JP2007526248A5 - - Google Patents
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- Publication number
- JP2007526248A5 JP2007526248A5 JP2006551541A JP2006551541A JP2007526248A5 JP 2007526248 A5 JP2007526248 A5 JP 2007526248A5 JP 2006551541 A JP2006551541 A JP 2006551541A JP 2006551541 A JP2006551541 A JP 2006551541A JP 2007526248 A5 JP2007526248 A5 JP 2007526248A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- polypeptide
- amino acid
- acid sequence
- cell proliferation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 10
- 125000003275 alpha amino acid group Chemical group 0.000 claims 8
- 229920001184 polypeptide Polymers 0.000 claims 8
- 102000004196 processed proteins & peptides Human genes 0.000 claims 8
- 108090000765 processed proteins & peptides Proteins 0.000 claims 8
- 230000008556 epithelial cell proliferation Effects 0.000 claims 7
- 230000004936 stimulating effect Effects 0.000 claims 6
- 210000001035 gastrointestinal tract Anatomy 0.000 claims 5
- 201000010099 disease Diseases 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 210000000214 mouth Anatomy 0.000 claims 3
- 238000002512 chemotherapy Methods 0.000 claims 2
- 210000003238 esophagus Anatomy 0.000 claims 2
- 210000002429 large intestine Anatomy 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 238000001959 radiotherapy Methods 0.000 claims 2
- 210000000813 small intestine Anatomy 0.000 claims 2
- 210000002784 stomach Anatomy 0.000 claims 2
- 208000022559 Inflammatory bowel disease Diseases 0.000 claims 1
- 206010028116 Mucosal inflammation Diseases 0.000 claims 1
- 201000010927 Mucositis Diseases 0.000 claims 1
- 206010049416 Short-bowel syndrome Diseases 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53960504P | 2004-01-27 | 2004-01-27 | |
| US60/539,605 | 2004-01-27 | ||
| US61924104P | 2004-10-15 | 2004-10-15 | |
| US60/619,241 | 2004-10-15 | ||
| PCT/US2005/002996 WO2005072419A2 (en) | 2004-01-27 | 2005-01-27 | Gastrointestinal proliferative factor and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007526248A JP2007526248A (ja) | 2007-09-13 |
| JP2007526248A5 true JP2007526248A5 (enExample) | 2009-03-05 |
Family
ID=34830487
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006551541A Withdrawn JP2007526248A (ja) | 2004-01-27 | 2005-01-27 | 胃腸増殖因子およびその使用方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (4) | US20050256036A1 (enExample) |
| EP (1) | EP1727560B1 (enExample) |
| JP (1) | JP2007526248A (enExample) |
| KR (1) | KR20070007289A (enExample) |
| AU (1) | AU2005208945A1 (enExample) |
| BR (1) | BRPI0507168A (enExample) |
| CA (1) | CA2554403A1 (enExample) |
| IL (1) | IL177060A0 (enExample) |
| MX (1) | MXPA06008495A (enExample) |
| NO (1) | NO20063522L (enExample) |
| RU (2) | RU2343158C2 (enExample) |
| SG (1) | SG149059A1 (enExample) |
| TW (1) | TW200536859A (enExample) |
| WO (1) | WO2005072419A2 (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1673475B1 (en) * | 2003-10-10 | 2010-04-28 | Deutsches Krebsforschungszentrum | Compositions for diagnosis and therapy of diseases associated with aberrant expression of futrins (r-spondins) and/or wnt |
| US20190330295A1 (en) * | 2005-05-04 | 2019-10-31 | Zealand Pharma A/S | Glucagon-like-peptide-2 (glp-2) analogues |
| EP1942926A4 (en) * | 2005-10-07 | 2010-06-16 | Nuvelo Inc | STEM CELL FACTOR ARTIFICIAL PROTEIN SCFA1 AND ITS USES |
| EP2094836B1 (en) | 2006-11-15 | 2016-06-08 | Massachusetts Eye & Ear Infirmary | Generation of inner ear cells |
| WO2008088524A2 (en) * | 2006-12-28 | 2008-07-24 | Nuvelo, Inc. | Thrombospondin-domain-deficient r-spondin 1 protein as gastrointestinal tract epithelial proliferation factor |
| EP3009148B1 (en) | 2007-07-02 | 2018-08-22 | Oncomed Pharmaceuticals, Inc. | Compositions and methods for treating and diagnosing cancer |
| US9464275B2 (en) | 2008-08-21 | 2016-10-11 | The Board Of Trustees Of The Leland Stanford Junior University | Ex vivo culture, proliferation and expansion of intestinal epithelium |
| CA2743436C (en) * | 2008-11-24 | 2017-10-31 | Massachusetts Eye & Ear Infirmary | Pathways to generate hair cells |
| PL3441458T3 (pl) | 2009-02-03 | 2023-11-06 | Koninklijke Nederlandse Akademie Van Wetenschappen | Podłoże do hodowli nabłonkowych komórek macierzystych i organoidów zawierających wspomniane komórki macierzyste |
| US9752124B2 (en) | 2009-02-03 | 2017-09-05 | Koninklijke Nederlandse Akademie Van Wetenschappen | Culture medium for epithelial stem cells and organoids comprising the stem cells |
| EP2412800A1 (en) | 2010-07-29 | 2012-02-01 | Koninklijke Nederlandse Akademie van Wetenschappen | Liver organoid, uses thereof and culture method for obtaining them |
| IT1396935B1 (it) | 2009-11-26 | 2012-12-20 | Solartium Entpr Ltd | Uso di una combinazione per il trattamento delle mucositi indotte da radiazioni o da chemioterapici |
| RU2532323C2 (ru) * | 2011-06-20 | 2014-11-10 | Мапикс Эс.Эй.Ар.Эл. | Лекарственное средство для лечения патологического синдрома и способ лечения функциональных нарушений кишечника |
| GB201106395D0 (en) * | 2011-04-14 | 2011-06-01 | Hubrecht Inst | Compounds |
| EP3401329A1 (en) | 2011-07-15 | 2018-11-14 | OncoMed Pharmaceuticals, Inc. | Rspo binding agents and uses thereof |
| JP6335896B2 (ja) | 2012-07-13 | 2018-05-30 | オンコメッド ファーマシューティカルズ インコーポレイテッド | Ｒｓｐｏ３結合剤およびその使用法 |
| HK1211875A1 (en) | 2012-09-07 | 2016-06-03 | Massachusetts Eye & Ear Infirmary | Treating hearing loss |
| US10047134B2 (en) * | 2013-01-10 | 2018-08-14 | Biocon Limited | Process for expression of recombinant proteins in Pichia pastoris using a fed batch model |
| WO2016022776A2 (en) | 2014-08-06 | 2016-02-11 | Massachusetts Eye And Ear Infirmary | Increasing atoh1 life to drive sensorineural hair cell differentiantion |
| CA2961374A1 (en) | 2014-09-16 | 2016-03-24 | Oncomed Pharmaceuticals, Inc. | Treatment of fibrotic diseases |
| CA3009153A1 (en) | 2015-01-30 | 2016-08-04 | The University Of North Carolina At Chapel Hill | Methods to generate gastrointestinal epithelial tissue constructs |
| US11185536B2 (en) | 2015-12-04 | 2021-11-30 | Massachusetts Eye And Ear Infirmary | Treatment of hearing loss by inhibition of casein kinase 1 |
| CN109219439B (zh) | 2016-01-29 | 2022-09-20 | 马萨诸塞眼科耳科诊所 | 内耳支持细胞的扩增和分化及其使用方法 |
| US11180735B2 (en) | 2016-10-28 | 2021-11-23 | The Board Of Trustees Of The Leland Stanford Junior University | Methods to preserve tumor-stromal interactions in culture and therapeutic predictive applications thereof |
| DK3881861T3 (da) | 2017-06-16 | 2024-09-09 | Zealand Pharma As | Doseringsregimer for indgivelse af glukagonlignende peptid-2- (GLP-2)-analoger |
| GB201721615D0 (en) | 2017-12-21 | 2018-02-07 | Koninklijke Nederlandse Akademie Van Wetenschappen | Immune cell organoid co-cultures |
| JP7371012B2 (ja) | 2018-05-15 | 2023-10-30 | ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル | インビトロ細胞培養の為の自己持続型の低酸素状態並びにガス勾配及び非ガス化学勾配を生成するデバイス、システム、及び装置 |
| EP3802848A4 (en) | 2018-05-25 | 2022-03-09 | The University of North Carolina at Chapel Hill | FORMATION OF ARRAYS OF PLANAR INTESTINAL CRYPTS WITH A STEM CELL/PROLIFERATIVE CELL COMPARTMENT AND A DIFFERENTIATED CELL ZONE |
| WO2020102682A1 (en) | 2018-11-16 | 2020-05-22 | The University Of North Carolina At Chapel Hill | In vitro cell culture mucus systems |
| WO2021247497A1 (en) * | 2020-06-03 | 2021-12-09 | Children's Hospital Medical Center | Compositions and methods comprising r-spondins for treatment of tumors |
| CA3219754A1 (en) | 2021-05-21 | 2022-11-24 | Gary Beale | Microwave treatment of tissue |
| US12465781B2 (en) | 2021-06-11 | 2025-11-11 | Joon Bu Park | Negative Poisson's ratio materials for thermal and radiation therapy seeds |
| WO2023097236A1 (en) * | 2021-11-24 | 2023-06-01 | The Rockefeller University | Compositions and methods for generating immunoglobulin knock-in mice |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2198180C2 (ru) * | 1994-10-13 | 2003-02-10 | Амген Инк. | Аналог природного фактора роста кератиноцитов (варианты), фармацевтическая композиция, рекомбинантная молекула нуклеиновой кислоты, кодирующая аналог, экспрессионный вектор, штамм e.coli, трансформированный вектором, способ получения аналога и способ стимулирования образования нефибробластных эпителиальных клеток |
| US6824973B2 (en) * | 2000-02-03 | 2004-11-30 | Kirin Beer Kabushiki Kaisha | Method of promoting stem cell proliferation or survival by contacting a cell with a stem cell factor-like polypeptide |
| CA2405104A1 (en) | 2000-04-05 | 2001-10-18 | Kirin Beer Kabushiki Kaisha | Methods and materials relating to stem cell growth factor-like polypeptides and polynucleotides |
| US20030032034A1 (en) * | 2001-03-05 | 2003-02-13 | Tang Y. Tom | Methods and materials relating to stem cell growth factor-like polypeptides and polynucleotides |
| US7411052B2 (en) * | 2001-03-05 | 2008-08-12 | Nuvelo, Inc. | Methods and materials relating to stem cell growth factor-like polypeptides and polynucleotides |
| ATE553193T1 (de) * | 2001-08-30 | 2012-04-15 | Arca Biopharma Inc | Verfahren und materialien in verbindung mit stammzellen-wachstumsfaktor-ähnlichen polypeptiden und polynukleotiden |
| CA2462795A1 (en) | 2001-10-03 | 2003-04-10 | Incyte Genomics, Inc. | Secreted proteins |
| CA2469941A1 (en) * | 2001-12-10 | 2003-07-03 | Nuvelo, Inc. | Novel nucleic acids and polypeptides |
| US7193069B2 (en) * | 2002-03-22 | 2007-03-20 | Research Association For Biotechnology | Full-length cDNA |
| WO2005110009A2 (en) | 2003-07-22 | 2005-11-24 | Immunex Corporation | COMPOSITIONS AND METHODS RELATING TO TSP-30a, b, c AND d |
| US20050169995A1 (en) * | 2003-10-03 | 2005-08-04 | Kuo Calvin J. | Modulation of gastrointestinal epithelium proliferation through the Wnt signaling pathway |
| EP1673475B1 (en) * | 2003-10-10 | 2010-04-28 | Deutsches Krebsforschungszentrum | Compositions for diagnosis and therapy of diseases associated with aberrant expression of futrins (r-spondins) and/or wnt |
-
2005
- 2005-01-27 JP JP2006551541A patent/JP2007526248A/ja not_active Withdrawn
- 2005-01-27 AU AU2005208945A patent/AU2005208945A1/en not_active Abandoned
- 2005-01-27 BR BRPI0507168-2A patent/BRPI0507168A/pt not_active IP Right Cessation
- 2005-01-27 TW TW094102490A patent/TW200536859A/zh unknown
- 2005-01-27 US US11/046,644 patent/US20050256036A1/en not_active Abandoned
- 2005-01-27 MX MXPA06008495A patent/MXPA06008495A/es not_active Application Discontinuation
- 2005-01-27 RU RU2006130791/13A patent/RU2343158C2/ru active
- 2005-01-27 KR KR1020067017297A patent/KR20070007289A/ko not_active Ceased
- 2005-01-27 US US11/046,456 patent/US20050256044A1/en not_active Abandoned
- 2005-01-27 CA CA002554403A patent/CA2554403A1/en not_active Abandoned
- 2005-01-27 WO PCT/US2005/002996 patent/WO2005072419A2/en not_active Ceased
- 2005-01-27 EP EP05712439A patent/EP1727560B1/en not_active Expired - Lifetime
- 2005-01-27 SG SG200809511-9A patent/SG149059A1/en unknown
-
2006
- 2006-07-25 IL IL177060A patent/IL177060A0/en unknown
- 2006-08-02 NO NO20063522A patent/NO20063522L/no not_active Application Discontinuation
-
2007
- 2007-05-24 US US11/805,883 patent/US20080300183A1/en not_active Abandoned
-
2008
- 2008-09-09 RU RU2008136324/13A patent/RU2008136324A/ru not_active Application Discontinuation
-
2009
- 2009-10-27 US US12/589,727 patent/US7951381B2/en not_active Expired - Fee Related
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