JP2018506981A - 抗dll3キメラ抗原受容体および使用方法 - Google Patents

抗dll3キメラ抗原受容体および使用方法 Download PDF

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JP2018506981A
JP2018506981A JP2017544615A JP2017544615A JP2018506981A JP 2018506981 A JP2018506981 A JP 2018506981A JP 2017544615 A JP2017544615 A JP 2017544615A JP 2017544615 A JP2017544615 A JP 2017544615A JP 2018506981 A JP2018506981 A JP 2018506981A
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dll3
cells
antibody
cell
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エスカルプ,ポール・アンソニー
ダイラ,スコット・ジェイ
リウ,デイビッド
スタル,ロバート・エイ
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アッヴィ・ステムセントルクス・エル・エル・シー
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JP2017544615A 2015-02-23 2016-02-23 抗dll3キメラ抗原受容体および使用方法 Pending JP2018506981A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201562119793P 2015-02-23 2015-02-23
US62/119,793 2015-02-23
US201562241662P 2015-10-14 2015-10-14
US62/241,662 2015-10-14
US201662296560P 2016-02-17 2016-02-17
US62/296,560 2016-02-17
PCT/US2016/019192 WO2016138038A1 (en) 2015-02-23 2016-02-23 Anti-dll3 chimeric antigen receptors and methods of use

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JP2018506981A true JP2018506981A (ja) 2018-03-15
JP2018506981A5 JP2018506981A5 (https=) 2019-04-04

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EP (1) EP3261650A4 (https=)
JP (1) JP2018506981A (https=)
KR (1) KR20170120158A (https=)
CN (1) CN107405362A (https=)
BR (1) BR112017017927A2 (https=)
CA (1) CA2977502A1 (https=)
CL (1) CL2017002150A1 (https=)
CO (1) CO2017008804A2 (https=)
CR (1) CR20170436A (https=)
DO (1) DOP2017000199A (https=)
EA (1) EA201791884A1 (https=)
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HK (1) HK1249405A1 (https=)
IL (1) IL254068A0 (https=)
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PH (1) PH12017501521A1 (https=)
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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021520788A (ja) * 2018-04-10 2021-08-26 アムジエン・インコーポレーテツド Dll3に対するキメラ受容体及びその使用方法
JP2021528047A (ja) * 2018-05-08 2021-10-21 フェインズ セラピューティクス,インコーポレーテッド 抗dll3抗体及びその使用
JP2022504822A (ja) * 2018-10-11 2022-01-13 インヒブルクス インコーポレイテッド Dll3シングルドメイン抗体およびその治療用組成物
JP2022523781A (ja) * 2019-03-01 2022-04-26 アロジーン セラピューティクス,インコーポレイテッド Dll3標的化キメラ抗原受容体および結合剤
JP2022542543A (ja) * 2019-07-17 2022-10-05 ナンジン レジェンド バイオテック カンパニー,リミテッド 抗dll3キメラ抗原受容体及びその使用
JP2023548590A (ja) * 2020-11-06 2023-11-17 ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム 小細胞肺がんの分類と治療のための方法およびシステム

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GB201403972D0 (en) 2014-03-06 2014-04-23 Ucl Business Plc Chimeric antigen receptor
EA201792573A1 (ru) 2015-05-21 2018-04-30 Харпун Терапьютикс, Инк. Триспецифические связанные белки и способы их применения
JP7101621B2 (ja) 2016-05-20 2022-07-15 ハープーン セラピューティクス,インク. 単一ドメイン血清アルブミン結合タンパク質
SG11201907299XA (en) 2017-02-08 2019-09-27 Dragonfly Therapeutics Inc Multi-specific binding proteins for activation of natural killer cells and therapeutic uses thereof to treat cancer
CN108395482B (zh) 2017-02-08 2021-02-05 西比曼生物科技(香港)有限公司 一种靶向cd20抗原嵌合抗原受体的构建及其工程化t细胞的活性鉴定
IL268755B2 (en) 2017-02-20 2025-12-01 Dragonfly Therapeutics Inc Proteins that bind her2, nkg2d, and cd16
JP2020530554A (ja) 2017-07-20 2020-10-22 シートムエックス セラピューティクス,インコーポレイテッド 活性化抗体の特性を定性的および/または定量的に分析する方法およびその使用
KR102172092B1 (ko) 2017-09-19 2020-10-30 주식회사 엘지화학 열가소성 수지 조성물, 이의 제조방법 및 성형품
HRP20241268T1 (hr) 2017-10-13 2024-12-06 Harpoon Therapeutics, Inc. Trispecifični proteini i postupci primjene
IL315737A (en) 2017-10-13 2024-11-01 Harpoon Therapeutics Inc B-cell maturation antigen-binding proteins
JP2021500552A (ja) * 2017-10-20 2021-01-07 ナントバイオ,インコーポレイテッド 膀胱癌免疫療法のモニタリング方法
DK3749346T3 (da) 2018-02-08 2024-09-09 Dragonfly Therapeutics Inc Antistof variable domænekombinationer rettet mod nkg2d-receptoren
EA202091887A1 (ru) 2018-02-08 2020-10-23 Драгонфлай Терапьютикс, Инк. Комбинированная терапия рака с применением мультиспецифических связывающих белков, которые активируют естественные клетки-киллеры
CN111989108B (zh) * 2018-02-13 2024-07-16 嵌合体生物工程公司 利用rna去稳定元件协调基因表达
WO2019164930A1 (en) 2018-02-20 2019-08-29 Dragonfly Therapeutics, Inc. Multi-specific binding proteins that bind cd33, nkg2d, and cd16, and methods of use
US20220025037A1 (en) * 2018-04-03 2022-01-27 Dragonfly Therapeutics, Inc. Antibody variable domains targeting dll3, and use thereof
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