JP2020040981A5 - - Google Patents

Download PDF

Info

Publication number
JP2020040981A5
JP2020040981A5 JP2019211952A JP2019211952A JP2020040981A5 JP 2020040981 A5 JP2020040981 A5 JP 2020040981A5 JP 2019211952 A JP2019211952 A JP 2019211952A JP 2019211952 A JP2019211952 A JP 2019211952A JP 2020040981 A5 JP2020040981 A5 JP 2020040981A5
Authority
JP
Japan
Prior art keywords
invention described
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2019211952A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020040981A (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2020040981A publication Critical patent/JP2020040981A/ja
Publication of JP2020040981A5 publication Critical patent/JP2020040981A5/ja
Pending legal-status Critical Current

Links

JP2019211952A 2011-02-18 2019-11-25 ミエリン形成細胞運命へのオリゴデンドロサイト前駆細胞の定方向分化 Pending JP2020040981A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161444666P 2011-02-18 2011-02-18
US61/444,666 2011-02-18

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2017026806A Division JP2017132769A (ja) 2011-02-18 2017-02-16 ミエリン形成細胞運命へのオリゴデンドロサイト前駆細胞の定方向分化

Publications (2)

Publication Number Publication Date
JP2020040981A JP2020040981A (ja) 2020-03-19
JP2020040981A5 true JP2020040981A5 (enExample) 2020-08-20

Family

ID=46672968

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2013554652A Expired - Fee Related JP6133790B2 (ja) 2011-02-18 2012-02-17 ミエリン形成細胞運命へのオリゴデンドロサイト前駆細胞の定方向分化
JP2017026806A Pending JP2017132769A (ja) 2011-02-18 2017-02-16 ミエリン形成細胞運命へのオリゴデンドロサイト前駆細胞の定方向分化
JP2019211952A Pending JP2020040981A (ja) 2011-02-18 2019-11-25 ミエリン形成細胞運命へのオリゴデンドロサイト前駆細胞の定方向分化

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP2013554652A Expired - Fee Related JP6133790B2 (ja) 2011-02-18 2012-02-17 ミエリン形成細胞運命へのオリゴデンドロサイト前駆細胞の定方向分化
JP2017026806A Pending JP2017132769A (ja) 2011-02-18 2017-02-16 ミエリン形成細胞運命へのオリゴデンドロサイト前駆細胞の定方向分化

Country Status (6)

Country Link
US (4) US9592288B2 (enExample)
EP (2) EP2675893B1 (enExample)
JP (3) JP6133790B2 (enExample)
DK (1) DK2675893T3 (enExample)
ES (1) ES2716865T3 (enExample)
WO (1) WO2012112933A1 (enExample)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2675893T3 (en) 2011-02-18 2019-04-15 Scripps Research Inst Directed differentiation of oligodendrocyte precursor cells into a myelinating cell fate
AU2012293276B2 (en) * 2011-08-07 2016-07-14 Kadimastem Ltd. Method of identifying agents that affect maturation, survival and myelination
EP2724723A1 (en) * 2012-10-25 2014-04-30 Universitätsklinikum Hamburg-Eppendorf Tegaserod for use in the treatment of nerve injuries
BR112015016189A8 (pt) * 2013-01-08 2019-10-22 Pathologica Llc usos de metilglioxal bis (guanilhidrazona) (“mgbg”), uso de metilglioxal bis (guanilhidrazona) (“mgbg”) e um agente e composição farmacêutica
US10905663B2 (en) 2013-03-05 2021-02-02 The University Of Chicago Treatment of demyelinating disorders
CN112521305B (zh) * 2013-03-15 2023-04-25 苏州泰飞尔医药有限公司 治疗帕金森疾病的新型高穿透力药物及其药物组合物
WO2015023675A2 (en) 2013-08-12 2015-02-19 Pharmaceutical Manufacturing Research Services, Inc. Extruded immediate release abuse deterrent pill
GB201317363D0 (en) 2013-10-01 2013-11-13 Eisai Ltd Novel compounds
US9492444B2 (en) 2013-12-17 2016-11-15 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
US10172797B2 (en) 2013-12-17 2019-01-08 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
EP3082845B1 (en) * 2013-12-20 2021-02-17 University Of Manitoba Methods and compositions for treatment of peripheral neuropathies
AU2015290098B2 (en) 2014-07-17 2018-11-01 Pharmaceutical Manufacturing Research Services, Inc. Immediate release abuse deterrent liquid fill dosage form
AU2015336065A1 (en) 2014-10-20 2017-05-04 Pharmaceutical Manufacturing Research Services, Inc. Extended release abuse deterrent liquid fill dosage form
FR3029113A1 (fr) * 2014-12-02 2016-06-03 Univ Paris-Sud Composes pour le traitement des maladies mitochondriales
EP3118621A1 (en) * 2015-07-14 2017-01-18 Fundació Institut d'Investigació Biomèdica de Bellvitge (IDIBELL) Methods and compositions for the diagnosis and for the treatment of adrenoleukodystrophy
JP6898310B2 (ja) * 2015-09-02 2021-07-07 トレベナ・インコーポレイテッドＴｒｅｖｅｎａ， Ｉｎｃ． ６員アザヘテロ環を含有するデルタ−オピオイド受容体調節化合物、同化合物を使用する方法、および同化合物を作る方法
CN107286031B (zh) * 2016-04-05 2019-08-09 上海医药工业研究院 2-二乙氨基-1-甲基乙基-7-环己基-7-氧庚酸酯的制备方法
AU2017357072A1 (en) * 2016-11-14 2019-05-30 Memorial Sloan-Kettering Cancer Center Stem cell derived schwann cells
AU2018221705B2 (en) 2017-02-17 2022-10-27 Trevena, Inc. 7-membered aza-heterocyclic containing delta-opioid receptor modulating compounds, methods of using and making the same
US11702408B2 (en) 2017-02-17 2023-07-18 Trevena, Inc. 5-membered aza-heterocyclic containing delta-opioid receptor modulating compounds, methods of using and making the same
CA3059578A1 (en) * 2017-04-13 2018-10-18 The Board Of Trustees Of The Leland Stanford Junior University Personalized 3d neural culture system for generating human oligodendrocytes and studying myelination in vitro
US11478467B2 (en) * 2017-05-04 2022-10-25 Sreenivasarao Vepachedu Targeted drug rescue with novel compositions, combinations, and methods thereof
EP3412294A1 (en) 2017-06-08 2018-12-12 Universite De Fribourg Hdac1/2 activator for promoting and/or accelerating myelination and/or remyelination
HUE069820T2 (hu) 2018-03-08 2025-04-28 Victoria Link Ltd Nalfurafin alkalmazása demielinizációs betegségek kezelésére
AU2018411573A1 (en) * 2018-03-08 2020-10-01 The Scripps Research Institute Methods for promoting myelination and for treating demyelinating diseases
WO2019195742A1 (en) * 2018-04-05 2019-10-10 Frequency Therapeutics, Inc. Compositions and methods for increasing remyelination
AU2019253059A1 (en) * 2018-04-13 2020-11-12 Mordechai Chevion Compositions and methods for treatment of demyelination
CN108624560B (zh) * 2018-06-01 2022-04-08 南京艾尔普再生医学科技有限公司 一种分化培养基及少突胶质前体细胞的制备方法
WO2019241744A1 (en) * 2018-06-14 2019-12-19 Curasen Therapeutics, Inc. Methods for diagnosing, monitoring and treating neurological diseases and disorders
EP3863628B1 (en) * 2018-10-09 2023-12-27 MediciNova, Inc. Combination of ibudilast and interferon-beta and methods of using same
CN111317754B (zh) * 2018-12-13 2022-02-18 泰州医药城国科化物生物医药科技有限公司 一种北豆根总碱的制备方法及应用
CN109942592B (zh) * 2019-05-09 2020-07-14 江西中医药大学 一种新原阿片碱型生物碱及其制备方法和应用
EP3797769A1 (fr) * 2019-09-25 2021-03-31 Fontès, M. Michel Composition a usage therapeutique
US11752149B2 (en) 2019-12-02 2023-09-12 Pipeline Therapeutics, Inc. Muscarinic acetylcholine M1 receptor antagonists
US20230346746A1 (en) * 2020-01-22 2023-11-02 Technophage, Investigaçäo E Desenvolvimento Em Biotecnologia, S.A. Eletriptan hydrobromide for treatment of spinal cord injury and improvement of locomotor function
US20230167406A1 (en) * 2020-05-01 2023-06-01 The Children's Medical Center Corporation Compositions and methods of promoting myelination
EP4342471A4 (en) * 2021-05-21 2025-05-28 Chengdu Wending Technology Development Co., Ltd. METHOD FOR MODULATING NEUROPATHIES
WO2023171736A1 (ja) 2022-03-11 2023-09-14 帝人ファーマ株式会社 免疫調節性物質と組み合わせて使用される、ビタミンｄ誘導体またはその医薬上許容される塩もしくは溶媒和物を含有する医薬
WO2023225206A1 (en) 2022-05-18 2023-11-23 The Scripps Research Institute Method for enhancing remyelination via co-administration of muscarinic receptor antagonists and vitamin d analogues
CN116115760A (zh) * 2022-12-15 2023-05-16 浙江大学 Eed抑制剂在制备治疗神经免疫性疾病药物中的应用
WO2025049588A1 (en) * 2023-08-29 2025-03-06 The Trustees Of Indiana University Novel treatments for optic neuropathies and glaucoma
CN117599054B (zh) * 2024-01-24 2024-03-29 成都第一制药有限公司 一种治疗假性近视的药物组合物及其用途

Family Cites Families (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4933438A (en) 1984-02-29 1990-06-12 University Of Florida Brain-specific analogues of centrally acting amines
US5506337A (en) 1985-03-15 1996-04-09 Antivirals Inc. Morpholino-subunit combinatorial library and method
US6150354A (en) 1987-01-15 2000-11-21 Bonnie Davis Compounds for the treatment of Alzheimer's disease
US5010175A (en) 1988-05-02 1991-04-23 The Regents Of The University Of California General method for producing and selecting peptides with specific properties
US5133974A (en) 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
IE66205B1 (en) 1990-06-14 1995-12-13 Paul A Bartlett Polypeptide analogs
US5650489A (en) 1990-07-02 1997-07-22 The Arizona Board Of Regents Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
DK0584185T3 (da) 1991-05-14 2000-02-07 Ernir Snorrason Behandling af træthedssyndrom med cholinesteraseinhibitorer
IT1250421B (it) 1991-05-30 1995-04-07 Recordati Chem Pharm Composizione farmaceutica a rilascio controllato con proprieta' bio-adesive.
US5573905A (en) 1992-03-30 1996-11-12 The Scripps Research Institute Encoded combinatorial chemical libraries
US5264459A (en) * 1992-07-13 1993-11-23 Arch Development Corporation Use of β-adrenergic agonists to treat patients with demyelinating or autoimmune diseases
US5288514A (en) 1992-09-14 1994-02-22 The Regents Of The University Of California Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support
US6537579B1 (en) 1993-02-22 2003-03-25 American Bioscience, Inc. Compositions and methods for administration of pharmacologically active compounds
FR2710265B1 (fr) 1993-09-22 1995-10-20 Adir Composition pharmaceutique bioadhésive pour la libération contrôlée de principes actifs.
US5519134A (en) 1994-01-11 1996-05-21 Isis Pharmaceuticals, Inc. Pyrrolidine-containing monomers and oligomers
US5593853A (en) 1994-02-09 1997-01-14 Martek Corporation Generation and screening of synthetic drug libraries
US5539083A (en) 1994-02-23 1996-07-23 Isis Pharmaceuticals, Inc. Peptide nucleic acid combinatorial libraries and improved methods of synthesis
US5525735A (en) 1994-06-22 1996-06-11 Affymax Technologies Nv Methods for synthesizing diverse collections of pyrrolidine compounds
US5549974A (en) 1994-06-23 1996-08-27 Affymax Technologies Nv Methods for the solid phase synthesis of thiazolidinones, metathiazanones, and derivatives thereof
US6548084B2 (en) 1995-07-20 2003-04-15 Smithkline Beecham Plc Controlled release compositions
US6245347B1 (en) 1995-07-28 2001-06-12 Zars, Inc. Methods and apparatus for improved administration of pharmaceutically active compounds
US5569588A (en) 1995-08-09 1996-10-29 The Regents Of The University Of California Methods for drug screening
DE19541260A1 (de) 1995-11-06 1997-05-07 Lohmann Therapie Syst Lts Therapeutische Zubereitung zur transdermalen Applikation von Wirkstoffen durch die Haut
US6512010B1 (en) 1996-07-15 2003-01-28 Alza Corporation Formulations for the administration of fluoxetine
JPH10218867A (ja) 1997-02-10 1998-08-18 Pola Chem Ind Inc ドーパミン再取り込み阻害剤
JP2001515854A (ja) 1997-09-11 2001-09-25 ニュコメデ ダンマルク アクティーゼルスカブ 非ステロイド性抗炎症薬物質（ＮＳＡＩＤｓ）の改良された開放性多重−単位組成物
US6624200B2 (en) 1998-08-25 2003-09-23 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
US6607751B1 (en) 1997-10-10 2003-08-19 Intellipharamaceutics Corp. Controlled release delivery device for pharmaceutical agents incorporating microbial polysaccharide gum
US6403597B1 (en) 1997-10-28 2002-06-11 Vivus, Inc. Administration of phosphodiesterase inhibitors for the treatment of premature ejaculation
US6248864B1 (en) 1997-12-31 2001-06-19 Adherex Technologies, Inc. Compounds and methods and modulating tissue permeability
US6613358B2 (en) 1998-03-18 2003-09-02 Theodore W. Randolph Sustained-release composition including amorphous polymer
WO2000001376A2 (en) * 1998-07-02 2000-01-13 Eisai Co., Ltd Pharmaceutical compositions and their uses for treatment of demyelinating disorders
US6312717B1 (en) 1998-07-07 2001-11-06 Bristol-Myers Squibb Company Method for treatment of anxiety and depression
US20020009478A1 (en) 1998-08-24 2002-01-24 Douglas Joseph Dobrozsi Oral liquid mucoadhesive compositions
SE9802864D0 (sv) 1998-08-27 1998-08-27 Pharmacia & Upjohn Ab Transdermally administered tolterodine as antimuscarinic agent for the treatment of overactive bladder
TR200100931T2 (tr) 1998-10-01 2001-10-22 Novartis Ag Yeni sürekli salınımlı oral formülasyonlar
US6248363B1 (en) 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
FR2792527B1 (fr) 1999-04-22 2004-08-13 Ethypharm Lab Prod Ethiques Microgranules de ketoprofene, procede de preparation et compositions pharmaceutiques
US6541020B1 (en) 1999-07-09 2003-04-01 Trimeris, Inc. Methods and compositions for administration of therapeutic reagents
US6562375B1 (en) 1999-08-04 2003-05-13 Yamanouchi Pharmaceuticals, Co., Ltd. Stable pharmaceutical composition for oral use
PT1207860E (pt) 1999-09-02 2008-01-24 Nostrum Pharmaceuticals Inc Formulação de peletes de libertação controlada
US6544548B1 (en) 1999-09-13 2003-04-08 Keraplast Technologies, Ltd. Keratin-based powders and hydrogel for pharmaceutical applications
US6080736A (en) 1999-10-27 2000-06-27 Janus Pharmaceuticals, Inc. Methods and compositions for treating and preventing anxiety and anxiety disorders using optically pure (R) tofisopam
US6461631B1 (en) 1999-11-16 2002-10-08 Atrix Laboratories, Inc. Biodegradable polymer composition
AU2463701A (en) 1999-12-29 2001-07-09 Nanodelivery, Inc. Drug delivery system exhibiting permeability control
US6589549B2 (en) 2000-04-27 2003-07-08 Macromed, Incorporated Bioactive agent delivering system comprised of microparticles within a biodegradable to improve release profiles
US6524621B2 (en) 2000-05-01 2003-02-25 Aeropharm Technology Inc. Core formulation
IL153565A0 (en) 2000-06-20 2003-07-06 Atherogenics Inc 1,3-bis-(substituted-phenyl)-2-propen-1-ones and their use to treat vcam-1 mediated disorders
US6482440B2 (en) 2000-09-21 2002-11-19 Phase 2 Discovery, Inc. Long acting antidepressant microparticles
EP1360296B1 (en) * 2001-02-07 2006-11-29 National Research Council Of Canada Method for the production of plant seed with modified fibre content and modified seed coat
US6524615B2 (en) 2001-02-21 2003-02-25 Kos Pharmaceuticals, Incorporated Controlled release pharmaceutical composition
CA2475767A1 (en) 2002-02-07 2003-08-14 The Curators Of The University Of Missouri Opioid receptor active 4-(3-hydroxyphenyl) or 4-(3-alkoxyphenyl)-1,2,4-triazole compounds
US7304071B2 (en) 2002-08-14 2007-12-04 Vertex Pharmaceuticals Incorporated Protein kinase inhibitors and uses thereof
CA2518854A1 (en) * 2003-03-21 2004-10-07 Wyeth Treating immunological disorder using agonists of interleukin-21/interleukin-21 receptor
JP2007530703A (ja) * 2004-04-01 2007-11-01 アベンティス・ファーマスーティカルズ・インコーポレイテツド Ｍｓおよびその他の脱髄疾患を治療するためのペルオキシソーム増殖因子活性化受容体デルタアゴニストの使用
DK1797109T3 (en) * 2004-09-09 2016-04-11 Yeda Res & Dev MIXTURES OF POLYPEPTIDES, compositions containing them and methods for their preparation, and uses thereof
GB0424564D0 (en) 2004-11-05 2004-12-08 Novartis Ag Organic compounds
WO2008063849A2 (en) * 2006-11-03 2008-05-29 Northwestern University Multiple sclerosis therapy
US20080286234A1 (en) 2007-05-15 2008-11-20 Eyink Daniel A Method for treating demyelinating diseases
EP2173344B1 (en) * 2007-06-29 2016-04-06 Clarencew Pty Ltd. Treatment or prophylaxis or neurological or neuropsychiatric disorders via ocular administration
WO2009012569A1 (en) 2007-07-20 2009-01-29 Stem Cell Therapeutics Corp. TREATING OR AMELIORATING A NEUROMFLAMMATORY OR DEMYELIMATING DISORDER WITH PROLACTIN AND INTERFERON-β
WO2009073146A2 (en) 2007-11-29 2009-06-11 Celgene Corporation Use of immunomodulatory compounds for the treatment of transverse myelitis, multiple sclerosis, and other disorders
EP2065038A1 (en) 2007-11-30 2009-06-03 Pharnext New therapeutic approaches for treating Charcot-Marie-Tooth disease
EP2135607A1 (en) 2008-06-18 2009-12-23 Pharnext Combination of pilocarpin and methimazol for treating Charcot-MarieTooth disease and related disorders
SG171404A1 (en) 2008-12-22 2011-07-28 Novartis Ag Dosage regimen for a s1p receptor agonist
SG10201406168RA (en) * 2009-09-29 2014-11-27 Novartis Ag Dosage regimen of an s1p receptor modulator
DK2675893T3 (en) 2011-02-18 2019-04-15 Scripps Research Inst Directed differentiation of oligodendrocyte precursor cells into a myelinating cell fate

Similar Documents

Publication Publication Date Title
JP2020040981A5 (enExample)
JP2020007340A5 (enExample)
JP2021151238A5 (enExample)
JP2023085489A5 (enExample)
JP2023105131A5 (enExample)
JP2020534795A5 (enExample)
JP2021048879A5 (enExample)
JP2020042034A5 (enExample)
JP2020530297A5 (enExample)
JP2023052878A5 (enExample)
JP2019030304A5 (enExample)
JP2019099571A5 (enExample)
JP2021502066A5 (enExample)
JP2017214405A5 (enExample)
JP2019068846A5 (enExample)
JP2020010717A5 (enExample)
JP2021100406A5 (enExample)
JP2021038271A5 (enExample)
JP2021500894A5 (enExample)
JP2018154848A5 (enExample)
JP2019142968A5 (enExample)
JP2019031552A5 (enExample)
JPWO2020148954A5 (enExample)
JP2018135352A5 (enExample)
JP2018111825A5 (enExample)