JP2016510768A5 - - Google Patents
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- Publication number
- JP2016510768A5 JP2016510768A5 JP2015561831A JP2015561831A JP2016510768A5 JP 2016510768 A5 JP2016510768 A5 JP 2016510768A5 JP 2015561831 A JP2015561831 A JP 2015561831A JP 2015561831 A JP2015561831 A JP 2015561831A JP 2016510768 A5 JP2016510768 A5 JP 2016510768A5
- Authority
- JP
- Japan
- Prior art keywords
- crystalline form
- form suc
- suc
- impurities
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000013078 crystal Substances 0.000 claims 4
- 239000012535 impurity Substances 0.000 claims 4
- 238000000634 powder X-ray diffraction Methods 0.000 claims 4
- 229940125904 compound 1 Drugs 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 238000001938 differential scanning calorimetry curve Methods 0.000 claims 2
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 claims 2
- 208000019901 Anxiety disease Diseases 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 230000036506 anxiety Effects 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- AICOOMRHRUFYCM-ZRRPKQBOSA-N oxazine, 1 Chemical compound C([C@@H]1[C@H](C(C[C@]2(C)[C@@H]([C@H](C)N(C)C)[C@H](O)C[C@]21C)=O)CC1=CC2)C[C@H]1[C@@]1(C)[C@H]2N=C(C(C)C)OC1 AICOOMRHRUFYCM-ZRRPKQBOSA-N 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 claims 1
- 239000001384 succinic acid Substances 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361798926P | 2013-03-15 | 2013-03-15 | |
| US61/798,926 | 2013-03-15 | ||
| PCT/AU2014/000272 WO2014138812A1 (en) | 2013-03-15 | 2014-03-14 | Salts, co-crystals, and polymorphs of an anxiolytic compound |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016510768A JP2016510768A (ja) | 2016-04-11 |
| JP2016510768A5 true JP2016510768A5 (enExample) | 2017-04-20 |
Family
ID=51535621
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015561831A Pending JP2016510768A (ja) | 2013-03-15 | 2014-03-14 | 抗不安化合物の塩、共結晶及び多形 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US9745296B2 (enExample) |
| EP (1) | EP2970247A4 (enExample) |
| JP (1) | JP2016510768A (enExample) |
| CN (1) | CN105492440A (enExample) |
| AU (2) | AU2014231722B2 (enExample) |
| CA (1) | CA2905570A1 (enExample) |
| HK (1) | HK1220191A1 (enExample) |
| MX (1) | MX2015013059A (enExample) |
| WO (1) | WO2014138812A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6688434B2 (en) | 2002-02-22 | 2004-02-10 | Ecolab Inc. | Conveyor and lubricating apparatus, lubricant dispensing device, and method for applying lubricant to conveyor |
| CN105541701A (zh) * | 2015-12-11 | 2016-05-04 | 吉林大学珠海学院 | 以顺丁烯二酸为前驱体的去铁酮药物共晶及其制备方法 |
| TWI765688B (zh) * | 2015-12-15 | 2022-05-21 | 以色列商諾發測量儀器股份有限公司 | 用於測量圖案化結構之方法及拉曼光譜系統 |
| WO2019109150A1 (en) * | 2017-12-07 | 2019-06-13 | Bionomics Limited | Methods of treating agitation |
| WO2020087031A1 (en) | 2018-10-26 | 2020-04-30 | The Research Foundation For The State University Of New York | Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia |
| CN114585362B (zh) | 2019-09-23 | 2024-05-07 | 生态有限公司 | 治疗制剂及其用途 |
| AU2023201463A1 (en) * | 2023-03-08 | 2024-09-26 | Bionomics Limited | Method of treating social anxiety disorder |
| WO2025033432A1 (ja) * | 2023-08-08 | 2025-02-13 | 株式会社明治 | 概日リズムの調整 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007502839A (ja) * | 2003-08-21 | 2007-02-15 | トランソラル ファーマシューティカルズ，インコーポレイティド | 口腔粘膜を介して５−ｈｔアゴニストを運搬するための組成物及びその使用方法 |
| JP5373613B2 (ja) | 2006-10-16 | 2013-12-18 | バイオノミクス リミテッド | 新規な抗不安薬化合物 |
| DE102006060598A1 (de) * | 2006-12-21 | 2008-06-26 | Merck Patent Gmbh | Tetrahydrobenzoisoxazole |
| GB0706044D0 (en) * | 2007-03-28 | 2007-05-09 | Syngenta Ltd | C0-Crystals |
| BR112012013365A2 (pt) * | 2009-12-03 | 2016-03-01 | Astrazeneca Ab | co-cristal do composto, método para preparar um co-cristal do composto, composição farmacêutica, uso de um co-cristal do composto, e, método de tratamento de complicações trombóticas arteriais |
| EP2680842A4 (en) * | 2011-03-02 | 2014-10-29 | Bionomics Ltd | METHOD FOR THE TREATMENT OF A DISEASE OR A SENSE OF THE CENTRAL NERVOUS SYSTEM |
| JP6055817B2 (ja) * | 2011-05-12 | 2016-12-27 | バイオノミックス リミテッド | ナフチリジンの調製方法 |
| AU2013204159B2 (en) * | 2013-03-15 | 2015-05-07 | Bionomics Limited | A Crystalline Form of an Anxiolytic Compound |
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2014
- 2014-03-14 US US14/776,643 patent/US9745296B2/en active Active
- 2014-03-14 CN CN201480028564.4A patent/CN105492440A/zh active Pending
- 2014-03-14 EP EP14765186.3A patent/EP2970247A4/en not_active Withdrawn
- 2014-03-14 CA CA2905570A patent/CA2905570A1/en not_active Abandoned
- 2014-03-14 MX MX2015013059A patent/MX2015013059A/es unknown
- 2014-03-14 HK HK16108260.8A patent/HK1220191A1/zh unknown
- 2014-03-14 WO PCT/AU2014/000272 patent/WO2014138812A1/en not_active Ceased
- 2014-03-14 AU AU2014231722A patent/AU2014231722B2/en active Active
- 2014-03-14 JP JP2015561831A patent/JP2016510768A/ja active Pending
-
2017
- 2017-03-21 AU AU2017201916A patent/AU2017201916B2/en active Active
- 2017-08-25 US US15/687,274 patent/US10266529B2/en active Active