|
US6777217B1
(en)
|
1996-03-26 |
2004-08-17 |
President And Fellows Of Harvard College |
Histone deacetylases, and uses related thereto
|
|
US20030129724A1
(en)
|
2000-03-03 |
2003-07-10 |
Grozinger Christina M. |
Class II human histone deacetylases, and uses related thereto
|
|
JP2003528074A
(ja)
|
2000-03-24 |
2003-09-24 |
メチルジーン インコーポレイテッド |
ヒストン脱アセチル化酵素の阻害剤
|
|
WO2002074298A1
(en)
|
2001-03-21 |
2002-09-26 |
Ono Pharmaceutical Co., Ltd. |
Il-6 production inhibitors
|
|
US7244853B2
(en)
|
2001-05-09 |
2007-07-17 |
President And Fellows Of Harvard College |
Dioxanes and uses thereof
|
|
AU2002363174B2
(en)
|
2001-11-01 |
2008-09-25 |
Janssen Pharmaceutica N.V. |
Amide derivatives as glycogen synthase kinase 3-beta inhibitors
|
|
US7154002B1
(en)
|
2002-10-08 |
2006-12-26 |
Takeda San Diego, Inc. |
Histone deacetylase inhibitors
|
|
US7375228B2
(en)
|
2003-03-17 |
2008-05-20 |
Takeda San Diego, Inc. |
Histone deacetylase inhibitors
|
|
CA2561617A1
(en)
|
2004-04-05 |
2005-10-20 |
Aton Pharma, Inc. |
Histone deacetylase inhibitor prodrugs
|
|
SG171690A1
(en)
|
2005-03-22 |
2011-06-29 |
Harvard College |
Treatment of protein degradation disorders
|
|
CA2620414A1
(en)
|
2005-08-26 |
2007-03-01 |
Methylgene Inc. |
Benzodiazepine and benzopiperazine analog inhibitors of histone deacetylase
|
|
WO2008091349A1
(en)
|
2006-02-14 |
2008-07-31 |
The President And Fellows Of Harvard College |
Bifunctional histone deacetylase inhibitors
|
|
WO2007130429A2
(en)
|
2006-05-03 |
2007-11-15 |
The President And Fellows Of Harvard College |
Histone deacetylase and tubulin deacetylase inhibitors
|
|
WO2007144341A1
(en)
|
2006-06-12 |
2007-12-21 |
Vrije Universiteit Brussel |
Differentiation of rat liver epithelial cells into hepatocyte-like cells
|
|
ES2288802B1
(es)
|
2006-07-07 |
2008-12-16 |
Universidad De Granada |
Nuevos derivados de ftalimida como inhibidores de las histonas desacetilasas.
|
|
WO2008033746A2
(en)
|
2006-09-11 |
2008-03-20 |
Curis, Inc. |
Tyrosine kinase inhibitors containing a zinc binding moiety
|
|
TWI478709B
(zh)
|
2008-02-19 |
2015-04-01 |
Earnest Medicine Co Ltd |
A useful oral or enteral composition for the recovery of bodily functions
|
|
EP2321264B1
(en)
|
2008-07-23 |
2016-05-04 |
President and Fellows of Harvard College |
Deacetylase inhibitors and uses thereof
|
|
US8716326B2
(en)
|
2009-05-15 |
2014-05-06 |
Korea Research Institute Of Chemical Technology |
Isoindolinone derivatives, preparation method thereof and a pharmaceutical composition comprising same
|
|
US8716344B2
(en)
|
2009-08-11 |
2014-05-06 |
President And Fellows Of Harvard College |
Class- and isoform-specific HDAC inhibitors and uses thereof
|
|
WO2011084991A2
(en)
|
2010-01-08 |
2011-07-14 |
President And Fellows Of Harvard College |
Fluorinated hdac inhibitors and uses thereof
|
|
PL2526093T3
(pl)
|
2010-01-22 |
2017-02-28 |
Acetylon Pharmaceuticals, Inc. |
Odwrócone związki amidowe jako inhibitory deacetylazy białkowej oraz sposoby ich stosowania
|
|
EP2571352A4
(en)
|
2010-05-21 |
2014-09-17 |
Sloan Kettering Inst Cancer |
SELECTIVE HDAC HEMMER
|
|
WO2012018499A2
(en)
|
2010-08-05 |
2012-02-09 |
Acetylon Pharmaceuticals |
Specific regulation of cytokine levels by hdac6 inhibitors
|
|
NZ610225A
(en)
|
2010-11-16 |
2015-08-28 |
Acetylon Pharmaceuticals Inc |
Pyrimidine hydroxy amide compounds as protein deacetylase inhibitors and methods of use thereof
|
|
EP2734500A4
(en)
|
2011-07-20 |
2015-04-08 |
Gen Hospital Corp |
SELECTIVE HISTONDEACETYLASE-6 INHIBITORS FOR THE TREATMENT OF BONE DISORDERS
|
|
HK1207403A1
(en)
|
2012-04-19 |
2016-01-29 |
Acetylon Pharmaceuticals, Inc. |
Biomarkers to identify patients that will respond to treatment and treating such patients
|
|
WO2014059306A1
(en)
|
2012-10-12 |
2014-04-17 |
The Trustees Of The University Of Pennsylvania |
Pyrimidine hydroxy amide compounds as protein deacetylase inhibitors and methods of use thereof
|
|
US9145412B2
(en)
|
2012-11-02 |
2015-09-29 |
Acetylon Pharmaceuticals, Inc. |
Selective HDAC1 and HDAC2 inhibitors
|
|
JP2016511237A
(ja)
|
2013-02-01 |
2016-04-14 |
アセチロン ファーマシューティカルズ インコーポレイテッドAcetylon Pharmaceuticals,Inc. |
選択的hdac3阻害剤
|
|
US9139583B2
(en)
|
2013-02-01 |
2015-09-22 |
Acetylon Pharmaceuticals, Inc. |
Selective HDAC3 inhibitors
|
|
US20140357512A1
(en)
|
2013-06-03 |
2014-12-04 |
Acetylon Pharmaceuticals, Inc. |
Histone deacetylase (hdac) biomarkers in multiple myeloma
|
|
JP2016531163A
(ja)
|
2013-09-20 |
2016-10-06 |
アセチロン ファーマシューティカルズ インコーポレイテッドAcetylon Pharmaceuticals,Inc. |
Hdac6阻害物質を用いた、異常なリンパ球の機能に起因する疾患の治療
|
|
WO2015054099A1
(en)
|
2013-10-08 |
2015-04-16 |
Acetylon Pharmaceuticals, Inc. |
Combinations of histone deacetylase inhibitors and either her2 inhibitors or pi3k inhibitors
|
|
WO2015054197A1
(en)
|
2013-10-10 |
2015-04-16 |
Acetylon Pharmaceuticals, Inc. |
Hdac inhibitors, alone or in combination with btk inhibitors, for treating non-hodgkin's lymphoma
|
|
EP3055299B1
(en)
|
2013-10-10 |
2021-01-06 |
Acetylon Pharmaceuticals, Inc. |
Pyrimidine hydroxy amide compounds as histone deacetylase inhibitors
|
|
ES2818933T3
(es)
|
2013-10-10 |
2021-04-14 |
Acetylon Pharmaceuticals Inc |
Inhibidores de la HDAC en combinación con los inhibidores de la pi3k, para el tratamiento del linfoma no Hodgkin
|
|
PE20161342A1
(es)
|
2013-10-11 |
2016-12-31 |
Acetylon Pharmaceuticals Inc |
Combinaciones de inhibidores de histona desacetilasa y farmacos inmunomoduladores
|
|
EP3060217B1
(en)
|
2013-10-24 |
2022-06-08 |
Mayo Foundation for Medical Education and Research |
Treatment of polycystic diseases with an hdac6 inhibitor
|
|
EP3076973B1
(en)
|
2013-12-03 |
2020-04-29 |
Acetylon Pharmaceuticals, Inc. |
Combinations of histone deacetylase inhibitors and immunomodulatory drugs
|
|
US20150176076A1
(en)
|
2013-12-20 |
2015-06-25 |
Acetylon Pharmaceuticals, Inc. |
Histone deacetylase 6 (hdac6) biomarkers in multiple myeloma
|
|
US9464073B2
(en)
|
2014-02-26 |
2016-10-11 |
Acetylon Pharmaceuticals, Inc. |
Pyrimidine hydroxy amide compounds as HDAC6 selective inhibitors
|
|
US20150359794A1
(en)
|
2014-06-13 |
2015-12-17 |
Buck Institute For Research On Aging |
Impairment of the large ribosomal subunit protein rpl24 by depletion or acetylation
|
|
CN107205988A
(zh)
|
2014-07-07 |
2017-09-26 |
埃斯泰隆制药公司 |
利用组蛋白脱乙酰酶抑制剂治疗白血病
|
|
US20160137630A1
(en)
|
2014-10-08 |
2016-05-19 |
Acetylon Pharmaceuticals, Inc. |
Induction of gata2 by hdac1 and hdac2 inhibitors
|
|
CN107438436A
(zh)
|
2014-12-05 |
2017-12-05 |
摩德纳和雷焦艾米利亚大学 |
用于治疗淋巴瘤的组蛋白脱乙酰酶抑制剂和苯达莫司汀的组合
|
|
US20160158231A1
(en)
|
2014-12-05 |
2016-06-09 |
Vib Vzw |
Pyrimidine hydroxy amide compounds for treating peripheral neuropathy
|
|
CA2970500C
(en)
|
2014-12-12 |
2023-08-29 |
Acetylon Pharmaceuticals, Inc. |
Piperidine derivatives as hdac1/2 inhibitors
|
|
WO2016168647A1
(en)
|
2015-04-17 |
2016-10-20 |
Acetylon Pharmaceuticals Inc. |
Treatment of neuroblastoma with histone deacetylase inhibotrs
|
|
US10272084B2
(en)
|
2015-06-01 |
2019-04-30 |
Regenacy Pharmaceuticals, Llc |
Histone deacetylase 6 selective inhibitors for the treatment of cisplatin-induced peripheral neuropathy
|
|
TWI706937B
(zh)
|
2015-06-08 |
2020-10-11 |
美商艾斯特隆製藥公司 |
製備蛋白質去乙醯酶抑制劑之方法
|