|
US6777217B1
(en)
|
1996-03-26 |
2004-08-17 |
President And Fellows Of Harvard College |
Histone deacetylases, and uses related thereto
|
|
US20030129724A1
(en)
|
2000-03-03 |
2003-07-10 |
Grozinger Christina M. |
Class II human histone deacetylases, and uses related thereto
|
|
AU2001248701A1
(en)
|
2000-03-24 |
2001-10-03 |
Methylgene, Inc. |
Inhibitors of histone deacetylase
|
|
JPWO2002074298A1
(ja)
|
2001-03-21 |
2004-07-08 |
小野薬品工業株式会社 |
Ｉｌ−６産生阻害剤
|
|
US7244853B2
(en)
|
2001-05-09 |
2007-07-17 |
President And Fellows Of Harvard College |
Dioxanes and uses thereof
|
|
CN1582277A
(zh)
|
2001-11-01 |
2005-02-16 |
詹森药业有限公司 |
用作糖原合酶激酶3β抑制剂的酰胺衍生物
|
|
US7154002B1
(en)
|
2002-10-08 |
2006-12-26 |
Takeda San Diego, Inc. |
Histone deacetylase inhibitors
|
|
KR20050122210A
(ko)
|
2003-03-17 |
2005-12-28 |
다케다 샌디에고, 인코포레이티드 |
히스톤 탈아세틸화 효소 억제제
|
|
EP1745022B1
(en)
|
2004-04-05 |
2014-08-13 |
Aton Pharma, Inc. |
Histone deacetylase inhibitor prodrugs
|
|
US8999289B2
(en)
|
2005-03-22 |
2015-04-07 |
President And Fellows Of Harvard College |
Treatment of protein degradation disorders
|
|
EP1940805A4
(en)
|
2005-08-26 |
2009-11-11 |
Methylgene Inc |
BENZODIAZEPIN AND BENZOPIPERAZINANALOGA AS INHIBITORS OF HISTONDEACETYLASE
|
|
US8222423B2
(en)
|
2006-02-14 |
2012-07-17 |
Dana-Farber Cancer Institute, Inc. |
Bifunctional histone deacetylase inhibitors
|
|
AU2007248656B2
(en)
|
2006-05-03 |
2013-04-04 |
Dana-Farber Cancer Institute, Inc. |
Histone deacetylase and tubulin deacetylase inhibitors
|
|
WO2007144341A1
(en)
|
2006-06-12 |
2007-12-21 |
Vrije Universiteit Brussel |
Differentiation of rat liver epithelial cells into hepatocyte-like cells
|
|
ES2288802B1
(es)
|
2006-07-07 |
2008-12-16 |
Universidad De Granada |
Nuevos derivados de ftalimida como inhibidores de las histonas desacetilasas.
|
|
CA2662580C
(en)
|
2006-09-11 |
2013-05-21 |
Curis, Inc. |
Tyrosine kinase inhibitors containing a zinc binding moiety
|
|
WO2009104696A1
(ja)
|
2008-02-19 |
2009-08-27 |
株式会社アーネストメディスン |
身体機能の回復に有用な経口又は経腸組成物
|
|
US8440716B2
(en)
|
2008-07-23 |
2013-05-14 |
President And Fellows Of Harvard College |
Deacetylase inhibitors and uses thereof
|
|
US8716326B2
(en)
|
2009-05-15 |
2014-05-06 |
Korea Research Institute Of Chemical Technology |
Isoindolinone derivatives, preparation method thereof and a pharmaceutical composition comprising same
|
|
US8716344B2
(en)
|
2009-08-11 |
2014-05-06 |
President And Fellows Of Harvard College |
Class- and isoform-specific HDAC inhibitors and uses thereof
|
|
US20130040998A1
(en)
|
2010-01-08 |
2013-02-14 |
Dana-Farber Cancer Institute, Inc. |
Fluorinated hdac inhibitors and uses thereof
|
|
NZ601655A
(en)
|
2010-01-22 |
2014-10-31 |
Acetylon Pharmaceuticals Inc |
Reverse amide compounds as protein deacetylase inhibitors and methods of use thereof
|
|
EP2571352A4
(en)
|
2010-05-21 |
2014-09-17 |
Sloan Kettering Inst Cancer |
SELECTIVE HDAC HEMMER
|
|
WO2012018499A2
(en)
|
2010-08-05 |
2012-02-09 |
Acetylon Pharmaceuticals |
Specific regulation of cytokine levels by hdac6 inhibitors
|
|
PL2640709T3
(pl)
|
2010-11-16 |
2016-10-31 |
|
Związki pirymidynohydroksyamidowe jako inhibitory deacetylazy białkowej oraz sposoby ich stosowania”
|
|
JP6169076B2
(ja)
|
2011-07-20 |
2017-07-26 |
ザ ジェネラル ホスピタル コーポレイション |
骨疾患の処置のためのヒストン脱アセチル化酵素６選択的阻害剤
|
|
EP2839037B1
(en)
|
2012-04-19 |
2018-12-26 |
Acetylon Pharmaceuticals, Inc. |
Biomarkers to identify patients that will respond to treatment and treating such patients
|
|
US20150250786A1
(en)
|
2012-10-12 |
2015-09-10 |
The Trustees Of The University Of Pennsylvania |
Pyrimidine hydroxy amide compounds as protein deacetylase inhibitors and methods of use thereof
|
|
US9145412B2
(en)
|
2012-11-02 |
2015-09-29 |
Acetylon Pharmaceuticals, Inc. |
Selective HDAC1 and HDAC2 inhibitors
|
|
WO2014121062A1
(en)
|
2013-02-01 |
2014-08-07 |
Acetylon Pharmaceuticals, Inc. |
Selective hdac3 inhibitors
|
|
US9139583B2
(en)
|
2013-02-01 |
2015-09-22 |
Acetylon Pharmaceuticals, Inc. |
Selective HDAC3 inhibitors
|
|
EP3004141A4
(en)
|
2013-06-03 |
2017-05-31 |
Acetylon Pharmaceuticals, Inc. |
Histone deacetylase ( hdac) biomarkers in multiple myeloma
|
|
WO2015042418A1
(en)
|
2013-09-20 |
2015-03-26 |
Acetylon Pharmaceuticals, Inc. |
Treatment of diseases caused by abnormal lymphocyte function with an hdac6 inhibitor
|
|
WO2015054099A1
(en)
|
2013-10-08 |
2015-04-16 |
Acetylon Pharmaceuticals, Inc. |
Combinations of histone deacetylase inhibitors and either her2 inhibitors or pi3k inhibitors
|
|
JP2016536354A
(ja)
|
2013-10-10 |
2016-11-24 |
アセチロン ファーマシューティカルズ インコーポレイテッドＡｃｅｔｙｌｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． |
非ホジキンリンパ腫を治療するための、ｈｄａｃ阻害剤単独またはｂｔｋ阻害剤との組み合わせ
|
|
ES2862126T3
(es)
|
2013-10-10 |
2021-10-07 |
Acetylon Pharmaceuticals Inc |
Compuestos de pirimidín-hidroxiamida como inhibidores de histona desacetilasa
|
|
US20150105383A1
(en)
|
2013-10-10 |
2015-04-16 |
Acetylon Pharmaceuticals, Inc. |
HDAC Inhibitors, Alone Or In Combination With PI3K Inhibitors, For Treating Non-Hodgkin's Lymphoma
|
|
KR20160060143A
(ko)
|
2013-10-11 |
2016-05-27 |
에이스틸론 파마수티컬스 인코포레이티드 |
히스톤 디아세틸라아제 억제제와 면역조절성 약물의 조합물
|
|
US10660890B2
(en)
|
2013-10-24 |
2020-05-26 |
National Institutes Of Health (Nih), U.S. Dept. Of Health And Human Services (Dhhs), U.S. Government Nih Division Of Extramural Inventions And Technology Resources (Deitr) |
Treatment of polycystic diseases with an HDAC6 inhibitor
|
|
ES2806258T3
(es)
|
2013-12-03 |
2021-02-17 |
Acetylon Pharmaceuticals Inc |
Combinaciones de inhibidores de histona desacetilasa y fármacos inmunomoduladores
|
|
WO2015095632A1
(en)
|
2013-12-20 |
2015-06-25 |
Acetylon Pharmaceuticals, Inc. |
Histone deacetylase 6 (hdac6) biomarkers in multiple myeloma
|
|
US9464073B2
(en)
|
2014-02-26 |
2016-10-11 |
Acetylon Pharmaceuticals, Inc. |
Pyrimidine hydroxy amide compounds as HDAC6 selective inhibitors
|
|
US20150359794A1
(en)
|
2014-06-13 |
2015-12-17 |
Buck Institute For Research On Aging |
Impairment of the large ribosomal subunit protein rpl24 by depletion or acetylation
|
|
SG11201700094TA
(en)
|
2014-07-07 |
2017-02-27 |
Acetylon Pharmaceuticals Inc |
Treatment of leukemia with histone deacetylase inhibitors
|
|
US20160137630A1
(en)
|
2014-10-08 |
2016-05-19 |
Acetylon Pharmaceuticals, Inc. |
Induction of gata2 by hdac1 and hdac2 inhibitors
|
|
WO2016090230A1
(en)
|
2014-12-05 |
2016-06-09 |
Acetylon Pharmaceuticals, Inc. |
Pyrimidine hydroxy amide compounds for treating peripheral neuropathy
|
|
US9937174B2
(en)
|
2014-12-05 |
2018-04-10 |
University of Modena and Reggio Emilia |
Combinations of histone deacetylase inhibitors and bendamustine
|
|
BR112017012504A2
(pt)
|
2014-12-12 |
2018-01-09 |
Acetylon Pharmaceuticals, Inc. |
derivados de piperidina como inibidores de hdac1/2
|
|
WO2016168647A1
(en)
|
2015-04-17 |
2016-10-20 |
Acetylon Pharmaceuticals Inc. |
Treatment of neuroblastoma with histone deacetylase inhibotrs
|
|
US10272084B2
(en)
|
2015-06-01 |
2019-04-30 |
Regenacy Pharmaceuticals, Llc |
Histone deacetylase 6 selective inhibitors for the treatment of cisplatin-induced peripheral neuropathy
|
|
CN107922352B
(zh)
|
2015-06-08 |
2021-08-06 |
埃斯泰隆制药公司 |
制备蛋白质脱乙酰酶抑制剂的方法
|