JP2018513685A5 - - Google Patents
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- Publication number
- JP2018513685A5 JP2018513685A5 JP2017553115A JP2017553115A JP2018513685A5 JP 2018513685 A5 JP2018513685 A5 JP 2018513685A5 JP 2017553115 A JP2017553115 A JP 2017553115A JP 2017553115 A JP2017553115 A JP 2017553115A JP 2018513685 A5 JP2018513685 A5 JP 2018513685A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- complementary region
- region
- mir
- strand
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562146015P | 2015-04-10 | 2015-04-10 | |
| US62/146,015 | 2015-04-10 | ||
| PCT/US2016/026846 WO2016164866A1 (en) | 2015-04-10 | 2016-04-10 | METHOD FOR BLOCKING miRNA |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018513685A JP2018513685A (ja) | 2018-05-31 |
| JP2018513685A5 true JP2018513685A5 (enExample) | 2020-07-02 |
| JP6791875B2 JP6791875B2 (ja) | 2020-11-25 |
Family
ID=57072747
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017553115A Expired - Fee Related JP6791875B2 (ja) | 2015-04-10 | 2016-04-10 | ｍｉＲＮＡをブロックするための方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US10480023B2 (enExample) |
| EP (1) | EP3280805B1 (enExample) |
| JP (1) | JP6791875B2 (enExample) |
| AU (1) | AU2016246820B2 (enExample) |
| CA (1) | CA2982369A1 (enExample) |
| IL (1) | IL254972B (enExample) |
| MX (1) | MX386064B (enExample) |
| WO (1) | WO2016164866A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3929293A3 (en) | 2015-04-03 | 2022-03-16 | University Of Massachusetts | Fully stabilized asymmetric sirna |
| US11396650B2 (en) | 2015-06-02 | 2022-07-26 | Children's Medical Center Corporation | Nucleic acid complexes for screening barcoded compounds |
| US12077807B2 (en) | 2015-06-27 | 2024-09-03 | The Research Foundation For The State University Of New York | Compositions and methods for analyte detection using nanoswitches |
| WO2017030973A1 (en) | 2015-08-14 | 2017-02-23 | University Of Massachusetts | Bioactive conjugates for oligonucleotide delivery |
| WO2017132669A1 (en) | 2016-01-31 | 2017-08-03 | University Of Massachusetts | Branched oligonucleotides |
| US10287625B2 (en) * | 2016-03-18 | 2019-05-14 | Norgen Biotek Corp. | Methods and kits for separating nucleic acids by size |
| WO2017165647A1 (en) | 2016-03-23 | 2017-09-28 | Children's Medical Center Corporation | Rapid and sensitive detection and quantification of analytes in complex samples using polymer-based methods |
| WO2018031933A2 (en) | 2016-08-12 | 2018-02-15 | University Of Massachusetts | Conjugated oligonucleotides |
| US12252507B2 (en) | 2016-12-05 | 2025-03-18 | Children's Medical Center Corporation | Nucleic acid nanoswitch construction methods |
| AU2018224302B2 (en) * | 2017-02-27 | 2024-08-29 | Bioo Scientific Corporation | Methods and kits for depleting undesired nucleic acids |
| WO2018237245A1 (en) | 2017-06-23 | 2018-12-27 | University Of Massachusetts | TWO TAIL SELF-ADMINISTRATION SIRNA AND ASSOCIATED METHODS |
| CN111278844B (zh) * | 2017-09-13 | 2023-12-19 | 贝克顿·迪金森公司 | 用于使用氧化铁颗粒提取核酸的方法和组合物 |
| US11591636B2 (en) | 2017-11-20 | 2023-02-28 | Children's Medical Center Corporation | Force-controlled nanoswitch assays for single-molecule detection in complex biological fluids |
| CN108676846B (zh) * | 2018-05-25 | 2022-04-01 | 艾吉泰康生物科技(北京)有限公司 | 一种桥式寡核苷酸在文库目标区域捕获中的应用 |
| BR112021002440A2 (pt) | 2018-08-10 | 2021-05-04 | University Of Massachusetts | oligonucleotídeos modificados visando snps |
| WO2020041769A1 (en) | 2018-08-23 | 2020-02-27 | University Of Massachusetts | O-methyl rich fully stabilized oligonucleotides |
| CN113614232A (zh) * | 2019-01-18 | 2021-11-05 | 马萨诸塞大学 | 动态药代动力学修饰锚 |
| KR20220047989A (ko) | 2019-08-09 | 2022-04-19 | 유니버시티 오브 매사추세츠 | Snp를 표적화하는 화학적으로 변형된 올리고뉴클레오타이드 |
| US12365894B2 (en) | 2019-09-16 | 2025-07-22 | University Of Massachusetts | Branched lipid conjugates of siRNA for specific tissue delivery |
| WO2021174071A1 (en) | 2020-02-29 | 2021-09-02 | President And Fellows Of Harvard College | Nanoswitch caliper trains for high-throughput, high-resolution structural analysis of biomolecules |
| CA3174079A1 (en) | 2020-05-26 | 2021-12-02 | Anastasia Khvorova | Synthetic oligonucleotides having regions of block and cluster modifications |
| IL309334A (en) | 2021-06-23 | 2024-02-01 | Univ Massachusetts | Anti-FLT1 optimized oligonucleotide compounds for the treatment of preeclampsia and other angiogenic disorders |
| US20250270552A1 (en) * | 2021-10-22 | 2025-08-28 | Hummingbird Dagnostics GmbH | Targeted inhibition of reverse transcription using antisense oligos |
| EP4499860A1 (en) | 2022-03-25 | 2025-02-05 | Bioo Scientific Corporation | Methods, compositions and kits for inhibiting formation of adapter dimers |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1253205A1 (en) | 2001-04-24 | 2002-10-30 | LION Bioscience AG | Method of blocking amplification of selected sequences |
| US20030211483A1 (en) * | 2002-05-09 | 2003-11-13 | Schroeder Benjamin G. | Methods for the enrichment of low-abundance polynucleotides |
| WO2007025281A2 (en) | 2005-08-24 | 2007-03-01 | Applera Corporation | A method to quantify sirnas, mirnas and polymorphic mirnas |
| WO2010126913A1 (en) | 2009-04-27 | 2010-11-04 | Gen-Probe Incorporated | Methods and kits for use in the selective amplification of target sequences |
| CN102791877A (zh) * | 2009-11-06 | 2012-11-21 | 酶学有限公司 | 使用双链核酸复合物与耐热聚合酶用于合成脱氧核糖核苷酸链的组合物和方法 |
| AU2011223789A1 (en) * | 2010-03-01 | 2012-09-20 | Caris Life Sciences Switzerland Holdings Gmbh | Biomarkers for theranostics |
| EP2591106A1 (en) | 2010-07-06 | 2013-05-15 | InteRNA Technologies B.V. | Mirna and its diagnostic and therapeutic uses in diseases or conditions associated with melanoma, or in diseases or conditions associated with activated braf pathway |
| EP3225698B1 (en) | 2011-09-06 | 2019-07-31 | Gen-Probe Incorporated | Closed nucleic acid structures |
| WO2014071315A1 (en) * | 2012-11-02 | 2014-05-08 | Life Technologies Corporation | Novel compositions, methods and kits for enhancing pcr specificity |
-
2016
- 2016-04-10 WO PCT/US2016/026846 patent/WO2016164866A1/en not_active Ceased
- 2016-04-10 JP JP2017553115A patent/JP6791875B2/ja not_active Expired - Fee Related
- 2016-04-10 AU AU2016246820A patent/AU2016246820B2/en active Active
- 2016-04-10 CA CA2982369A patent/CA2982369A1/en active Pending
- 2016-04-10 US US15/565,652 patent/US10480023B2/en active Active
- 2016-04-10 MX MX2017013022A patent/MX386064B/es unknown
- 2016-04-10 EP EP16777458.7A patent/EP3280805B1/en active Active
-
2017
- 2017-10-10 IL IL254972A patent/IL254972B/en active IP Right Grant
-
2019
- 2019-09-24 US US16/581,129 patent/US11781176B2/en active Active
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