JP2019088334A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2019088334A5 JP2019088334A5 JP2019052699A JP2019052699A JP2019088334A5 JP 2019088334 A5 JP2019088334 A5 JP 2019088334A5 JP 2019052699 A JP2019052699 A JP 2019052699A JP 2019052699 A JP2019052699 A JP 2019052699A JP 2019088334 A5 JP2019088334 A5 JP 2019088334A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- hla
- genetically modified
- nucleic acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021068195A JP7379410B2 (ja) | 2012-07-31 | 2021-04-14 | Ｈｌａ ｇ改変された細胞および方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261677739P | 2012-07-31 | 2012-07-31 | |
| US61/677,739 | 2012-07-31 | ||
| JP2018028816A JP6502544B2 (ja) | 2012-07-31 | 2018-02-21 | Ｈｌａ ｇ改変された細胞および方法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018028816A Division JP6502544B2 (ja) | 2012-07-31 | 2018-02-21 | Ｈｌａ ｇ改変された細胞および方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021068195A Division JP7379410B2 (ja) | 2012-07-31 | 2021-04-14 | Ｈｌａ ｇ改変された細胞および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019088334A JP2019088334A (ja) | 2019-06-13 |
| JP2019088334A5 true JP2019088334A5 (https=) | 2019-09-26 |
| JP7294838B2 JP7294838B2 (ja) | 2023-06-20 |
Family
ID=50028654
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015525519A Active JP6297559B2 (ja) | 2012-07-31 | 2013-07-30 | Ｈｌａｇ改変された細胞および方法 |
| JP2018028816A Active JP6502544B2 (ja) | 2012-07-31 | 2018-02-21 | Ｈｌａ ｇ改変された細胞および方法 |
| JP2019052699A Active JP7294838B2 (ja) | 2012-07-31 | 2019-03-20 | Ｈｌａ ｇ改変された細胞および方法 |
| JP2021068195A Active JP7379410B2 (ja) | 2012-07-31 | 2021-04-14 | Ｈｌａ ｇ改変された細胞および方法 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015525519A Active JP6297559B2 (ja) | 2012-07-31 | 2013-07-30 | Ｈｌａｇ改変された細胞および方法 |
| JP2018028816A Active JP6502544B2 (ja) | 2012-07-31 | 2018-02-21 | Ｈｌａ ｇ改変された細胞および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021068195A Active JP7379410B2 (ja) | 2012-07-31 | 2021-04-14 | Ｈｌａ ｇ改変された細胞および方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US9714280B2 (https=) |
| EP (4) | EP2880054B1 (https=) |
| JP (4) | JP6297559B2 (https=) |
| KR (4) | KR101923632B1 (https=) |
| CN (2) | CN113151179A (https=) |
| AU (2) | AU2013296564C1 (https=) |
| CA (1) | CA2882028C (https=) |
| ES (2) | ES2837487T3 (https=) |
| SG (1) | SG11201500799YA (https=) |
| WO (1) | WO2014022423A2 (https=) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3205636A1 (en) | 2011-04-20 | 2012-10-26 | University Of Washington Through Its Center For Commercialization | Beta-2 microglobulin-deficient cells |
| SG11201500799YA (en) | 2012-07-31 | 2015-03-30 | Basil M Hantash | Hla g-modified cells and methods |
| DK3129487T3 (da) | 2014-04-09 | 2020-11-30 | Dna Twopointo Inc | Forbedrede nukleinsyrekonstruktioner til eukaryot genekspression |
| US10344285B2 (en) | 2014-04-09 | 2019-07-09 | Dna2.0, Inc. | DNA vectors, transposons and transposases for eukaryotic genome modification |
| US9808490B2 (en) * | 2014-11-26 | 2017-11-07 | Accelerated Biosciences Corp. | Induced hepatocytes and uses thereof |
| CN116059378A (zh) | 2014-12-10 | 2023-05-05 | 明尼苏达大学董事会 | 用于治疗疾病的遗传修饰的细胞、组织和器官 |
| US20220241345A1 (en) * | 2015-10-02 | 2022-08-04 | The Regents Of The University Of California | Induced pluripotent stem cell derived glial enriched progenitor cells for the treatment of white matter stroke |
| US12544406B2 (en) | 2015-10-02 | 2026-02-10 | The Regents Of The University Of California | Induced pluripotent stem cell derived glial enriched progenitor cells for the treatment of white matter stroke |
| CA3001312A1 (en) | 2015-10-08 | 2017-04-13 | Dna2.0, Inc. | Dna vectors, transposons and transposases for eukaryotic genome modification |
| KR20230110373A (ko) * | 2016-06-14 | 2023-07-21 | 리전츠 오브 더 유니버스티 오브 미네소타 | 질환을 치료하기 위한 유전적으로 변형된 세포, 조직,및 장기 |
| BR112019001344A2 (pt) | 2016-07-26 | 2019-04-30 | The University Of North Carolina At Chapel Hill | tolerância imunológica mediada por vetor no olho |
| WO2018132479A1 (en) * | 2017-01-10 | 2018-07-19 | The General Hospital Corporation | Modified t cells and methods of their use |
| IL270835B2 (en) * | 2017-06-12 | 2025-01-01 | Sinai Health Sys | Allograft tolerance without the need for systemic immunosuppression |
| EP3731876A4 (en) * | 2017-12-28 | 2022-04-06 | Gritstone bio, Inc. | ANTIGEN-BINDING PROTEINS TARGETING SHARED ANTIGENS |
| JP7241161B2 (ja) | 2018-08-01 | 2023-03-16 | イミュニティーバイオ、インコーポレイテッド | 細胞免疫療法の安定した遺伝子改変のための、ホーミング受容体又はサイトカインとキメラ抗原受容体とを含むクアドリシストロニックシステム |
| US10883084B2 (en) | 2018-10-05 | 2021-01-05 | Xenotherapeutics, Inc. | Personalized cells, tissues, and organs for transplantation from a humanized, bespoke, designated-pathogen free, (non-human) donor and methods and products relating to same |
| TW202043463A (zh) * | 2018-12-14 | 2020-12-01 | 比利時商普羅米修亞生物科技股份有限公司 | 包含表現hla-e之肝先驅細胞之細胞組成物 |
| TW202035682A (zh) | 2018-12-14 | 2020-10-01 | 比利時商普羅米修亞生物科技股份有限公司 | 表現hla-g之肝先驅細胞及取得包含該等細胞之此等細胞組成物之方法與其用途 |
| US11230699B2 (en) | 2020-01-28 | 2022-01-25 | Immunitybio, Inc. | Chimeric antigen receptor-modified NK-92 cells targeting EGFR super-family receptors |
| JP2023513263A (ja) * | 2020-02-10 | 2023-03-30 | ルビウス セラピューティクス， インコーポレイテッド | Ｈｌａ－ｇポリペプチドを含む操作された赤血球系細胞およびその使用方法 |
| WO2021241658A1 (ja) * | 2020-05-26 | 2021-12-02 | 株式会社ヘリオス | 低免疫原性細胞 |
| EP4200023A4 (en) * | 2020-08-23 | 2024-10-30 | Applied StemCell, Inc. | Hla-f-modified cells and methods |
| US11459372B2 (en) | 2020-11-30 | 2022-10-04 | Crispr Therapeutics Ag | Gene-edited natural killer cells |
| WO2022144632A1 (en) | 2020-12-30 | 2022-07-07 | Crispr Therapeutics Ag | Compositions and methods for differentiating stem cells into nk cells |
| CN113234664B (zh) * | 2021-05-11 | 2024-05-10 | 澳门大学 | 一种胰腺祖细胞的制备方法及其应用 |
| JP2024540987A (ja) * | 2021-10-21 | 2024-11-06 | バーテックス ファーマシューティカルズ インコーポレイテッド | 低免疫細胞 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1990002806A1 (en) | 1988-09-01 | 1990-03-22 | Whitehead Institute For Biomedical Research | Recombinant retroviruses with amphotropic and ecotropic host ranges |
| US5464764A (en) | 1989-08-22 | 1995-11-07 | University Of Utah Research Foundation | Positive-negative selection methods and vectors |
| US5534423A (en) | 1993-10-08 | 1996-07-09 | Regents Of The University Of Michigan | Methods of increasing rates of infection by directing motion of vectors |
| US6686198B1 (en) | 1993-10-14 | 2004-02-03 | President And Fellows Of Harvard College | Method of inducing and maintaining neuronal cells |
| US6013517A (en) | 1994-05-09 | 2000-01-11 | Chiron Corporation | Crossless retroviral vectors |
| US5650135A (en) | 1994-07-01 | 1997-07-22 | The Board Of Trustees Of The Leland Stanford Junior University | Non-invasive localization of a light-emitting conjugate in a mammal |
| US5843780A (en) | 1995-01-20 | 1998-12-01 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells |
| US5741657A (en) | 1995-03-20 | 1998-04-21 | The Regents Of The University Of California | Fluorogenic substrates for β-lactamase and methods of use |
| US5744320A (en) | 1995-06-07 | 1998-04-28 | Promega Corporation | Quenching reagents and assays for enzyme-mediated luminescence |
| US6982431B2 (en) | 1998-08-31 | 2006-01-03 | Molecular Devices Corporation | Sample analysis systems |
| US6031094A (en) | 1998-07-23 | 2000-02-29 | The Regents Of The University Of California | Beta-lactam substrates and uses thereof |
| US7005252B1 (en) | 2000-03-09 | 2006-02-28 | Wisconsin Alumni Research Foundation | Serum free cultivation of primate embryonic stem cells |
| CN1302115C (zh) | 2001-04-23 | 2007-02-28 | 埃麦克萨有限公司 | 电穿孔用缓冲溶液及上述溶液的使用方法 |
| EP1543110A4 (en) | 2002-05-17 | 2006-09-06 | Sinai School Medicine | POPULATION OF DEFINITIVE ENDODERMIC CELLS AND MESODERMAL |
| EP2341134B1 (en) | 2003-01-31 | 2014-08-27 | Promega Corporation | Covalent tethering of functional groups to proteins |
| WO2005034624A2 (en) | 2003-05-21 | 2005-04-21 | The General Hospital Corporation | Microfabricated compositions and processes for engineering tissues containing multiple cell types |
| PT1675956E (pt) * | 2003-10-21 | 2010-11-04 | Merck Serono Sa | Sequência mínima de adn que actua como um isolador de cromatina e sua utilização na expressão de proteína |
| US8673634B2 (en) | 2003-11-13 | 2014-03-18 | Massachusetts Eye & Ear Infirmary | Method for the treatment of hearing loss |
| KR101271884B1 (ko) * | 2004-11-08 | 2013-06-05 | 크로마제닉스 비.브이. | 고수준으로 단백질을 발현하는 숙주세포의 선택 |
| US20070036773A1 (en) * | 2005-08-09 | 2007-02-15 | City Of Hope | Generation and application of universal T cells for B-ALL |
| CN103555655B (zh) * | 2005-10-21 | 2018-02-27 | 细胞研究私人有限公司 | 自脐带羊膜分离和培养干/祖细胞及其分化的细胞的应用 |
| US8048999B2 (en) | 2005-12-13 | 2011-11-01 | Kyoto University | Nuclear reprogramming factor |
| US8278104B2 (en) | 2005-12-13 | 2012-10-02 | Kyoto University | Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2 |
| US20090156532A1 (en) * | 2006-01-24 | 2009-06-18 | The University Of Chicago | SNP BINDING SITE FOR microRNAs IN HLA-G |
| WO2007091078A2 (en) * | 2006-02-10 | 2007-08-16 | Axordia Limited | Polypeptide conjugate comprising hla-g and uses thereof, stem cells transfected with hla-g |
| EP2087107A2 (en) | 2006-10-30 | 2009-08-12 | Promega Corporation | Mutant hydrolase proteins with enhanced kinetics and functional expression |
| US8647871B2 (en) * | 2007-03-30 | 2014-02-11 | Escape Therapeutics, Inc. | Endogenous expression of HLA-G and/or HLA-E by mesenchymal cells |
| JP2012508591A (ja) * | 2008-11-14 | 2012-04-12 | ライフ テクノロジーズ コーポレーション | 細胞を操作するための組成物および方法 |
| US8592211B2 (en) | 2009-03-20 | 2013-11-26 | The Rockefeller University | Enhanced PiggyBac transposon and methods for transposon mutagenesis |
| US8048675B1 (en) | 2010-05-12 | 2011-11-01 | Ipierian, Inc. | Integration-free human induced pluripotent stem cells from blood |
| SG11201500799YA (en) | 2012-07-31 | 2015-03-30 | Basil M Hantash | Hla g-modified cells and methods |
| CN103333861A (zh) * | 2013-06-03 | 2013-10-02 | 浙江省台州医院 | 特异性表达hla-g1抗原的细胞株k562 |
| CN111808819A (zh) * | 2020-05-26 | 2020-10-23 | 台州恩泽医疗中心(集团) | 表达hla-g3异构体标准蛋白的细胞株及其应用 |
-
2013
- 2013-07-30 SG SG11201500799YA patent/SG11201500799YA/en unknown
- 2013-07-30 ES ES18211100T patent/ES2837487T3/es active Active
- 2013-07-30 KR KR1020157005165A patent/KR101923632B1/ko active Active
- 2013-07-30 EP EP13825511.2A patent/EP2880054B1/en active Active
- 2013-07-30 KR KR1020187034048A patent/KR102055438B1/ko active Active
- 2013-07-30 CA CA2882028A patent/CA2882028C/en active Active
- 2013-07-30 ES ES13825511T patent/ES2716577T3/es active Active
- 2013-07-30 EP EP20196775.9A patent/EP3805261A1/en not_active Withdrawn
- 2013-07-30 KR KR1020207033804A patent/KR102366081B1/ko active Active
- 2013-07-30 EP EP21209423.9A patent/EP4015530A1/en active Pending
- 2013-07-30 CN CN202110063720.2A patent/CN113151179A/zh active Pending
- 2013-07-30 WO PCT/US2013/052767 patent/WO2014022423A2/en not_active Ceased
- 2013-07-30 EP EP18211100.5A patent/EP3483178B1/en active Active
- 2013-07-30 JP JP2015525519A patent/JP6297559B2/ja active Active
- 2013-07-30 KR KR1020197036122A patent/KR102184947B1/ko active Active
- 2013-07-30 AU AU2013296564A patent/AU2013296564C1/en not_active Ceased
- 2013-07-30 CN CN201380051169.3A patent/CN105612176B/zh active Active
-
2015
- 2015-01-28 US US14/608,004 patent/US9714280B2/en active Active
-
2017
- 2017-06-16 US US15/625,964 patent/US10502738B2/en active Active
-
2018
- 2018-02-21 JP JP2018028816A patent/JP6502544B2/ja active Active
- 2018-08-23 AU AU2018220087A patent/AU2018220087B2/en not_active Ceased
-
2019
- 2019-03-20 JP JP2019052699A patent/JP7294838B2/ja active Active
- 2019-10-22 US US16/659,918 patent/US11977073B2/en active Active
-
2020
- 2020-03-27 US US16/832,321 patent/US20200309776A1/en not_active Abandoned
-
2021
- 2021-04-14 JP JP2021068195A patent/JP7379410B2/ja active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2019088334A5 (https=) | ||
| JP2015529457A5 (https=) | ||
| JP6502544B2 (ja) | Ｈｌａ ｇ改変された細胞および方法 | |
| JP6970106B2 (ja) | Ｖｃｎエンハンサー組成物およびその使用方法 | |
| ES2601845T3 (es) | Aislamiento y purificación de células madre hematopoyéticas a partir de lipoaspirados post-liposucción | |
| JP2021534806A (ja) | ユニバーサルドナー細胞 | |
| JP2020509780A (ja) | 細胞並びにその使用方法及び製造方法 | |
| US9228007B1 (en) | Recombinant human progenitor cells, engineered human thymocytes, and engineered human T cells | |
| CN114026225A (zh) | 安全的免疫隐形细胞 | |
| IL293552A (en) | Modulators of the immune escape mechanism for universal cell therapy | |
| US20230235280A1 (en) | Modified stem cells and methods of use thereof | |
| JP2022551478A (ja) | 持続的トランスジーン発現を伴う細胞 | |
| JP7016556B2 (ja) | 脳由来神経栄養因子を発現する間葉系幹細胞およびその用途 | |
| Lim et al. | Microporation is a valuable transfection method for efficient gene delivery into human umbilical cord blood-derived mesenchymal stem cells | |
| CA3100262A1 (en) | Compositions and methods for haematopoietic stem cell transplantation | |
| JP2024535677A5 (https=) | ||
| CN117716026A (zh) | 具有氧化应激抗性的间充质干细胞、其制备方法及用途 | |
| WO2016112779A1 (en) | Modified cells evoking reduced immunogenic responses | |
| JP5745419B2 (ja) | 細胞、核酸構築物、前記構築物を含む細胞、及び疾患の治療において前記細胞を利用する方法 | |
| JP6691756B2 (ja) | 合成ペプチドを用いた神経幹細胞の生産方法 | |
| JP2021503008A (ja) | 造血幹細胞および前駆細胞移植療法のための組成物および方法 | |
| CN120615119A (zh) | 用于同种异体细胞疗法以覆盖全球、种族或特定疾病群体的免疫相容细胞 | |
| CN116396940A (zh) | 造血干祖细胞及其制备方法和用途 | |
| Carretero et al. | Applicability of bioengineered human skin: from preclinical skin humanized mouse models to clinical regenerative therapies | |
| CN100408677C (zh) | 一种bdnf基因修饰的间充质干细胞的构建方法 |