HK1219512A1 - 用於診斷和治療炎性腸病的方法 - Google Patents

用於診斷和治療炎性腸病的方法

Info

Publication number
HK1219512A1
HK1219512A1 HK16107516.2A HK16107516A HK1219512A1 HK 1219512 A1 HK1219512 A1 HK 1219512A1 HK 16107516 A HK16107516 A HK 16107516A HK 1219512 A1 HK1219512 A1 HK 1219512A1
Authority
HK
Hong Kong
Prior art keywords
diagnosing
methods
inflammatory bowel
bowel disease
treating inflammatory
Prior art date
Application number
HK16107516.2A
Other languages
English (en)
Inventor
Jason A Hackney
Mary Keir
Lilyan Yi Tian Wright
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1219512A1 publication Critical patent/HK1219512A1/zh

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/06—Gastro-intestinal diseases
    • G01N2800/065—Bowel diseases, e.g. Crohn, ulcerative colitis, IBS

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK16107516.2A 2013-05-17 2016-06-28 用於診斷和治療炎性腸病的方法 HK1219512A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361824661P 2013-05-17 2013-05-17
PCT/US2014/038434 WO2014186728A2 (en) 2013-05-17 2014-05-16 Methods for diagnosing and treating inflammatory bowel disease

Publications (1)

Publication Number Publication Date
HK1219512A1 true HK1219512A1 (zh) 2017-04-07

Family

ID=51899021

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16107516.2A HK1219512A1 (zh) 2013-05-17 2016-06-28 用於診斷和治療炎性腸病的方法

Country Status (11)

Country Link
US (1) US20160178644A1 (zh)
EP (1) EP2997162A4 (zh)
JP (1) JP2016521540A (zh)
KR (1) KR20160005044A (zh)
CN (1) CN105209643A (zh)
BR (1) BR112015028338A2 (zh)
CA (1) CA2910199A1 (zh)
HK (1) HK1219512A1 (zh)
MX (1) MX2015015784A (zh)
RU (1) RU2015149032A (zh)
WO (1) WO2014186728A2 (zh)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2017009695A (es) 2015-01-29 2018-04-10 Univ Oxford Innovation Ltd Objetivo terapeutico y biomarcador en enfermedad inflamatoria intestinal (ibd).
GB201616557D0 (en) * 2016-09-29 2016-11-16 Secretary Of State For Health The Assay for distinguishing between sepsis and systemic inflammatory response syndrome
US11978543B2 (en) 2016-12-14 2024-05-07 Astarte Medical Partners Inc. System and methods for developing and using a microbiome-based action component
WO2018112209A1 (en) * 2016-12-14 2018-06-21 Warren Tracy System and methods for developing and using a microbiome-based action component for patient health
WO2018126009A1 (en) * 2016-12-29 2018-07-05 University Of Miami Method for modulating inflammasome activity and inflammation in the lung
US11840565B2 (en) 2016-12-29 2023-12-12 University Of Miami Methods and compositions for treating virus-associated inflammation
EP3654993A4 (en) * 2017-07-17 2021-08-25 The Broad Institute, Inc. HUMAN COLON CELL ATLAS IN GOOD HEALTH WITH HEMORRHAGIC RECTO-COLITIS
EP3655433A4 (en) * 2017-07-18 2021-05-05 Washington University METHODS AND USES OF BIOMARKERS OF INFLAMMATORY INTESTINAL DISEASE
GB201717301D0 (en) * 2017-10-20 2017-12-06 Nordic Bioscience As Type xvi collagen assay
CA3090951C (en) * 2018-02-12 2023-10-17 F.Hoffmann-La Roche Ag Method of predicting response to therapy by assessing tumor genetic heterogeneity
CA3121167A1 (en) * 2018-11-29 2020-06-04 Cedars-Sinai Medical Center Methods of stratifying and treating a sub-population of inflammatory bowel disease patients
WO2020241778A1 (ja) * 2019-05-29 2020-12-03 国立大学法人九州大学 線維化を抑制する医薬組成物
KR102577697B1 (ko) * 2019-11-13 2023-09-14 주식회사 나이벡 염증 및 상처 치료용 펩타이드
CA3180628A1 (en) * 2020-06-03 2021-12-09 Rebecca GONSKY Treatments for a sub-population of inflammatory bowel disease patients
WO2022140667A2 (en) * 2020-12-23 2022-06-30 Icahn School Of Medicine At Mount Sinai Method for treating crohn's disease
JPWO2023286694A1 (zh) 2021-07-13 2023-01-19

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1667669A2 (en) * 2003-05-30 2006-06-14 Molecular Staging, Inc. Inflammatory bowel diseases
US20100093552A1 (en) * 2008-10-09 2010-04-15 Asit Panja Use and identification of biomarkers for gastrointestinal diseases
NZ619527A (en) * 2009-04-14 2015-06-26 Nestec Sa Inflammatory bowel disease prognostics
WO2011011339A1 (en) * 2009-07-20 2011-01-27 Genentech, Inc. Gene expression markers for crohn's disease
CN103154032A (zh) * 2010-08-13 2013-06-12 弗·哈夫曼-拉罗切有限公司 用于疾病治疗的针对IL-1β和IL-18的抗体

Also Published As

Publication number Publication date
EP2997162A2 (en) 2016-03-23
US20160178644A1 (en) 2016-06-23
EP2997162A4 (en) 2017-02-01
CN105209643A (zh) 2015-12-30
CA2910199A1 (en) 2014-11-20
MX2015015784A (es) 2016-03-11
BR112015028338A2 (pt) 2017-07-25
RU2015149032A (ru) 2017-06-22
JP2016521540A (ja) 2016-07-25
KR20160005044A (ko) 2016-01-13
WO2014186728A2 (en) 2014-11-20
WO2014186728A3 (en) 2015-01-22

Similar Documents

Publication Publication Date Title
HK1219512A1 (zh) 用於診斷和治療炎性腸病的方法
IL269529A (en) Methods for diagnosing and treating inflammatory bowel disease
IL276516A (en) Methods for diagnosing and treating inflammatory bowel disease
EP2971127A4 (en) DIAGNOSTIC AND TREATMENT METHODS FOR INFLAMMATORY INTESTINAL DISEASE
ZA201504861B (en) Apparatus for improved disease detection
PL3046470T3 (pl) Diagnozowanie i leczenie zaburzeń ruchu
HK1221393A1 (zh) 不用結腸切除術治療炎性腸病的方法和組合物
HK1215373A1 (zh) 用於治療代謝疾病的方法和裝置
HK1221898A1 (zh) 腸易激綜合徵和炎性腸病的診斷和治療
IL245602A0 (en) Compositions and methods for evaluating intestinal function
ZA201408059B (en) Compositions and methods for the treatment of inflammatory bowel disease
EP3024482A4 (en) Methods for diagnosing and treating immune disease
GB201306434D0 (en) Methods and apparatus for quantifying inflammation
GB201223223D0 (en) Inflammatory bowel disease
EP3069726A4 (en) Agent and method for treating autoimmune disease
HK1218249A1 (zh) 用於治療炎症性腸道疾病的化合物和方法
GB201307256D0 (en) Diagnostic method
HK1222400A1 (zh) 抗嗜酸細胞活化趨化因數抗體在治療炎症性腸病中的應用
GB201309358D0 (en) Aiding assessment of prognosis in inflammatory disease
GB201308259D0 (en) Cancer diagnosis and monitoring
HUE036747T2 (hu) Gyulladásos bélbetegség kezelése klinoptilolittal
EP2997369A4 (en) METHOD AND COMPOSITIONS FOR DETERMINING THE REASON FOR INFLAMMATORY ENDURANCE
GB201302884D0 (en) Novel methods for diagnosis and therapy
GB201318088D0 (en) Oligonucleotide probe set and methods for the diagnosis of irritable bowel syndrome and inflammatory bowel disease
GB201308754D0 (en) Disease monitoring system and method thereof