JP2007526248A5 - - Google Patents
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- Publication number
- JP2007526248A5 JP2007526248A5 JP2006551541A JP2006551541A JP2007526248A5 JP 2007526248 A5 JP2007526248 A5 JP 2007526248A5 JP 2006551541 A JP2006551541 A JP 2006551541A JP 2006551541 A JP2006551541 A JP 2006551541A JP 2007526248 A5 JP2007526248 A5 JP 2007526248A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- polypeptide
- amino acid
- acid sequence
- cell proliferation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 10
- 125000003275 alpha amino acid group Chemical group 0.000 claims 8
- 229920001184 polypeptide Polymers 0.000 claims 8
- 102000004196 processed proteins & peptides Human genes 0.000 claims 8
- 108090000765 processed proteins & peptides Proteins 0.000 claims 8
- 230000008556 epithelial cell proliferation Effects 0.000 claims 7
- 230000004936 stimulating effect Effects 0.000 claims 6
- 210000001035 gastrointestinal tract Anatomy 0.000 claims 5
- 201000010099 disease Diseases 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 210000000214 mouth Anatomy 0.000 claims 3
- 238000002512 chemotherapy Methods 0.000 claims 2
- 210000003238 esophagus Anatomy 0.000 claims 2
- 210000002429 large intestine Anatomy 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 238000001959 radiotherapy Methods 0.000 claims 2
- 210000000813 small intestine Anatomy 0.000 claims 2
- 210000002784 stomach Anatomy 0.000 claims 2
- 208000022559 Inflammatory bowel disease Diseases 0.000 claims 1
- 206010028116 Mucosal inflammation Diseases 0.000 claims 1
- 201000010927 Mucositis Diseases 0.000 claims 1
- 206010049416 Short-bowel syndrome Diseases 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53960504P | 2004-01-27 | 2004-01-27 | |
| US60/539,605 | 2004-01-27 | ||
| US61924104P | 2004-10-15 | 2004-10-15 | |
| US60/619,241 | 2004-10-15 | ||
| PCT/US2005/002996 WO2005072419A2 (en) | 2004-01-27 | 2005-01-27 | Gastrointestinal proliferative factor and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007526248A JP2007526248A (ja) | 2007-09-13 |
| JP2007526248A5 true JP2007526248A5 (enExample) | 2009-03-05 |
Family
ID=34830487
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006551541A Withdrawn JP2007526248A (ja) | 2004-01-27 | 2005-01-27 | 胃腸増殖因子およびその使用方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (4) | US20050256044A1 (enExample) |
| EP (1) | EP1727560B1 (enExample) |
| JP (1) | JP2007526248A (enExample) |
| KR (1) | KR20070007289A (enExample) |
| AU (1) | AU2005208945A1 (enExample) |
| BR (1) | BRPI0507168A (enExample) |
| CA (1) | CA2554403A1 (enExample) |
| IL (1) | IL177060A0 (enExample) |
| MX (1) | MXPA06008495A (enExample) |
| NO (1) | NO20063522L (enExample) |
| RU (2) | RU2343158C2 (enExample) |
| SG (1) | SG149059A1 (enExample) |
| TW (1) | TW200536859A (enExample) |
| WO (1) | WO2005072419A2 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE466106T1 (de) * | 2003-10-10 | 2010-05-15 | Deutsches Krebsforsch | Zusammensetzungen für die diagnose und therapie von erkrankungen, die im zusammenhang mit einer anomalen expression von futrinen (r-spondinen) stehen |
| US20190330295A1 (en) * | 2005-05-04 | 2019-10-31 | Zealand Pharma A/S | Glucagon-like-peptide-2 (glp-2) analogues |
| EP1942926A4 (en) * | 2005-10-07 | 2010-06-16 | Nuvelo Inc | STEM CELL FACTOR ARTIFICIAL PROTEIN SCFA1 AND ITS USES |
| WO2008076556A2 (en) | 2006-11-15 | 2008-06-26 | Massachusetts Eye & Ear Infirmary | Generation of inner ear cells |
| WO2008088524A2 (en) * | 2006-12-28 | 2008-07-24 | Nuvelo, Inc. | Thrombospondin-domain-deficient r-spondin 1 protein as gastrointestinal tract epithelial proliferation factor |
| ES2694018T3 (es) | 2007-07-02 | 2018-12-17 | Oncomed Pharmaceuticals, Inc. | Composiciones y métodos para el tratamiento y el diagnóstico del cáncer |
| US9464275B2 (en) | 2008-08-21 | 2016-10-11 | The Board Of Trustees Of The Leland Stanford Junior University | Ex vivo culture, proliferation and expansion of intestinal epithelium |
| WO2010060088A2 (en) * | 2008-11-24 | 2010-05-27 | Massachusetts Eye & Ear Infirmary | Pathways to generate hair cells |
| US8642339B2 (en) | 2009-02-03 | 2014-02-04 | Koninklijke Nederlandse Akademie Van Wetenschappen | Culture medium for epithelial stem cells and organoids comprising the stem cells |
| US9752124B2 (en) | 2009-02-03 | 2017-09-05 | Koninklijke Nederlandse Akademie Van Wetenschappen | Culture medium for epithelial stem cells and organoids comprising the stem cells |
| EP2412800A1 (en) | 2010-07-29 | 2012-02-01 | Koninklijke Nederlandse Akademie van Wetenschappen | Liver organoid, uses thereof and culture method for obtaining them |
| IT1396935B1 (it) | 2009-11-26 | 2012-12-20 | Solartium Entpr Ltd | Uso di una combinazione per il trattamento delle mucositi indotte da radiazioni o da chemioterapici |
| RU2532323C2 (ru) * | 2011-06-20 | 2014-11-10 | Мапикс Эс.Эй.Ар.Эл. | Лекарственное средство для лечения патологического синдрома и способ лечения функциональных нарушений кишечника |
| GB201106395D0 (en) * | 2011-04-14 | 2011-06-01 | Hubrecht Inst | Compounds |
| WO2013012747A1 (en) | 2011-07-15 | 2013-01-24 | Oncomed Pharmaceuticals, Inc. | Rspo binding agents and uses thereof |
| CN104854132A (zh) | 2012-07-13 | 2015-08-19 | 昂考梅德药品有限公司 | Rspo3结合剂及其用途 |
| EP2892506B1 (en) | 2012-09-07 | 2021-11-03 | Massachusetts Eye & Ear Infirmary | Treating hearing loss with the gamma-secretase inhibitor ly411575 |
| EP2943581B1 (en) * | 2013-01-10 | 2019-08-07 | Biocon Limited | Process for expression of recombinant proteins in pichia pastoris using a fed batch model |
| WO2016022776A2 (en) | 2014-08-06 | 2016-02-11 | Massachusetts Eye And Ear Infirmary | Increasing atoh1 life to drive sensorineural hair cell differentiantion |
| WO2016044295A1 (en) | 2014-09-16 | 2016-03-24 | Oncomed Pharmaceuticals, Inc. | Treatment of fibrotic diseases |
| EP3250678A4 (en) | 2015-01-30 | 2018-08-01 | The University of North Carolina at Chapel Hill | Methods to generate gastrointestinal epithelial tissue constructs |
| WO2017096233A1 (en) | 2015-12-04 | 2017-06-08 | Massachusetts Eye And Ear Infirmary | Treatment of hearing loss by inhibition of casein kinase 1 |
| CN109219439B (zh) | 2016-01-29 | 2022-09-20 | 马萨诸塞眼科耳科诊所 | 内耳支持细胞的扩增和分化及其使用方法 |
| EP3491122A4 (en) | 2016-07-27 | 2020-04-08 | The University of North Carolina at Chapel Hill | METHOD FOR PRODUCING POLYMER SCAFFOLDINGS WITH A GRADIENT OF CROSSLINKING DENSITY |
| US11180735B2 (en) | 2016-10-28 | 2021-11-23 | The Board Of Trustees Of The Leland Stanford Junior University | Methods to preserve tumor-stromal interactions in culture and therapeutic predictive applications thereof |
| IL271245B2 (en) | 2017-06-16 | 2023-10-01 | Zealand Pharma As | Dosing regimen for administration of glucagon-like peptide analog (GLP-2) 2 |
| GB201721615D0 (en) | 2017-12-21 | 2018-02-07 | Koninklijke Nederlandse Akademie Van Wetenschappen | Immune cell organoid co-cultures |
| US12104149B2 (en) | 2018-05-15 | 2024-10-01 | The University Of North Carolina At Chapel Hill | Devices, systems and apparatuses for generating self-sustaining hypoxic conditions and gaseous and non-gaseous chemical gradients for in vitro cell culture |
| JP7451427B2 (ja) | 2018-05-25 | 2024-03-18 | ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル | 幹細胞／増殖細胞区画及び分化細胞ゾーンを有する平面腸陰窩のアレイの形成 |
| EP3880785A4 (en) | 2018-11-16 | 2022-08-24 | The University of North Carolina at Chapel Hill | In vitro cell culture mucus systems |
| US20230338466A1 (en) * | 2020-06-03 | 2023-10-26 | Children's Hospital Medical Center | Compositions and methods comprising r-spondins for treatment of tumors |
| CA3219754A1 (en) | 2021-05-21 | 2022-11-24 | Gary Beale | Microwave treatment of tissue |
| US12465781B2 (en) | 2021-06-11 | 2025-11-11 | Joon Bu Park | Negative Poisson's ratio materials for thermal and radiation therapy seeds |
| WO2023097236A1 (en) * | 2021-11-24 | 2023-06-01 | The Rockefeller University | Compositions and methods for generating immunoglobulin knock-in mice |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL115608A0 (en) * | 1994-10-13 | 1996-01-19 | Amgen Inc | Stabilized analogs of keratinocyte growth factor |
| US6824973B2 (en) * | 2000-02-03 | 2004-11-30 | Kirin Beer Kabushiki Kaisha | Method of promoting stem cell proliferation or survival by contacting a cell with a stem cell factor-like polypeptide |
| JP2003530124A (ja) * | 2000-04-05 | 2003-10-14 | 麒麟麦酒株式会社 | 新規幹細胞成長因子様ポリペプチドおよびポリヌクレオチドに関する方法および物質 |
| US7411052B2 (en) * | 2001-03-05 | 2008-08-12 | Nuvelo, Inc. | Methods and materials relating to stem cell growth factor-like polypeptides and polynucleotides |
| US20030032034A1 (en) * | 2001-03-05 | 2003-02-13 | Tang Y. Tom | Methods and materials relating to stem cell growth factor-like polypeptides and polynucleotides |
| EP1427747B1 (en) * | 2001-08-30 | 2012-04-11 | ARCA biopharma, Inc. | Methods and materials relating to stem cell growth factor-like polypeptides and polynucleotides |
| US20050130145A1 (en) * | 2001-10-03 | 2005-06-16 | Henry Yue | Secreted proteins |
| WO2003054152A2 (en) * | 2001-12-10 | 2003-07-03 | Nuvelo, Inc. | Novel nucleic acids and polypeptides |
| US7193069B2 (en) * | 2002-03-22 | 2007-03-20 | Research Association For Biotechnology | Full-length cDNA |
| WO2005110009A2 (en) | 2003-07-22 | 2005-11-24 | Immunex Corporation | COMPOSITIONS AND METHODS RELATING TO TSP-30a, b, c AND d |
| WO2005032574A1 (en) * | 2003-10-03 | 2005-04-14 | The Board Of Trustees Of The Leland Stanford Junior University | Modulation of gastrointestinal epithelium proliferation through the wnt signaling pathway |
| ATE466106T1 (de) * | 2003-10-10 | 2010-05-15 | Deutsches Krebsforsch | Zusammensetzungen für die diagnose und therapie von erkrankungen, die im zusammenhang mit einer anomalen expression von futrinen (r-spondinen) stehen |
-
2005
- 2005-01-27 SG SG200809511-9A patent/SG149059A1/en unknown
- 2005-01-27 KR KR1020067017297A patent/KR20070007289A/ko not_active Ceased
- 2005-01-27 BR BRPI0507168-2A patent/BRPI0507168A/pt not_active IP Right Cessation
- 2005-01-27 TW TW094102490A patent/TW200536859A/zh unknown
- 2005-01-27 CA CA002554403A patent/CA2554403A1/en not_active Abandoned
- 2005-01-27 AU AU2005208945A patent/AU2005208945A1/en not_active Abandoned
- 2005-01-27 US US11/046,456 patent/US20050256044A1/en not_active Abandoned
- 2005-01-27 EP EP05712439A patent/EP1727560B1/en not_active Expired - Lifetime
- 2005-01-27 JP JP2006551541A patent/JP2007526248A/ja not_active Withdrawn
- 2005-01-27 RU RU2006130791/13A patent/RU2343158C2/ru active
- 2005-01-27 US US11/046,644 patent/US20050256036A1/en not_active Abandoned
- 2005-01-27 MX MXPA06008495A patent/MXPA06008495A/es not_active Application Discontinuation
- 2005-01-27 WO PCT/US2005/002996 patent/WO2005072419A2/en not_active Ceased
-
2006
- 2006-07-25 IL IL177060A patent/IL177060A0/en unknown
- 2006-08-02 NO NO20063522A patent/NO20063522L/no not_active Application Discontinuation
-
2007
- 2007-05-24 US US11/805,883 patent/US20080300183A1/en not_active Abandoned
-
2008
- 2008-09-09 RU RU2008136324/13A patent/RU2008136324A/ru not_active Application Discontinuation
-
2009
- 2009-10-27 US US12/589,727 patent/US7951381B2/en not_active Expired - Fee Related
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