JP2017506511A5 - - Google Patents
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- JP2017506511A5 JP2017506511A5 JP2016551725A JP2016551725A JP2017506511A5 JP 2017506511 A5 JP2017506511 A5 JP 2017506511A5 JP 2016551725 A JP2016551725 A JP 2016551725A JP 2016551725 A JP2016551725 A JP 2016551725A JP 2017506511 A5 JP2017506511 A5 JP 2017506511A5
- Authority
- JP
- Japan
- Prior art keywords
- medium
- ldl
- mesenchymal stem
- medium according
- lipoprotein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
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- 239000002609 medium Substances 0.000 claims 24
- 108010007622 LDL Lipoproteins Proteins 0.000 claims 7
- 102000007330 LDL Lipoproteins Human genes 0.000 claims 7
- 210000002901 mesenchymal stem cell Anatomy 0.000 claims 7
- 102000018233 Fibroblast Growth Factor Human genes 0.000 claims 4
- 108050007372 Fibroblast Growth Factor Proteins 0.000 claims 4
- 108090000379 Fibroblast growth factor 2 Proteins 0.000 claims 4
- 108010062497 VLDL Lipoproteins Proteins 0.000 claims 4
- 229940126864 fibroblast growth factor Drugs 0.000 claims 4
- 239000001963 growth medium Substances 0.000 claims 4
- 239000002245 particle Substances 0.000 claims 4
- 102000004895 Lipoproteins Human genes 0.000 claims 3
- 108090001030 Lipoproteins Proteins 0.000 claims 3
- 102000004887 Transforming Growth Factor beta Human genes 0.000 claims 3
- 108090001012 Transforming Growth Factor beta Proteins 0.000 claims 3
- 102000003974 Fibroblast growth factor 2 Human genes 0.000 claims 2
- 102100024785 Fibroblast growth factor 2 Human genes 0.000 claims 2
- 108010010234 HDL Lipoproteins Proteins 0.000 claims 2
- 102000015779 HDL Lipoproteins Human genes 0.000 claims 2
- 108010046315 IDL Lipoproteins Proteins 0.000 claims 2
- 102000009618 Transforming Growth Factors Human genes 0.000 claims 2
- 108010009583 Transforming Growth Factors Proteins 0.000 claims 2
- 239000007640 basal medium Substances 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 108091008012 small dense LDL Proteins 0.000 claims 2
- ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 claims 2
- 102000008100 Human Serum Albumin Human genes 0.000 claims 1
- 108091006905 Human Serum Albumin Proteins 0.000 claims 1
- 108010033266 Lipoprotein(a) Proteins 0.000 claims 1
- 102000057248 Lipoprotein(a) Human genes 0.000 claims 1
- 210000000577 adipose tissue Anatomy 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 210000000988 bone and bone Anatomy 0.000 claims 1
- 210000000845 cartilage Anatomy 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 claims 1
- 229960003957 dexamethasone Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003102 growth factor Substances 0.000 claims 1
- 229910052711 selenium Inorganic materials 0.000 claims 1
- 239000011669 selenium Substances 0.000 claims 1
- 239000012679 serum free medium Substances 0.000 claims 1
- 210000000130 stem cell Anatomy 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 claims 1
- 230000002792 vascular Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14155263 | 2014-02-14 | ||
| EP14155263.8 | 2014-02-14 | ||
| PCT/EP2015/053223 WO2015121471A1 (en) | 2014-02-14 | 2015-02-16 | Serum-free medium |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017506511A JP2017506511A (ja) | 2017-03-09 |
| JP2017506511A5 true JP2017506511A5 (OSRAM) | 2017-11-16 |
Family
ID=50101793
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016551725A Ceased JP2017506511A (ja) | 2014-02-14 | 2015-02-16 | 無血清培地 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US10472605B2 (OSRAM) |
| EP (1) | EP3074505B1 (OSRAM) |
| JP (1) | JP2017506511A (OSRAM) |
| CN (1) | CN106062179A (OSRAM) |
| WO (1) | WO2015121471A1 (OSRAM) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20180362933A1 (en) * | 2015-12-03 | 2018-12-20 | Takara Bio Inc. | Method for producing mesenchymal stem cells |
| CN109415680B (zh) * | 2016-05-18 | 2022-08-16 | 学校法人庆应义塾 | 类器官培养用细胞培养基、培养方法及类器官 |
| CN112322580B (zh) * | 2017-04-28 | 2022-03-22 | 北京赛斯达生物技术有限公司 | 一种间充质干细胞无血清培养基的应用 |
| KR102144593B1 (ko) * | 2017-06-07 | 2020-08-13 | 주식회사 엑소스템텍 | 인간줄기세포 유래 엑소좀을 포함하는 세포 배양용 무혈청 배지 조성물 |
| KR102185697B1 (ko) * | 2017-10-20 | 2020-12-03 | 본 테라퓨틱스 소시에테아노님 | 중간엽 줄기 세포의 분화 방법 |
| US20210123025A1 (en) * | 2018-07-03 | 2021-04-29 | Universidad Del País Vasco - Euskal Herriko Unibertsitatea | Cellular aggregates for use in vascularisation therapy |
| KR102337954B1 (ko) * | 2018-08-16 | 2021-12-10 | 차의과학대학교 산학협력단 | 뇌졸중 치료용 조성물 및 이를 스크리닝하는 방법 |
| AU2020310855A1 (en) * | 2019-07-08 | 2022-03-03 | Life Technologies Corporation | Compositions and methods for enhancing cell culture |
| CN114286860A (zh) * | 2019-08-29 | 2022-04-05 | 味之素株式会社 | 由含有间充质干细胞的生物来源细胞试样制造间充质干细胞的方法 |
| JP2021040551A (ja) * | 2019-09-11 | 2021-03-18 | 富士フイルム株式会社 | 培地組成物、キット、間葉系幹細胞組成物の製造方法、間葉系幹細胞組成物、間葉系幹細胞、細胞培養上清および細胞外小胞 |
| CN112342181B (zh) * | 2020-03-26 | 2021-12-24 | 中国人民解放军总医院第四医学中心 | 基于数控激光辐射的非入侵式的细胞成图案方法及系统 |
| JP7521738B2 (ja) * | 2020-05-18 | 2024-07-24 | キヤノン株式会社 | 目的細胞の生産方法、目的細胞による生産物の生産方法、および無血清培地 |
| CN113621567B (zh) * | 2021-07-09 | 2024-01-30 | 生物岛实验室 | 组合物及其应用、干细胞培养基及干细胞的培养方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61277623A (ja) * | 1985-05-10 | 1986-12-08 | マイルス・ラボラトリ−ス・インコ−ポレ−テツド | 哺乳動物の血漿または血清あるいはその分画からコレステロールに富んだ分画を単離しかつ精製する方法 |
| US5908782A (en) * | 1995-06-05 | 1999-06-01 | Osiris Therapeutics, Inc. | Chemically defined medium for human mesenchymal stem cells |
| WO1998004681A2 (en) | 1996-07-25 | 1998-02-05 | Genzyme Corporation | Chondrocyte media formulations and culture procedures |
| TWI239352B (en) | 1997-07-23 | 2005-09-11 | Takara Bio Inc | Gene transfer method with the use of serum-free medium |
| DE60037819T2 (de) | 1999-08-27 | 2009-01-08 | Invitrogen Corp., Carlsbad | Metallbindende verbindungen und deren verwendung in zusammensetzungen für zellkulturmedien |
| JP2005512592A (ja) | 2001-12-21 | 2005-05-12 | マウント・シナイ・ホスピタル | 細胞性組成物ならびに細胞性組成物の作製法および細胞性組成物の使用法 |
| WO2005113751A1 (en) | 2004-05-14 | 2005-12-01 | Becton, Dickinson And Company | Cell culture environments for the serum-free expansion of mesenchymal stem cells |
| KR101107835B1 (ko) * | 2006-01-13 | 2012-02-09 | 가부시키가이샤 투셀 | 동물 세포의 무혈청 배양에 사용하기 위한 배양 배지 첨가물, 키트 및 이의 용도 |
| EP2545928B1 (en) | 2010-03-10 | 2016-07-20 | Two Cells Co., Ltd | Cell preparation containing mesenchymal stem cells, and method for producing same |
| GB201117469D0 (en) * | 2011-10-10 | 2011-11-23 | Cell Guidance Systems Ltd | Culture media for pluripotent stem cells |
-
2015
- 2015-02-16 WO PCT/EP2015/053223 patent/WO2015121471A1/en not_active Ceased
- 2015-02-16 EP EP15707303.2A patent/EP3074505B1/en active Active
- 2015-02-16 JP JP2016551725A patent/JP2017506511A/ja not_active Ceased
- 2015-02-16 CN CN201580008299.8A patent/CN106062179A/zh active Pending
- 2015-02-16 US US15/118,569 patent/US10472605B2/en active Active
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