JP2018523483A5 - - Google Patents

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Publication number
JP2018523483A5
JP2018523483A5 JP2018509494A JP2018509494A JP2018523483A5 JP 2018523483 A5 JP2018523483 A5 JP 2018523483A5 JP 2018509494 A JP2018509494 A JP 2018509494A JP 2018509494 A JP2018509494 A JP 2018509494A JP 2018523483 A5 JP2018523483 A5 JP 2018523483A5
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JP
Japan
Prior art keywords
polypeptide
medicament
fusion polypeptide
amino acid
medicament according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2018509494A
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English (en)
Japanese (ja)
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JP6859320B2 (ja
JP2018523483A (ja
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Publication date
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Priority claimed from PCT/EP2016/069680 external-priority patent/WO2017029389A1/en
Publication of JP2018523483A publication Critical patent/JP2018523483A/ja
Publication of JP2018523483A5 publication Critical patent/JP2018523483A5/ja
Application granted granted Critical
Publication of JP6859320B2 publication Critical patent/JP6859320B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2018509494A 2015-08-20 2016-08-19 臓器不全の治療および予防用のb7−h1融合ポリペプチド Active JP6859320B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15181800 2015-08-20
EP15181800.2 2015-08-20
PCT/EP2016/069680 WO2017029389A1 (en) 2015-08-20 2016-08-19 B7-h1 fusion polypeptides for treating and preventing organ failure

Publications (3)

Publication Number Publication Date
JP2018523483A JP2018523483A (ja) 2018-08-23
JP2018523483A5 true JP2018523483A5 (enExample) 2019-09-26
JP6859320B2 JP6859320B2 (ja) 2021-04-14

Family

ID=54014503

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018509494A Active JP6859320B2 (ja) 2015-08-20 2016-08-19 臓器不全の治療および予防用のb7−h1融合ポリペプチド

Country Status (7)

Country Link
US (2) US10632174B2 (enExample)
EP (1) EP3337496B1 (enExample)
JP (1) JP6859320B2 (enExample)
CN (2) CN107921093B (enExample)
CA (1) CA2995987C (enExample)
ES (1) ES2851474T3 (enExample)
WO (1) WO2017029389A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3283508B1 (en) 2015-04-17 2021-03-17 Alpine Immune Sciences, Inc. Immunomodulatory proteins with tunable affinities
US11078282B2 (en) 2016-04-15 2021-08-03 Alpine Immune Sciences, Inc. CD80 variant immunomodulatory proteins and uses thereof
US11471488B2 (en) 2016-07-28 2022-10-18 Alpine Immune Sciences, Inc. CD155 variant immunomodulatory proteins and uses thereof
US11834490B2 (en) 2016-07-28 2023-12-05 Alpine Immune Sciences, Inc. CD112 variant immunomodulatory proteins and uses thereof
CN110662758A (zh) 2017-03-16 2020-01-07 高山免疫科学股份有限公司 Cd80变体免疫调节蛋白及其用途
KR102692556B1 (ko) * 2017-03-16 2024-08-09 알파인 이뮨 사이언시즈, 인코포레이티드 Pd-l1 변이체 면역조절 단백질 및 그의 용도
WO2018170023A1 (en) 2017-03-16 2018-09-20 Alpine Immune Sciences, Inc. Pd-l2 variant immunomodulatory proteins and uses thereof
BR112020013236A2 (pt) 2018-01-03 2020-12-01 Alpine Immune Sciences, Inc. proteínas imunomoduladoras de múltiplos domínios e métodos de seu uso
EP3887394A2 (en) 2018-11-30 2021-10-06 Alpine Immune Sciences, Inc. Cd86 variant immunomodulatory proteins and uses thereof
US10650210B1 (en) 2019-03-18 2020-05-12 Haier Us Appliance Solutions, Inc. Method for authenticating a filter cartridge for a refrigerator appliance
WO2021219807A1 (en) 2020-04-30 2021-11-04 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Pd-l1 variants with improved affinity towards pd-1
TW202208395A (zh) 2020-05-12 2022-03-01 美商信號生物製藥公司 多聚體t細胞調節多肽及其使用方法
JP2023541366A (ja) * 2020-09-09 2023-10-02 キュー バイオファーマ, インコーポレイテッド 1型真性糖尿病(t1d)を治療するためのmhcクラスii t細胞調節多量体ポリペプチド及びその使用方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9657082B2 (en) * 2013-01-31 2017-05-23 Thomas Jefferson University PD-L1 and PD-L2-based fusion proteins and uses thereof
EP3052131B1 (en) * 2013-10-01 2018-12-05 Mayo Foundation for Medical Education and Research Methods for treating cancer in patients with elevated levels of bim

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