JP2018048151A5 - - Google Patents

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Publication number
JP2018048151A5
JP2018048151A5 JP2017192907A JP2017192907A JP2018048151A5 JP 2018048151 A5 JP2018048151 A5 JP 2018048151A5 JP 2017192907 A JP2017192907 A JP 2017192907A JP 2017192907 A JP2017192907 A JP 2017192907A JP 2018048151 A5 JP2018048151 A5 JP 2018048151A5
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JP
Japan
Prior art keywords
inhibitor
cancer stem
brain tumor
pharmaceutical composition
stem cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2017192907A
Other languages
English (en)
Japanese (ja)
Other versions
JP2018048151A (ja
JP6618968B2 (ja
Filing date
Publication date
Priority claimed from EP10185930A external-priority patent/EP2446895A1/en
Application filed filed Critical
Publication of JP2018048151A publication Critical patent/JP2018048151A/ja
Publication of JP2018048151A5 publication Critical patent/JP2018048151A5/ja
Application granted granted Critical
Publication of JP6618968B2 publication Critical patent/JP6618968B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2017192907A 2010-10-01 2017-10-02 腫瘍幹細胞におけるeph受容体発現 Active JP6618968B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10185930.4 2010-10-01
EP10185930A EP2446895A1 (en) 2010-10-01 2010-10-01 EPH receptor expression in tumor stem cells

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2015200808A Division JP6523910B2 (ja) 2010-10-01 2015-10-09 腫瘍幹細胞におけるeph受容体発現

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019205190A Division JP2020037579A (ja) 2010-10-01 2019-11-13 腫瘍幹細胞におけるeph受容体発現

Publications (3)

Publication Number Publication Date
JP2018048151A JP2018048151A (ja) 2018-03-29
JP2018048151A5 true JP2018048151A5 (enExample) 2018-05-17
JP6618968B2 JP6618968B2 (ja) 2019-12-11

Family

ID=43856109

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2013530753A Pending JP2013540117A (ja) 2010-10-01 2011-09-30 腫瘍幹細胞におけるeph受容体発現
JP2015200808A Active JP6523910B2 (ja) 2010-10-01 2015-10-09 腫瘍幹細胞におけるeph受容体発現
JP2017192907A Active JP6618968B2 (ja) 2010-10-01 2017-10-02 腫瘍幹細胞におけるeph受容体発現
JP2019205190A Pending JP2020037579A (ja) 2010-10-01 2019-11-13 腫瘍幹細胞におけるeph受容体発現

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP2013530753A Pending JP2013540117A (ja) 2010-10-01 2011-09-30 腫瘍幹細胞におけるeph受容体発現
JP2015200808A Active JP6523910B2 (ja) 2010-10-01 2015-10-09 腫瘍幹細胞におけるeph受容体発現

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2019205190A Pending JP2020037579A (ja) 2010-10-01 2019-11-13 腫瘍幹細胞におけるeph受容体発現

Country Status (11)

Country Link
US (1) US9078857B2 (enExample)
EP (2) EP2446895A1 (enExample)
JP (4) JP2013540117A (enExample)
KR (2) KR20130095286A (enExample)
AU (1) AU2011310109B2 (enExample)
CA (1) CA2813101C (enExample)
DK (1) DK2621513T3 (enExample)
ES (1) ES2616444T3 (enExample)
NZ (1) NZ609594A (enExample)
PL (1) PL2621513T3 (enExample)
WO (1) WO2012042021A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ611428A (en) 2010-12-08 2015-07-31 Stemcentrx Inc Novel modulators and methods of use
SA112330278B1 (ar) 2011-02-18 2015-10-09 ستيم سينتركس، انك. مواد ضابطة جديدة وطرق للاستخدام
EP2733206A1 (en) * 2012-11-19 2014-05-21 Naroa LLC Method for the isolation for mammalian stem cells using EphA2 and uses thereof
JP2016540826A (ja) 2013-11-04 2016-12-28 ファイザー・インク 抗efna4抗体−薬物コンジュゲート
RU2708075C2 (ru) 2014-04-30 2019-12-04 Пфайзер Инк. Конъюгаты анти-ртк7 антитело-лекарственное средство
WO2016092378A1 (en) * 2014-12-10 2016-06-16 Angelo Luigi Vescovi Methods and compositions for reducing growth, migration and invasiveness of brain cancer stem cells and improving survival of patients with brian tumors
KR20180016391A (ko) 2015-05-08 2018-02-14 플로우조, 엘엘시 데이터 발견 노드
US11174484B2 (en) 2015-11-10 2021-11-16 B. G. Negev Technologies And Applications Ltd., At Ben- Gurion University Means and methods for reducing tumorigenicity of cancer stem cells
EP4129311A4 (en) * 2020-03-31 2024-06-12 Keio University Therapeutic agent using genome-edited pluripotent stem cell
WO2026022122A1 (en) * 2024-07-23 2026-01-29 Eos Research Sa Checkpoint inhibitors in the treatment of glioblastoma multiforme

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1682173A4 (en) * 2003-10-15 2007-10-31 Medimmune Inc EPHA2 VACCINE ON LISTERIA BASE
EP1778726A4 (en) * 2004-08-16 2009-03-18 Medimmune Inc INTEGRIN ANTAGONISTS WITH IMPROVED ANTIBODY-DEPENDENT CELL-ASSAYED CYTOTOXICITY ACTIVITY
US20070248628A1 (en) * 2005-12-06 2007-10-25 Keller Lorraine H Immunogens in cancer stem cells
US8343461B2 (en) * 2006-03-08 2013-01-01 Wake Forest University Health Sciences Molecular signature of cancer
BRPI0816094A2 (pt) * 2007-08-30 2015-03-03 Daiichi Sankyo Co Ltd Anticorpo, polipeptídeo, hibridoma, composição farmacêutica, método para inibir o desenvolvimento de tumor em um mamífero, polinucleotídeo, célula hospedeira, e, método para produzir um anticorpo.

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