000 claims 1
- 235000005493 rutin Nutrition 0.000 claims 1
- 229960004555 rutoside Drugs 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- 238000001356 surgical procedure Methods 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
- 239000006188 syrup Substances 0.000 claims 1
- 235000020357 syrup Nutrition 0.000 claims 1
- 239000003826 tablet Substances 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
- 230000002537 thrombolytic effect Effects 0.000 claims 1
- 201000005665 thrombophilia Diseases 0.000 claims 1
- NGSWKAQJJWESNS-ZZXKWVIFSA-N trans-4-coumaric acid Chemical class OC(=O)\C=C\C1=CC=C(O)C=C1 NGSWKAQJJWESNS-ZZXKWVIFSA-N 0.000 claims 1
- QURCVMIEKCOAJU-UHFFFAOYSA-N trans-isoferulic acid Natural products COC1=CC=C(C=CC(O)=O)C=C1O QURCVMIEKCOAJU-UHFFFAOYSA-N 0.000 claims 1
- ZCIHMQAPACOQHT-ZGMPDRQDSA-N trans-isorenieratene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/c1c(C)ccc(C)c1C)C=CC=C(/C)C=Cc2c(C)ccc(C)c2C ZCIHMQAPACOQHT-ZGMPDRQDSA-N 0.000 claims 1
- DRTQHJPVMGBUCF-UHFFFAOYSA-N uracil arabinoside Natural products OC1C(O)C(CO)OC1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-UHFFFAOYSA-N 0.000 claims 1
- 229940045145 uridine Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0819959.8A GB0819959D0 (en) | 2008-10-31 | 2008-10-31 | Fruit extracts |
| GB0819959.8 | 2008-10-31 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017230562A Division JP6545237B2 (ja) | 2008-10-31 | 2017-11-30 | 果実エキス |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019172692A JP2019172692A (ja) | 2019-10-10 |
| JP2019172692A5 true JP2019172692A5 (enExample) | 2020-02-06 |
| JP7049291B2 JP7049291B2 (ja) | 2022-04-06 |
Family
ID=40138109
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011533821A Pending JP2012506901A (ja) | 2008-10-31 | 2009-11-02 | 果実エキス |
| JP2014257917A Pending JP2015057440A (ja) | 2008-10-31 | 2014-12-19 | 果実エキス |
| JP2017230562A Active JP6545237B2 (ja) | 2008-10-31 | 2017-11-30 | 果実エキス |
| JP2019112474A Active JP7049291B2 (ja) | 2008-10-31 | 2019-06-18 | 果実エキス |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011533821A Pending JP2012506901A (ja) | 2008-10-31 | 2009-11-02 | 果実エキス |
| JP2014257917A Pending JP2015057440A (ja) | 2008-10-31 | 2014-12-19 | 果実エキス |
| JP2017230562A Active JP6545237B2 (ja) | 2008-10-31 | 2017-11-30 | 果実エキス |
Country Status (19)
| Country | Link |
|---|---|
| US (4) | US20110206794A1 (enExample) |
| EP (4) | EP4218783B1 (enExample) |
| JP (4) | JP2012506901A (enExample) |
| KR (5) | KR20110093992A (enExample) |
| CN (1) | CN102271697B (enExample) |
| AU (2) | AU2009309496B2 (enExample) |
| BR (1) | BRPI0920446B1 (enExample) |
| CA (1) | CA2742213A1 (enExample) |
| DK (1) | DK2349303T3 (enExample) |
| ES (2) | ES2829974T3 (enExample) |
| GB (1) | GB0819959D0 (enExample) |
| HU (1) | HUE033986T2 (enExample) |
| IL (1) | IL212579B (enExample) |
| MX (1) | MX2011004531A (enExample) |
| NZ (1) | NZ592227A (enExample) |
| PH (2) | PH12015500810B1 (enExample) |
| PL (3) | PL3607960T3 (enExample) |
| PT (1) | PT2349303T (enExample) |
| WO (1) | WO2010049707A2 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0819958D0 (en) * | 2008-10-31 | 2008-12-10 | Provexis Natural Products Ltd | Therapeutic compositions |
| GB0819959D0 (en) | 2008-10-31 | 2008-12-10 | Provexis Natural Products Ltd | Fruit extracts |
| US9969707B2 (en) * | 2011-12-16 | 2018-05-15 | CENTRE DE RECHERCHE INDUSTRIELLE DU QUéBEC | Method for extracting anthocyanin derivatives from a plant source |
| PL2844083T3 (pl) * | 2012-04-23 | 2018-12-31 | University Of Oslo | Zastosowanie ekstraktu pomidorowego jako środka przeciwdziałającego nadciśnieniu i proces do sporządzania rozpuszczalnego w wodzie ekstraktu pomidorowego bez cukru |
| CN102796746B (zh) * | 2012-08-07 | 2014-02-19 | 山东农业大学 | 一种调节茄科类黄酮和咖啡酰奎尼酸合成的基因片段及其应用 |
| GB201223365D0 (en) | 2012-12-24 | 2013-02-06 | Provexis Natural Products Ltd | Compositions |
| EP2948005B1 (en) * | 2013-01-22 | 2020-07-15 | Lycored Ltd. | Compositions comprising heat-treated clear tomato concentrate |
| CN103293252B (zh) * | 2013-05-09 | 2015-02-04 | 杭州师范大学 | 一种中药的膜富集方法 |
| US9241677B2 (en) | 2013-07-02 | 2016-01-26 | MobHealth Corporation | Device and methods for assessing, diagnosing, and/or monitoring heart health |
| EP3050893B1 (en) | 2013-09-24 | 2020-02-26 | Ajinomoto Co., Inc. | Glycoamino acid and use thereof |
| JP6392043B2 (ja) * | 2014-09-11 | 2018-09-19 | キッコーマン株式会社 | トマト含有飲食品の呈味改善方法 |
| EP4445750A3 (en) | 2016-11-02 | 2024-12-25 | Provexis Natural Products Limited | Water soluble tomato extract protects against adverse effects of air pollution |
| CN107843665A (zh) * | 2017-11-01 | 2018-03-27 | 汤臣倍健股份有限公司 | 一种腺苷含量的测定方法及其应用 |
| CN111529711A (zh) * | 2020-05-06 | 2020-08-14 | 湖南科诺康美生命科技有限公司 | 一种抗血小板聚集的芦荟提取物及其在prp制备中的应用 |
| GB202208323D0 (en) | 2022-06-07 | 2022-07-20 | Provexis Natural Products Ltd | Compostions |
| CN115645337B (zh) * | 2022-12-23 | 2023-06-02 | 汤臣倍健股份有限公司 | 植物提取物组合物及其应用 |
| CN116803404B (zh) * | 2023-08-24 | 2023-12-15 | 汤臣倍健股份有限公司 | 水溶性番茄浓缩物在制备减少脱发、育发的产品中的应用 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6467173A (en) * | 1987-09-04 | 1989-03-13 | Sanei Kagaku Kogyo Kk | Preparation of vegetable or fruit juices |
| JP2722670B2 (ja) | 1989-05-30 | 1998-03-04 | ライオン株式会社 | 高血圧症予防用飲食品及びその製造方法 |
| US5502038A (en) * | 1993-06-21 | 1996-03-26 | Medical Research Foundation Of Oregon | Cholesterol sequestrant glycosides that inhibit intestinal cholesterol absorption |
| DE19720767A1 (de) | 1997-05-07 | 1998-11-12 | Protekum Umweltinstitut Gmbh O | Pharmazeutisches Produkt, insbesondere zur Therapie und Prophylaxe von Herz-Kreislauf-Erkrankungen |
| GB9808796D0 (en) * | 1998-04-24 | 1998-06-24 | Rowett Research Services Limit | Antithrombotic agents |
| ES2197573T3 (es) * | 1998-09-02 | 2004-01-01 | Unilever N.V. | Productos de tomate enriquecidos en beta-ciclocitral. |
| AU5965399A (en) | 1998-10-12 | 2000-05-01 | Andreas Bockelmann | Pharmaceutically active composition |
| CN1352941A (zh) | 2000-11-11 | 2002-06-12 | 吉建军 | 亚油酸胶囊 |
| CA2446274A1 (en) * | 2001-05-04 | 2002-11-14 | Ato B.V. | Novel regulatory protein |
| DE10300049A1 (de) | 2003-01-03 | 2004-07-15 | Morphochem AG Aktiengesellschaft für kombinatorische Chemie | Neue Verbindungen, die Faktor VIIa inhibieren |
| ITMI20020632A1 (it) * | 2002-03-27 | 2003-09-29 | Indena Spa | Processo per la preparazione di estratti di pomodoro ad elevato contenuto di licopene |
| AU2003261903A1 (en) | 2002-11-06 | 2004-06-07 | Kao Corporation | Blood fluidity improving agent |
| EP1633379A4 (en) * | 2003-03-27 | 2009-09-02 | Unigen Inc | COMPOSITION OF BAMBOO EXTRACT AND CORROSIVE COMPOUNDS WITH TREATMENT AND PREVENTIVE EFFECT FOR INFLAMMATORY DISEASES AND BLEACHING DISEASES |
| JP4571783B2 (ja) | 2003-04-14 | 2010-10-27 | 林原 健 | 抗微生物剤 |
| US20040223962A1 (en) * | 2003-05-07 | 2004-11-11 | Riordan Neil H. | Method and composition for preventing or reducing edema, deep vein thrombosis and/or pulmonary embolism |
| EP1481669A1 (en) | 2003-05-30 | 2004-12-01 | Yamanouchi Pharmaceutical Co. Ltd. | Use of polyhydroxy phenols and polyphenols for modulating p-selectin activity |
| EP1508325B1 (fr) * | 2003-08-21 | 2009-03-11 | Nestec S.A. | Concentré naturel de Lycopène et procédé d'obtention |
| CN1234387C (zh) * | 2004-01-12 | 2006-01-04 | 李迺灿 | 一种具有清肺功能的组合物及其制备方法 |
| FR2871378B1 (fr) | 2004-06-15 | 2007-03-30 | Seppic Sa | Nouveau medicament a base de flavanois et de leurs derives et son utilisation pour obtenir un medicament destine a la prevention de la restenose et de la maladie atheromateuse chez les patients coronariens |
| EP1640001A1 (en) | 2004-09-24 | 2006-03-29 | New Pharma Investments Holding | Composition against cardiovascular diseases |
| CN100488535C (zh) | 2004-12-09 | 2009-05-20 | 郭富凤 | 一种番茄红素混合物 |
| US7419960B2 (en) * | 2005-01-07 | 2008-09-02 | Hong Kong Baptist University | Hemiterpene glycosides with anti-platelet aggregation activities from Ilex pubescens |
| GB0502985D0 (en) * | 2005-02-14 | 2005-03-16 | Provexis Ltd | Therapeutic uses of tomato extracts |
| WO2006094120A2 (en) | 2005-03-02 | 2006-09-08 | The Regents Of The University Of California | Treatment for embolic stroke |
| JP4260158B2 (ja) * | 2005-07-07 | 2009-04-30 | 長谷川香料株式会社 | トマトジュース濃縮物の製造方法およびトマト風味組成物 |
| AT503521A1 (de) | 2006-05-05 | 2007-11-15 | Omnica Gmbh | Verwendung eines extraktes von kiwi-frucht |
| GB0610790D0 (en) * | 2006-06-02 | 2006-07-12 | Provexis Natural Products Ltd | Therapeutic uses of tomato extracts |
| US20080009449A1 (en) * | 2006-07-07 | 2008-01-10 | Kailash Prasad | Lignan complex derived from flax seed used for treatment of hypercholesterolemic atherosclerosis |
| SG191445A1 (en) | 2006-12-22 | 2013-07-31 | Univ Johns Hopkins | Anti-cholesterolemic compounds and methods of use |
| US8759327B2 (en) | 2007-04-16 | 2014-06-24 | The Regents Of The University Of Michigan | Plasminogen activator inhibitor-1 inhibitors and methods of use thereof to modulate lipid metabolism |
| GB0819959D0 (en) | 2008-10-31 | 2008-12-10 | Provexis Natural Products Ltd | Fruit extracts |
| GB0819958D0 (en) | 2008-10-31 | 2008-12-10 | Provexis Natural Products Ltd | Therapeutic compositions |
| PL2844083T3 (pl) * | 2012-04-23 | 2018-12-31 | University Of Oslo | Zastosowanie ekstraktu pomidorowego jako środka przeciwdziałającego nadciśnieniu i proces do sporządzania rozpuszczalnego w wodzie ekstraktu pomidorowego bez cukru |
| GB201223365D0 (en) * | 2012-12-24 | 2013-02-06 | Provexis Natural Products Ltd | Compositions |
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