JP2018534288A5 - - Google Patents

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Publication number
JP2018534288A5
JP2018534288A5 JP2018519487A JP2018519487A JP2018534288A5 JP 2018534288 A5 JP2018534288 A5 JP 2018534288A5 JP 2018519487 A JP2018519487 A JP 2018519487A JP 2018519487 A JP2018519487 A JP 2018519487A JP 2018534288 A5 JP2018534288 A5 JP 2018534288A5
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
amount
cytarabine
aml
administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2018519487A
Other languages
English (en)
Japanese (ja)
Other versions
JP2018534288A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2016/057083 external-priority patent/WO2017066599A1/en
Publication of JP2018534288A publication Critical patent/JP2018534288A/ja
Publication of JP2018534288A5 publication Critical patent/JP2018534288A5/ja
Priority to JP2021087311A priority Critical patent/JP2021130682A/ja
Withdrawn legal-status Critical Current

Links

JP2018519487A 2015-10-15 2016-10-14 悪性腫瘍の治療のための併用療法 Withdrawn JP2018534288A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021087311A JP2021130682A (ja) 2015-10-15 2021-05-25 悪性腫瘍の治療のための併用療法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562242256P 2015-10-15 2015-10-15
US62/242,256 2015-10-15
US201562255194P 2015-11-13 2015-11-13
US62/255,194 2015-11-13
PCT/US2016/057083 WO2017066599A1 (en) 2015-10-15 2016-10-14 Combination therapy for treating malignancies

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021087311A Division JP2021130682A (ja) 2015-10-15 2021-05-25 悪性腫瘍の治療のための併用療法

Publications (2)

Publication Number Publication Date
JP2018534288A JP2018534288A (ja) 2018-11-22
JP2018534288A5 true JP2018534288A5 (enExample) 2019-11-28

Family

ID=57208385

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2018519487A Withdrawn JP2018534288A (ja) 2015-10-15 2016-10-14 悪性腫瘍の治療のための併用療法
JP2021087311A Pending JP2021130682A (ja) 2015-10-15 2021-05-25 悪性腫瘍の治療のための併用療法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2021087311A Pending JP2021130682A (ja) 2015-10-15 2021-05-25 悪性腫瘍の治療のための併用療法

Country Status (15)

Country Link
US (2) US10905692B2 (enExample)
EP (2) EP4147692A1 (enExample)
JP (2) JP2018534288A (enExample)
KR (2) KR20180063125A (enExample)
CN (1) CN108366980A (enExample)
AU (1) AU2016340087C1 (enExample)
BR (1) BR112018007304A2 (enExample)
CA (1) CA3001599A1 (enExample)
CL (1) CL2018000927A1 (enExample)
EA (1) EA201890968A1 (enExample)
IL (2) IL311873A (enExample)
MX (2) MX394796B (enExample)
SG (1) SG10201912886XA (enExample)
WO (1) WO2017066599A1 (enExample)
ZA (1) ZA201802088B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3200800A1 (en) 2014-09-29 2017-08-09 Agios Pharmaceuticals, Inc. Therapeutically active compounds and their methods of use
WO2016126798A1 (en) 2015-02-04 2016-08-11 Agios Pharmaceuticals, Inc. Therapeutically active compounds and their methods of use
MX381582B (es) 2015-10-15 2025-03-12 Celgene Corp Terapia de combinacion para el tratamiento de neoplasias malignas.
US12064445B2 (en) 2015-12-03 2024-08-20 Biosight Ltd. Cytarabine conjugates for cancer therapy
JP2019529534A (ja) 2016-09-07 2019-10-17 セルジーン コーポレイション 錠剤組成物
EP3618828B1 (en) 2017-05-05 2023-11-01 Memorial Sloan Kettering Cancer Center Methods of treatment of myeloproliferative neoplasm
WO2019012328A1 (en) * 2017-07-09 2019-01-17 Biosight Pharma ANTICANCER POLY THERAPY
US10980788B2 (en) * 2018-06-08 2021-04-20 Agios Pharmaceuticals, Inc. Therapy for treating malignancies
US20220017490A1 (en) 2018-11-02 2022-01-20 Celgene Corporation Co-crystals of 2-methyl-1 -[(4-[6-(trifluoromethyl)pyridin-2-yl]-6-{[2-(trifluoromethyl) pyridin-4-yl]amino}-1,3,5-triazin-2-yl)amino]propan-2-ol, compositions and methods of use thereof
US20220017489A1 (en) 2018-11-02 2022-01-20 Celgene Corporation Solid dispersions for treatment of cancer
US12215094B2 (en) 2018-11-02 2025-02-04 Celgene Corporation Solid forms of 2-methyl-1-[(4-[6-(trifluoromethyl)pyridin-2-yl]-6-{[2-(trifluoromethyl)pyridin-4-yl]amino}-1,3,5-triazin-2-yl) amino]propan-2-ol
WO2021097160A1 (en) 2019-11-14 2021-05-20 Celgene Corporation Pediatric formulations for treatment of cancer
CN111087408B (zh) * 2020-01-03 2021-04-02 浙江大学 一种大环结构的idh2突变体抑制剂及其医药用途

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2248908T7 (es) 1997-06-06 2014-11-24 Depomed, Inc. Formas de dosificación de fármacos por vía oral y retención gástrica para liberación continuada de fármacos altamente solubles
US6635280B2 (en) 1997-06-06 2003-10-21 Depomed, Inc. Extending the duration of drug release within the stomach during the fed mode
PT1251832E (pt) 2000-02-04 2007-01-31 Depomed Inc Forma de dosagem constituída por invólucro-e-núcleo que conduz a uma libertação do fármaco de ordem zero
US6723340B2 (en) 2001-10-25 2004-04-20 Depomed, Inc. Optimal polymer mixtures for gastric retentive tablets
ES2740424T3 (es) 2009-03-13 2020-02-05 Agios Pharmaceuticals Inc Métodos y composiciones para trastornos relacionados con la proliferación celular
EP2525790B1 (en) 2009-10-21 2020-05-27 Agios Pharmaceuticals, Inc. Methods and compositions for cell-proliferation-related disorders
LT2800743T (lt) 2012-01-06 2018-06-25 Agios Pharmaceuticals, Inc. Terapiškai aktyvūs junginiai ir jų panaudojimo būdai
ES2807582T3 (es) 2013-07-11 2021-02-23 Agios Pharmaceuticals Inc Compuestos N,6-bis(aril o heteroaril)-1,3,5-triazina-2,4-diamina como inhibidores de mutantes IDH2 para el tratamiento del cáncer
WO2015018060A1 (en) 2013-08-09 2015-02-12 Agios Pharmaceuticals, Inc. Crystalline forms of therapeutically active compounds and use thereof
WO2015017821A2 (en) 2013-08-02 2015-02-05 Agios Pharmaceuticals, Inc. Therapeutically active compounds and their methods of use
EP3200800A1 (en) 2014-09-29 2017-08-09 Agios Pharmaceuticals, Inc. Therapeutically active compounds and their methods of use
WO2016126798A1 (en) 2015-02-04 2016-08-11 Agios Pharmaceuticals, Inc. Therapeutically active compounds and their methods of use
EP3331866B1 (en) 2015-08-05 2023-07-26 Les Laboratoires Servier Methods of preparing a 6-heteroaryl-1,3,5-triazine-2,4-diol and a 6-heteroaryl-1,3,5-triazine-2,4-diamine
MX381582B (es) 2015-10-15 2025-03-12 Celgene Corp Terapia de combinacion para el tratamiento de neoplasias malignas.
IL298663A (en) 2015-12-04 2023-01-01 Agios Pharmaceuticals Inc Methods for treating acute myeloid leukemia characterized by the presence of a mutant allele of idh2 and the absence of a mutant allele of nras
WO2017146795A1 (en) 2016-02-26 2017-08-31 Agios Pharmaceuticals, Inc. Idh1 inhibitors for the treatment of haematological malignancies and solid tumours

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