|
US6777217B1
(en)
|
1996-03-26 |
2004-08-17 |
President And Fellows Of Harvard College |
Histone deacetylases, and uses related thereto
|
|
US20030129724A1
(en)
|
2000-03-03 |
2003-07-10 |
Grozinger Christina M. |
Class II human histone deacetylases, and uses related thereto
|
|
ATE489360T1
(de)
|
2000-03-24 |
2010-12-15 |
Methylgene Inc |
Inhibitoren der histon-deacetylase
|
|
US20050119305A1
(en)
|
2001-03-21 |
2005-06-02 |
Masao Naka |
Il-6 production inhibitors
|
|
US7244853B2
(en)
|
2001-05-09 |
2007-07-17 |
President And Fellows Of Harvard College |
Dioxanes and uses thereof
|
|
MXPA04004177A
(es)
|
2001-11-01 |
2004-09-06 |
Janssen Pharmaceutica Nv |
Derivados de amida como inhibidores de la glicogeno cintasa cinasa 3-beta.
|
|
US7154002B1
(en)
|
2002-10-08 |
2006-12-26 |
Takeda San Diego, Inc. |
Histone deacetylase inhibitors
|
|
CA2518318A1
(en)
|
2003-03-17 |
2004-09-30 |
Takeda San Diego, Inc. |
Histone deacetylase inhibitors
|
|
AU2005230682B2
(en)
|
2004-04-05 |
2010-10-21 |
Merck Hdac Research, Llc |
Histone deacetylase inhibitor prodrugs
|
|
EP2491926B1
(en)
|
2005-03-22 |
2018-05-09 |
President and Fellows of Harvard College |
Treatment of protein degradation disorders
|
|
CA2620414A1
(en)
|
2005-08-26 |
2007-03-01 |
Methylgene Inc. |
Benzodiazepine and benzopiperazine analog inhibitors of histone deacetylase
|
|
AU2007345292B2
(en)
|
2006-02-14 |
2013-10-31 |
Dana-Farber Cancer Institute, Inc. |
Bifunctional histone deacetylase inhibitors
|
|
JP5497431B2
(ja)
|
2006-05-03 |
2014-05-21 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
ヒストンデアセチラーゼおよびチューブリンデアセチラーゼ阻害剤
|
|
US20100278782A1
(en)
|
2006-06-12 |
2010-11-04 |
Vrije Universiteit Brussel |
Differentiation of rat liver epithelial cells into hepatocyte-like cells
|
|
ES2288802B1
(es)
|
2006-07-07 |
2008-12-16 |
Universidad De Granada |
Nuevos derivados de ftalimida como inhibidores de las histonas desacetilasas.
|
|
CN101534831B
(zh)
|
2006-09-11 |
2013-07-17 |
柯瑞斯公司 |
包含锌结合基团的取代的酪氨酸抑制剂
|
|
EP2255818B1
(en)
|
2008-02-19 |
2018-08-22 |
Earnest Medicine Co., Ltd. |
Oral or enteral composition useful for recovery of physical functions
|
|
US8440716B2
(en)
|
2008-07-23 |
2013-05-14 |
President And Fellows Of Harvard College |
Deacetylase inhibitors and uses thereof
|
|
US8716326B2
(en)
|
2009-05-15 |
2014-05-06 |
Korea Research Institute Of Chemical Technology |
Isoindolinone derivatives, preparation method thereof and a pharmaceutical composition comprising same
|
|
US8716344B2
(en)
|
2009-08-11 |
2014-05-06 |
President And Fellows Of Harvard College |
Class- and isoform-specific HDAC inhibitors and uses thereof
|
|
EP2638009A4
(en)
|
2010-01-08 |
2014-06-11 |
Harvard College |
FLUORINATED HDAC HEMMER AND USES THEREOF
|
|
EP2526093B1
(en)
|
2010-01-22 |
2016-08-17 |
Acetylon Pharmaceuticals, Inc. |
Reverse amide compounds as protein deacetylase inhibitors and methods of use thereof
|
|
CA2800143A1
(en)
|
2010-05-21 |
2011-11-24 |
The Trustees Of Columbia University In The City Of New York |
Selective hdac inhibitors
|
|
WO2012018499A2
(en)
|
2010-08-05 |
2012-02-09 |
Acetylon Pharmaceuticals |
Specific regulation of cytokine levels by hdac6 inhibitors
|
|
PL2640709T3
(pl)
|
2010-11-16 |
2016-10-31 |
|
Związki pirymidynohydroksyamidowe jako inhibitory deacetylazy białkowej oraz sposoby ich stosowania”
|
|
JP6169076B2
(ja)
|
2011-07-20 |
2017-07-26 |
ザ ジェネラル ホスピタル コーポレイション |
骨疾患の処置のためのヒストン脱アセチル化酵素６選択的阻害剤
|
|
US9663825B2
(en)
|
2012-04-19 |
2017-05-30 |
Acetylon Pharmaceuticals, Inc. |
Biomarkers to identify patients that will respond to treatment and treating such patients
|
|
HK1213471A1
(zh)
|
2012-10-12 |
2016-07-08 |
The Trustees Of The University Of Pennsylvania |
作為蛋白脫乙酰基酶抑制劑的嘧啶羥基酰胺化合物及其使用方法
|
|
US9145412B2
(en)
|
2012-11-02 |
2015-09-29 |
Acetylon Pharmaceuticals, Inc. |
Selective HDAC1 and HDAC2 inhibitors
|
|
US9139583B2
(en)
|
2013-02-01 |
2015-09-22 |
Acetylon Pharmaceuticals, Inc. |
Selective HDAC3 inhibitors
|
|
EP2951153B1
(en)
|
2013-02-01 |
2019-04-03 |
Regenacy Pharmaceuticals, LLC |
Selective hdac3 inhibitors
|
|
EP3004141A4
(en)
|
2013-06-03 |
2017-05-31 |
Acetylon Pharmaceuticals, Inc. |
Histone deacetylase ( hdac) biomarkers in multiple myeloma
|
|
JP2016531163A
(ja)
|
2013-09-20 |
2016-10-06 |
アセチロン ファーマシューティカルズ インコーポレイテッドＡｃｅｔｙｌｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． |
Ｈｄａｃ６阻害物質を用いた、異常なリンパ球の機能に起因する疾患の治療
|
|
EP3054952B1
(en)
|
2013-10-08 |
2022-10-26 |
Acetylon Pharmaceuticals, Inc. |
Combinations of histone deacetylase 6 inhibitors and the her2 inhibitor lapatinib for use in the treatment of breast cancer
|
|
US20150105383A1
(en)
|
2013-10-10 |
2015-04-16 |
Acetylon Pharmaceuticals, Inc. |
HDAC Inhibitors, Alone Or In Combination With PI3K Inhibitors, For Treating Non-Hodgkin's Lymphoma
|
|
EP3054954A4
(en)
*
|
2013-10-10 |
2017-12-13 |
Acetylon Pharmaceuticals, Inc. |
Hdac inhibitors, alone or in combination with btk inhibitors, for treating non-hodgkin's lymphoma
|
|
EP3055299B1
(en)
|
2013-10-10 |
2021-01-06 |
Acetylon Pharmaceuticals, Inc. |
Pyrimidine hydroxy amide compounds as histone deacetylase inhibitors
|
|
KR20160060143A
(ko)
|
2013-10-11 |
2016-05-27 |
에이스틸론 파마수티컬스 인코포레이티드 |
히스톤 디아세틸라아제 억제제와 면역조절성 약물의 조합물
|
|
JP2016534069A
(ja)
*
|
2013-10-24 |
2016-11-04 |
メイヨ・ファウンデーション・フォー・メディカル・エデュケーション・アンド・リサーチ |
Ｈｄａｃ６阻害剤での多嚢胞性疾患の治療
|
|
ES2806258T3
(es)
|
2013-12-03 |
2021-02-17 |
Acetylon Pharmaceuticals Inc |
Combinaciones de inhibidores de histona desacetilasa y fármacos inmunomoduladores
|
|
JP7017309B2
(ja)
|
2013-12-20 |
2022-02-08 |
アセチロン ファーマシューティカルズ インコーポレイテッド |
多発性骨髄腫におけるヒストン脱アセチル化酵素６（ｈｄａｃ６）バイオマーカー
|
|
US9464073B2
(en)
|
2014-02-26 |
2016-10-11 |
Acetylon Pharmaceuticals, Inc. |
Pyrimidine hydroxy amide compounds as HDAC6 selective inhibitors
|
|
US20150359794A1
(en)
|
2014-06-13 |
2015-12-17 |
Buck Institute For Research On Aging |
Impairment of the large ribosomal subunit protein rpl24 by depletion or acetylation
|
|
MX2017000307A
(es)
|
2014-07-07 |
2017-11-23 |
Acetylon Pharmaceuticals Inc |
Tratamiento de leucemia con inhibidores de histona deacetilasa.
|
|
CA2963681A1
(en)
|
2014-10-08 |
2016-04-14 |
Acetylon Pharmaceuticals, Inc. |
Induction of gata2 by hdac1 and hdac2 inhibitors
|
|
US20160158231A1
(en)
|
2014-12-05 |
2016-06-09 |
Vib Vzw |
Pyrimidine hydroxy amide compounds for treating peripheral neuropathy
|
|
US9937174B2
(en)
|
2014-12-05 |
2018-04-10 |
University of Modena and Reggio Emilia |
Combinations of histone deacetylase inhibitors and bendamustine
|
|
HK1251566A1
(zh)
|
2014-12-12 |
2019-02-01 |
Regenacy Pharmaceuticals, Llc |
作为hdac1/2抑制剂的呱啶衍生物
|
|
WO2016168647A1
(en)
|
2015-04-17 |
2016-10-20 |
Acetylon Pharmaceuticals Inc. |
Treatment of neuroblastoma with histone deacetylase inhibotrs
|
|
US10272084B2
(en)
|
2015-06-01 |
2019-04-30 |
Regenacy Pharmaceuticals, Llc |
Histone deacetylase 6 selective inhibitors for the treatment of cisplatin-induced peripheral neuropathy
|
|
MX369349B
(es)
|
2015-06-08 |
2019-11-06 |
Acetylon Pharmaceuticals Inc |
Metodos para hacer inhibidores de la proteina deacetilasa.
|