JP2019048895A5 - - Google Patents

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Publication number
JP2019048895A5
JP2019048895A5 JP2018246722A JP2018246722A JP2019048895A5 JP 2019048895 A5 JP2019048895 A5 JP 2019048895A5 JP 2018246722 A JP2018246722 A JP 2018246722A JP 2018246722 A JP2018246722 A JP 2018246722A JP 2019048895 A5 JP2019048895 A5 JP 2019048895A5
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JP
Japan
Prior art keywords
citrullinated
antibody
seq
amino acid
acid sequence
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JP2018246722A
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English (en)
Japanese (ja)
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JP2019048895A (ja
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JP2018246722A 2013-10-22 2018-12-28 Tlr4リガンドまたは他のバイオマーカーのレベルが上昇した患者における障害の診断および処置を行うための方法および組成物 Withdrawn JP2019048895A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361894042P 2013-10-22 2013-10-22
US61/894,042 2013-10-22

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2016525584A Division JP2016539925A (ja) 2013-10-22 2014-10-22 Tlr4リガンドまたは他のバイオマーカーのレベルが上昇した患者における障害の診断および処置を行うための方法および組成物

Related Child Applications (1)

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JP2020177986A Division JP2021006592A (ja) 2013-10-22 2020-10-23 Tlr4リガンドまたは他のバイオマーカーのレベルが上昇した患者における障害の診断および処置を行うための方法および組成物

Publications (2)

Publication Number Publication Date
JP2019048895A JP2019048895A (ja) 2019-03-28
JP2019048895A5 true JP2019048895A5 (enExample) 2019-09-12

Family

ID=51866128

Family Applications (3)

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JP2016525584A Pending JP2016539925A (ja) 2013-10-22 2014-10-22 Tlr4リガンドまたは他のバイオマーカーのレベルが上昇した患者における障害の診断および処置を行うための方法および組成物
JP2018246722A Withdrawn JP2019048895A (ja) 2013-10-22 2018-12-28 Tlr4リガンドまたは他のバイオマーカーのレベルが上昇した患者における障害の診断および処置を行うための方法および組成物
JP2020177986A Pending JP2021006592A (ja) 2013-10-22 2020-10-23 Tlr4リガンドまたは他のバイオマーカーのレベルが上昇した患者における障害の診断および処置を行うための方法および組成物

Family Applications Before (1)

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JP2016525584A Pending JP2016539925A (ja) 2013-10-22 2014-10-22 Tlr4リガンドまたは他のバイオマーカーのレベルが上昇した患者における障害の診断および処置を行うための方法および組成物

Family Applications After (1)

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JP2020177986A Pending JP2021006592A (ja) 2013-10-22 2020-10-23 Tlr4リガンドまたは他のバイオマーカーのレベルが上昇した患者における障害の診断および処置を行うための方法および組成物

Country Status (7)

Country Link
US (2) US9688769B2 (enExample)
EP (1) EP3060250A1 (enExample)
JP (3) JP2016539925A (enExample)
CN (1) CN105899231A (enExample)
AU (2) AU2014338991B2 (enExample)
CA (1) CA2928317A1 (enExample)
WO (1) WO2015059168A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE037613T2 (hu) * 2012-03-29 2018-09-28 Novimmune Sa Anti-TLR4 antitestek és azok felhasználása
EP3060250A1 (en) 2013-10-22 2016-08-31 NovImmune SA Methods and compositions for diagnosis and treatment of disorders in patients with elevated levels of tlr4 ligands and other biomarkers
WO2017021552A1 (en) * 2015-08-06 2017-02-09 Novimmune Sa Methods and compositions for identifying patient populations for diagnosis and treatment of tlr4-dependent disorders
WO2018065300A1 (en) * 2016-10-04 2018-04-12 F. Hoffmann-La Roche Ag System and method for identification of a synthetic classifier
EP3580571B1 (en) 2017-02-07 2023-06-07 Lyfstone B.V. Biomarkers for diagnosing implant related risk of implant revision due to aseptic loosening
WO2020225549A1 (en) * 2019-05-06 2020-11-12 The Francis Crick Institute Limited Method for preventing inflammation
JP7807372B2 (ja) * 2019-12-20 2026-01-27 ハドソン インスティチュート オブ メディカル リサーチ Cxcl10結合タンパク質及びその使用
WO2021212222A1 (en) * 2020-04-20 2021-10-28 Edesa Biotech Research Inc. Compositions and methods for treatment of acute respiratory distress syndrome
CN113358872B (zh) * 2021-06-03 2022-10-21 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) 用于评估肿瘤免疫治疗疗效的标志物组及系统

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
US7674884B2 (en) * 2003-12-10 2010-03-09 Novimmune S.A. Neutralizing antibodies and methods of use thereof
ATE544783T1 (de) * 2003-12-10 2012-02-15 Novimmune Sa Neutralisierende anti tlr4/md-2 antikörper und verfahren zu deren verwendung
US7312320B2 (en) 2003-12-10 2007-12-25 Novimmune Sa Neutralizing antibodies and methods of use thereof
AU2005272598B2 (en) 2004-08-12 2011-11-17 Helsinn Therapeutics (U.S.), Inc. Method of stimulating the motility of the gastrointestinal system using growth hormone secretagogues
DE602005021694D1 (de) * 2004-12-10 2010-07-15 Novimmune Sa Kombinationstherapien gegen multiple toll-like-rezeptoren und ihre verwendung
KR101379693B1 (ko) 2005-08-25 2014-04-10 크리어빌리스 쎄라퓨틱스 에스.피.에이. K-252a 및 그의 유도체의 중합체 컨쥬게이트
CN101248105B (zh) * 2005-08-25 2012-10-10 克雷毕里斯治疗股份公司 K-252a及其衍生物的聚合物缀合物
US20070148704A1 (en) 2005-10-06 2007-06-28 Ursula Klause Anti-CCPand antinuclear antibodies in diagnosis of rheumatoid arthritis
US7712333B2 (en) 2006-03-29 2010-05-11 Asahi Glass Company, Limited Method for smoothing a surface of a glass substrate for a reflective mask blank used in EUV lithography
SI2173381T1 (sl) * 2007-05-14 2014-01-31 Novimmune Sa Fc receptor-vezavni polipeptidi z modificiranimi efektorskimi funkcijami
CN101589491B (zh) 2007-07-24 2011-07-27 松下电器产业株式会社 镍氢电池用负极材料及其处理方法以及镍氢电池
WO2009138494A2 (en) 2008-05-15 2009-11-19 Ablynx N.V. Amino acid sequences directed against toll-like receptors and polypeptides comprising the same for the treatment of diseases related to toll-like receptors
US9140701B2 (en) * 2009-08-18 2015-09-22 The Board Of Trustees Of The Leland Stanford Junior University Fibrinogen immune complexes to diagnose and guide therapy in rheumatoid arthritis
AU2011325134B2 (en) 2010-11-05 2014-10-23 Novartis Ag Methods of treating rheumatoid arthritis using IL-17 antagonists
JP6289098B2 (ja) * 2011-01-10 2018-03-07 ノビミューン エスアー 抗tlr4抗体およびその使用法
US20140378531A1 (en) * 2012-02-01 2014-12-25 New York University Inhibition of pattern recognition receptors in pancreatic cancer treatment using tlr inhibitors
WO2015010791A2 (en) 2013-07-24 2015-01-29 Klareskog, Lars Novel antibodies for the diagnosis and treatment of rheumatoid arthritis
EP3060250A1 (en) 2013-10-22 2016-08-31 NovImmune SA Methods and compositions for diagnosis and treatment of disorders in patients with elevated levels of tlr4 ligands and other biomarkers

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