JP2018517455A5 - - Google Patents
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- Publication number
- JP2018517455A5 JP2018517455A5 JP2017556546A JP2017556546A JP2018517455A5 JP 2018517455 A5 JP2018517455 A5 JP 2018517455A5 JP 2017556546 A JP2017556546 A JP 2017556546A JP 2017556546 A JP2017556546 A JP 2017556546A JP 2018517455 A5 JP2018517455 A5 JP 2018517455A5
- Authority
- JP
- Japan
- Prior art keywords
- product stream
- inactivated
- solution
- separating agent
- virus inactivation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000700605 Viruses Species 0.000 claims 3
- 230000002779 inactivation Effects 0.000 claims 3
- FGUUSXIOTUKUDN-IBGZPJMESA-N C1(=CC=CC=C1)N1C2=C(NC([C@H](C1)NC=1OC(=NN=1)C1=CC=CC=C1)=O)C=CC=C2 Chemical compound C1(=CC=CC=C1)N1C2=C(NC([C@H](C1)NC=1OC(=NN=1)C1=CC=CC=C1)=O)C=CC=C2 FGUUSXIOTUKUDN-IBGZPJMESA-N 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15165505.7A EP3088006A1 (de) | 2015-04-28 | 2015-04-28 | Verfahren zur kontinuierlichen virusinaktivierung in einem mikroreaktor |
| EP15165505.7 | 2015-04-28 | ||
| PCT/EP2016/059169 WO2016173982A1 (de) | 2015-04-28 | 2016-04-25 | Verfahren zur kontinuierlichen virusinaktivierung in einem mikroreaktor |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018517455A JP2018517455A (ja) | 2018-07-05 |
| JP2018517455A5 true JP2018517455A5 (enExample) | 2019-02-28 |
| JP6851981B2 JP6851981B2 (ja) | 2021-03-31 |
Family
ID=53016520
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017556546A Expired - Fee Related JP6851981B2 (ja) | 2015-04-28 | 2016-04-25 | マイクロリアクター中での連続的なウイルス不活化方法 |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US10434201B2 (enExample) |
| EP (2) | EP3088006A1 (enExample) |
| JP (1) | JP6851981B2 (enExample) |
| KR (1) | KR20170140219A (enExample) |
| CN (1) | CN107624073B (enExample) |
| AR (1) | AR104440A1 (enExample) |
| AU (1) | AU2016254582C1 (enExample) |
| BR (1) | BR112017023246B1 (enExample) |
| CA (1) | CA2983884A1 (enExample) |
| DK (1) | DK3288596T3 (enExample) |
| ES (1) | ES2720034T3 (enExample) |
| IL (1) | IL255137B (enExample) |
| MX (1) | MX380149B (enExample) |
| RU (1) | RU2719363C2 (enExample) |
| SA (1) | SA517390240B1 (enExample) |
| SG (1) | SG11201708749WA (enExample) |
| TR (1) | TR201904906T4 (enExample) |
| TW (1) | TWI695070B (enExample) |
| WO (1) | WO2016173982A1 (enExample) |
| ZA (1) | ZA201708043B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11732003B2 (en) | 2017-05-11 | 2023-08-22 | Emd Millipore Corporation | Mechanical method of maintaining narrow residence time distributions in continuous flow systems |
| WO2018208448A1 (en) * | 2017-05-11 | 2018-11-15 | Emd Millipore Corporation | Method of maintaining narrow residence time distributions in continuous flow systems |
| CN111050809B (zh) | 2017-07-10 | 2021-12-24 | 武田药品工业株式会社 | 孵育液体和灭活病毒的方法 |
| WO2020076681A1 (en) * | 2018-10-08 | 2020-04-16 | Boehringer Ingelheim International Gmbh | A novel continuous flow reactor for low ph viral inactivation |
| DE102018009597A1 (de) | 2018-12-07 | 2020-06-10 | Sartorius Stedim Biotech Gmbh | Vorrichtung und Verfahren zur mehrfachen Änderung der Zusammensetzung eines Fluids |
| CN114247395B (zh) * | 2020-09-23 | 2023-04-25 | 中国科学院大连化学物理研究所 | 一种中空纤维膜式微通道反应器及应用 |
| GB2631765A (en) | 2023-07-13 | 2025-01-15 | Univ Cranfield | Viral inactivation reactor and method |
| CN117298304B (zh) * | 2023-09-18 | 2025-08-22 | 浙江大学 | 一种组装式连续病毒灭活装置及其设计方法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE194921T1 (de) * | 1992-03-02 | 2000-08-15 | Bioeng Inc | Verfahren zur inaktivierung von viren |
| EP0912238B1 (en) | 1996-07-15 | 2001-10-10 | CalCiTech Ltd. | Production of powders |
| GB2359765B (en) * | 2000-03-02 | 2003-03-05 | Univ Newcastle | Capillary reactor distribution device and method |
| DE10056096A1 (de) | 2000-11-13 | 2002-06-13 | Bayer Ag | Vorrichtung zur Bestrahlung von Flüssigkeiten |
| AU2954502A (en) | 2000-11-13 | 2002-05-21 | Bayer Ag | Method of inactivating microorganisms in a fluid using ultraviolet radiation |
| DE10312765A1 (de) | 2003-03-21 | 2004-09-30 | Bayer Technology Services Gmbh | Vorrichtung und Verfahren zur Sterilisation flüssiger Medien mittels UV-Bestrahlung und Kurzzeiterhitzung |
| US7485671B2 (en) * | 2003-05-16 | 2009-02-03 | Velocys, Inc. | Process for forming an emulsion using microchannel process technology |
| JP4611989B2 (ja) * | 2003-05-16 | 2011-01-12 | ヴェロシス，インク． | マイクロチャネルプロセス技術を用いてエマルジョンを作製するプロセス |
| US7993580B2 (en) * | 2004-08-24 | 2011-08-09 | Baxter International Inc. | Methods for the inactivation of microorganisms in biological fluids, flow through reactors and methods of controlling the light sum dose to effectively inactivate microorganisms in batch reactors |
| WO2006027757A2 (en) * | 2004-09-09 | 2006-03-16 | Institut Curie | Microfluidic device using a collinear electric field |
| JP5643474B2 (ja) * | 2004-10-01 | 2014-12-17 | ヴェロシス，インク． | マイクロチャネルプロセス技術を用いる多相混合プロセス |
| CN1786018B (zh) * | 2005-12-12 | 2011-06-22 | 天津协和生物科技发展有限公司 | 高纯度血红蛋白的分离纯化与病毒灭活工艺 |
| DE102006019242A1 (de) | 2006-04-21 | 2007-10-25 | Bayer Technology Services Gmbh | Prozessanalysensystem mit steriler Probenahme von mechanisch empfindlichem Material aus einem Bioreaktor |
| KR20100057597A (ko) * | 2007-08-10 | 2010-05-31 | 가부시키가이샤 니혼포토사이언스 | 단파장 자외선 방전등과 자외선 조사 처리 장치 |
| US8187554B2 (en) * | 2008-04-23 | 2012-05-29 | Microfluidics International Corporation | Apparatus and methods for nanoparticle generation and process intensification of transport and reaction systems |
| TW201028433A (en) * | 2008-10-20 | 2010-08-01 | Abbott Lab | Viral inactivation during purification of antibodies |
| US8956566B2 (en) * | 2012-03-12 | 2015-02-17 | Pure Biosolutions, Llc | System and method for virus inactivation |
| EP2918294A1 (de) * | 2014-03-11 | 2015-09-16 | Bayer Technology Services GmbH | Vorrichtung und Verfahren zur kontinuierlichen Virusinaktivierung |
-
2015
- 2015-04-28 EP EP15165505.7A patent/EP3088006A1/de not_active Withdrawn
-
2016
- 2016-04-25 ES ES16718357T patent/ES2720034T3/es active Active
- 2016-04-25 DK DK16718357.3T patent/DK3288596T3/da active
- 2016-04-25 MX MX2017013893A patent/MX380149B/es unknown
- 2016-04-25 RU RU2017141168A patent/RU2719363C2/ru active
- 2016-04-25 SG SG11201708749WA patent/SG11201708749WA/en unknown
- 2016-04-25 JP JP2017556546A patent/JP6851981B2/ja not_active Expired - Fee Related
- 2016-04-25 TR TR2019/04906T patent/TR201904906T4/tr unknown
- 2016-04-25 EP EP16718357.3A patent/EP3288596B1/de active Active
- 2016-04-25 AU AU2016254582A patent/AU2016254582C1/en not_active Ceased
- 2016-04-25 CN CN201680024485.5A patent/CN107624073B/zh not_active Expired - Fee Related
- 2016-04-25 BR BR112017023246-4A patent/BR112017023246B1/pt not_active IP Right Cessation
- 2016-04-25 WO PCT/EP2016/059169 patent/WO2016173982A1/de not_active Ceased
- 2016-04-25 CA CA2983884A patent/CA2983884A1/en not_active Abandoned
- 2016-04-25 KR KR1020177030712A patent/KR20170140219A/ko not_active Ceased
- 2016-04-25 US US15/569,635 patent/US10434201B2/en not_active Expired - Fee Related
- 2016-04-26 TW TW105112897A patent/TWI695070B/zh not_active IP Right Cessation
- 2016-04-28 AR ARP160101209A patent/AR104440A1/es active IP Right Grant
-
2017
- 2017-10-19 IL IL255137A patent/IL255137B/en active IP Right Grant
- 2017-10-26 SA SA517390240A patent/SA517390240B1/ar unknown
- 2017-11-27 ZA ZA2017/08043A patent/ZA201708043B/en unknown
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