JP2018135352A5 - - Google Patents

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Publication number
JP2018135352A5
JP2018135352A5 JP2018073109A JP2018073109A JP2018135352A5 JP 2018135352 A5 JP2018135352 A5 JP 2018135352A5 JP 2018073109 A JP2018073109 A JP 2018073109A JP 2018073109 A JP2018073109 A JP 2018073109A JP 2018135352 A5 JP2018135352 A5 JP 2018135352A5
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JP
Japan
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JP2018073109A
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Japanese (ja)
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JP2018135352A (ja
JP6810717B2 (ja
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Publication of JP2018135352A5 publication Critical patent/JP2018135352A5/ja
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JP2018073109A 2012-08-01 2018-04-05 プロスタサイクリン処理された内皮前駆細胞による肺動脈性高血圧症の処置 Active JP6810717B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261678208P 2012-08-01 2012-08-01
US61/678,208 2012-08-01
US201361750458P 2013-01-09 2013-01-09
US61/750,458 2013-01-09

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2015525509A Division JP6746313B2 (ja) 2012-08-01 2013-07-30 プロスタサイクリン処理された内皮前駆細胞による肺動脈性高血圧症の処置

Publications (3)

Publication Number Publication Date
JP2018135352A JP2018135352A (ja) 2018-08-30
JP2018135352A5 true JP2018135352A5 (enExample) 2018-10-11
JP6810717B2 JP6810717B2 (ja) 2021-01-06

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ID=50028652

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2015525509A Active JP6746313B2 (ja) 2012-08-01 2013-07-30 プロスタサイクリン処理された内皮前駆細胞による肺動脈性高血圧症の処置
JP2018073109A Active JP6810717B2 (ja) 2012-08-01 2018-04-05 プロスタサイクリン処理された内皮前駆細胞による肺動脈性高血圧症の処置

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2015525509A Active JP6746313B2 (ja) 2012-08-01 2013-07-30 プロスタサイクリン処理された内皮前駆細胞による肺動脈性高血圧症の処置

Country Status (9)

Country Link
US (4) US10016463B2 (enExample)
EP (2) EP3492084B1 (enExample)
JP (2) JP6746313B2 (enExample)
KR (1) KR102143961B1 (enExample)
CN (1) CN104936603A (enExample)
CA (1) CA2880811C (enExample)
ES (2) ES2869701T3 (enExample)
IN (1) IN2015DN00976A (enExample)
WO (1) WO2014022376A2 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104936603A (zh) * 2012-08-01 2015-09-23 联合治疗公司 利用前列环素处理的内皮祖细胞的肺动脉高血压的治疗
IN2015DN00934A (enExample) 2012-08-01 2015-06-12 United Therapeutics Corp
WO2014110094A1 (en) * 2013-01-09 2014-07-17 United Therapeutics Corporation Treatment of vasculopathy with prostacyclin and mesenchymal stem cells
MX382833B (es) 2013-10-25 2025-03-13 Insmed Inc Compuestos derivados de prostaciclinas, y el uso de los mismo para el tratamiento de la hipertension pulmonar
WO2015164506A1 (en) * 2014-04-23 2015-10-29 Texas Heart Institute Methods of enhancing stem cell engraftment
EP3221291B1 (en) 2014-11-18 2021-03-31 Insmed Incorporated Methods of manufacturing treprostinil and treprostinil derivative prodrugs
CA2971835A1 (en) 2014-12-23 2016-06-30 Proteostasis Therapeutics, Inc. Derivatives of 3-heteroarylisoxazol-5-carboxylic amide useful for the treatment of inter alia cystic fibrosis
US10662207B2 (en) 2016-04-07 2020-05-26 Proteostasis Therapeutics, Inc. Compounds, compositions, and methods for modulating CFTR
IL266175B2 (en) * 2016-10-24 2024-01-01 United Therapeutics Corp Enhancement of msc immunomodulatory properties by treprostinil
US20190290597A1 (en) * 2016-12-05 2019-09-26 Corsair Pharma, Inc. Dermal and transdermal administration of treprostinil and salts thereof
US10883084B2 (en) 2018-10-05 2021-01-05 Xenotherapeutics, Inc. Personalized cells, tissues, and organs for transplantation from a humanized, bespoke, designated-pathogen free, (non-human) donor and methods and products relating to same
IL281867B2 (en) 2018-10-05 2024-07-01 Xenotherapeutics Inc Xenotransplantation products and methods
BR112021021775A2 (pt) 2019-04-29 2022-01-04 Insmed Inc Composições de pó seco de pró-fármacos de treprostinil e métodos de uso destas
EP3999030A4 (en) * 2019-07-15 2023-08-16 Yale University Methods and compositions for treating pulmonary arterial hypertension
EP4022042A1 (en) * 2019-08-28 2022-07-06 Astellas Institute for Regenerative Medicine Methods of treating vascular diseases

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3089815A (en) 1951-10-11 1963-05-14 Lieb Hans Injectable pharmaceutical preparation, and a method of making same
US4352883A (en) 1979-03-28 1982-10-05 Damon Corporation Encapsulation of biological material
US4353888A (en) 1980-12-23 1982-10-12 Sefton Michael V Encapsulation of live animal cells
US4965204A (en) 1984-02-06 1990-10-23 The Johns Hopkins University Human stem cells and monoclonal antibodies
US4714680B1 (en) 1984-02-06 1995-06-27 Univ Johns Hopkins Human stem cells
US5130144B1 (en) 1984-02-06 1995-08-15 Univ Johns Hopkins Human stem cells and monoclonal antibodies
US5026365A (en) 1987-04-29 1991-06-25 The University Of Massachusetts Method and apparatus for therapeutically treating immunological disorders and disease states
US4983393A (en) 1987-07-21 1991-01-08 Maximed Corporation Intra-vaginal device and method for sustained drug release
ATE81724T1 (de) 1987-11-09 1992-11-15 Becton Dickinson Co Verfahren zur analyse haematopoietischer zellen in einer probe.
US5283187A (en) 1987-11-17 1994-02-01 Brown University Research Foundation Cell culture-containing tubular capsule produced by co-extrusion
US5158881A (en) 1987-11-17 1992-10-27 Brown University Research Foundation Method and system for encapsulating cells in a tubular extrudate in separate cell compartments
US5071741A (en) 1988-04-18 1991-12-10 Cryolife, Inc. Cryoprotective agent and its use in cryopreservation of cellular matter
DE3829752A1 (de) 1988-09-01 1990-03-22 Akzo Gmbh Integrale asymmetrische polyaethersulfonmembran, verfahren zur herstellung und verwendung zur ultrafiltration und mikrofiltration
DE3829766A1 (de) 1988-09-01 1990-03-22 Akzo Gmbh Verfahren zur herstellung von membranen
US5084350A (en) 1990-02-16 1992-01-28 The Royal Institution For The Advance Of Learning (Mcgill University) Method for encapsulating biologically active material including cells
US5061620A (en) 1990-03-30 1991-10-29 Systemix, Inc. Human hematopoietic stem cell
US5283058A (en) 1990-08-30 1994-02-01 The General Hospital Corporation Methods for inhibiting rejection of transplanted tissue
US5173414A (en) 1990-10-30 1992-12-22 Applied Immune Sciences, Inc. Production of recombinant adeno-associated virus vectors
US5811094A (en) 1990-11-16 1998-09-22 Osiris Therapeutics, Inc. Connective tissue regeneration using human mesenchymal stem cell preparations
WO1992019195A1 (en) 1991-04-25 1992-11-12 Brown University Research Foundation Implantable biocompatible immunoisolatory vehicle for delivery of selected therapeutic products
AU672775B2 (en) 1992-01-21 1996-10-17 Cobe Laboratories Inc. Method of freezing cells and cell-like materials
US5834256A (en) 1993-06-11 1998-11-10 Cell Genesys, Inc. Method for production of high titer virus and high efficiency retroviral mediated transduction of mammalian cells
ATE218893T1 (de) 1993-08-12 2002-06-15 Neurotech Sa Biokompatible immunoisolatorische kapseln, die genetisch veränderte zellen enthalten
US5518878A (en) 1993-09-15 1996-05-21 Organogenesis Inc. Cryopreservation of cultured skin or cornea equivalents with agitation
US5693531A (en) 1993-11-24 1997-12-02 The United States Of America As Represented By The Department Of Health And Human Services Vector systems for the generation of adeno-associated virus particles
WO1995022316A1 (en) 1994-02-17 1995-08-24 New York Blood Center, Inc. Biologic bioadhesive compositions containing fibrin glue and liposomes, methods of preparation and use
US7252989B1 (en) 1994-04-04 2007-08-07 Board Of Regents, The University Of Texas System Adenovirus supervector system
US5580714A (en) 1995-03-08 1996-12-03 Celox Laboratories, Inc. Cryopreservation solution
US5629145A (en) 1995-03-24 1997-05-13 Organ, Inc. Cryopreservation of cell suspensions
US5643192A (en) 1995-04-06 1997-07-01 Hamilton Civic Hospitals Research Development, Inc. Autologous fibrin glue and methods for its preparation and use
JP2000501614A (ja) 1995-12-15 2000-02-15 システミックス,インコーポレイテッド 高形質導入効率を有するレトロウイルスベクター上清を得るための方法
US5910434A (en) 1995-12-15 1999-06-08 Systemix, Inc. Method for obtaining retroviral packaging cell lines producing high transducing efficiency retroviral supernatant
AU4659697A (en) 1996-10-03 1998-04-24 Regents Of The University Of California, The Cryopreservation of human adult and fetal pancreatic cells and human platelets
CA2296704C (en) 1997-07-14 2010-10-19 Osiris Therapeutics, Inc. Cardiac muscle regeneration using mesenchymal stem cells
US20030118567A1 (en) 1999-03-26 2003-06-26 Stewart Duncan John Cell-based therapy for the pulmonary system
US9585916B2 (en) * 1999-03-26 2017-03-07 Northern Therapeutics Inc. Cell based therapy for the pulmonary system
US6197294B1 (en) 1998-10-26 2001-03-06 Neurotech S.A. Cell surface molecule-induced macrophage activation
AU2003901668A0 (en) 2003-03-28 2003-05-01 Medvet Science Pty. Ltd. Non-haemopoietic precursor cells
AUPQ147799A0 (en) 1999-07-07 1999-07-29 Medvet Science Pty. Ltd. Mesenchymal precursor cell
US9320829B2 (en) * 2000-03-15 2016-04-26 Orbusneich Medical, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
WO2001097872A1 (en) 2000-06-22 2001-12-27 Austin Sam L Bioadhesive compositions and methods of preparation and use
JP2006511312A (ja) 2002-11-30 2006-04-06 カーディアック・ペースメーカーズ・インコーポレーテッド 生体組織の細胞治療と電気治療の方法と装置
ES2347254T3 (es) 2003-12-16 2010-10-27 United Therapeutics Corporation Utilizacion de treprostinil para el tratamiento de las lesiones isquemicas.
WO2006032092A1 (en) 2004-09-24 2006-03-30 Angioblast Systems, Inc. Multipotential expanded mesenchymal precursor cell progeny (memp) and uses thereof
EP2226079B1 (en) 2005-08-19 2012-07-11 Duke University Stem cell derived paracrine factor SFRP2 for use in reducing cell death associated with myocardial infarction
US20070065414A1 (en) 2005-09-16 2007-03-22 Boston Scientific Scimed, Inc. Enhanced delivery of cells
US8652201B2 (en) * 2006-04-26 2014-02-18 The Cleveland Clinic Foundation Apparatus and method for treating cardiovascular diseases
US20090274665A1 (en) 2006-04-27 2009-11-05 Cell Therapy Technologies, Inc. Stem Cells For Treating Lung Diseases
US20100040584A1 (en) 2006-12-19 2010-02-18 Children's Medical Center Corporation Methods for promoting neovascularization
EP2687220A3 (en) 2007-02-12 2014-05-14 Anthrogenesis Corporation Treatment of inflammatory diseases using placental stem cells
JP2011015609A (ja) * 2007-10-30 2011-01-27 Asahikawa Medical College 内皮前駆細胞(epc)の増殖・分化誘導方法
HUE026536T2 (en) 2008-02-22 2016-06-28 Agency For Science Tech And Res (A Star) Mesenchymal stem cell particles
US20140023621A1 (en) 2010-08-27 2014-01-23 University Of Miami Bone marrow derived cd271 precursor cells for cardiac repair
PT2760994T (pt) 2011-09-30 2017-08-24 Bluebird Bio Inc Compostos para melhor transdução viral
IN2015DN00934A (enExample) 2012-08-01 2015-06-12 United Therapeutics Corp
CN104936603A (zh) * 2012-08-01 2015-09-23 联合治疗公司 利用前列环素处理的内皮祖细胞的肺动脉高血压的治疗
WO2014110094A1 (en) * 2013-01-09 2014-07-17 United Therapeutics Corporation Treatment of vasculopathy with prostacyclin and mesenchymal stem cells
US9924630B2 (en) 2014-11-14 2018-03-27 Luitauras Kairys Device for connecting two rakes
IL266175B2 (en) 2016-10-24 2024-01-01 United Therapeutics Corp Enhancement of msc immunomodulatory properties by treprostinil

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