JP6791875B2 - ｍｉＲＮＡをブロックするための方法 - Google Patents

ｍｉＲＮＡをブロックするための方法 Download PDF

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JP6791875B2
JP6791875B2 JP2017553115A JP2017553115A JP6791875B2 JP 6791875 B2 JP6791875 B2 JP 6791875B2 JP 2017553115 A JP2017553115 A JP 2017553115A JP 2017553115 A JP2017553115 A JP 2017553115A JP 6791875 B2 JP6791875 B2 JP 6791875B2
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blocking
mirna
nucleic acid
mir
rna
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JP2018513685A (ja
JP2018513685A5 (enExample
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マイヤーズ，リチャード・エム
ロバーツ，ブライアン・エス
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ハドソン アルファ インスティテュート フォー バイオテクノロジー
ハドソン アルファ インスティテュート フォー バイオテクノロジー
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    • C12Q2525/207—Modifications characterised by siRNA, miRNA
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    • C12Q2537/163—Reactions characterised by the reaction format or use of a specific feature the purpose or use of blocking probe

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JP2017553115A 2015-04-10 2016-04-10 ｍｉＲＮＡをブロックするための方法 Expired - Fee Related JP6791875B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562146015P 2015-04-10 2015-04-10
US62/146,015 2015-04-10
PCT/US2016/026846 WO2016164866A1 (en) 2015-04-10 2016-04-10 METHOD FOR BLOCKING miRNA

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JP2018513685A JP2018513685A (ja) 2018-05-31
JP2018513685A5 JP2018513685A5 (enExample) 2020-07-02
JP6791875B2 true JP6791875B2 (ja) 2020-11-25

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US (2) US10480023B2 (enExample)
EP (1) EP3280805B1 (enExample)
JP (1) JP6791875B2 (enExample)
AU (1) AU2016246820B2 (enExample)
CA (1) CA2982369A1 (enExample)
IL (1) IL254972B (enExample)
MX (1) MX386064B (enExample)
WO (1) WO2016164866A1 (enExample)

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EP3929293A3 (en) 2015-04-03 2022-03-16 University Of Massachusetts Fully stabilized asymmetric sirna
US11396650B2 (en) 2015-06-02 2022-07-26 Children's Medical Center Corporation Nucleic acid complexes for screening barcoded compounds
US12077807B2 (en) 2015-06-27 2024-09-03 The Research Foundation For The State University Of New York Compositions and methods for analyte detection using nanoswitches
WO2017030973A1 (en) 2015-08-14 2017-02-23 University Of Massachusetts Bioactive conjugates for oligonucleotide delivery
WO2017132669A1 (en) 2016-01-31 2017-08-03 University Of Massachusetts Branched oligonucleotides
US10287625B2 (en) * 2016-03-18 2019-05-14 Norgen Biotek Corp. Methods and kits for separating nucleic acids by size
WO2017165647A1 (en) 2016-03-23 2017-09-28 Children's Medical Center Corporation Rapid and sensitive detection and quantification of analytes in complex samples using polymer-based methods
WO2018031933A2 (en) 2016-08-12 2018-02-15 University Of Massachusetts Conjugated oligonucleotides
US12252507B2 (en) 2016-12-05 2025-03-18 Children's Medical Center Corporation Nucleic acid nanoswitch construction methods
AU2018224302B2 (en) * 2017-02-27 2024-08-29 Bioo Scientific Corporation Methods and kits for depleting undesired nucleic acids
WO2018237245A1 (en) 2017-06-23 2018-12-27 University Of Massachusetts TWO TAIL SELF-ADMINISTRATION SIRNA AND ASSOCIATED METHODS
CN111278844B (zh) * 2017-09-13 2023-12-19 贝克顿·迪金森公司 用于使用氧化铁颗粒提取核酸的方法和组合物
US11591636B2 (en) 2017-11-20 2023-02-28 Children's Medical Center Corporation Force-controlled nanoswitch assays for single-molecule detection in complex biological fluids
CN108676846B (zh) * 2018-05-25 2022-04-01 艾吉泰康生物科技(北京)有限公司 一种桥式寡核苷酸在文库目标区域捕获中的应用
BR112021002440A2 (pt) 2018-08-10 2021-05-04 University Of Massachusetts oligonucleotídeos modificados visando snps
WO2020041769A1 (en) 2018-08-23 2020-02-27 University Of Massachusetts O-methyl rich fully stabilized oligonucleotides
CN113614232A (zh) * 2019-01-18 2021-11-05 马萨诸塞大学 动态药代动力学修饰锚
KR20220047989A (ko) 2019-08-09 2022-04-19 유니버시티 오브 매사추세츠 Snp를 표적화하는 화학적으로 변형된 올리고뉴클레오타이드
US12365894B2 (en) 2019-09-16 2025-07-22 University Of Massachusetts Branched lipid conjugates of siRNA for specific tissue delivery
WO2021174071A1 (en) 2020-02-29 2021-09-02 President And Fellows Of Harvard College Nanoswitch caliper trains for high-throughput, high-resolution structural analysis of biomolecules
CA3174079A1 (en) 2020-05-26 2021-12-02 Anastasia Khvorova Synthetic oligonucleotides having regions of block and cluster modifications
IL309334A (en) 2021-06-23 2024-02-01 Univ Massachusetts Anti-FLT1 optimized oligonucleotide compounds for the treatment of preeclampsia and other angiogenic disorders
US20250270552A1 (en) * 2021-10-22 2025-08-28 Hummingbird Dagnostics GmbH Targeted inhibition of reverse transcription using antisense oligos
EP4499860A1 (en) 2022-03-25 2025-02-05 Bioo Scientific Corporation Methods, compositions and kits for inhibiting formation of adapter dimers

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EP1253205A1 (en) 2001-04-24 2002-10-30 LION Bioscience AG Method of blocking amplification of selected sequences
US20030211483A1 (en) * 2002-05-09 2003-11-13 Schroeder Benjamin G. Methods for the enrichment of low-abundance polynucleotides
WO2007025281A2 (en) 2005-08-24 2007-03-01 Applera Corporation A method to quantify sirnas, mirnas and polymorphic mirnas
WO2010126913A1 (en) 2009-04-27 2010-11-04 Gen-Probe Incorporated Methods and kits for use in the selective amplification of target sequences
CN102791877A (zh) * 2009-11-06 2012-11-21 酶学有限公司 使用双链核酸复合物与耐热聚合酶用于合成脱氧核糖核苷酸链的组合物和方法
AU2011223789A1 (en) * 2010-03-01 2012-09-20 Caris Life Sciences Switzerland Holdings Gmbh Biomarkers for theranostics
EP2591106A1 (en) 2010-07-06 2013-05-15 InteRNA Technologies B.V. Mirna and its diagnostic and therapeutic uses in diseases or conditions associated with melanoma, or in diseases or conditions associated with activated braf pathway
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WO2014071315A1 (en) * 2012-11-02 2014-05-08 Life Technologies Corporation Novel compositions, methods and kits for enhancing pcr specificity

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JP2018513685A (ja) 2018-05-31
MX2017013022A (es) 2018-03-15
AU2016246820B2 (en) 2021-08-12
US20180073066A1 (en) 2018-03-15
US10480023B2 (en) 2019-11-19
AU2016246820A1 (en) 2017-11-30
IL254972B (en) 2021-05-31
MX386064B (es) 2025-03-18
EP3280805B1 (en) 2020-12-16
EP3280805A1 (en) 2018-02-14
US11781176B2 (en) 2023-10-10
US20200024652A1 (en) 2020-01-23
EP3280805A4 (en) 2019-03-13
BR112017021854A2 (pt) 2018-07-10
IL254972A0 (en) 2017-12-31
CA2982369A1 (en) 2016-10-13
WO2016164866A1 (en) 2016-10-13

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