JP2016501013A5 - - Google Patents
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- Publication number
- JP2016501013A5 JP2016501013A5 JP2015541144A JP2015541144A JP2016501013A5 JP 2016501013 A5 JP2016501013 A5 JP 2016501013A5 JP 2015541144 A JP2015541144 A JP 2015541144A JP 2015541144 A JP2015541144 A JP 2015541144A JP 2016501013 A5 JP2016501013 A5 JP 2016501013A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- vitro
- cell activator
- γδt
- activator
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229940126530 T cell activator Drugs 0.000 claims 9
- 238000000338 in vitro Methods 0.000 claims 8
- 210000004027 cell Anatomy 0.000 claims 7
- 238000000034 method Methods 0.000 claims 7
- 210000001744 T-lymphocyte Anatomy 0.000 claims 4
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 230000001939 inductive effect Effects 0.000 claims 2
- 230000035755 proliferation Effects 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 230000006052 T cell proliferation Effects 0.000 claims 1
- 239000012190 activator Substances 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 230000005784 autoimmunity Effects 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- YKAYCWPQDPILSA-UHFFFAOYSA-N bromohydrin pyrophosphate Chemical compound BrCC(O)(C)CCOP(O)(=O)OP(O)(O)=O YKAYCWPQDPILSA-UHFFFAOYSA-N 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 210000003819 peripheral blood mononuclear cell Anatomy 0.000 claims 1
- 230000002062 proliferating effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12306385.1 | 2012-11-08 | ||
| EP12306385 | 2012-11-08 | ||
| PCT/EP2013/073328 WO2014072446A1 (en) | 2012-11-08 | 2013-11-08 | Method for inducing il-2-free proliferation of gamma delta t cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016501013A JP2016501013A (ja) | 2016-01-18 |
| JP2016501013A5 true JP2016501013A5 (enExample) | 2016-12-28 |
Family
ID=47189860
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015541144A Pending JP2016501013A (ja) | 2012-11-08 | 2013-11-08 | γδＴ細胞の無ＩＬ−２増殖を誘導するための方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20150259645A1 (enExample) |
| EP (1) | EP2916858A1 (enExample) |
| JP (1) | JP2016501013A (enExample) |
| WO (1) | WO2014072446A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3218515B1 (en) | 2014-11-10 | 2023-04-26 | F. Hoffmann-La Roche AG | Therapeutic and diagnostic methods for il-33-mediated disorders |
| CR20170240A (es) | 2014-11-10 | 2018-04-03 | Genentech Inc | Anticuerpos anti-interleucina-33 y sus usos |
| JP7146397B2 (ja) | 2014-11-17 | 2022-10-04 | アディセット バイオ， インコーポレイテッド | 改変γδＴ細胞 |
| US20170360907A1 (en) | 2014-12-04 | 2017-12-21 | The University Of North Carolina At Chapel Hill | Compositions and methods for preventing and treating graft versus host disease |
| CN118421557A (zh) | 2016-05-12 | 2024-08-02 | 阿迪塞特治疗公司 | 选择性扩增γδT细胞群的方法及其组合物 |
| US10758591B2 (en) | 2016-07-26 | 2020-09-01 | University Of Virginia Patent Foundation | Compositions and methods for treating clostridium difficile infection |
| CN108310367A (zh) * | 2017-01-18 | 2018-07-24 | 复旦大学 | 白介素33（il-33）在制备抗乙型肝炎病毒制剂中的用途 |
| JP7486953B2 (ja) * | 2017-05-18 | 2024-05-20 | ユーエムセー・ユトレヒト・ホールディング・ベー・フェー | 細胞標的化療法のための組成物および方法 |
| KR20200098518A (ko) | 2017-11-15 | 2020-08-20 | 아디셋 바이오, 인크. | δ3 γδ T-세포 집단의 선택적 증식을 위한 방법 및 이의 조성물 |
| DE102017127984B4 (de) | 2017-11-27 | 2019-12-05 | Immatics US, Inc. | Verfahren für die Vermehrung und Aktivierung von γδ-T-Zellen |
| JP2022513328A (ja) * | 2018-09-27 | 2022-02-07 | フォスフォガム， インコーポレイテッド | 同種異系のガンマ／デルタｔ細胞の増殖および使用のための方法および組成物 |
| CN109517793B (zh) * | 2018-11-30 | 2022-05-10 | 广州长峰生物技术有限公司 | 一种NK细胞和γδT细胞共培养的建立方法 |
| BR112021010804A2 (pt) * | 2018-12-03 | 2021-11-16 | Adicet Bio Inc | Métodos para expansão seletiva in vivo de populações de células t gama delta e composições das mesmas |
| BR112022018254A2 (pt) | 2020-03-13 | 2022-10-25 | Genentech Inc | Anticorpos isolados, ácido nucleico isolado, vetor ou conjunto de vetores, célula hospedeira, métodos para produzir um anticorpo, para tratar um distúrbio e para tratar ag em um paciente, composição e uso de um anticorpo |
| WO2023081802A2 (en) * | 2021-11-04 | 2023-05-11 | Memorial Sloan Kettering Cancer Center | Il33 proteins and methods of use thereof |
| WO2023132926A2 (en) * | 2022-01-04 | 2023-07-13 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Compositions and methods for treating cancer |
| WO2023176896A1 (ja) * | 2022-03-18 | 2023-09-21 | 国立大学法人長崎大学 | 糸状菌感染症の治療薬及び糸状菌感染症の治療方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2782721B1 (fr) * | 1998-09-01 | 2000-11-03 | Inst Nat Sante Rech Med | Nouveaux composes phosphohalohydrines, procede de fabrication et applications |
| ATE441420T1 (de) * | 2002-12-02 | 2009-09-15 | Innate Pharma | Interleukin-2 und gamma delta t zellaktivator enthaltende zusammensetzungen und deren verwendungen |
| EP1720567A2 (en) * | 2004-02-10 | 2006-11-15 | Innate Pharma | Composition and method for the treatment of carcinoma |
| ITRM20070437A1 (it) * | 2007-08-10 | 2009-02-11 | Istituto Naz Per Le Malattie I | Metodo per la generazione ed espansione di cellule t gamma/delta regolatorie cellule cosi' ottenute e loro impieghi |
| JP2010004853A (ja) * | 2008-06-30 | 2010-01-14 | Japan Health Science Foundation | 制御性ｔ細胞の製造方法 |
-
2013
- 2013-11-08 EP EP13791776.1A patent/EP2916858A1/en not_active Withdrawn
- 2013-11-08 WO PCT/EP2013/073328 patent/WO2014072446A1/en not_active Ceased
- 2013-11-08 JP JP2015541144A patent/JP2016501013A/ja active Pending
- 2013-11-08 US US14/440,921 patent/US20150259645A1/en not_active Abandoned
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