|
US11136557B2
(en)
|
2013-05-31 |
2021-10-05 |
The Regents Of The University Of California |
Adeno-associated virus variants and methods of use thereof
|
|
JP7046828B2
(ja)
|
2016-04-15 |
2022-04-04 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
滲出型加齢性黄斑変性の治療のための組成物
|
|
EP3827812B1
(en)
|
2016-07-29 |
2025-10-29 |
The Regents of the University of California |
Adeno-associated virus virions with variant capsid and methods of use thereof
|
|
WO2018045347A1
(en)
*
|
2016-09-02 |
2018-03-08 |
Spark Therapeutics, Inc. |
Methods and vectors for treating cns disorders
|
|
WO2019006182A1
(en)
*
|
2017-06-30 |
2019-01-03 |
The Regents Of The University Of California |
VIRIONS OF ADENO-ASSOCIATED VIRUSES OF CAPSID VARIANTS AND METHODS OF USE THEREOF
|
|
JP7221275B2
(ja)
|
2017-08-03 |
2023-02-13 |
ボイジャー セラピューティクス インコーポレイテッド |
Aavを送達するための組成物および方法
|
|
JP2020534788A
(ja)
|
2017-08-28 |
2020-12-03 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
アデノ随伴ウイルスカプシド変異体及びその使用方法
|
|
NZ763617A
(en)
*
|
2017-10-16 |
2026-01-30 |
Vigeneron Gmbh |
Aav vectors
|
|
SG11202003778QA
(en)
*
|
2017-11-13 |
2020-05-28 |
Univ California |
Compositions and methods for enhancing visual function
|
|
MA50877A
(fr)
|
2017-11-21 |
2020-09-30 |
Bayer Healthcare Llc |
Matériaux et méthodes pour le traitement de la rétinite pigmentaire autosomique dominante
|
|
CN112105630A
(zh)
*
|
2018-02-15 |
2020-12-18 |
T·比约尔克隆德 |
经修饰的病毒衣壳
|
|
US12558434B2
(en)
|
2018-02-20 |
2026-02-24 |
The Trustees Of The University Of Pennsylvania |
Compositions for treatment of wet age-related macular degeneration
|
|
US12421525B2
(en)
|
2018-02-28 |
2025-09-23 |
University of Pittsburgh—of the Commonwealth System of Higher Education |
Conjugates comprising AAVs and CAS9 polypeptides
|
|
SG11202011296VA
(en)
|
2018-05-15 |
2020-12-30 |
Voyager Therapeutics Inc |
Compositions and methods for the treatment of parkinson's disease
|
|
TW202015742A
(zh)
|
2018-05-15 |
2020-05-01 |
美商航海家醫療公司 |
投遞腺相關病毒(aav)之組成物和方法
|
|
US12060567B2
(en)
|
2018-06-13 |
2024-08-13 |
Voyager Therapeutics, Inc. |
Engineered untranslated regions (UTR) for AAV production
|
|
AU2019310459A1
(en)
|
2018-07-24 |
2021-02-18 |
Voyager Therapeutics, Inc. |
Systems and methods for producing gene therapy formulations
|
|
US12281321B2
(en)
|
2018-09-28 |
2025-04-22 |
Voyager Therapeutics, Inc. |
Frataxin expression constructs having engineered promoters and methods of use thereof
|
|
WO2020072849A1
(en)
|
2018-10-04 |
2020-04-09 |
Voyager Therapeutics, Inc. |
Methods for measuring the titer and potency of viral vector particles
|
|
WO2020072844A1
(en)
|
2018-10-05 |
2020-04-09 |
Voyager Therapeutics, Inc. |
Engineered nucleic acid constructs encoding aav production proteins
|
|
WO2020077165A1
(en)
|
2018-10-12 |
2020-04-16 |
Voyager Therapeutics, Inc. |
Compositions and methods for delivery of aav
|
|
CA3116701A1
(en)
|
2018-10-15 |
2020-04-23 |
Voyager Therapeutics, Inc. |
Expression vectors for large-scale production of raav in the baculovirus/sf9 system
|
|
JP2022522995A
(ja)
|
2019-01-18 |
2022-04-21 |
ボイジャー セラピューティクス インコーポレイテッド |
Aav粒子を生成するための方法及びシステム
|
|
EP4667578A3
(en)
*
|
2019-04-03 |
2026-04-01 |
REGENXBIO Inc. |
Gene therapy for eye pathologies
|
|
KR20210148333A
(ko)
*
|
2019-04-08 |
2021-12-07 |
더 칠드런스 호스피탈 오브 필라델피아 |
Tpp1을 발현하는 aav의 투여를 통한 눈의 리소좀 축적 질환 치료
|
|
EP3962536A1
(en)
|
2019-04-29 |
2022-03-09 |
Voyager Therapeutics, Inc. |
Systems and methods for producing baculoviral infected insect cells (biics) in bioreactors
|
|
WO2020227515A1
(en)
|
2019-05-07 |
2020-11-12 |
Voyager Therapeutics, Inc. |
Compositions and methods for the vectored augmentation of protein destruction, expression and/or regulation
|
|
WO2021030125A1
(en)
|
2019-08-09 |
2021-02-18 |
Voyager Therapeutics, Inc. |
Cell culture medium for use in producing gene therapy products in bioreactors
|
|
TW202122582A
(zh)
|
2019-08-26 |
2021-06-16 |
美商航海家醫療公司 |
病毒蛋白之控制表現
|
|
US20220333133A1
(en)
|
2019-09-03 |
2022-10-20 |
Voyager Therapeutics, Inc. |
Vectorized editing of nucleic acids to correct overt mutations
|
|
CN114729009A
(zh)
*
|
2019-10-31 |
2022-07-08 |
伯尔尼大学 |
用于眼部基因递送的aav载体变体
|
|
CN113025618B
(zh)
*
|
2019-12-24 |
2024-02-06 |
朗信启昇(苏州)生物制药有限公司 |
一种x连锁遗传性视网膜劈裂症的基因治疗方案与应用
|
|
WO2021207500A2
(en)
*
|
2020-04-08 |
2021-10-14 |
President And Fellows Of Harvard College |
TGFβ THERAPY FOR OCULAR AND NEURODEGENERATIVE DISEASES
|
|
CN116096734A
(zh)
|
2020-05-13 |
2023-05-09 |
沃雅戈治疗公司 |
Aav衣壳的向性的重定向
|
|
WO2021247995A2
(en)
|
2020-06-04 |
2021-12-09 |
Voyager Therapeutics, Inc. |
Compositions and methods of treating neuropathic pain
|
|
JP7842082B2
(ja)
*
|
2020-07-21 |
2026-04-07 |
エフティージェン コーポレーション |
眼疾患を処置するための組成物および方法
|
|
US20230285596A1
(en)
|
2020-07-27 |
2023-09-14 |
Voyager Therapeutics, Inc |
Compositions and methods for the treatment of niemann-pick type c1 disease
|
|
BR112023001456A2
(pt)
|
2020-07-27 |
2023-04-11 |
Voyager Therapeutics Inc |
Composições e métodos para o tratamento de distúrbios neurológicos relacionados à deficiência de beta glicosilceramidase
|
|
WO2022032153A1
(en)
|
2020-08-06 |
2022-02-10 |
Voyager Therapeutics, Inc. |
Cell culture medium for use in producing gene therapy products in bioreactors
|
|
US20240141377A1
(en)
|
2021-03-03 |
2024-05-02 |
Voyager Therapeutics, Inc. |
Controlled expression of viral proteins
|
|
US20240141378A1
(en)
|
2021-03-03 |
2024-05-02 |
Voyager Therapeutics, Inc. |
Controlled expression of viral proteins
|
|
CN113121655B
(zh)
*
|
2021-04-19 |
2021-11-19 |
上海信致医药科技有限公司 |
眼部和肌肉特异靶向型腺相关病毒载体及其应用
|
|
MX2023012722A
(es)
*
|
2021-04-27 |
2023-11-08 |
Massachusetts Gen Hospital |
Capsides de aav y usos de las mismas.
|
|
US20240382617A1
(en)
*
|
2021-09-21 |
2024-11-21 |
Capsida Biotherapeutics, Inc. |
Virus compositions to efficiently target the nervous system and the lungs
|
|
CA3238867A1
(en)
|
2021-11-29 |
2023-06-01 |
Shanghai Regenelead Therapies Co., Ltd. |
Aadc/gdnf polynucleotide, and use thereof in treating parkinson's disease
|
|
CN114195859B
(zh)
*
|
2021-12-10 |
2022-11-18 |
和元生物技术(上海)股份有限公司 |
一种适用于特异感染u251细胞的腺相关病毒突变体
|
|
EP4479414A1
(en)
|
2022-02-17 |
2024-12-25 |
Skyline Therapeutics Limited |
Recombinant adeno-associated virus with modified aav capsid polypeptides
|
|
CN118660913A
(zh)
|
2022-02-21 |
2024-09-17 |
上海瑞宏迪医药有限公司 |
Vegf结合分子及其医药用途
|
|
CN119894920A
(zh)
|
2022-07-22 |
2025-04-25 |
上海天泽云泰生物医药有限公司 |
用于靶向神经系统的新型aav衣壳及其用途
|
|
US20260085328A1
(en)
|
2022-09-08 |
2026-03-26 |
Voyager Therapeutics, Inc. |
Controlled expression of viral proteins
|
|
EP4688808A1
(en)
*
|
2023-04-04 |
2026-02-11 |
Children's Medical Research Institute |
Aav capsids and vectors for transduction of cells of the peripheral nervous system
|
|
WO2025040166A1
(zh)
|
2023-08-23 |
2025-02-27 |
上海瑞宏迪医药有限公司 |
药物组合物及其用途
|
|
WO2025214404A1
(en)
|
2024-04-10 |
2025-10-16 |
Skyline Therapeutics (Shanghai) Co., Ltd. |
Optogenetic modulation for vision restoration
|
|
WO2025214408A1
(en)
|
2024-04-10 |
2025-10-16 |
Skyline Therapeutics (Shanghai) Co., Ltd. |
Optogenetic modulation for vision restoration
|
|
WO2026005189A1
(ko)
*
|
2024-06-27 |
2026-01-02 |
이엔셀 주식회사 |
안구 세포 또는 조직을 표적하는 펩타이드 및 이를 포함하는 바이러스 캡시드 단백질 및 바이러스 벡터
|
|
KR102901502B1
(ko)
*
|
2024-06-27 |
2025-12-18 |
이엔셀 주식회사 |
안구 세포 또는 조직을 표적하는 펩타이드 및 이를 포함하는 바이러스 캡시드 단백질 및 바이러스 벡터
|
|
CN119039401B
(zh)
*
|
2024-08-19 |
2025-04-11 |
广州派真生物技术有限公司 |
腺相关病毒突变体及其应用
|