JP2018534536A5 - - Google Patents
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- JP2018534536A5 JP2018534536A5 JP2018511707A JP2018511707A JP2018534536A5 JP 2018534536 A5 JP2018534536 A5 JP 2018534536A5 JP 2018511707 A JP2018511707 A JP 2018511707A JP 2018511707 A JP2018511707 A JP 2018511707A JP 2018534536 A5 JP2018534536 A5 JP 2018534536A5
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- JP
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- Prior art keywords
- phase solution
- bacteria
- sample
- polymer
- bacterium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 241000894006 Bacteria Species 0.000 claims 37
- 239000000523 sample Substances 0.000 claims 36
- 241000233866 Fungi Species 0.000 claims 17
- 241000700605 Viruses Species 0.000 claims 17
- 229920000642 polymer Polymers 0.000 claims 13
- 239000004094 surface-active agent Substances 0.000 claims 10
- 238000001514 detection method Methods 0.000 claims 7
- 239000011248 coating agent Substances 0.000 claims 6
- 238000000576 coating method Methods 0.000 claims 6
- 239000012530 fluid Substances 0.000 claims 6
- 238000005303 weighing Methods 0.000 claims 6
- -1 polyethylene Polymers 0.000 claims 5
- 229920002307 Dextran Polymers 0.000 claims 4
- 239000002202 Polyethylene glycol Substances 0.000 claims 4
- 238000003556 assay Methods 0.000 claims 4
- 229920001223 polyethylene glycol Polymers 0.000 claims 4
- 229920001451 polypropylene glycol Polymers 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 4
- 210000002700 urine Anatomy 0.000 claims 4
- 241000194019 Streptococcus mutans Species 0.000 claims 3
- 210000003679 cervix uteri Anatomy 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 239000002105 nanoparticle Substances 0.000 claims 3
- 241001147825 Actinomyces sp. Species 0.000 claims 2
- 241001495184 Chlamydia sp. Species 0.000 claims 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 2
- 241000711827 Gardnerella sp. Species 0.000 claims 2
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 claims 2
- 241001440871 Neisseria sp. Species 0.000 claims 2
- 239000004743 Polypropylene Substances 0.000 claims 2
- 241000589906 Treponema sp. Species 0.000 claims 2
- 241000220979 Trichomonas sp. Species 0.000 claims 2
- 230000007613 environmental effect Effects 0.000 claims 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims 2
- 229910052737 gold Inorganic materials 0.000 claims 2
- 239000010931 gold Substances 0.000 claims 2
- 239000000693 micelle Substances 0.000 claims 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 239000000376 reactant Substances 0.000 claims 2
- 229910052709 silver Inorganic materials 0.000 claims 2
- 239000004332 silver Substances 0.000 claims 2
- LWIHDJKSTIGBAC-UHFFFAOYSA-K tripotassium phosphate Chemical group [K+].[K+].[K+].[O-]P([O-])([O-])=O LWIHDJKSTIGBAC-UHFFFAOYSA-K 0.000 claims 2
- 241000589158 Agrobacterium Species 0.000 claims 1
- 241000606125 Bacteroides Species 0.000 claims 1
- 241000222122 Candida albicans Species 0.000 claims 1
- 229920002101 Chitin Polymers 0.000 claims 1
- 108010092160 Dactinomycin Proteins 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 241000588724 Escherichia coli Species 0.000 claims 1
- 102000003886 Glycoproteins Human genes 0.000 claims 1
- 108090000288 Glycoproteins Proteins 0.000 claims 1
- 240000001046 Lactobacillus acidophilus Species 0.000 claims 1
- 235000013956 Lactobacillus acidophilus Nutrition 0.000 claims 1
- 244000199866 Lactobacillus casei Species 0.000 claims 1
- 235000013958 Lactobacillus casei Nutrition 0.000 claims 1
- 102000004856 Lectins Human genes 0.000 claims 1
- 108090001090 Lectins Proteins 0.000 claims 1
- 239000004677 Nylon Substances 0.000 claims 1
- 229930040373 Paraformaldehyde Natural products 0.000 claims 1
- 239000004698 Polyethylene Substances 0.000 claims 1
- 241001300940 Porphyromonas sp. Species 0.000 claims 1
- 241000611831 Prevotella sp. Species 0.000 claims 1
- 241000334216 Proteus sp. Species 0.000 claims 1
- 102000007562 Serum Albumin Human genes 0.000 claims 1
- 108010071390 Serum Albumin Proteins 0.000 claims 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims 1
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 claims 1
- 241000191967 Staphylococcus aureus Species 0.000 claims 1
- 241000194022 Streptococcus sp. Species 0.000 claims 1
- 239000002250 absorbent Substances 0.000 claims 1
- 230000002745 absorbent Effects 0.000 claims 1
- 229930183665 actinomycin Natural products 0.000 claims 1
- 239000013543 active substance Substances 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- BIGPRXCJEDHCLP-UHFFFAOYSA-N ammonium bisulfate Chemical compound [NH4+].OS([O-])(=O)=O BIGPRXCJEDHCLP-UHFFFAOYSA-N 0.000 claims 1
- 239000012491 analyte Substances 0.000 claims 1
- 150000004945 aromatic hydrocarbons Chemical class 0.000 claims 1
- 239000012472 biological sample Substances 0.000 claims 1
- 229920001222 biopolymer Polymers 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 229940095731 candida albicans Drugs 0.000 claims 1
- 229920002678 cellulose Polymers 0.000 claims 1
- 239000001913 cellulose Substances 0.000 claims 1
- 239000000919 ceramic Substances 0.000 claims 1
- 238000012875 competitive assay Methods 0.000 claims 1
- 230000014670 detection of bacterium Effects 0.000 claims 1
- 230000002708 enhancing effect Effects 0.000 claims 1
- 239000011521 glass Substances 0.000 claims 1
- 229920013746 hydrophilic polyethylene oxide Polymers 0.000 claims 1
- 125000001165 hydrophobic group Chemical group 0.000 claims 1
- 229910052500 inorganic mineral Inorganic materials 0.000 claims 1
- 229940039695 lactobacillus acidophilus Drugs 0.000 claims 1
- 229940017800 lactobacillus casei Drugs 0.000 claims 1
- 239000002523 lectin Substances 0.000 claims 1
- 150000002632 lipids Chemical class 0.000 claims 1
- 229910052943 magnesium sulfate Inorganic materials 0.000 claims 1
- 235000019341 magnesium sulphate Nutrition 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- 229910052751 metal Inorganic materials 0.000 claims 1
- 239000002184 metal Substances 0.000 claims 1
- 239000011707 mineral Substances 0.000 claims 1
- 235000010755 mineral Nutrition 0.000 claims 1
- 239000002736 nonionic surfactant Substances 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 229920001778 nylon Polymers 0.000 claims 1
- 229920002113 octoxynol Polymers 0.000 claims 1
- 239000004033 plastic Substances 0.000 claims 1
- 229920003023 plastic Polymers 0.000 claims 1
- 229910052697 platinum Inorganic materials 0.000 claims 1
- 229920000573 polyethylene Polymers 0.000 claims 1
- 229920000151 polyglycol Polymers 0.000 claims 1
- 239000010695 polyglycol Substances 0.000 claims 1
- 229920006324 polyoxymethylene Polymers 0.000 claims 1
- 229920001155 polypropylene Polymers 0.000 claims 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 claims 1
- 239000004810 polytetrafluoroethylene Substances 0.000 claims 1
- 229920000915 polyvinyl chloride Polymers 0.000 claims 1
- 239000004800 polyvinyl chloride Substances 0.000 claims 1
- 229910000160 potassium phosphate Inorganic materials 0.000 claims 1
- 235000011009 potassium phosphates Nutrition 0.000 claims 1
- 239000010453 quartz Substances 0.000 claims 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 1
- 150000003384 small molecules Chemical class 0.000 claims 1
- 239000001509 sodium citrate Substances 0.000 claims 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims 1
- 229910052938 sodium sulfate Inorganic materials 0.000 claims 1
- 235000011152 sodium sulphate Nutrition 0.000 claims 1
- 239000000758 substrate Substances 0.000 claims 1
- 229920001059 synthetic polymer Polymers 0.000 claims 1
- 235000021419 vinegar Nutrition 0.000 claims 1
- 239000000052 vinegar Substances 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022028070A JP7399994B2 (ja) | 2015-09-04 | 2022-02-25 | 臨床上の用途のための、分析物の収集、抽出、濃縮、及び検出のための方法及び装置 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562214801P | 2015-09-04 | 2015-09-04 | |
| US62/214,801 | 2015-09-04 | ||
| PCT/US2016/050257 WO2017041030A1 (en) | 2015-09-04 | 2016-09-02 | Methods and devices for analyte collection, extraction, concentration, and detection for clinical applications |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022028070A Division JP7399994B2 (ja) | 2015-09-04 | 2022-02-25 | 臨床上の用途のための、分析物の収集、抽出、濃縮、及び検出のための方法及び装置 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018534536A JP2018534536A (ja) | 2018-11-22 |
| JP2018534536A5 true JP2018534536A5 (enExample) | 2019-10-10 |
Family
ID=58188570
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018511707A Pending JP2018534536A (ja) | 2015-09-04 | 2016-09-02 | 臨床上の用途のための、分析物の収集、抽出、濃縮、及び検出のための方法及び装置 |
| JP2022028070A Active JP7399994B2 (ja) | 2015-09-04 | 2022-02-25 | 臨床上の用途のための、分析物の収集、抽出、濃縮、及び検出のための方法及び装置 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022028070A Active JP7399994B2 (ja) | 2015-09-04 | 2022-02-25 | 臨床上の用途のための、分析物の収集、抽出、濃縮、及び検出のための方法及び装置 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US11287426B2 (enExample) |
| EP (1) | EP3345001A4 (enExample) |
| JP (2) | JP2018534536A (enExample) |
| KR (1) | KR102693068B1 (enExample) |
| CN (1) | CN108139402B (enExample) |
| AU (1) | AU2016318103B2 (enExample) |
| CA (1) | CA3002020C (enExample) |
| HK (1) | HK1257999A1 (enExample) |
| WO (1) | WO2017041030A1 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102630880B1 (ko) | 2014-03-07 | 2024-01-29 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | 분석물 추출, 농축 및 검출을 통합하기 위한 장치 |
| WO2017041030A1 (en) | 2015-09-04 | 2017-03-09 | The Regents Of The University Of California | Methods and devices for analyte collection, extraction, concentration, and detection for clinical applications |
| EP4202439B1 (en) | 2016-06-09 | 2025-02-19 | The Regents of the University of California | Method of purifying and amplifying a nucleic acid |
| US11327075B2 (en) | 2016-08-22 | 2022-05-10 | The Regents Of The University Of California | Hydrogel platform for aqueous two-phase concentration of a target to enhance its detection |
| JP7145517B2 (ja) | 2017-03-08 | 2022-10-03 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 分析物の検出 |
| US11209427B2 (en) | 2017-03-27 | 2021-12-28 | The Regents Of The University Of California | Semi-quantitative lateral-flow immunoassay for the detection of CSF leaks |
| WO2018183454A1 (en) * | 2017-03-28 | 2018-10-04 | Chiu Yin To | Method and device for accurate diagnosis of dental diseases |
| CN110462400B (zh) | 2017-03-28 | 2022-06-21 | 相达生物科技国际有限公司 | 用于在液体活检中准确诊断疾病靶向生物标记的方法 |
| EP3635400A4 (en) * | 2017-05-31 | 2021-02-24 | The Regents of The University of California | SINGLE-LEVEL, ATPS-EXTENDED LFA DIAGNOSTIC DESIGN |
| CN119425158A (zh) | 2017-06-01 | 2025-02-14 | 相达生物科技美国有限公司 | 用于多孔材料中双水相分离的相分离行为改性剂 |
| US11609232B2 (en) | 2017-09-01 | 2023-03-21 | Phase Diagnostics, Inc. | Method and device of using aqueous two-phase systems (ATPS) for enhancing diagnostics for sexually transmitted infections |
| US20200318153A1 (en) * | 2017-09-01 | 2020-10-08 | Phase Diagnostics, Inc. | Method and device of using aqueous two-phase systems (ATPS) for enhancing diagnostics for dental and oral diseases |
| JP7323532B2 (ja) * | 2017-09-18 | 2023-08-08 | フェーズ サイエンティフィック インターナショナル リミテッド | 短い核酸断片の単離、精製及び／又は濃縮のために水性二相系を使用する方法 |
| WO2019118705A1 (en) * | 2017-12-14 | 2019-06-20 | The Regents Of The University Of Michigan | Concentration of analytes |
| WO2019118712A1 (en) * | 2017-12-14 | 2019-06-20 | Yin To Chiu | One-step isolation, concentration and/or purification of nucleic acids using atps-embedded microfluidic device |
| WO2019143943A2 (en) | 2018-01-19 | 2019-07-25 | Yin To Chiu | Composition and method for concentration and enrichment of nucleic acids |
| US12043826B2 (en) | 2018-01-19 | 2024-07-23 | Phase Scientific International, Ltd. | Spontaneous nucleic acid purification and concentration in a single step |
| US11643646B2 (en) | 2018-01-19 | 2023-05-09 | Phase Scientific International, Ltd. | Method for isolating and purifying nucleic acids using a solid-liquid phase system |
| WO2019144016A1 (en) | 2018-01-19 | 2019-07-25 | Yin To Chiu | Method of isolating exosomes using encapsulation and aqueous micellar system |
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| US20230201824A1 (en) * | 2020-08-17 | 2023-06-29 | University Of Washington | Long-term dry storage of enzyme-based reagents in a porous matrix |
| CN112881700A (zh) * | 2021-01-12 | 2021-06-01 | 瑞吉瑞得医药生物科技(无锡)有限公司 | 一种用于全血样本预处理的磷酸盐缓冲液及其使用方法 |
| US12144493B2 (en) * | 2021-03-24 | 2024-11-19 | National Defense Medical Center | Collection and test device for rapid test |
| JP7619128B2 (ja) * | 2021-03-30 | 2025-01-22 | 東洋紡株式会社 | ビタミンａの定量方法 |
| CN113189347A (zh) * | 2021-05-12 | 2021-07-30 | 瑞吉瑞得医药生物科技(无锡)有限公司 | 一种用于老年痴呆病血清中A-beta抗原检测的胶体金试纸及其使用方法 |
| US20240255395A1 (en) * | 2021-06-03 | 2024-08-01 | Regents Of The University Of Minnesota | Methods, devices and systems for separating biological analytes from samples |
| CN119137270A (zh) | 2022-11-02 | 2024-12-13 | 相达生物科技国际有限公司 | 使用atps和固相介质从生物样品分离目标分析物的方法 |
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-
2016
- 2016-09-02 WO PCT/US2016/050257 patent/WO2017041030A1/en not_active Ceased
- 2016-09-02 US US15/756,542 patent/US11287426B2/en active Active
- 2016-09-02 CA CA3002020A patent/CA3002020C/en active Active
- 2016-09-02 HK HK19100366.5A patent/HK1257999A1/zh unknown
- 2016-09-02 EP EP16843134.4A patent/EP3345001A4/en not_active Withdrawn
- 2016-09-02 CN CN201680059385.6A patent/CN108139402B/zh active Active
- 2016-09-02 AU AU2016318103A patent/AU2016318103B2/en active Active
- 2016-09-02 KR KR1020187009424A patent/KR102693068B1/ko active Active
- 2016-09-02 JP JP2018511707A patent/JP2018534536A/ja active Pending
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2022
- 2022-02-16 US US17/673,530 patent/US11885803B2/en active Active
- 2022-02-25 JP JP2022028070A patent/JP7399994B2/ja active Active
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