JP2018135352A5 - - Google Patents

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JP2018135352A5
JP2018135352A5 JP2018073109A JP2018073109A JP2018135352A5 JP 2018135352 A5 JP2018135352 A5 JP 2018135352A5 JP 2018073109 A JP2018073109 A JP 2018073109A JP 2018073109 A JP2018073109 A JP 2018073109A JP 2018135352 A5 JP2018135352 A5 JP 2018135352A5
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Japan
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JP2018073109A
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Japanese (ja)
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JP6810717B2 (ja
JP2018135352A (ja
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Publication of JP2018135352A5 publication Critical patent/JP2018135352A5/ja
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JP2018073109A 2012-08-01 2018-04-05 プロスタサイクリン処理された内皮前駆細胞による肺動脈性高血圧症の処置 Active JP6810717B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261678208P 2012-08-01 2012-08-01
US61/678,208 2012-08-01
US201361750458P 2013-01-09 2013-01-09
US61/750,458 2013-01-09

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2015525509A Division JP6746313B2 (ja) 2012-08-01 2013-07-30 プロスタサイクリン処理された内皮前駆細胞による肺動脈性高血圧症の処置

Publications (3)

Publication Number Publication Date
JP2018135352A JP2018135352A (ja) 2018-08-30
JP2018135352A5 true JP2018135352A5 (enExample) 2018-10-11
JP6810717B2 JP6810717B2 (ja) 2021-01-06

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ID=50028652

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2015525509A Active JP6746313B2 (ja) 2012-08-01 2013-07-30 プロスタサイクリン処理された内皮前駆細胞による肺動脈性高血圧症の処置
JP2018073109A Active JP6810717B2 (ja) 2012-08-01 2018-04-05 プロスタサイクリン処理された内皮前駆細胞による肺動脈性高血圧症の処置

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2015525509A Active JP6746313B2 (ja) 2012-08-01 2013-07-30 プロスタサイクリン処理された内皮前駆細胞による肺動脈性高血圧症の処置

Country Status (9)

Country Link
US (4) US10016463B2 (enExample)
EP (2) EP2879684B1 (enExample)
JP (2) JP6746313B2 (enExample)
KR (1) KR102143961B1 (enExample)
CN (1) CN104936603A (enExample)
CA (1) CA2880811C (enExample)
ES (2) ES2713988T3 (enExample)
IN (1) IN2015DN00976A (enExample)
WO (1) WO2014022376A2 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2713988T3 (es) * 2012-08-01 2019-05-24 United Therapeutics Corp Tratamiento de hipertensión arterial pulmonar con células progenitoras endoteliales tratadas con prostaciclina
EP2879682B1 (en) 2012-08-01 2018-03-21 United Therapeutics Corporation Treatment of pulmonary arterial hypertension with mesenchymal stem cells
ES2963968T3 (es) * 2013-01-09 2024-04-03 United Therapeutics Corp Tratamiento de la vasculopatía con prostaciclina y células madre mesenquimatosas
PL3060041T3 (pl) 2013-10-25 2021-08-02 Insmed Incorporated Związki prostacykliny
US20170049822A1 (en) * 2014-04-23 2017-02-23 Texas Heart Institute Methods of enhancing stem cell engraftment
ES2873873T3 (es) 2014-11-18 2021-11-04 Insmed Inc Métodos de fabricación de treprostinilo y profármacos derivados de treprostinilo
US10344023B2 (en) 2014-12-23 2019-07-09 Proteostasis Therapeutics, Inc. Derivatives of 3-heteroarylisoxazol-5-carboxylic amide useful for the treatment of inter alia cystic fibrosis
BR112018070747B1 (pt) 2016-04-07 2024-01-09 Proteostasis Therapeutics, Inc Átomos de silicone contendo análogos de ivacaftor, composições farmacêuticas e usos terapêuticos
EP3534917B1 (en) * 2016-10-24 2022-08-24 United Therapeutics Corporation Enhancement of msc immunomodulatory properties by treprostinil
KR20190109399A (ko) * 2016-12-05 2019-09-25 코세어 파마 인코포레이티드 트레프로스티닐 및 이의 염의 피부 및 경피 투여
MX2021003866A (es) 2018-10-05 2021-09-08 Xenotherapeutics Inc Productos y metodos de xenotransplante.
US10883084B2 (en) 2018-10-05 2021-01-05 Xenotherapeutics, Inc. Personalized cells, tissues, and organs for transplantation from a humanized, bespoke, designated-pathogen free, (non-human) donor and methods and products relating to same
JP7455144B2 (ja) 2019-04-29 2024-03-25 インスメッド インコーポレイテッド トレプロスチニルプロドラッグの乾燥粉末組成物およびその使用方法
WO2021011550A1 (en) * 2019-07-15 2021-01-21 Yale University Methods and compositions for treating pulmonary arterial hypertension
KR20220054359A (ko) * 2019-08-28 2022-05-02 아스텔라스 인스티튜트 포 리제너러티브 메디슨 혈관 질병을 치료하는 방법

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3089815A (en) 1951-10-11 1963-05-14 Lieb Hans Injectable pharmaceutical preparation, and a method of making same
US4352883A (en) 1979-03-28 1982-10-05 Damon Corporation Encapsulation of biological material
US4353888A (en) 1980-12-23 1982-10-12 Sefton Michael V Encapsulation of live animal cells
US4714680B1 (en) 1984-02-06 1995-06-27 Univ Johns Hopkins Human stem cells
US4965204A (en) 1984-02-06 1990-10-23 The Johns Hopkins University Human stem cells and monoclonal antibodies
US5130144B1 (en) 1984-02-06 1995-08-15 Univ Johns Hopkins Human stem cells and monoclonal antibodies
US5026365A (en) 1987-04-29 1991-06-25 The University Of Massachusetts Method and apparatus for therapeutically treating immunological disorders and disease states
US4983393A (en) 1987-07-21 1991-01-08 Maximed Corporation Intra-vaginal device and method for sustained drug release
ES2035317T5 (es) 1987-11-09 1998-03-16 Becton Dickinson Co Metodo para analizar celulas hematopoyeticas en una muestra.
US5283187A (en) 1987-11-17 1994-02-01 Brown University Research Foundation Cell culture-containing tubular capsule produced by co-extrusion
US5158881A (en) 1987-11-17 1992-10-27 Brown University Research Foundation Method and system for encapsulating cells in a tubular extrudate in separate cell compartments
US5071741A (en) 1988-04-18 1991-12-10 Cryolife, Inc. Cryoprotective agent and its use in cryopreservation of cellular matter
DE3829752A1 (de) 1988-09-01 1990-03-22 Akzo Gmbh Integrale asymmetrische polyaethersulfonmembran, verfahren zur herstellung und verwendung zur ultrafiltration und mikrofiltration
DE3829766A1 (de) 1988-09-01 1990-03-22 Akzo Gmbh Verfahren zur herstellung von membranen
US5084350A (en) 1990-02-16 1992-01-28 The Royal Institution For The Advance Of Learning (Mcgill University) Method for encapsulating biologically active material including cells
US5061620A (en) 1990-03-30 1991-10-29 Systemix, Inc. Human hematopoietic stem cell
US5283058A (en) 1990-08-30 1994-02-01 The General Hospital Corporation Methods for inhibiting rejection of transplanted tissue
US5173414A (en) 1990-10-30 1992-12-22 Applied Immune Sciences, Inc. Production of recombinant adeno-associated virus vectors
US5811094A (en) 1990-11-16 1998-09-22 Osiris Therapeutics, Inc. Connective tissue regeneration using human mesenchymal stem cell preparations
HK1001832A1 (en) 1991-04-25 1998-07-10 Brown University Research Foundation Implantable biocompatible immunoisolatory vehicle for delivery of selected therapeutic products
CA2128527A1 (en) 1992-01-21 1993-07-22 Raymond P. Goodrich, Jr. Method of freezing cells and cell-like materials
US5834256A (en) 1993-06-11 1998-11-10 Cell Genesys, Inc. Method for production of high titer virus and high efficiency retroviral mediated transduction of mammalian cells
JP4098355B2 (ja) 1993-08-12 2008-06-11 ニューロテック ユーエスエー, インコーポレイテッド 遺伝的に改変された細胞を含む生体適合性免疫隔離カプセル
US5518878A (en) 1993-09-15 1996-05-21 Organogenesis Inc. Cryopreservation of cultured skin or cornea equivalents with agitation
US5693531A (en) 1993-11-24 1997-12-02 The United States Of America As Represented By The Department Of Health And Human Services Vector systems for the generation of adeno-associated virus particles
EP0748215B1 (en) 1994-02-17 2003-05-28 New York Blood Center, Inc. Biologic bioadhesive compositions containing fibrin glue and liposomes, methods of preparation and use
US7252989B1 (en) 1994-04-04 2007-08-07 Board Of Regents, The University Of Texas System Adenovirus supervector system
US5580714A (en) 1995-03-08 1996-12-03 Celox Laboratories, Inc. Cryopreservation solution
US5629145A (en) 1995-03-24 1997-05-13 Organ, Inc. Cryopreservation of cell suspensions
US5643192A (en) 1995-04-06 1997-07-01 Hamilton Civic Hospitals Research Development, Inc. Autologous fibrin glue and methods for its preparation and use
US5910434A (en) 1995-12-15 1999-06-08 Systemix, Inc. Method for obtaining retroviral packaging cell lines producing high transducing efficiency retroviral supernatant
WO1997021824A2 (en) 1995-12-15 1997-06-19 Systemix, Inc. Method for obtaining retroviral vector supernatant having high transduction efficiency
AU4659697A (en) 1996-10-03 1998-04-24 Regents Of The University Of California, The Cryopreservation of human adult and fetal pancreatic cells and human platelets
ATE307195T1 (de) 1997-07-14 2005-11-15 Osiris Therapeutics Inc Herzmuskelregenerierung unter verwendung mesenchymaler stammzellen
US20030118567A1 (en) * 1999-03-26 2003-06-26 Stewart Duncan John Cell-based therapy for the pulmonary system
US9585916B2 (en) 1999-03-26 2017-03-07 Northern Therapeutics Inc. Cell based therapy for the pulmonary system
US6197294B1 (en) 1998-10-26 2001-03-06 Neurotech S.A. Cell surface molecule-induced macrophage activation
AU2003901668A0 (en) 2003-03-28 2003-05-01 Medvet Science Pty. Ltd. Non-haemopoietic precursor cells
AUPQ147799A0 (en) 1999-07-07 1999-07-29 Medvet Science Pty. Ltd. Mesenchymal precursor cell
US9320829B2 (en) * 2000-03-15 2016-04-26 Orbusneich Medical, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
AU7362301A (en) 2000-06-22 2002-01-02 Sam L Austin Bioadhesive compositions and methods of preparation and use
WO2004050180A2 (en) 2002-11-30 2004-06-17 Cardiac Pacemakers, Inc. Method and apparatus for cell and electrical therapy of living tissue
DE602004028155D1 (de) 2003-12-16 2010-08-26 United Therapeutics Corp Verwendung von treprostinil zur behandlung von ischämischen läsionen
CN101506355B (zh) 2004-09-24 2012-06-27 成血管细胞系统公司 多能扩增间充质前体细胞子代(memp)及其应用
EP2548569B1 (en) 2005-08-19 2014-01-29 Duke University Stem cell derived paracrine factor h1 for use in reducing cell death in cardiac tissue
US20070065414A1 (en) 2005-09-16 2007-03-22 Boston Scientific Scimed, Inc. Enhanced delivery of cells
US8652201B2 (en) * 2006-04-26 2014-02-18 The Cleveland Clinic Foundation Apparatus and method for treating cardiovascular diseases
WO2007124594A1 (en) 2006-04-27 2007-11-08 Cell Therapy Technologies, Inc. Et Al. Stem cells for treating lung diseases
WO2008077094A2 (en) 2006-12-19 2008-06-26 Children's Medical Center Corporation Methods for promoting neovascularization
SI2120977T1 (sl) 2007-02-12 2014-01-31 Anthrogenesis Coroporation Zdravljenje vnetnih bolezni z uporabo placentarnih matičnih celic
JP2011015609A (ja) * 2007-10-30 2011-01-27 Asahikawa Medical College 内皮前駆細胞(epc)の増殖・分化誘導方法
AU2009215934C1 (en) 2008-02-22 2014-05-08 Agency For Science, Technology And Research (A*Star) Mesenchymal stem cell particles
EP2608797B1 (en) 2010-08-27 2015-09-23 University of Miami Bone marrow derived cd271 precursor cells for cardiac repair
EP3269802B1 (en) 2011-09-30 2019-10-23 Bluebird Bio, Inc. Compounds for improved viral transduction
EP2879682B1 (en) 2012-08-01 2018-03-21 United Therapeutics Corporation Treatment of pulmonary arterial hypertension with mesenchymal stem cells
ES2713988T3 (es) * 2012-08-01 2019-05-24 United Therapeutics Corp Tratamiento de hipertensión arterial pulmonar con células progenitoras endoteliales tratadas con prostaciclina
ES2963968T3 (es) 2013-01-09 2024-04-03 United Therapeutics Corp Tratamiento de la vasculopatía con prostaciclina y células madre mesenquimatosas
US9924630B2 (en) 2014-11-14 2018-03-27 Luitauras Kairys Device for connecting two rakes
EP3534917B1 (en) 2016-10-24 2022-08-24 United Therapeutics Corporation Enhancement of msc immunomodulatory properties by treprostinil

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