JP2018508509A5 - - Google Patents

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Publication number
JP2018508509A5
JP2018508509A5 JP2017544293A JP2017544293A JP2018508509A5 JP 2018508509 A5 JP2018508509 A5 JP 2018508509A5 JP 2017544293 A JP2017544293 A JP 2017544293A JP 2017544293 A JP2017544293 A JP 2017544293A JP 2018508509 A5 JP2018508509 A5 JP 2018508509A5
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JP
Japan
Prior art keywords
antibody
cancer
fully human
seq
fab fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2017544293A
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English (en)
Japanese (ja)
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JP2018508509A (ja
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Publication date
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Priority claimed from PCT/US2016/018897 external-priority patent/WO2016134358A1/en
Publication of JP2018508509A publication Critical patent/JP2018508509A/ja
Publication of JP2018508509A5 publication Critical patent/JP2018508509A5/ja
Withdrawn legal-status Critical Current

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JP2017544293A 2015-02-22 2016-02-22 Cd137に結合する抗体医薬 Withdrawn JP2018508509A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562119211P 2015-02-22 2015-02-22
US62/119,211 2015-02-22
PCT/US2016/018897 WO2016134358A1 (en) 2015-02-22 2016-02-22 Antibody therapeutics that bind cd137

Publications (2)

Publication Number Publication Date
JP2018508509A JP2018508509A (ja) 2018-03-29
JP2018508509A5 true JP2018508509A5 (enExample) 2019-04-04

Family

ID=56690285

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017544293A Withdrawn JP2018508509A (ja) 2015-02-22 2016-02-22 Cd137に結合する抗体医薬

Country Status (12)

Country Link
US (4) US10233251B2 (enExample)
EP (1) EP3258959A4 (enExample)
JP (1) JP2018508509A (enExample)
KR (1) KR20180016972A (enExample)
CN (1) CN107921104A (enExample)
AR (1) AR105313A1 (enExample)
AU (1) AU2016219772A1 (enExample)
CA (1) CA2977257A1 (enExample)
IL (1) IL254088A0 (enExample)
MX (1) MX2017010793A (enExample)
TW (1) TW201632559A (enExample)
WO (1) WO2016134358A1 (enExample)

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CN111511762B (zh) * 2017-08-21 2025-05-06 天演药业公司 抗cd137分子及其用途
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WO2019089753A2 (en) 2017-10-31 2019-05-09 Compass Therapeutics Llc Cd137 antibodies and pd-1 antagonists and uses thereof
TWI701259B (zh) * 2017-11-09 2020-08-11 大陸商上海懷越生物科技有限公司 4﹘1bb抗體及其製備方法和應用
EP3713961A2 (en) 2017-11-20 2020-09-30 Compass Therapeutics LLC Cd137 antibodies and tumor antigen-targeting antibodies and uses thereof
WO2019104716A1 (en) * 2017-12-01 2019-06-06 Adagene Inc. Methods for using cd137 ligand as biomarker for treatment with anti-cd137 antibody
US11548948B2 (en) 2017-12-19 2023-01-10 F-Star Therapeutics Limited FC binding fragments comprising a PD-L1 antigen-binding site
WO2019148445A1 (en) 2018-02-02 2019-08-08 Adagene Inc. Precision/context-dependent activatable antibodies, and methods of making and using the same
MX2020008791A (es) * 2018-02-23 2021-01-08 Bicycletx Ltd Ligandos de peptidos biciclicos multimericos.
MX2020009863A (es) 2018-03-23 2021-01-08 Lilly Co Eli Anticuerpos anti-cd137 para combinacion con anticuerpos anti-pd-l1.
MY202157A (en) * 2018-04-09 2024-04-09 Oricell Therapeutics Co Ltd Anti-pd-l1 antibody and use thereof
EP3797120A1 (en) 2018-05-21 2021-03-31 Compass Therapeutics LLC Compositions and methods for enhancing the killing of target cells by nk cells
WO2020006374A2 (en) * 2018-06-29 2020-01-02 Alector Llc Anti-sirp-beta1 antibodies and methods of use thereof
GB201811415D0 (en) 2018-07-12 2018-08-29 F Star Beta Ltd Anti-Mesothelin Anti bodies
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GB201811404D0 (en) * 2018-07-12 2018-08-29 F Star Beta Ltd Anti-CD137 Antibodies
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GB201811450D0 (en) 2018-07-12 2018-08-29 F Star Delta Ltd Mesothelin and CD137 binding molecules
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WO2020023556A1 (en) 2018-07-23 2020-01-30 Magenta Therapeutics, Inc. Use of anti-cd137 antibody drug conjugate (adc) in allogeneic cell therapy
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CN120623346A (zh) 2018-10-11 2025-09-12 因荷布瑞克斯生物科学公司 Pd-1单结构域抗体及其治疗组合物
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TW202214303A (zh) 2020-05-19 2022-04-16 德商百靈佳殷格翰國際股份有限公司 用於癌症治療之結合分子
CN113842456B (zh) * 2020-06-28 2022-07-26 上海齐鲁制药研究中心有限公司 一种抗人4-1bb的单克隆抗体制剂及其用途
TW202220677A (zh) * 2020-07-31 2022-06-01 日商中外製藥股份有限公司 含有表現嵌合受體之細胞的醫藥組成物
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EP3827019A1 (en) * 2018-07-24 2021-06-02 Inhibrx, Inc. Multispecific polypeptide constructs containing a constrained cd3 binding domain and a receptor binding region and methods of using the same
CN120623346A (zh) * 2018-10-11 2025-09-12 因荷布瑞克斯生物科学公司 Pd-1单结构域抗体及其治疗组合物

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