JP2019089848A5 - - Google Patents

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Publication number
JP2019089848A5
JP2019089848A5 JP2019041615A JP2019041615A JP2019089848A5 JP 2019089848 A5 JP2019089848 A5 JP 2019089848A5 JP 2019041615 A JP2019041615 A JP 2019041615A JP 2019041615 A JP2019041615 A JP 2019041615A JP 2019089848 A5 JP2019089848 A5 JP 2019089848A5
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JP
Japan
Prior art keywords
compound
alkyl
medical device
group
crystalline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2019041615A
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English (en)
Japanese (ja)
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JP2019089848A (ja
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Publication date
Application filed filed Critical
Publication of JP2019089848A publication Critical patent/JP2019089848A/ja
Publication of JP2019089848A5 publication Critical patent/JP2019089848A5/ja
Priority to JP2021078418A priority Critical patent/JP2021121601A/ja
Priority to JP2023136964A priority patent/JP2023164476A/ja
Pending legal-status Critical Current

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JP2019041615A 2013-03-15 2019-03-07 ラパマイシン誘導体の精製 Pending JP2019089848A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2021078418A JP2021121601A (ja) 2013-03-15 2021-05-06 ラパマイシン誘導体の精製
JP2023136964A JP2023164476A (ja) 2013-03-15 2023-08-25 ラパマイシン誘導体の精製

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361799857P 2013-03-15 2013-03-15
US61/799,857 2013-03-15

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2016503426A Division JP2016519086A (ja) 2013-03-15 2014-03-17 ラパマイシン誘導体の精製

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021078418A Division JP2021121601A (ja) 2013-03-15 2021-05-06 ラパマイシン誘導体の精製

Publications (2)

Publication Number Publication Date
JP2019089848A JP2019089848A (ja) 2019-06-13
JP2019089848A5 true JP2019089848A5 (enExample) 2019-08-29

Family

ID=51538094

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2016503426A Withdrawn JP2016519086A (ja) 2013-03-15 2014-03-17 ラパマイシン誘導体の精製
JP2019041615A Pending JP2019089848A (ja) 2013-03-15 2019-03-07 ラパマイシン誘導体の精製
JP2021078418A Pending JP2021121601A (ja) 2013-03-15 2021-05-06 ラパマイシン誘導体の精製
JP2023136964A Pending JP2023164476A (ja) 2013-03-15 2023-08-25 ラパマイシン誘導体の精製

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2016503426A Withdrawn JP2016519086A (ja) 2013-03-15 2014-03-17 ラパマイシン誘導体の精製

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2021078418A Pending JP2021121601A (ja) 2013-03-15 2021-05-06 ラパマイシン誘導体の精製
JP2023136964A Pending JP2023164476A (ja) 2013-03-15 2023-08-25 ラパマイシン誘導体の精製

Country Status (8)

Country Link
US (5) US9598439B2 (enExample)
EP (1) EP2972258B1 (enExample)
JP (4) JP2016519086A (enExample)
CN (2) CN108864149B (enExample)
CA (1) CA2901162C (enExample)
ES (1) ES2897473T3 (enExample)
SG (3) SG11201507406YA (enExample)
WO (1) WO2014145780A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2934401C (en) 2009-11-02 2017-01-10 Pulse Therapeutics, Inc. Magnetomotive stator system and methods for wireless control of magnetic rotors
CN108864149B (zh) 2013-03-15 2022-04-05 生物传感器国际集团有限公司 雷帕霉素衍生物的纯化
CN109851626B (zh) * 2019-01-08 2021-11-02 扬子江药业集团四川海蓉药业有限公司 一种替西罗莫司的分离纯化方法
CN116102576B (zh) * 2021-11-09 2025-08-29 上海博畅医疗科技有限公司 一种优美莫司晶体的制造方法及其应用

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US7452692B2 (en) 2002-02-13 2008-11-18 Teva Gyógyszergyár Zártkörüen Müködö Részvénytársaság Method for extracting a macrolide from biomatter
KR20050114262A (ko) * 2003-03-31 2005-12-05 테바 기오기스제르갸르 레스즈베니타르사사그 마크로라이드의 결정화 및 정제
US7220755B2 (en) * 2003-11-12 2007-05-22 Biosensors International Group, Ltd. 42-O-alkoxyalkyl rapamycin derivatives and compositions comprising same
CA2548297C (en) * 2003-12-05 2011-06-14 Biocon Limited Process for the purification of macrolides
JP4716280B2 (ja) * 2004-03-01 2011-07-06 テルモ株式会社 Ｏ−アルキル化ラパマイシン誘導体の製造法
KR20070015544A (ko) * 2004-04-14 2007-02-05 와이어쓰 라파마이신 42-에스테르 유도체의 위치특이성 합성
WO2006060615A1 (en) 2004-12-01 2006-06-08 Teva Gyógyszergyár Zàrtköruen Muködo Rèszvènytàrsasàg Non-hygroscopic and powdery amorphous pimecrolimus
AU2006218918A1 (en) * 2005-03-02 2006-09-08 Wyeth Purification of rapamycin
US20060222627A1 (en) * 2005-03-30 2006-10-05 Andrew Carter Optimizing pharmacodynamics of therapeutic agents for treating vascular tissue
JP2009518648A (ja) * 2005-12-07 2009-05-07 ワイス 結晶性ラパマイシンを調製するための方法およびを示差走査熱量測定使用してラパマイシン化合物の結晶化度を測定するための方法
US7700614B2 (en) * 2005-12-14 2010-04-20 Abbott Laboratories One pot synthesis of tetrazole derivatives of rapamycin
GB0601406D0 (en) * 2006-01-24 2006-03-08 Novartis Ag Organic Compounds
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US7820812B2 (en) * 2006-07-25 2010-10-26 Abbott Laboratories Methods of manufacturing crystalline forms of rapamycin analogs
US7812032B2 (en) * 2006-07-25 2010-10-12 Abbott Laboratories Crystalline forms of rapamycin analogs
BRPI0621967A2 (pt) * 2006-11-10 2011-12-27 Biocon Ltd forma pura de rapamicina e um processo para recuperaÇço e purificaÇço da mesma
WO2008065887A1 (en) * 2006-11-27 2008-06-05 Terumo Kabushiki Kaisha Process for producing o-alkylated rapamycin derivative, and o-alkylated rapamycin derivative
US20080287675A1 (en) * 2007-05-18 2008-11-20 Abbott Laboratories Cascade system
CN101077334A (zh) * 2007-06-29 2007-11-28 济南康泉医药科技有限公司 含酪氨酸激酶抑制剂的抗癌组合物
TW200948361A (en) 2008-05-26 2009-12-01 Chunghwa Chemical Synthesis & Biotech Co Ltd Method for synthesizing Biolimus A9 and the like and method for improving stability of the same
US20100055145A1 (en) * 2008-08-29 2010-03-04 Biosensors International Group Stent coatings for reducing late stent thrombosis
EP2421571A2 (en) 2009-04-24 2012-02-29 Boston Scientific Scimed, Inc. Use of drug polymorphs to achieve controlled drug delivery from a coated medical device
CN102464669B (zh) * 2010-11-17 2014-04-16 浙江海正药业股份有限公司 无定形依维莫司及其制备方法
US8669360B2 (en) * 2011-08-05 2014-03-11 Boston Scientific Scimed, Inc. Methods of converting amorphous drug substance into crystalline form
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CN102786534A (zh) * 2012-05-25 2012-11-21 上海现代制药股份有限公司 一种依维莫司的制备方法
CN108864149B (zh) 2013-03-15 2022-04-05 生物传感器国际集团有限公司 雷帕霉素衍生物的纯化

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