JP2018534536A - 臨床上の用途のための、分析物の収集、抽出、濃縮、及び検出のための方法及び装置 - Google Patents

臨床上の用途のための、分析物の収集、抽出、濃縮、及び検出のための方法及び装置 Download PDF

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JP2018534536A
JP2018534536A JP2018511707A JP2018511707A JP2018534536A JP 2018534536 A JP2018534536 A JP 2018534536A JP 2018511707 A JP2018511707 A JP 2018511707A JP 2018511707 A JP2018511707 A JP 2018511707A JP 2018534536 A JP2018534536 A JP 2018534536A
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phase solution
bacteria
sample
atps
lfa
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JP2018534536A5 (enExample
Inventor
ダニエル・ティー・カメイ
イン・ト・チュウ
ベンジャミン・エム・ウ
ギャレット・エル・モスリー
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University of California
University of California Berkeley
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University of California San Diego UCSD
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56927—Chlamydia
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/4833—Physical analysis of biological material of solid biological material, e.g. tissue samples, cell cultures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/493—Physical analysis of biological material of liquid biological material urine
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346—Nanoparticles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54391—Immunochromatographic test strips based on vertical flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545—Synthetic resin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56944—Streptococcus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56961—Plant cells or fungi
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses

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  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
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  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
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  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
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  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • Ecology (AREA)
  • Optics & Photonics (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Nanotechnology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2018511707A 2015-09-04 2016-09-02 臨床上の用途のための、分析物の収集、抽出、濃縮、及び検出のための方法及び装置 Pending JP2018534536A (ja)

Priority Applications (1)

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JP2022028070A JP7399994B2 (ja) 2015-09-04 2022-02-25 臨床上の用途のための、分析物の収集、抽出、濃縮、及び検出のための方法及び装置

Applications Claiming Priority (3)

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US201562214801P 2015-09-04 2015-09-04
US62/214,801 2015-09-04
PCT/US2016/050257 WO2017041030A1 (en) 2015-09-04 2016-09-02 Methods and devices for analyte collection, extraction, concentration, and detection for clinical applications

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JP2022028070A Division JP7399994B2 (ja) 2015-09-04 2022-02-25 臨床上の用途のための、分析物の収集、抽出、濃縮、及び検出のための方法及び装置

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JP2018534536A5 JP2018534536A5 (enExample) 2019-10-10

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JP2022028070A Active JP7399994B2 (ja) 2015-09-04 2022-02-25 臨床上の用途のための、分析物の収集、抽出、濃縮、及び検出のための方法及び装置

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US (2) US11287426B2 (enExample)
EP (1) EP3345001A4 (enExample)
JP (2) JP2018534536A (enExample)
KR (1) KR102693068B1 (enExample)
CN (1) CN108139402B (enExample)
AU (1) AU2016318103B2 (enExample)
CA (1) CA3002020C (enExample)
HK (1) HK1257999A1 (enExample)
WO (1) WO2017041030A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022154826A (ja) * 2021-03-30 2022-10-13 東洋紡株式会社 ビタミンａの定量方法

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102630880B1 (ko) 2014-03-07 2024-01-29 더 리전트 오브 더 유니버시티 오브 캘리포니아 분석물 추출, 농축 및 검출을 통합하기 위한 장치
WO2017041030A1 (en) 2015-09-04 2017-03-09 The Regents Of The University Of California Methods and devices for analyte collection, extraction, concentration, and detection for clinical applications
EP4202439B1 (en) 2016-06-09 2025-02-19 The Regents of the University of California Method of purifying and amplifying a nucleic acid
US11327075B2 (en) 2016-08-22 2022-05-10 The Regents Of The University Of California Hydrogel platform for aqueous two-phase concentration of a target to enhance its detection
JP7145517B2 (ja) 2017-03-08 2022-10-03 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン 分析物の検出
US11209427B2 (en) 2017-03-27 2021-12-28 The Regents Of The University Of California Semi-quantitative lateral-flow immunoassay for the detection of CSF leaks
WO2018183454A1 (en) * 2017-03-28 2018-10-04 Chiu Yin To Method and device for accurate diagnosis of dental diseases
CN110462400B (zh) 2017-03-28 2022-06-21 相达生物科技国际有限公司 用于在液体活检中准确诊断疾病靶向生物标记的方法
EP3635400A4 (en) * 2017-05-31 2021-02-24 The Regents of The University of California SINGLE-LEVEL, ATPS-EXTENDED LFA DIAGNOSTIC DESIGN
CN119425158A (zh) 2017-06-01 2025-02-14 相达生物科技美国有限公司 用于多孔材料中双水相分离的相分离行为改性剂
US11609232B2 (en) 2017-09-01 2023-03-21 Phase Diagnostics, Inc. Method and device of using aqueous two-phase systems (ATPS) for enhancing diagnostics for sexually transmitted infections
US20200318153A1 (en) * 2017-09-01 2020-10-08 Phase Diagnostics, Inc. Method and device of using aqueous two-phase systems (ATPS) for enhancing diagnostics for dental and oral diseases
JP7323532B2 (ja) * 2017-09-18 2023-08-08 フェーズ サイエンティフィック インターナショナル リミテッド 短い核酸断片の単離、精製及び／又は濃縮のために水性二相系を使用する方法
WO2019118705A1 (en) * 2017-12-14 2019-06-20 The Regents Of The University Of Michigan Concentration of analytes
WO2019118712A1 (en) * 2017-12-14 2019-06-20 Yin To Chiu One-step isolation, concentration and/or purification of nucleic acids using atps-embedded microfluidic device
WO2019143943A2 (en) 2018-01-19 2019-07-25 Yin To Chiu Composition and method for concentration and enrichment of nucleic acids
US12043826B2 (en) 2018-01-19 2024-07-23 Phase Scientific International, Ltd. Spontaneous nucleic acid purification and concentration in a single step
US11643646B2 (en) 2018-01-19 2023-05-09 Phase Scientific International, Ltd. Method for isolating and purifying nucleic acids using a solid-liquid phase system
WO2019144016A1 (en) 2018-01-19 2019-07-25 Yin To Chiu Method of isolating exosomes using encapsulation and aqueous micellar system
AU2021239220B2 (en) 2020-03-20 2024-11-14 Phase Scientific International, Ltd. Compositions and methods for ribonucleic acid extraction
US20230201824A1 (en) * 2020-08-17 2023-06-29 University Of Washington Long-term dry storage of enzyme-based reagents in a porous matrix
CN112881700A (zh) * 2021-01-12 2021-06-01 瑞吉瑞得医药生物科技(无锡)有限公司 一种用于全血样本预处理的磷酸盐缓冲液及其使用方法
US12144493B2 (en) * 2021-03-24 2024-11-19 National Defense Medical Center Collection and test device for rapid test
CN113189347A (zh) * 2021-05-12 2021-07-30 瑞吉瑞得医药生物科技(无锡)有限公司 一种用于老年痴呆病血清中A-beta抗原检测的胶体金试纸及其使用方法
US20240255395A1 (en) * 2021-06-03 2024-08-01 Regents Of The University Of Minnesota Methods, devices and systems for separating biological analytes from samples
CN119137270A (zh) 2022-11-02 2024-12-13 相达生物科技国际有限公司 使用atps和固相介质从生物样品分离目标分析物的方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011159537A2 (en) * 2010-06-15 2011-12-22 The Regents Of The University Of California Method and device for analyte detection
US20120238008A1 (en) * 2011-03-15 2012-09-20 Colorado State University Research Foundation Rapid Detection of Pathogens Using Paper Devices

Family Cites Families (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2020029A1 (en) 1989-07-12 1991-01-13 Yatin B. Thakore Device and method for separation of plasma from blood and determination of blood analytes
US5141850A (en) 1990-02-07 1992-08-25 Hygeia Sciences, Inc. Porous strip form assay device method
US5710005A (en) 1996-10-29 1998-01-20 Biocode, Inc. Analyte detection with a gradient lateral flow device
US6979576B1 (en) 1997-07-25 2005-12-27 Shu-Ching Cheng Methods of use of one step immunochromatographic device for Streptococcus A antigen
US6194221B1 (en) 1996-11-19 2001-02-27 Wyntek Diagnostics, Inc. Hybrid one-step immunochromatographic device and method of use
US6924153B1 (en) 1997-03-06 2005-08-02 Quidel Corporation Quantitative lateral flow assays and devices
US6394952B1 (en) 1998-02-03 2002-05-28 Adeza Biomedical Corporation Point of care diagnostic systems
WO1999047930A1 (en) 1998-03-16 1999-09-23 Quidel Corporation Immunoassay device and method
US7390675B2 (en) 1999-10-15 2008-06-24 Christopher Feistel Multi-functional and configurable assay
US6436722B1 (en) 2000-04-18 2002-08-20 Idexx Laboratories, Inc. Device and method for integrated diagnostics with multiple independent flow paths
EP1340085B1 (en) 2000-10-17 2008-07-30 Besst-Test Aps Assay for directly detecting a biological cell in a body fluid sample
US6855561B2 (en) 2001-09-10 2005-02-15 Quidel Corporation Method for adding an apparent non-signal line to a lateral flow assay
US20030215358A1 (en) 2002-01-15 2003-11-20 Schulman Lloyd S. Liquid permeable composition in dry reagent devices
JP3797480B2 (ja) 2002-03-04 2006-07-19 株式会社東北テクノアーチ ネコ腎臓病診断マーカー
US20040002168A1 (en) 2002-06-13 2004-01-01 Neuropro Technologies, Inc. Apparatus and methods for detecting cerebrospinal fluid
US7244394B2 (en) 2002-10-03 2007-07-17 Novartis Ag Methods and kits for assays of analytes of interest in tears
US7459314B2 (en) 2003-02-13 2008-12-02 Inverness Medical Switzerland Gmbh Lateral flow immunoassay controls
WO2004081528A2 (en) 2003-03-10 2004-09-23 Robinson Joseph R Assay device and method
US20070003992A1 (en) 2003-04-09 2007-01-04 Pentyala Srinivas N Methods and kits for detecting cerebrospinal fluid in a sample
US20040203079A1 (en) 2003-04-09 2004-10-14 Research Foundation Of The State University Of New York Methods and kits for detecting cerebrospinal fluid in a sample
US8003765B2 (en) 2003-04-09 2011-08-23 Stony Brook Anaesthesiology, University Faculty Practice Corporation Methods, antibodies and kits for detecting cerebrospinal fluid in a sample
WO2005042579A1 (ja) 2003-10-31 2005-05-12 Fujirebio Inc. 抗ｓａｒｓウイルス抗体、該抗体を産生するハイブリドーマ及び該抗体を用いる免疫測定試薬
WO2005075998A1 (en) 2004-01-29 2005-08-18 Dsm Ip Assets B.V. Improved lateral flow binding assay
US7435577B2 (en) 2004-02-03 2008-10-14 Polymer Technology Systems, Inc. Direct measurement of chlolesterol from low density lipoprotein with test strip
ES2382381T3 (es) * 2004-02-23 2012-06-07 Ethicon, Inc. Sistemas de hisopo y punzón de biopsia para diagnóstico
WO2005098439A2 (en) 2004-03-30 2005-10-20 Whatman, Inc. Lateral flow format, materials and mehtods
DE502004005503D1 (de) * 2004-06-25 2007-12-27 Kuehni Ag Verfahren zur Extraktion von biologischem Material
US20060019406A1 (en) 2004-07-23 2006-01-26 Ning Wei Lateral flow device for the detection of large pathogens
US8445293B2 (en) 2005-02-09 2013-05-21 Rapid Pathogen Screening, Inc. Method to increase specificity and/or accuracy of lateral flow immunoassays
US20060246513A1 (en) 2005-05-02 2006-11-02 Bohannon Robert C Method and device to detect the presence of analytes in a sample
MX2007014476A (es) 2005-05-20 2008-02-07 Calypte Biomedical Corp Prueba de inmunocromatografia rapida de fluido oral.
US7794656B2 (en) 2006-01-23 2010-09-14 Quidel Corporation Device for handling and analysis of a biological sample
WO2007092302A2 (en) 2006-02-07 2007-08-16 Envirologix Inc. Test device for analyte detection
EP2215450B1 (en) 2006-02-21 2013-07-31 Nexus DX, Inc. Methods and compositions for analyte detection
US20090110601A1 (en) 2006-07-09 2009-04-30 Raphael Levi Molecularly imprinted polymers for detection in lateral flow devices
US7749775B2 (en) 2006-10-03 2010-07-06 Jonathan Scott Maher Immunoassay test device and method of use
WO2008043040A2 (en) 2006-10-05 2008-04-10 Massachusetts Institute Of Technology Integrated microfluidic device for preconcentration and detection of multiple biomarkers
CN101578520B (zh) 2006-10-18 2015-09-16 哈佛学院院长等 基于形成图案的多孔介质的横向流动和穿过生物测定装置、及其制备方法和使用方法
JP2010515877A (ja) 2006-10-18 2010-05-13 プレジデント アンド フェロウズ オブ ハーバード カレッジ パターン化多孔質媒体に基づくラテラルフロー式及びフロースルー式バイオアッセイ装置、該装置の製造方法、及び該装置の使用方法
US20080138842A1 (en) 2006-12-11 2008-06-12 Hans Boehringer Indirect lateral flow sandwich assay
KR100902093B1 (ko) 2007-05-23 2009-06-09 인하대학교 산학협력단 미세채널 내에서 가시광선의 투과도 측정을 이용한 액체의Ｄｒｏｐｌｅｔ／Ｐｌｕｇ 및 미세입자 크기와 개수측정장치 및 측정방법
US20100227323A1 (en) 2007-07-30 2010-09-09 Cornell Research Foundation, Inc. Microchannel detection device and use thereof
EP2245135A4 (en) 2007-12-27 2011-01-12 Infigo Diagnostics Ltd ANALYSIS FOR SMALL MOLECULES AND PROTEINS BASED ON MOLECULAR PRESENTED POLYMERS
CN102016595B (zh) 2008-03-27 2014-08-06 哈佛学院院长等 三维微流体装置
CA2723536C (en) 2008-05-05 2017-06-13 Los Alamos National Security, Llc Highly simplified lateral flow-based nucleic acid sample preparation and passive fluid flow control
US20130196310A1 (en) 2008-05-20 2013-08-01 Rapid Pathogen Screening, Inc. Method and Device for Combined Detection of Viral and Bacterial Infections
US20110151479A1 (en) 2008-08-25 2011-06-23 University Of Washington Microfluidic systems incorporating flow-through membranes
US20110257378A1 (en) 2008-11-25 2011-10-20 Ge Healthcare Bio-Sciences Ab Aqueous two phase extraction augmented precipitation process for purification of therapeutic proteins
JP5694922B2 (ja) 2009-04-28 2015-04-01 デンカ生研株式会社 簡易メンブレンアッセイ装置
CA2807645C (en) 2009-08-07 2021-09-07 Affinimark Technologies, Inc. Device and methods for the immunological identification of cerebrospinal fluid
JP5205354B2 (ja) 2009-09-30 2013-06-05 富士フイルム株式会社 クロマトグラフ測定装置
EP2548022B1 (en) 2010-03-18 2016-03-16 The Regents Of The University Of Michigan Multiphase microarrays and uses thereof
US20110312650A1 (en) 2010-06-17 2011-12-22 Geneasys Pty Ltd Microfluidic device with optically transparent hybridization chambers for electrochemiluminescent detection of targets
FR2963108B1 (fr) 2010-07-21 2017-06-23 Diagast Procede magnetique d'immunodiagnostic et kit pour la mise en evidence de complexe anticorps/antigene de groupe/phenotype sanguin
WO2012024690A1 (en) 2010-08-20 2012-02-23 President And Fellows Of Harvard College Multiphase systems having multiple phase properties
DE102011001743A1 (de) 2011-04-01 2012-10-04 Technische Universität Dortmund Verfahren zur Trennung/Reinigung von Biomolekühlen
GB201107466D0 (en) 2011-05-05 2011-06-15 Loktionov Alexandre Device and method for non-invasive collection of colorectal mucocellular layer and disease detection
US9939442B2 (en) 2011-09-08 2018-04-10 The Regents Of The University Of California Salivary biomarkers for gastric cancer detection
CN104040358A (zh) 2011-09-30 2014-09-10 加利福尼亚大学董事会 微流体装置和使用其测定流体样品的方法
EP2788478B1 (en) 2011-12-09 2017-08-23 Institut Pasteur Multiplex immuno screening assay
WO2013105090A1 (en) 2012-01-11 2013-07-18 Aptateck Bio Ltd. A versatile lateral flow strip device
CN102584933A (zh) 2012-02-13 2012-07-18 汪志友 一种利用亲和双水相系统提高凝血因子ⅷ及其类似物分离效率、纯度与生物比活性的方法
JP5917201B2 (ja) 2012-03-02 2016-05-11 田中貴金属工業株式会社 イムノクロマトグラフィー用試験ストリップ
US20140004539A1 (en) * 2012-06-15 2014-01-02 The Regents Of The University Of Michigan Systems and methods for multiplex solution assays
US9310300B2 (en) 2012-08-03 2016-04-12 Ingeneron Incorporated Compact portable apparatus for optical assay
US20160282343A1 (en) 2012-08-15 2016-09-29 Immunolab LLC Quantitative lateral flow assay strips for quantitative analysis of an analyte, kits containing such strips and methods of manufacture and use of same
US20150198592A1 (en) 2012-11-15 2015-07-16 Daniel Wang Rapid Lateral Flow Assay Method for Low Quantity Liquid or Dry Samples
US20150017656A1 (en) 2012-11-15 2015-01-15 Daniel Wang Rapid Lateral Flow Assay Method for Detecting Low Quantity Liquid or Dry Samples
CN103008038B (zh) 2013-01-11 2015-07-01 西安交通大学 双极电极-纸基微流控的芯片及其制备方法
CN103808926B (zh) 2014-01-14 2016-08-17 中国科学院生物物理研究所 纳米模拟酶免疫层析检测方法
KR102630880B1 (ko) 2014-03-07 2024-01-29 더 리전트 오브 더 유니버시티 오브 캘리포니아 분석물 추출, 농축 및 검출을 통합하기 위한 장치
US20160313307A1 (en) 2015-04-23 2016-10-27 Ted Titmus Diagnostic test strip for oral samples and method of use therefore
CN107850548A (zh) 2015-06-18 2018-03-27 神经外科公司 脑脊液的检测
WO2017041030A1 (en) 2015-09-04 2017-03-09 The Regents Of The University Of California Methods and devices for analyte collection, extraction, concentration, and detection for clinical applications
US20170323441A1 (en) 2016-05-09 2017-11-09 University Of Washington Filter-free devices and systems for measuring fluorescence of a microfluidic assay and associated methods of use
EP4202439B1 (en) 2016-06-09 2025-02-19 The Regents of the University of California Method of purifying and amplifying a nucleic acid
WO2018013697A2 (en) 2016-07-12 2018-01-18 Purdue Research Foundation Devices systems, and methods for the detection of a target analyte using magnetic focus lateral flow immunoassay techniques
US11327075B2 (en) 2016-08-22 2022-05-10 The Regents Of The University Of California Hydrogel platform for aqueous two-phase concentration of a target to enhance its detection
US11209427B2 (en) 2017-03-27 2021-12-28 The Regents Of The University Of California Semi-quantitative lateral-flow immunoassay for the detection of CSF leaks
EP3635400A4 (en) 2017-05-31 2021-02-24 The Regents of The University of California SINGLE-LEVEL, ATPS-EXTENDED LFA DIAGNOSTIC DESIGN

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011159537A2 (en) * 2010-06-15 2011-12-22 The Regents Of The University Of California Method and device for analyte detection
US20120238008A1 (en) * 2011-03-15 2012-09-20 Colorado State University Research Foundation Rapid Detection of Pathogens Using Paper Devices

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
F MASHAYEKHI ET AL: "Enhancing the lateral-flow immunoassay for viral detction using an aqueous two-phase micellar system", ANALYTICAL BIOANALYTICAL CHEMISTRY, vol. 398, JPN6020032687, 24 September 2010 (2010-09-24), pages 2955 - 2961, ISSN: 0004581250 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022154826A (ja) * 2021-03-30 2022-10-13 東洋紡株式会社 ビタミンａの定量方法
JP7619128B2 (ja) 2021-03-30 2025-01-22 東洋紡株式会社 ビタミンａの定量方法

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