ES2616444T3 - Expresión del receptor Eph en las células madre tumorales - Google Patents
Expresión del receptor Eph en las células madre tumorales Download PDFInfo
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- ES2616444T3 ES2616444T3 ES11778540.2T ES11778540T ES2616444T3 ES 2616444 T3 ES2616444 T3 ES 2616444T3 ES 11778540 T ES11778540 T ES 11778540T ES 2616444 T3 ES2616444 T3 ES 2616444T3
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
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- Dermatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10185930A EP2446895A1 (en) | 2010-10-01 | 2010-10-01 | EPH receptor expression in tumor stem cells |
| EP10185930 | 2010-10-01 | ||
| PCT/EP2011/067114 WO2012042021A1 (en) | 2010-10-01 | 2011-09-30 | Eph receptor expression in tumor stem cells |
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| ES2616444T3 true ES2616444T3 (es) | 2017-06-13 |
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| ES11778540.2T Active ES2616444T3 (es) | 2010-10-01 | 2011-09-30 | Expresión del receptor Eph en las células madre tumorales |
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| EP (2) | EP2446895A1 (enExample) |
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| TWI655210B (zh) | 2010-12-08 | 2019-04-01 | 艾伯維史坦森特瑞斯有限責任公司 | 新穎調節劑及其使用方法 |
| SA112330278B1 (ar) | 2011-02-18 | 2015-10-09 | ستيم سينتركس، انك. | مواد ضابطة جديدة وطرق للاستخدام |
| EP2733206A1 (en) * | 2012-11-19 | 2014-05-21 | Naroa LLC | Method for the isolation for mammalian stem cells using EphA2 and uses thereof |
| BR112016010051A2 (pt) | 2013-11-04 | 2017-12-05 | Pfizer | ?conjugados de anticorpo-fármaco anti-efna4? |
| EP3137114B8 (en) | 2014-04-30 | 2021-08-04 | Pfizer Inc. | Anti-ptk7 antibody-drug conjugates |
| EP3229831B1 (en) | 2014-12-10 | 2020-03-11 | Hyperstem SA | Methods and compositions for reducing growth, migration and invasiveness of brain cancer stem cells and improving survival of patients with brain tumors |
| JP6758368B2 (ja) * | 2015-05-08 | 2020-09-23 | フロージョー エルエルシーＦｌｏｗＪｏ， ＬＬＣ | データ発見ノード |
| EP3373939A4 (en) | 2015-11-10 | 2019-06-26 | B.G. Negev Technologies and Applications Ltd., at Ben-Gurion University | MEDIUM AND METHOD FOR REDUCING TUMORIGENITY OF CANCER STEM CELLS |
| WO2021201100A1 (ja) * | 2020-03-31 | 2021-10-07 | 学校法人 慶應義塾 | ゲノム編集多能性幹細胞を用いた治療薬 |
| WO2026022122A1 (en) * | 2024-07-23 | 2026-01-29 | Eos Research Sa | Checkpoint inhibitors in the treatment of glioblastoma multiforme |
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| US20050281783A1 (en) * | 2003-10-15 | 2005-12-22 | Kinch Michael S | Listeria-based EphA2 vaccines |
| AU2005277641A1 (en) * | 2004-08-16 | 2006-03-02 | Medimmune, Llc | Eph receptor Fc variants with enhanced antibody dependent cell-mediated cytotoxicity activity |
| US20070248628A1 (en) * | 2005-12-06 | 2007-10-25 | Keller Lorraine H | Immunogens in cancer stem cells |
| US8343461B2 (en) * | 2006-03-08 | 2013-01-01 | Wake Forest University Health Sciences | Molecular signature of cancer |
| SI2199390T1 (sl) * | 2007-08-30 | 2017-02-28 | Daiichi Sankyo Company, Limited | Proti-epha2 protitelo |
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2010
- 2010-10-01 EP EP10185930A patent/EP2446895A1/en not_active Withdrawn
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2011
- 2011-04-18 US US13/089,217 patent/US9078857B2/en active Active
- 2011-09-30 JP JP2013530753A patent/JP2013540117A/ja active Pending
- 2011-09-30 AU AU2011310109A patent/AU2011310109B2/en active Active
- 2011-09-30 DK DK11778540.2T patent/DK2621513T3/en active
- 2011-09-30 ES ES11778540.2T patent/ES2616444T3/es active Active
- 2011-09-30 KR KR1020167002577A patent/KR101719966B1/ko active Active
- 2011-09-30 NZ NZ609594A patent/NZ609594A/en unknown
- 2011-09-30 KR KR1020137011310A patent/KR20130095286A/ko not_active Ceased
- 2011-09-30 PL PL11778540T patent/PL2621513T3/pl unknown
- 2011-09-30 WO PCT/EP2011/067114 patent/WO2012042021A1/en not_active Ceased
- 2011-09-30 CA CA2813101A patent/CA2813101C/en active Active
- 2011-09-30 EP EP11778540.2A patent/EP2621513B1/en active Active
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2015
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2017
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2019
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Also Published As
| Publication number | Publication date |
|---|---|
| NZ609594A (en) | 2015-01-30 |
| WO2012042021A1 (en) | 2012-04-05 |
| US20120083454A1 (en) | 2012-04-05 |
| EP2621513A1 (en) | 2013-08-07 |
| JP2018048151A (ja) | 2018-03-29 |
| EP2446895A1 (en) | 2012-05-02 |
| DK2621513T3 (en) | 2017-03-06 |
| JP2016094391A (ja) | 2016-05-26 |
| JP2020037579A (ja) | 2020-03-12 |
| JP6523910B2 (ja) | 2019-06-05 |
| AU2011310109B2 (en) | 2014-11-20 |
| CA2813101A1 (en) | 2012-04-05 |
| KR20130095286A (ko) | 2013-08-27 |
| KR101719966B1 (ko) | 2017-03-24 |
| JP2013540117A (ja) | 2013-10-31 |
| KR20160027106A (ko) | 2016-03-09 |
| CA2813101C (en) | 2018-10-30 |
| PL2621513T3 (pl) | 2017-06-30 |
| JP6618968B2 (ja) | 2019-12-11 |
| US9078857B2 (en) | 2015-07-14 |
| AU2011310109A1 (en) | 2013-05-02 |
| EP2621513B1 (en) | 2016-12-28 |
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