JP2018506986A5 - - Google Patents
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- JP2018506986A5 JP2018506986A5 JP2017546094A JP2017546094A JP2018506986A5 JP 2018506986 A5 JP2018506986 A5 JP 2018506986A5 JP 2017546094 A JP2017546094 A JP 2017546094A JP 2017546094 A JP2017546094 A JP 2017546094A JP 2018506986 A5 JP2018506986 A5 JP 2018506986A5
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- 239000001963 growth medium Substances 0.000 claims 14
- 238000000034 method Methods 0.000 claims 14
- 102000003974 Fibroblast growth factor 2 Human genes 0.000 claims 8
- 108090000379 Fibroblast growth factor 2 Proteins 0.000 claims 8
- 210000002901 mesenchymal stem cell Anatomy 0.000 claims 7
- 239000006143 cell culture medium Substances 0.000 claims 6
- 108010038512 Platelet-Derived Growth Factor Proteins 0.000 claims 5
- 102000010780 Platelet-Derived Growth Factor Human genes 0.000 claims 5
- 108010081589 Becaplermin Proteins 0.000 claims 4
- VBEQCZHXXJYVRD-GACYYNSASA-N uroanthelone Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(C)C)[C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCSC)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)CNC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CS)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(N)=O)C(C)C)[C@@H](C)CC)C1=CC=C(O)C=C1 VBEQCZHXXJYVRD-GACYYNSASA-N 0.000 claims 4
- 102000009024 Epidermal Growth Factor Human genes 0.000 claims 3
- 101800003838 Epidermal growth factor Proteins 0.000 claims 3
- 229940116977 epidermal growth factor Drugs 0.000 claims 3
- 241000283690 Bos taurus Species 0.000 claims 2
- 230000004663 cell proliferation Effects 0.000 claims 2
- 230000001605 fetal effect Effects 0.000 claims 2
- 238000000338 in vitro Methods 0.000 claims 2
- 239000002609 medium Substances 0.000 claims 2
- 230000001737 promoting effect Effects 0.000 claims 2
- 210000000130 stem cell Anatomy 0.000 claims 2
- 108091003079 Bovine Serum Albumin Proteins 0.000 claims 1
- 239000007640 basal medium Substances 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 239000012894 fetal calf serum Substances 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021042409A JP7410899B2 (ja) | 2015-03-04 | 2021-03-16 | 間葉系幹細胞の細胞培養法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2015900752 | 2015-03-04 | ||
| AU2015900752A AU2015900752A0 (en) | 2015-03-04 | Cell culture method | |
| AU2015900777 | 2015-03-05 | ||
| AU2015900777A AU2015900777A0 (en) | 2015-03-05 | Cell culture method | |
| PCT/EP2016/054640 WO2016139340A1 (en) | 2015-03-04 | 2016-03-04 | Cell culture method for mesenchymal stem cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021042409A Division JP7410899B2 (ja) | 2015-03-04 | 2021-03-16 | 間葉系幹細胞の細胞培養法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018506986A JP2018506986A (ja) | 2018-03-15 |
| JP2018506986A5 true JP2018506986A5 (OSRAM) | 2019-04-11 |
| JP6885870B2 JP6885870B2 (ja) | 2021-06-16 |
Family
ID=55453191
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017546094A Active JP6885870B2 (ja) | 2015-03-04 | 2016-03-04 | 間葉系幹細胞の細胞培養法 |
| JP2021042409A Active JP7410899B2 (ja) | 2015-03-04 | 2021-03-16 | 間葉系幹細胞の細胞培養法 |
| JP2023173585A Pending JP2024001179A (ja) | 2015-03-04 | 2023-10-05 | 間葉系幹細胞の細胞培養法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021042409A Active JP7410899B2 (ja) | 2015-03-04 | 2021-03-16 | 間葉系幹細胞の細胞培養法 |
| JP2023173585A Pending JP2024001179A (ja) | 2015-03-04 | 2023-10-05 | 間葉系幹細胞の細胞培養法 |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US20180037867A1 (OSRAM) |
| EP (2) | EP4008775A1 (OSRAM) |
| JP (3) | JP6885870B2 (OSRAM) |
| KR (1) | KR102635212B1 (OSRAM) |
| CN (2) | CN107567494A (OSRAM) |
| AU (2) | AU2016227607B2 (OSRAM) |
| BR (1) | BR112017018885A2 (OSRAM) |
| CA (1) | CA2977578C (OSRAM) |
| SG (1) | SG11201706886PA (OSRAM) |
| WO (1) | WO2016139340A1 (OSRAM) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3095856T3 (da) | 2008-09-16 | 2019-10-21 | Mayo Found Medical Education & Res | Sammensætninger med trombocytindhold |
| WO2012048099A2 (en) | 2010-10-08 | 2012-04-12 | Osiris Therapeutics, Inc. | Nanoparticle-loaded cells |
| CA3138143A1 (en) | 2014-05-16 | 2015-11-19 | Mayo Foundation For Medical Education And Research | Cell culture media compositions for primary cells |
| EP4008775A1 (en) | 2015-03-04 | 2022-06-08 | Mesoblast International Sàrl | Cell culture method for mesenchymal stem cells |
| EP3714038A1 (en) | 2017-11-22 | 2020-09-30 | Mesoblast International Sàrl | Cellular compositions and methods of treatment i |
| CN108251358B (zh) * | 2017-12-15 | 2021-10-26 | 广东药科大学 | 一种相同供体来源人间充质干细胞的多批次原代分离方法 |
| US20210115395A1 (en) * | 2018-03-28 | 2021-04-22 | Pluristem Ltd. | Methods for expanding adherent stromal cells and cells obtained thereby |
| CN108624554B (zh) * | 2018-05-14 | 2021-09-14 | 山东大学 | 一种非基因修饰光操控双向调节人脐带间充质干细胞增殖的方法 |
| WO2020060809A1 (en) * | 2018-09-17 | 2020-03-26 | Rejuvablast LLC | Combination grafts for tissue repair or regeneration applications |
| WO2020067443A1 (ja) * | 2018-09-27 | 2020-04-02 | テルモ株式会社 | 体細胞のシート化方法 |
| CN115997005A (zh) * | 2020-06-11 | 2023-04-21 | 迈索布拉斯特国际有限公司 | 间充质谱系前体或干细胞的3d培养 |
| CN117529234A (zh) * | 2021-03-10 | 2024-02-06 | 寺崎生物医学创新研究所 | 生产产品例如动物源性产品的方法和系统 |
| EP4304383A4 (en) * | 2021-03-10 | 2025-02-26 | Terasaki Institute For Biomedical Innovation | GROWTH FACTORS FOR LABORATORY-GROWN MEAT AND OTHER APPLICATIONS |
| WO2024121818A1 (en) | 2022-12-09 | 2024-06-13 | Mesoblast International Sarl | Method of treating heart failure in subjects with persistent inflammation |
| CN120641115A (zh) | 2022-12-09 | 2025-09-12 | 迈索布拉斯特国际有限公司 | 用细胞组合物治疗炎症的方法 |
| KR20250134601A (ko) | 2022-12-09 | 2025-09-11 | 메조블라스트 인터내셔널 에스에이알엘 | 조건화 배지 및 그 용도 |
| JP2025538783A (ja) | 2022-12-09 | 2025-11-28 | メゾブラスト・インターナショナル・エスアーエールエル | 事前承認された組成物及び細胞培養方法 |
| WO2024225602A1 (ko) * | 2023-04-24 | 2024-10-31 | 파미셀 주식회사 | 뉴클레오시드 함유 세포 배양배지 및 이를 이용한 세포 배양 방법 |
| WO2025046491A1 (en) | 2023-08-28 | 2025-03-06 | Mesoblast International Sàrl | Third line treatment for gvhd |
| WO2025062365A1 (en) | 2023-09-22 | 2025-03-27 | Mesoblast International Sárl | Mesenchymal lineage precursor or stem cells (mlpscs) for use in methods of treating congenital heart disease |
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| US5486359A (en) | 1990-11-16 | 1996-01-23 | Osiris Therapeutics, Inc. | Human mesenchymal stem cells |
| EP0978259B1 (de) | 1991-08-12 | 2002-02-20 | Karl Storz GmbH & Co. KG | Hochfrequenzchirurgiegenerator mit einer einstellbaren Ausgangsleistung |
| US5814464A (en) | 1994-10-07 | 1998-09-29 | Regeneron Pharma | Nucleic acids encoding TIE-2 ligand-2 |
| US6277372B1 (en) | 1994-11-08 | 2001-08-21 | Diacrin, Inc. | Porcine neural cells and their use in treatment of neurological deficits due to neurodegenerative diseases |
| US6204053B1 (en) | 1994-11-08 | 2001-03-20 | Diacrin, Inc. | Porcine cortical cells and their use in treatment of neurological deficits due to neurodegenerative diseases |
| ATE273384T1 (de) | 1995-04-06 | 2004-08-15 | Regeneron Pharma | Tie-2 liganden, herstellungsverfahren und verwendung |
| AU5734998A (en) | 1997-01-10 | 1998-08-03 | Life Technologies, Inc. | Embryonic stem cell serum replacement |
| US5968829A (en) | 1997-09-05 | 1999-10-19 | Cytotherapeutics, Inc. | Human CNS neural stem cells |
| RU2272839C2 (ru) * | 1998-11-09 | 2006-03-27 | Консорцио Пер Ла Джестионе Дель Чентро Ди Биотекнолоджие Аванцате | Бессывороточная среда для культуры клеток, используемых для реконструкции костных и хрящевых сегментов (варианты) |
| AU2003901668A0 (en) | 2003-03-28 | 2003-05-01 | Medvet Science Pty. Ltd. | Non-haemopoietic precursor cells |
| WO2001028574A2 (en) | 1999-10-20 | 2001-04-26 | Stem Cells, Inc. | Methods for inducing in vivo proliferation and migration of transplanted progenitor cells in the brain |
| US7439064B2 (en) * | 2000-03-09 | 2008-10-21 | Wicell Research Institute, Inc. | Cultivation of human embryonic stem cells in the absence of feeder cells or without conditioned medium |
| JP2004528021A (ja) | 2001-02-14 | 2004-09-16 | アンスロジェネシス コーポレーション | 分娩後の哺乳動物の胎盤、その使用およびそれに由来する胎盤幹細胞 |
| ES2545899T3 (es) | 2001-02-14 | 2015-09-16 | Anthrogenesis Corporation | Placenta post-parto de mamíferos, su uso y células madre placentarias de la misma |
| JP2005500847A (ja) | 2001-08-24 | 2005-01-13 | アドバンスド セル テクノロジー、インコーポレイテッド | 分化誘導薬の同定のためのスクリーニング検定及び細胞治療用の分化細胞の調製 |
| MXPA04007732A (es) | 2002-02-13 | 2004-10-15 | Anthrogenesis Corp | Celulas madre similares a las embrionarias, derivadas de la placenta de mamiferos despues del parto y usos y metodos de tratamiento usando dichas celulas. |
| WO2003102134A2 (en) | 2002-05-28 | 2003-12-11 | Becton, Dickinson And Company | Pancreatic acinar cells into insulin producing cells |
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| JP2008148643A (ja) * | 2006-12-19 | 2008-07-03 | Olympus Corp | 無血清培地および幹細胞の培養方法 |
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| US20110236971A2 (en) * | 2007-09-25 | 2011-09-29 | Maksym Vodyanyk | Generation of Clonal Mesenchymal Progenitors and Mesenchymal Stem Cell Lines Under Serum-Free Conditions |
| KR101224588B1 (ko) * | 2008-01-24 | 2013-01-22 | 삼성전자주식회사 | 멀티포인트 스트록을 감지하기 위한 ｕｉ 제공방법 및 이를적용한 멀티미디어 기기 |
| US20110110888A1 (en) | 2008-06-27 | 2011-05-12 | Hai-Qing Xian | Scaffold Coated and/or Impregnated with at Least One Bioactive Agent for Tissue Repair and Other Medical Applications |
| US20100055078A1 (en) * | 2008-08-15 | 2010-03-04 | The Government of the U.S.A, as represented by the Department of Veterans Affairs | Methods of making a transplantable bone repair system using multipotent stem cells |
| US20110212523A1 (en) | 2008-11-11 | 2011-09-01 | Yukio Kato | Differentiation-inducing culture medium additive and use thereof |
| US20100158878A1 (en) | 2008-12-23 | 2010-06-24 | Alexandra Capela | Target populations of oligodendrocyte precursor cells and methods of making and using same |
| US10894944B2 (en) | 2009-04-10 | 2021-01-19 | Monash University | Cell culture media |
| US9394521B2 (en) * | 2010-03-10 | 2016-07-19 | Two Cells Co., Ltd. | Cell preparation containing mesenchymal stem cells, and method for producing same |
| AU2011265723A1 (en) * | 2010-06-17 | 2013-01-10 | Stemrd, Inc. | Serum-free chemically defined cell culture medium |
| CA2821065C (en) * | 2011-01-12 | 2021-05-18 | Tsuneo KIDO | Culture method to obtain and maintain a pure or enriched population of mammalian neural stem cells and/or neural progenitor cells that are prone to differentiate into oligodendrocyte-lineage cells in vitro |
| KR101523040B1 (ko) * | 2012-06-26 | 2015-05-26 | 라정찬 | 고농도의 줄기세포 제조방법 |
| WO2014082685A1 (en) * | 2012-11-30 | 2014-06-05 | Swiss Stem Cell Foundation | Serum-free medium for human mesenchymal stem cells |
| CN103396984B (zh) * | 2013-07-25 | 2016-02-10 | 宗兆文 | 一种利用皮肤来源的祖细胞制备组织工程脊髓的方法 |
| EP4008775A1 (en) | 2015-03-04 | 2022-06-08 | Mesoblast International Sàrl | Cell culture method for mesenchymal stem cells |
-
2016
- 2016-03-04 EP EP21205011.6A patent/EP4008775A1/en active Pending
- 2016-03-04 KR KR1020177025840A patent/KR102635212B1/ko active Active
- 2016-03-04 EP EP16707810.4A patent/EP3265554B1/en active Active
- 2016-03-04 SG SG11201706886PA patent/SG11201706886PA/en unknown
- 2016-03-04 CA CA2977578A patent/CA2977578C/en active Active
- 2016-03-04 CN CN201680025469.8A patent/CN107567494A/zh active Pending
- 2016-03-04 US US15/553,115 patent/US20180037867A1/en not_active Abandoned
- 2016-03-04 JP JP2017546094A patent/JP6885870B2/ja active Active
- 2016-03-04 CN CN202111251410.XA patent/CN113957043A/zh active Pending
- 2016-03-04 BR BR112017018885A patent/BR112017018885A2/pt not_active Application Discontinuation
- 2016-03-04 AU AU2016227607A patent/AU2016227607B2/en active Active
- 2016-03-04 WO PCT/EP2016/054640 patent/WO2016139340A1/en not_active Ceased
-
2019
- 2019-10-11 US US16/599,271 patent/US11685899B2/en active Active
-
2021
- 2021-03-16 JP JP2021042409A patent/JP7410899B2/ja active Active
- 2021-10-19 AU AU2021254538A patent/AU2021254538B2/en active Active
-
2023
- 2023-03-21 US US18/124,346 patent/US12215352B2/en active Active
- 2023-10-05 JP JP2023173585A patent/JP2024001179A/ja active Pending
-
2024
- 2024-12-24 US US19/001,125 patent/US20250129337A1/en active Pending
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