JP2017537972A5 - - Google Patents
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- JP2017537972A5 JP2017537972A5 JP2017538182A JP2017538182A JP2017537972A5 JP 2017537972 A5 JP2017537972 A5 JP 2017537972A5 JP 2017538182 A JP2017538182 A JP 2017538182A JP 2017538182 A JP2017538182 A JP 2017538182A JP 2017537972 A5 JP2017537972 A5 JP 2017537972A5
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- JP
- Japan
- Prior art keywords
- cancer
- antibody
- seq
- pharmaceutical composition
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462060381P | 2014-10-06 | 2014-10-06 | |
| US62/060,381 | 2014-10-06 | ||
| PCT/US2015/054202 WO2016057488A1 (en) | 2014-10-06 | 2015-10-06 | Humanized cc chemokine receptor 4 (ccr4) antibodies and methods of use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020138331A Division JP7129449B2 (ja) | 2014-10-06 | 2020-08-19 | ヒト化ｃｃケモカイン受容体４（ｃｃｒ４）抗体およびその使用法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017537972A JP2017537972A (ja) | 2017-12-21 |
| JP2017537972A5 true JP2017537972A5 (enExample) | 2018-11-15 |
| JP6795505B2 JP6795505B2 (ja) | 2020-12-02 |
Family
ID=54337425
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017538182A Active JP6795505B2 (ja) | 2014-10-06 | 2015-10-06 | ヒト化ｃｃケモカイン受容体４（ｃｃｒ４）抗体およびその使用法 |
| JP2020138331A Active JP7129449B2 (ja) | 2014-10-06 | 2020-08-19 | ヒト化ｃｃケモカイン受容体４（ｃｃｒ４）抗体およびその使用法 |
| JP2022131610A Active JP7589204B2 (ja) | 2014-10-06 | 2022-08-22 | ヒト化ｃｃケモカイン受容体４（ｃｃｒ４）抗体およびその使用法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020138331A Active JP7129449B2 (ja) | 2014-10-06 | 2020-08-19 | ヒト化ｃｃケモカイン受容体４（ｃｃｒ４）抗体およびその使用法 |
| JP2022131610A Active JP7589204B2 (ja) | 2014-10-06 | 2022-08-22 | ヒト化ｃｃケモカイン受容体４（ｃｃｒ４）抗体およびその使用法 |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US10675349B2 (enExample) |
| EP (2) | EP3204418B1 (enExample) |
| JP (3) | JP6795505B2 (enExample) |
| CN (2) | CN107250160B (enExample) |
| AU (2) | AU2015328273B2 (enExample) |
| CA (1) | CA2962949C (enExample) |
| WO (1) | WO2016057488A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3204418B1 (en) * | 2014-10-06 | 2020-03-25 | Dana Farber Cancer Institute, Inc. | Humanized cc chemokine receptor 4 (ccr4) antibodies and methods of use thereof |
| EP3233900A2 (en) | 2014-12-19 | 2017-10-25 | Dana-Farber Cancer Institute, Inc. | Chimeric antigen receptors and methods of use thereof |
| JP6956639B2 (ja) | 2015-05-01 | 2021-11-02 | デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド | 抗ｃｃｒ４抗体を用いてサイトカイン発現を媒介する方法 |
| RU2769282C2 (ru) | 2016-06-20 | 2022-03-30 | Кимаб Лимитед | Анти-PD-L1 и IL-2 цитокины |
| WO2018039754A1 (pt) * | 2016-09-01 | 2018-03-08 | Bebeachibuli Romeo | Formulação à base de fatores alimentares, produtos obtidos com o uso da formulação e processos de obtenção |
| CN120795163A (zh) | 2016-10-14 | 2025-10-17 | 丹娜法伯癌症研究所公司 | 模块化四聚体双特异性抗体平台 |
| EP3706750A1 (en) | 2017-11-06 | 2020-09-16 | RAPT Therapeutics, Inc. | Chemokine receptor modulators for treatment of epstein barr virus positive cancer |
| CN108250290B (zh) * | 2018-02-23 | 2024-03-12 | 上海捌加壹医药科技有限公司 | Ccr4的n端重组蛋白及其用途 |
| AU2019235900B2 (en) | 2018-03-14 | 2025-12-11 | Dana-Farber Cancer Institute, Inc. | Engineered cells, T cell immune modulating antibodies and methods for using the same |
| JP7277255B2 (ja) * | 2018-05-31 | 2023-05-18 | 佳寛 大矢 | インビトロでの制御性ｔ細胞の特異性評価方法 |
| CA3119644A1 (en) | 2018-11-30 | 2020-06-04 | Dana-Farber Cancer Institute, Inc. | Chimeric antigen receptor factories and methods of use thereof |
| EP3927731A4 (en) * | 2019-02-19 | 2022-12-28 | The Regents of the University of Colorado, a body corporate | BISPECIFIC IMMUNOTOXINS FOR TARGETING HUMAN CD25S-CCR4+ TUMORS AND REGULATORY T-CELLS |
| KR102910874B1 (ko) * | 2019-03-29 | 2026-01-09 | 유니베르시태트 취리히 | 구획, 특히 cns로의 국소 전달을 위한 fc 변형 생물학적 제제 |
| CN114051532A (zh) * | 2019-05-24 | 2022-02-15 | 希望之城公司 | 用于治疗ccr4阳性恶性肿瘤的经ccr4靶向性嵌合抗原受体修饰的t细胞 |
| EP3983447A4 (en) | 2019-06-14 | 2023-06-28 | Dana-Farber Cancer Institute, Inc. | Antibodies against muc1 and methods of use thereof |
| CN111704668B (zh) * | 2020-06-27 | 2021-03-30 | 天津金域医学检验实验室有限公司 | 抗ccr4抗体及其在治疗癌症中的应用 |
| JP2024508207A (ja) | 2020-12-02 | 2024-02-26 | ブイアイビー ブイゼットダブリュ | がんに対する組み合わせ治療におけるｌｔｂｒアゴニスト |
| WO2025145207A1 (en) | 2023-12-29 | 2025-07-03 | Bristol-Myers Squibb Company | Combination therapy of kras inhibitor and treg-depleting agent |
Family Cites Families (43)
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| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| FR2413974A1 (fr) | 1978-01-06 | 1979-08-03 | David Bernard | Sechoir pour feuilles imprimees par serigraphie |
| US4485045A (en) | 1981-07-06 | 1984-11-27 | Research Corporation | Synthetic phosphatidyl cholines useful in forming liposomes |
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4544545A (en) | 1983-06-20 | 1985-10-01 | Trustees University Of Massachusetts | Liposomes containing modified cholesterol for organ targeting |
| GB8426467D0 (en) | 1984-10-19 | 1984-11-28 | Technology Licence Co Ltd | Monoclonal antibodies |
| US4676980A (en) | 1985-09-23 | 1987-06-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Target specific cross-linked heteroantibodies |
| EP0279862B1 (en) | 1986-08-28 | 1993-11-03 | Teijin Limited | Cytocidal antibody complex and process for its preparation |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5091513A (en) | 1987-05-21 | 1992-02-25 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
| US5132405A (en) | 1987-05-21 | 1992-07-21 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| ES2096590T3 (es) | 1989-06-29 | 1997-03-16 | Medarex Inc | Reactivos biespecificos para la terapia del sida. |
| US5013556A (en) | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| DE69120146T2 (de) | 1990-01-12 | 1996-12-12 | Cell Genesys Inc | Erzeugung xenogener antikörper |
| WO1996033735A1 (en) | 1995-04-27 | 1996-10-31 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| WO1992000373A1 (en) | 1990-06-29 | 1992-01-09 | Biosource Genetics Corporation | Melanin production by transformed microorganisms |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| ATE158021T1 (de) | 1990-08-29 | 1997-09-15 | Genpharm Int | Produktion und nützung nicht-menschliche transgentiere zur produktion heterologe antikörper |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| WO1992020373A1 (en) | 1991-05-14 | 1992-11-26 | Repligen Corporation | Heteroconjugate antibodies for treatment of hiv infection |
| EP0666923A1 (en) | 1991-09-05 | 1995-08-16 | The University Of Connecticut | Targeted delivery of poly- or oligonucleotides to cells |
| US5233409A (en) | 1992-02-25 | 1993-08-03 | Schwab Karl W | Color analysis of organic constituents in sedimentary rocks for thermal maturity |
| ES2301158T3 (es) | 1992-07-24 | 2008-06-16 | Amgen Fremont Inc. | Produccion de anticuerpos xenogenicos. |
| DK0752248T3 (da) | 1992-11-13 | 2000-11-13 | Idec Pharma Corp | Terapeutisk anvendelse af kimæriske og radioaktivt mærkede antistoffer mod humant B-lymfocytbegrænset differentieringsantig |
| EP0745134A1 (en) | 1994-02-22 | 1996-12-04 | Danafarber Cancer Institute | Nucleic acid delivery system, method of synthesis and uses thereof |
| WO1996034096A1 (en) | 1995-04-28 | 1996-10-31 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| US5916771A (en) | 1996-10-11 | 1999-06-29 | Abgenix, Inc. | Production of a multimeric protein by cell fusion method |
| US20020029391A1 (en) | 1998-04-15 | 2002-03-07 | Claude Geoffrey Davis | Epitope-driven human antibody production and gene expression profiling |
| ATE402192T1 (de) | 2000-03-03 | 2008-08-15 | Kyowa Hakko Kogyo Kk | Anti-ccr4 antikörper und fragmente davon |
| JP2003208610A (ja) | 2002-01-16 | 2003-07-25 | Noritsu Koki Co Ltd | 画像処理装置、画像処理方法、画像処理プログラム、および画像処理プログラムを記録した記録媒体 |
| US20070172476A1 (en) * | 2005-07-28 | 2007-07-26 | Kyowa Hakko Kogyo Co., Ltd. | Method of treating B-cell neoplasms or Hodgkin's lymphoma |
| WO2009086514A1 (en) * | 2007-12-28 | 2009-07-09 | Dana-Farber Cancer Institute, Inc. | Humanized monoclonal antibodies and methods of use |
| GB0909906D0 (en) * | 2009-06-09 | 2009-07-22 | Affitech As | Antibodies |
| GB201020738D0 (en) * | 2010-12-07 | 2011-01-19 | Affitech Res As | Antibodies |
| EP3511343A1 (en) * | 2012-05-04 | 2019-07-17 | Dana Farber Cancer Institute, Inc. | Affinity matured anti-ccr4 humanized monoclonal antibodies and methods of use |
| US9111624B2 (en) | 2013-03-22 | 2015-08-18 | Katsuyuki Fujita | Semiconductor memory device |
| EP3204418B1 (en) * | 2014-10-06 | 2020-03-25 | Dana Farber Cancer Institute, Inc. | Humanized cc chemokine receptor 4 (ccr4) antibodies and methods of use thereof |
-
2015
- 2015-10-06 EP EP15782195.0A patent/EP3204418B1/en active Active
- 2015-10-06 JP JP2017538182A patent/JP6795505B2/ja active Active
- 2015-10-06 CA CA2962949A patent/CA2962949C/en active Active
- 2015-10-06 CN CN201580066273.9A patent/CN107250160B/zh active Active
- 2015-10-06 WO PCT/US2015/054202 patent/WO2016057488A1/en not_active Ceased
- 2015-10-06 AU AU2015328273A patent/AU2015328273B2/en active Active
- 2015-10-06 US US15/517,108 patent/US10675349B2/en active Active
- 2015-10-06 EP EP20153701.6A patent/EP3699196A1/en active Pending
- 2015-10-06 CN CN202210046788.4A patent/CN114634571A/zh active Pending
-
2020
- 2020-06-02 US US16/890,429 patent/US11723973B2/en active Active
- 2020-08-19 JP JP2020138331A patent/JP7129449B2/ja active Active
- 2020-12-10 AU AU2020286302A patent/AU2020286302B2/en active Active
-
2022
- 2022-08-22 JP JP2022131610A patent/JP7589204B2/ja active Active
-
2023
- 2023-06-22 US US18/213,132 patent/US12337034B2/en active Active
-
2025
- 2025-05-20 US US19/213,611 patent/US20250339521A1/en active Pending
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