JP2018517778A5 - - Google Patents
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- JP2018517778A5 JP2018517778A5 JP2018517499A JP2018517499A JP2018517778A5 JP 2018517778 A5 JP2018517778 A5 JP 2018517778A5 JP 2018517499 A JP2018517499 A JP 2018517499A JP 2018517499 A JP2018517499 A JP 2018517499A JP 2018517778 A5 JP2018517778 A5 JP 2018517778A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- tumor
- virus
- particles
- oncolytic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562182383P | 2015-06-19 | 2015-06-19 | |
| US62/182,383 | 2015-06-19 | ||
| PCT/IB2016/000993 WO2017037523A1 (en) | 2015-06-19 | 2016-06-17 | Compositions and methods for viral embolization |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018517778A JP2018517778A (ja) | 2018-07-05 |
| JP2018517778A5 true JP2018517778A5 (https=) | 2019-07-18 |
| JP6827467B2 JP6827467B2 (ja) | 2021-02-10 |
Family
ID=58186857
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018517499A Active JP6827467B2 (ja) | 2015-06-19 | 2016-06-17 | ウイルス塞栓術のための組成物および方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US10517910B2 (https=) |
| EP (1) | EP3310383B1 (https=) |
| JP (1) | JP6827467B2 (https=) |
| KR (1) | KR102735275B1 (https=) |
| CN (1) | CN108025056B (https=) |
| AU (1) | AU2016313969B2 (https=) |
| ES (1) | ES2795010T3 (https=) |
| WO (1) | WO2017037523A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115300622A (zh) | 2015-02-25 | 2022-11-08 | 纪念斯隆-凯特琳癌症中心 | 使用灭活的修饰的痘苗病毒安卡拉作为实体肿瘤的单一免疫疗法或与免疫检查点阻断剂组合 |
| CN107847534B (zh) | 2015-04-17 | 2022-10-04 | 纪念斯隆凯特琳癌症中心 | Mva或mvaδe3l作为抗实体瘤的免疫治疗剂的应用 |
| JP6827467B2 (ja) | 2015-06-19 | 2021-02-10 | シルラジェン，インコーポレイテッド | ウイルス塞栓術のための組成物および方法 |
| IL261321B2 (en) | 2016-02-25 | 2023-12-01 | Memorial Sloan Kettering Cancer Center | Recombinant mva or mvadele3l expressing human flt3l and use thereof as immuno-therapeutic agents against solid tumors |
| KR20180133395A (ko) | 2016-02-25 | 2018-12-14 | 메모리얼 슬로안 케터링 캔서 센터 | 암 면역요법을 위한, 인간 flt3l 또는 gm-csf의 발현이 있거나 없으며 티미딘 키나제가 결실된 복제 가능 약독화 백시니아 바이러스 |
| AU2017299983B2 (en) * | 2016-07-21 | 2021-01-07 | Kolon Life Science, Inc. | Recombinant vaccinia virus and use thereof |
| WO2018209315A1 (en) | 2017-05-12 | 2018-11-15 | Memorial Sloan Kettering Cancer Center | Vaccinia virus mutants useful for cancer immunotherapy |
| CN109554353B (zh) * | 2017-09-26 | 2021-08-06 | 杭州康万达医药科技有限公司 | 分离的重组溶瘤痘病毒、药物组合物及其在治疗肿瘤和/或癌症的药物中的用途 |
| KR20190059421A (ko) * | 2017-11-23 | 2019-05-31 | 주식회사 바이오녹스 | 항암바이러스의 간동맥 투여를 이용한 간암 치료방법 |
| KR20210031485A (ko) | 2018-07-13 | 2021-03-19 | 아리조나 보드 오브 리젠츠 온 비하프 오브 아리조나 스테이트 유니버시티 | Tnf를 발현하는 점액종 바이러스로 암을 치료하는 방법 |
| MX2021003013A (es) | 2018-09-15 | 2021-08-11 | Memorial Sloan Kettering Cancer Center | Poxvirus recombinantes para inmunoterapia contra cáncer. |
| US20240024393A1 (en) * | 2019-01-25 | 2024-01-25 | Virocure, Inc. | Pharmaceutical composition for preventing or treating cancer, comprising squirrel fibroma virus and reovirus |
| WO2020165730A1 (en) * | 2019-02-14 | 2020-08-20 | Ignite Immunotherapy, Inc. | Recombinant vaccinia virus and methods of use thereof |
| TW202122411A (zh) | 2019-09-02 | 2021-06-16 | 美國亞利桑那州立大學亞利桑那州評議委員會 | 以黏液瘤(myxoma)病毒治療癌症之新穎溶瘤病毒平臺 |
| DE102020101197A1 (de) * | 2020-01-20 | 2021-07-22 | Charité - Universitätsmedizin Berlin | Medizinprodukt zur Arzneimittelabgabe mit verstärkter Wirkung |
| CN116322740A (zh) | 2020-07-13 | 2023-06-23 | 特兰斯吉恩股份有限公司 | 免疫抑制的治疗 |
| WO2023213764A1 (en) | 2022-05-02 | 2023-11-09 | Transgene | Fusion polypeptide comprising an anti-pd-l1 sdab and a member of the tnfsf |
| WO2023213763A1 (en) | 2022-05-02 | 2023-11-09 | Transgene | Poxvirus encoding a binding agent comprising an anti- pd-l1 sdab |
| CN116942888B (zh) * | 2023-09-11 | 2026-03-24 | 科睿驰（深圳）医疗科技发展有限公司 | 淀粉水凝胶栓塞微球及其制备方法 |
| WO2026041811A1 (en) | 2024-08-23 | 2026-02-26 | Transgene | Recombinant poxvirus and method for regulating the expression of toxic conditional gene products of said recombinant poxvirus in a producing cell |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5073627A (en) | 1989-08-22 | 1991-12-17 | Immunex Corporation | Fusion proteins comprising GM-CSF and IL-3 |
| EP0635056A1 (en) | 1992-04-08 | 1995-01-25 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Wild-type measles virus glycoproteins: vaccine and detection method therefor |
| FR2736358B1 (fr) | 1995-07-05 | 1997-09-26 | Agronomique Inst Nat Rech | Virus myxomateux recombinant |
| WO1999012577A1 (en) | 1997-09-05 | 1999-03-18 | Nycomed Imaging As | Polymer particles made of polyvinyl alcohol and comprising a contrast agent for chemoembolization |
| FR2784580B1 (fr) * | 1998-10-16 | 2004-06-25 | Biosepra Inc | Microspheres de polyvinyl-alcool et procedes de fabrication de celles-ci |
| DE01918975T1 (de) * | 2000-03-24 | 2006-04-13 | Biosphere Medical, Inc., Rockland | Mikrokügelchen zur aktiven Embolisierung |
| AU9445801A (en) * | 2000-10-06 | 2002-04-15 | Bioglan Ab | Biodegradable microparticles for controlled release administration, with purified amylopectin-based starch of reduced molecular weight |
| JP5241059B2 (ja) * | 2002-05-09 | 2013-07-17 | オンコリティクス バイオテク，インコーポレーテッド | 腫瘍崩壊ウイルスを使用して疼痛を軽減するための方法 |
| KR20120002613A (ko) | 2002-08-12 | 2012-01-06 | 제네렉스, 인코포레이티드 | 폭스바이러스 및 암과 관련된 방법 및 조성물 |
| US8980246B2 (en) * | 2005-09-07 | 2015-03-17 | Sillajen Biotherapeutics, Inc. | Oncolytic vaccinia virus cancer therapy |
| KR101772375B1 (ko) * | 2005-09-07 | 2017-08-29 | 신라젠(주) | Ｇｍ-ｃｓｆ를 발현하는 폭스바이러스를 사용한 전이성 및/또는 전신 파종성 암의 전신 치료법 |
| US20100136092A1 (en) * | 2007-03-01 | 2010-06-03 | Shinsaku Nakagawa | Transdermal immune preparation, method for production of the same, and transdermal immunization method using the same |
| KR20080084528A (ko) * | 2007-03-15 | 2008-09-19 | 제네렉스 바이오테라퓨틱스 인크. | 종양살상형 백시니아 바이러스 암 치료 |
| ES2848650T3 (es) * | 2009-09-14 | 2021-08-11 | Sillajen Biotherapeutics Inc | Terapia combinada contra el cáncer con virus vaccinia oncolítico |
| WO2011135734A1 (ja) * | 2010-04-28 | 2011-11-03 | 株式会社アルファ・ナノ・メディカ | ウイルスの複合体、それを含有する治療薬及び治療方法 |
| JP6038801B2 (ja) * | 2010-11-29 | 2016-12-07 | セントレ ホスピタリエ ユニヴェルシテール ヴォードワ | 抗血管新生薬を含む化学塞栓療法組成物 |
| AU2012204467B2 (en) * | 2011-01-04 | 2016-08-18 | Sillajen, Inc. | Generation of antibodies to tumor antigens and generation of tumor specific complement dependent cytotoxicity by administration of oncolytic vaccinia virus |
| EP2739293B1 (en) * | 2011-08-05 | 2020-06-10 | SillaJen Biotherapeutics, Inc. | Methods and compositions for production of vaccina virus |
| WO2014031693A1 (en) * | 2012-08-20 | 2014-02-27 | Genelux Corporation | Compositions containing protein polymers and vaccinia virus, and methods of use thereof |
| US20140194370A1 (en) * | 2013-01-08 | 2014-07-10 | University Of Utah Research Foundation | Silk-elastin like protein polymers for embolization and chemoembolization to treat cancer |
| JP6827467B2 (ja) | 2015-06-19 | 2021-02-10 | シルラジェン，インコーポレイテッド | ウイルス塞栓術のための組成物および方法 |
| WO2017043815A1 (en) * | 2015-09-08 | 2017-03-16 | Sillajen, Inc. | Modified oncolytic vaccinia viruses expressing a cytokine and a car- boxylesterase and methods of use thereof |
-
2016
- 2016-06-17 JP JP2018517499A patent/JP6827467B2/ja active Active
- 2016-06-17 CN CN201680048316.5A patent/CN108025056B/zh active Active
- 2016-06-17 US US15/738,034 patent/US10517910B2/en active Active
- 2016-06-17 EP EP16840890.4A patent/EP3310383B1/en active Active
- 2016-06-17 AU AU2016313969A patent/AU2016313969B2/en not_active Ceased
- 2016-06-17 WO PCT/IB2016/000993 patent/WO2017037523A1/en not_active Ceased
- 2016-06-17 KR KR1020187001688A patent/KR102735275B1/ko active Active
- 2016-06-17 ES ES16840890T patent/ES2795010T3/es active Active
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