JP2018506585A5 - - Google Patents
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- JP2018506585A5 JP2018506585A5 JP2017560479A JP2017560479A JP2018506585A5 JP 2018506585 A5 JP2018506585 A5 JP 2018506585A5 JP 2017560479 A JP2017560479 A JP 2017560479A JP 2017560479 A JP2017560479 A JP 2017560479A JP 2018506585 A5 JP2018506585 A5 JP 2018506585A5
- Authority
- JP
- Japan
- Prior art keywords
- raav
- nucleic acid
- disease
- raav particle
- optionally
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021129519A JP2021178861A (ja) | 2015-02-10 | 2021-08-06 | 線条体および皮質へのウイルス粒子の強化された送達 |
| JP2023018846A JP2023058630A (ja) | 2015-02-10 | 2023-02-10 | 線条体および皮質へのウイルス粒子の強化された送達 |
| JP2024228114A JP2025060823A (ja) | 2015-02-10 | 2024-12-25 | 線条体および皮質へのウイルス粒子の強化された送達 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562114544P | 2015-02-10 | 2015-02-10 | |
| US62/114,544 | 2015-02-10 | ||
| US201562220997P | 2015-09-19 | 2015-09-19 | |
| US62/220,997 | 2015-09-19 | ||
| PCT/US2016/017210 WO2016130591A2 (en) | 2015-02-10 | 2016-02-09 | Enhanced delivery of viral particles to the striatum and cortex |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021129519A Division JP2021178861A (ja) | 2015-02-10 | 2021-08-06 | 線条体および皮質へのウイルス粒子の強化された送達 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018506585A JP2018506585A (ja) | 2018-03-08 |
| JP2018506585A5 true JP2018506585A5 (https=) | 2019-03-22 |
| JP6928558B2 JP6928558B2 (ja) | 2021-09-01 |
Family
ID=56614902
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017560479A Active JP6928558B2 (ja) | 2015-02-10 | 2016-02-09 | 線条体および皮質へのウイルス粒子の強化された送達 |
| JP2021129519A Pending JP2021178861A (ja) | 2015-02-10 | 2021-08-06 | 線条体および皮質へのウイルス粒子の強化された送達 |
| JP2023018846A Pending JP2023058630A (ja) | 2015-02-10 | 2023-02-10 | 線条体および皮質へのウイルス粒子の強化された送達 |
| JP2024228114A Pending JP2025060823A (ja) | 2015-02-10 | 2024-12-25 | 線条体および皮質へのウイルス粒子の強化された送達 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021129519A Pending JP2021178861A (ja) | 2015-02-10 | 2021-08-06 | 線条体および皮質へのウイルス粒子の強化された送達 |
| JP2023018846A Pending JP2023058630A (ja) | 2015-02-10 | 2023-02-10 | 線条体および皮質へのウイルス粒子の強化された送達 |
| JP2024228114A Pending JP2025060823A (ja) | 2015-02-10 | 2024-12-25 | 線条体および皮質へのウイルス粒子の強化された送達 |
Country Status (27)
| Country | Link |
|---|---|
| US (3) | US20190111157A1 (https=) |
| EP (3) | EP4023758A1 (https=) |
| JP (4) | JP6928558B2 (https=) |
| KR (2) | KR102625784B1 (https=) |
| CN (2) | CN116019934A (https=) |
| AU (3) | AU2016219398A1 (https=) |
| BR (1) | BR112017017037A2 (https=) |
| CA (1) | CA2976082A1 (https=) |
| CL (1) | CL2017002028A1 (https=) |
| CR (1) | CR20170407A (https=) |
| DK (1) | DK3256594T3 (https=) |
| EA (1) | EA201791803A1 (https=) |
| ES (1) | ES2904504T3 (https=) |
| HU (1) | HUE057272T2 (https=) |
| IL (4) | IL313840A (https=) |
| LT (1) | LT3256594T (https=) |
| MX (2) | MX388264B (https=) |
| NZ (1) | NZ772772A (https=) |
| PH (1) | PH12017501436A1 (https=) |
| PL (1) | PL3256594T3 (https=) |
| PT (1) | PT3256594T (https=) |
| RS (1) | RS62811B1 (https=) |
| SG (3) | SG10201907399RA (https=) |
| SI (1) | SI3256594T1 (https=) |
| TN (1) | TN2017000353A1 (https=) |
| TW (1) | TWI730952B (https=) |
| WO (1) | WO2016130591A2 (https=) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015191508A1 (en) | 2014-06-09 | 2015-12-17 | Voyager Therapeutics, Inc. | Chimeric capsids |
| SG11201703148TA (en) | 2014-11-05 | 2017-05-30 | Voyager Therapeutics Inc | Aadc polynucleotides for the treatment of parkinson's disease |
| CA3193811A1 (en) | 2014-11-14 | 2016-05-19 | Voyager Therapeutics, Inc. | Compositions and methods of treating amyotrophic lateral sclerosis (als) |
| CN119876138A (zh) | 2014-11-14 | 2025-04-25 | 沃雅戈治疗公司 | 调节性多核苷酸 |
| HK1245326A1 (zh) | 2014-12-12 | 2018-08-24 | Voyager Therapeutics, Inc. | 用於生产scaav的组合物和方法 |
| TN2017000353A1 (en) * | 2015-02-10 | 2019-01-16 | Genzyme Corp | Enhanced delivery of viral particles to the striatum and cortex |
| TWI707951B (zh) | 2015-04-08 | 2020-10-21 | 美商健臻公司 | 過大腺相關載體之製造 |
| CA3019315A1 (en) | 2015-04-23 | 2016-10-27 | University Of Massachusetts | Modulation of aav vector transgene expression |
| GB201508025D0 (en) | 2015-05-11 | 2015-06-24 | Ucl Business Plc | Fabry disease gene therapy |
| RU2742352C2 (ru) | 2015-09-24 | 2021-02-05 | Байомарин Фармасьютикал Инк. | Векторы фактора fviii на основе аденоассоциированных вирусов, соответствующие вирусные частицы и содержащие их терапевтические композиции |
| EP3448987A4 (en) | 2016-04-29 | 2020-05-27 | Voyager Therapeutics, Inc. | COMPOSITIONS FOR TREATING A DISEASE |
| EP3448874A4 (en) | 2016-04-29 | 2020-04-22 | Voyager Therapeutics, Inc. | COMPOSITIONS FOR TREATING A DISEASE |
| CA3024448C (en) | 2016-05-18 | 2025-09-09 | Voyager Therapeutics, Inc. | MODULATING POLYNUCLEOTIDES |
| CA3024449A1 (en) | 2016-05-18 | 2017-11-23 | Voyager Therapeutics, Inc. | Compositions and methods of treating huntington's disease |
| WO2018044933A1 (en) | 2016-08-30 | 2018-03-08 | The Regents Of The University Of California | Methods for biomedical targeting and delivery and devices and systems for practicing the same |
| JP7059285B2 (ja) * | 2016-09-30 | 2022-04-25 | エステベ プアルマセウティカルス, エッセ.ア. | ムコ多糖症の治療のためのアデノ随伴ウイルスベクター |
| EP3613856A4 (en) * | 2017-03-31 | 2020-12-23 | Staidson(Beijing) Biopharmaceuticals Co., Ltd. | SHORT RNA EXPRESSION CASSETTE IN HAIRPIN, POLYNUCLEOTIDIAL SEQUENCE WEARING IT AND CORRESPONDING APPLICATION |
| WO2018191450A2 (en) | 2017-04-14 | 2018-10-18 | National Taiwan University Hospital | Gene therapy for aadc deficiency |
| EP3618839A4 (en) | 2017-05-05 | 2021-06-09 | Voyager Therapeutics, Inc. | COMPOSITIONS AND METHODS OF TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS (ALS) |
| JP2020518259A (ja) * | 2017-05-05 | 2020-06-25 | ボイジャー セラピューティクス インコーポレイテッドVoyager Therapeutics,Inc. | ハンチントン病治療組成物および方法 |
| JOP20190269A1 (ar) | 2017-06-15 | 2019-11-20 | Voyager Therapeutics Inc | بولي نوكليوتيدات aadc لعلاج مرض باركنسون |
| JP7229989B2 (ja) | 2017-07-17 | 2023-02-28 | ボイジャー セラピューティクス インコーポレイテッド | 軌道アレイガイドシステム |
| JP7221275B2 (ja) | 2017-08-03 | 2023-02-13 | ボイジャー セラピューティクス インコーポレイテッド | Aavを送達するための組成物および方法 |
| US20200263199A1 (en) | 2017-09-29 | 2020-08-20 | Voyager Therapeutics, Inc. | Rescue of central and peripheral neurological phenotype of friedreich's ataxia by intravenous delivery |
| TW202413649A (zh) | 2017-10-16 | 2024-04-01 | 美商航海家醫療公司 | 肌萎縮性脊髓側索硬化症(als)之治療 |
| WO2019079242A1 (en) | 2017-10-16 | 2019-04-25 | Voyager Therapeutics, Inc. | TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS (ALS) |
| BR112020020836A2 (pt) | 2018-04-13 | 2021-01-19 | University Of Massachusetts | Vetores de aav bicistrônicos codificando subunidades alfa e beta de hexosaminidase e usos dos mesmos |
| SG11202011296VA (en) | 2018-05-15 | 2020-12-30 | Voyager Therapeutics Inc | Compositions and methods for the treatment of parkinson's disease |
| CN113528510A (zh) * | 2018-06-29 | 2021-10-22 | 武汉纽福斯生物科技有限公司 | 治疗遗传性视神经病变的组合物和方法 |
| US12281321B2 (en) | 2018-09-28 | 2025-04-22 | Voyager Therapeutics, Inc. | Frataxin expression constructs having engineered promoters and methods of use thereof |
| US12448629B2 (en) | 2018-10-05 | 2025-10-21 | University Of Massachusetts | rAAV vectors for the treatment of GM1 and GM2 gangliosidosis |
| EP3880235A4 (en) * | 2018-11-14 | 2022-08-10 | REGENXBIO Inc. | GENE THERAPY OF NEURAL ZEROID LIPOFUSCINOSES |
| BR112021015817A2 (pt) * | 2019-02-22 | 2021-10-13 | The Trustees Of The University Of Pennsylvania | Vírus adeno-associado recombinante para tratamento de neurodegeneração com início na idade adulta associado a grn |
| US20220307024A1 (en) * | 2019-06-17 | 2022-09-29 | Alnylam Pharmaceuticals, Inc. | Delivery of oligonucleotides to the striatum |
| WO2021007382A1 (en) * | 2019-07-09 | 2021-01-14 | Voyager Therapeutics, Inc. | Compositions and methods for the treatment of parkinson's disease |
| US20220275367A1 (en) * | 2019-07-24 | 2022-09-01 | Voyager Therapeutics, Inc. | Compositions and methods for treating huntington's disease |
| WO2021177116A1 (ja) * | 2020-03-02 | 2021-09-10 | 国立大学法人群馬大学 | ミクログリア選択的遺伝子発現ベクター |
| JP2023517230A (ja) * | 2020-03-11 | 2023-04-24 | リモーター セラピューティクス インコーポレイテッド | 中枢神経系全体にわたってタンパク質を散在させるための方法および材料 |
| CN116171166A (zh) * | 2020-06-30 | 2023-05-26 | 塞其里斯英国有限公司 | 水包油乳液佐剂的冷过滤 |
| JP2024505885A (ja) * | 2021-01-27 | 2024-02-08 | リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル | リソソーム酸リパーゼ欠損症(lal-d)の治療のための材料及び方法 |
| US20230034817A1 (en) | 2021-04-12 | 2023-02-02 | Affinia Therapeutics Inc. | Recombinant aav for treatment of neural disease |
| WO2023113806A1 (en) | 2021-12-16 | 2023-06-22 | Affinia Therapeutics, Inc. | Recombinant aav for treatment of neural disease |
| WO2023108507A1 (en) * | 2021-12-15 | 2023-06-22 | National Institute Of Biological Sciences, Beijing | Recombinant aav vectors and use thereof |
| US20250333758A1 (en) * | 2021-12-15 | 2025-10-30 | Genans Biotechnology Co., Ltd | Microglia having car and use thereof |
| EP4499155A4 (en) * | 2022-03-25 | 2026-04-01 | Askbio Inc | METHODS AND COMPOSITIONS INTENDED FOR THE TREATMENT OF PARKINSON'S DISEASE |
| WO2024086747A1 (en) | 2022-10-19 | 2024-04-25 | Affinia Therapeutics Inc. | Recombinant aavs with improved tropism and specificity |
| WO2025151454A1 (en) * | 2024-01-08 | 2025-07-17 | AskBio Inc. | Method or system of infusing and/or predicting an infusate volume |
| WO2025227063A1 (en) | 2024-04-26 | 2025-10-30 | Affinia Therapeutics Inc. | Recombinant aavs with improved tropism and specificity |
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| US4692147A (en) | 1980-04-02 | 1987-09-08 | Medtronic, Inc. | Drug administration device |
| US5735815A (en) | 1993-07-26 | 1998-04-07 | Sentinel Medical, Inc. | Method of using fluid jet surgical cutting tool |
| AU722624B2 (en) | 1996-09-06 | 2000-08-10 | Trustees Of The University Of Pennsylvania, The | An inducible method for production of recombinant adeno-associated viruses utilizing T7 polymerase |
| US6042579A (en) | 1997-04-30 | 2000-03-28 | Medtronic, Inc. | Techniques for treating neurodegenerative disorders by infusion of nerve growth factors into the brain |
| US6995006B2 (en) | 1997-09-05 | 2006-02-07 | Targeted Genetics Corporation | Methods for generating high titer helper-free preparations of released recombinant AAV vectors |
| US6566118B1 (en) | 1997-09-05 | 2003-05-20 | Targeted Genetics Corporation | Methods for generating high titer helper-free preparations of released recombinant AAV vectors |
| DE69929600T2 (de) | 1998-05-27 | 2006-09-07 | Avigen Inc., Alameda | Konvektion-erhöhte verabreichung aadc-kodierende aav vektoren |
| PT1916258E (pt) | 1999-08-09 | 2014-07-29 | Genzyme Corp | Aumento da expressão de uma sequência nucleotídica heteróloga de cadeia simples a partir de vectores virais recombinantes por concepção da sequência de maneira que esta forme pares de bases intracadeia |
| NZ522840A (en) | 2000-06-01 | 2004-12-24 | Univ North Carolina | A parvovirus vector that carries a duplexed genome resulting in co-packaging of strands of plus and minus polarity tethered together |
| WO2003004660A1 (en) | 2001-07-03 | 2003-01-16 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Methods of administering vectors to synaptically connected neurons |
| US6723551B2 (en) | 2001-11-09 | 2004-04-20 | The United States Of America As Represented By The Department Of Health And Human Services | Production of adeno-associated virus in insect cells |
| NZ532635A (en) | 2001-11-13 | 2007-05-31 | Univ Pennsylvania | A method of identifying unknown adeno-associated virus (AAV) sequences and a kit for the method |
| GB2389791B (en) | 2002-04-30 | 2006-12-13 | Steven Gill | Implantable drug delivery pump |
| DE602004030327D1 (de) | 2003-05-21 | 2011-01-13 | Genzyme Corp | Verfahren zur herstellung von präparationen rekombinanter aav-virionen, die weitgehend frei von leeren capsiden sind |
| PT1807009E (pt) | 2004-10-05 | 2015-02-25 | Univ California | Cânula escalonada |
| US8283151B2 (en) | 2005-04-29 | 2012-10-09 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Isolation, cloning and characterization of new adeno-associated virus (AAV) serotypes |
| EP1879624B1 (en) | 2005-05-02 | 2011-09-21 | Genzyme Corporation | Gene therapy for neurometabolic disorders |
| AU2006283189B2 (en) | 2005-08-23 | 2013-01-31 | The Regents Of The University Of California | Reflux resistant cannula and system for chronic delivery of therapeutic agents using convection-enhanced delivery |
| US7588772B2 (en) | 2006-03-30 | 2009-09-15 | Board Of Trustees Of The Leland Stamford Junior University | AAV capsid library and AAV capsid proteins |
| WO2007127803A2 (en) | 2006-04-25 | 2007-11-08 | The Regents Of The University Of California | Administration of growth factors for the treatment of cns disorders |
| US20070259031A1 (en) | 2006-04-26 | 2007-11-08 | The Regents Of The University Of California | Compositions and methods for convection enhanced delivery of high molecular weight neurotherapeutics |
| WO2008144585A1 (en) | 2007-05-17 | 2008-11-27 | Medgenesis Therapeutix Inc. | Convection-enhanced delivery catheter with removable stiffening member and method for using same |
| BRPI1007155A2 (pt) | 2009-01-29 | 2017-05-30 | Univ Of California San Francisco | métodos para tratar um distúrbio neurológico cortical, e para dispensar um agente terapêutico para o córtex em um primata |
| HUE028341T2 (en) | 2009-06-16 | 2016-12-28 | Genzyme Corp | Improved methods for purification of recombinant aav vectors |
| US8663624B2 (en) | 2010-10-06 | 2014-03-04 | The Regents Of The University Of California | Adeno-associated virus virions with variant capsid and methods of use thereof |
| ES2739804T3 (es) * | 2011-02-12 | 2020-02-04 | Univ Iowa Res Found | Compuestos terapéuticos |
| DK2675902T3 (da) | 2011-02-17 | 2019-06-03 | Univ Pennsylvania | Sammensætninger og fremgangsmåder til at ændre vævsspecificitet og forbedre aav9-medieret genoverførsel |
| IL248102B (en) * | 2014-05-02 | 2022-07-01 | Genzyme Corp | aav vectors for gene therapy of the central nervous system and retina |
| TN2017000353A1 (en) * | 2015-02-10 | 2019-01-16 | Genzyme Corp | Enhanced delivery of viral particles to the striatum and cortex |
| CN111417231A (zh) | 2019-01-04 | 2020-07-14 | 青岛海尔股份有限公司 | 电磁波发生系统及具有该电磁波发生系统的加热装置 |
-
2016
- 2016-02-09 TN TNP/2017/000353A patent/TN2017000353A1/en unknown
- 2016-02-09 US US15/549,962 patent/US20190111157A1/en not_active Abandoned
- 2016-02-09 IL IL313840A patent/IL313840A/en unknown
- 2016-02-09 MX MX2017010370A patent/MX388264B/es unknown
- 2016-02-09 RS RS20220044A patent/RS62811B1/sr unknown
- 2016-02-09 EA EA201791803A patent/EA201791803A1/ru unknown
- 2016-02-09 CR CR20170407A patent/CR20170407A/es unknown
- 2016-02-09 ES ES16714066T patent/ES2904504T3/es active Active
- 2016-02-09 SG SG10201907399RA patent/SG10201907399RA/en unknown
- 2016-02-09 HU HUE16714066A patent/HUE057272T2/hu unknown
- 2016-02-09 KR KR1020177025285A patent/KR102625784B1/ko active Active
- 2016-02-09 SG SG11201706445SA patent/SG11201706445SA/en unknown
- 2016-02-09 SI SI201631446T patent/SI3256594T1/sl unknown
- 2016-02-09 AU AU2016219398A patent/AU2016219398A1/en not_active Abandoned
- 2016-02-09 IL IL296466A patent/IL296466B2/en unknown
- 2016-02-09 PT PT167140664T patent/PT3256594T/pt unknown
- 2016-02-09 PL PL16714066T patent/PL3256594T3/pl unknown
- 2016-02-09 BR BR112017017037A patent/BR112017017037A2/pt not_active Application Discontinuation
- 2016-02-09 EP EP21198081.8A patent/EP4023758A1/en not_active Withdrawn
- 2016-02-09 EP EP16714066.4A patent/EP3256594B1/en active Active
- 2016-02-09 CN CN202210805297.3A patent/CN116019934A/zh active Pending
- 2016-02-09 CN CN201680020700.4A patent/CN107530447A/zh active Pending
- 2016-02-09 EP EP23150591.8A patent/EP4219728A3/en active Pending
- 2016-02-09 DK DK16714066.4T patent/DK3256594T3/da active
- 2016-02-09 NZ NZ772772A patent/NZ772772A/en unknown
- 2016-02-09 KR KR1020247000976A patent/KR102863734B1/ko active Active
- 2016-02-09 JP JP2017560479A patent/JP6928558B2/ja active Active
- 2016-02-09 CA CA2976082A patent/CA2976082A1/en active Pending
- 2016-02-09 LT LTEPPCT/US2016/017210T patent/LT3256594T/lt unknown
- 2016-02-09 WO PCT/US2016/017210 patent/WO2016130591A2/en not_active Ceased
- 2016-02-10 SG SG10201912926VA patent/SG10201912926VA/en unknown
- 2016-02-15 TW TW105104342A patent/TWI730952B/zh active
-
2017
- 2017-08-08 CL CL2017002028A patent/CL2017002028A1/es unknown
- 2017-08-08 IL IL253894A patent/IL253894B/en unknown
- 2017-08-10 PH PH12017501436A patent/PH12017501436A1/en unknown
- 2017-08-10 MX MX2021004294A patent/MX2021004294A/es unknown
-
2021
- 2021-07-22 IL IL285060A patent/IL285060B2/en unknown
- 2021-08-06 JP JP2021129519A patent/JP2021178861A/ja active Pending
-
2022
- 2022-06-28 AU AU2022204583A patent/AU2022204583A1/en not_active Abandoned
- 2022-07-29 US US17/816,139 patent/US12465657B2/en active Active
-
2023
- 2023-02-10 JP JP2023018846A patent/JP2023058630A/ja active Pending
-
2024
- 2024-12-25 JP JP2024228114A patent/JP2025060823A/ja active Pending
-
2025
- 2025-02-26 AU AU2025201381A patent/AU2025201381A1/en active Pending
- 2025-08-01 US US19/288,561 patent/US20260048149A1/en active Pending
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