JP2018196379A5 - - Google Patents
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- JP2018196379A5 JP2018196379A5 JP2018121829A JP2018121829A JP2018196379A5 JP 2018196379 A5 JP2018196379 A5 JP 2018196379A5 JP 2018121829 A JP2018121829 A JP 2018121829A JP 2018121829 A JP2018121829 A JP 2018121829A JP 2018196379 A5 JP2018196379 A5 JP 2018196379A5
- Authority
- JP
- Japan
- Prior art keywords
- mutation
- primer
- amplification
- amplification reaction
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 230000003321 amplification Effects 0.000 claims 25
- 238000003199 nucleic acid amplification method Methods 0.000 claims 25
- 230000035772 mutation Effects 0.000 claims 20
- 238000000034 method Methods 0.000 claims 14
- 239000002773 nucleotide Substances 0.000 claims 8
- 125000003729 nucleotide group Chemical group 0.000 claims 8
- 108020004707 nucleic acids Proteins 0.000 claims 6
- 150000007523 nucleic acids Chemical class 0.000 claims 6
- 102000039446 nucleic acids Human genes 0.000 claims 6
- 108091034117 Oligonucleotide Proteins 0.000 claims 5
- 108091093037 Peptide nucleic acid Proteins 0.000 claims 5
- 108020004999 messenger RNA Proteins 0.000 claims 4
- 108020004705 Codon Proteins 0.000 claims 2
- 238000009396 hybridization Methods 0.000 claims 2
- 239000002299 complementary DNA Substances 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 238000010839 reverse transcription Methods 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261652827P | 2012-05-29 | 2012-05-29 | |
| US61/652,827 | 2012-05-29 | ||
| US13/840,142 US10077474B2 (en) | 2012-05-29 | 2013-03-15 | Method of designing primers, method of detecting single nucleotide polymorphisms (SNPs), method of distinguishing SNPs, and related primers, detectable oligonucleotides, and kits |
| US13/840,142 | 2013-03-15 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015515106A Division JP6448534B2 (ja) | 2012-05-29 | 2013-05-28 | ヒトbrafのコドン600における一塩基多型(snp)を検出する方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018196379A JP2018196379A (ja) | 2018-12-13 |
| JP2018196379A5 true JP2018196379A5 (OSRAM) | 2019-02-14 |
Family
ID=49670689
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015515106A Expired - Fee Related JP6448534B2 (ja) | 2012-05-29 | 2013-05-28 | ヒトbrafのコドン600における一塩基多型(snp)を検出する方法 |
| JP2018121829A Pending JP2018196379A (ja) | 2012-05-29 | 2018-06-27 | ヒトbrafのコドン600における一塩基多型(snp)を検出する方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015515106A Expired - Fee Related JP6448534B2 (ja) | 2012-05-29 | 2013-05-28 | ヒトbrafのコドン600における一塩基多型(snp)を検出する方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10077474B2 (OSRAM) |
| EP (2) | EP3604552A1 (OSRAM) |
| JP (2) | JP6448534B2 (OSRAM) |
| AU (2) | AU2013267660B2 (OSRAM) |
| CA (1) | CA2875281A1 (OSRAM) |
| ES (1) | ES2751371T3 (OSRAM) |
| WO (1) | WO2013181125A2 (OSRAM) |
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| US11322224B2 (en) | 2010-05-18 | 2022-05-03 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US12152275B2 (en) | 2010-05-18 | 2024-11-26 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US12221653B2 (en) | 2010-05-18 | 2025-02-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11939634B2 (en) | 2010-05-18 | 2024-03-26 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US20190010543A1 (en) | 2010-05-18 | 2019-01-10 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| JP6153874B2 (ja) | 2011-02-09 | 2017-06-28 | ナテラ, インコーポレイテッド | 非侵襲的出生前倍数性呼び出しのための方法 |
| US10385396B2 (en) | 2012-04-19 | 2019-08-20 | The Medical College Of Wisconsin, Inc. | Highly sensitive surveillance using detection of cell free DNA |
| US20140100126A1 (en) | 2012-08-17 | 2014-04-10 | Natera, Inc. | Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data |
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| US12492429B2 (en) | 2014-04-21 | 2025-12-09 | Natera, Inc. | Detecting mutations and ploidy in chromosomal segments |
| JP6659575B2 (ja) | 2014-04-21 | 2020-03-04 | ナテラ, インコーポレイテッド | 変異の検出および染色体分節の倍数性 |
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| CN109477138A (zh) | 2016-04-15 | 2019-03-15 | 纳特拉公司 | 肺癌检测方法 |
| CA3022545A1 (en) * | 2016-04-29 | 2017-11-02 | The Medical College Of Wisconsin, Inc. | Multiplexed optimized mismatch amplification (moma)-real time pcr for assessing cancer |
| CN105861689A (zh) * | 2016-05-06 | 2016-08-17 | 北京晋祺生物科技有限公司 | 一种cyp3a5*3的检测引物组合物、试剂盒及方法 |
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| EP3642354B1 (en) | 2017-06-20 | 2022-08-03 | Bio-Rad Laboratories, Inc. | Digital amplification assays for genetic instability |
| EP3642353B1 (en) | 2017-06-20 | 2025-03-05 | The Medical College of Wisconsin, Inc. | Assessing transplant complication risk with total cell-free dna |
| WO2019099420A1 (en) * | 2017-11-15 | 2019-05-23 | Yan Wang | A method for detecting multiple dna mutations and copy number variations |
| US12084720B2 (en) | 2017-12-14 | 2024-09-10 | Natera, Inc. | Assessing graft suitability for transplantation |
| CN112236535A (zh) | 2018-04-14 | 2021-01-15 | 纳特拉公司 | 用于借助于循环肿瘤dna的个人化检测的癌症检测和监测的方法 |
| US12234509B2 (en) | 2018-07-03 | 2025-02-25 | Natera, Inc. | Methods for detection of donor-derived cell-free DNA |
| CN113490749A (zh) * | 2018-12-31 | 2021-10-08 | 雅培分子公司 | 改进的核酸扩增 |
| WO2020145734A1 (ko) * | 2019-01-11 | 2020-07-16 | 주식회사 진캐스트 | Braf 돌연변이 검출을 위한 dna 중합효소 및 이를 포함하는 키트 |
| US11931674B2 (en) | 2019-04-04 | 2024-03-19 | Natera, Inc. | Materials and methods for processing blood samples |
| IL291819A (en) * | 2019-10-02 | 2022-06-01 | Univ Rutgers | Assay methods and kits for detecting rare sequence variants |
| EP4143336A4 (en) * | 2020-04-28 | 2024-07-24 | Cepheid | PSEUDOCOMPLEMENTARY BASES IN GENOTYPING AND NUCLEIC ACID SEQUENCING |
| WO2023013421A1 (ja) * | 2021-08-03 | 2023-02-09 | 国立大学法人群馬大学 | 腫瘍マーカーca19-9によるがん診断の精度向上を目的とする血液型関連糖鎖遺伝子の迅速スクリーニングのための新規手法 |
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-
2013
- 2013-03-15 US US13/840,142 patent/US10077474B2/en not_active Expired - Fee Related
- 2013-05-28 EP EP19187147.4A patent/EP3604552A1/en not_active Withdrawn
- 2013-05-28 CA CA2875281A patent/CA2875281A1/en not_active Abandoned
- 2013-05-28 EP EP13798093.4A patent/EP2855708B1/en active Active
- 2013-05-28 AU AU2013267660A patent/AU2013267660B2/en not_active Ceased
- 2013-05-28 WO PCT/US2013/042817 patent/WO2013181125A2/en not_active Ceased
- 2013-05-28 JP JP2015515106A patent/JP6448534B2/ja not_active Expired - Fee Related
- 2013-05-28 ES ES13798093T patent/ES2751371T3/es active Active
-
2018
- 2018-06-27 JP JP2018121829A patent/JP2018196379A/ja active Pending
- 2018-08-20 US US16/105,057 patent/US20190032133A1/en not_active Abandoned
- 2018-10-19 AU AU2018250508A patent/AU2018250508A1/en not_active Abandoned
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