JP2007526248A5 - - Google Patents
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- Publication number
- JP2007526248A5 JP2007526248A5 JP2006551541A JP2006551541A JP2007526248A5 JP 2007526248 A5 JP2007526248 A5 JP 2007526248A5 JP 2006551541 A JP2006551541 A JP 2006551541A JP 2006551541 A JP2006551541 A JP 2006551541A JP 2007526248 A5 JP2007526248 A5 JP 2007526248A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- polypeptide
- amino acid
- acid sequence
- cell proliferation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 10
- 125000003275 alpha amino acid group Chemical group 0.000 claims 8
- 229920001184 polypeptide Polymers 0.000 claims 8
- 102000004196 processed proteins & peptides Human genes 0.000 claims 8
- 108090000765 processed proteins & peptides Proteins 0.000 claims 8
- 230000008556 epithelial cell proliferation Effects 0.000 claims 7
- 230000004936 stimulating effect Effects 0.000 claims 6
- 210000001035 gastrointestinal tract Anatomy 0.000 claims 5
- 201000010099 disease Diseases 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 210000000214 mouth Anatomy 0.000 claims 3
- 238000002512 chemotherapy Methods 0.000 claims 2
- 210000003238 esophagus Anatomy 0.000 claims 2
- 210000002429 large intestine Anatomy 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 238000001959 radiotherapy Methods 0.000 claims 2
- 210000000813 small intestine Anatomy 0.000 claims 2
- 210000002784 stomach Anatomy 0.000 claims 2
- 208000022559 Inflammatory bowel disease Diseases 0.000 claims 1
- 206010028116 Mucosal inflammation Diseases 0.000 claims 1
- 201000010927 Mucositis Diseases 0.000 claims 1
- 206010049416 Short-bowel syndrome Diseases 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53960504P | 2004-01-27 | 2004-01-27 | |
| US60/539,605 | 2004-01-27 | ||
| US61924104P | 2004-10-15 | 2004-10-15 | |
| US60/619,241 | 2004-10-15 | ||
| PCT/US2005/002996 WO2005072419A2 (en) | 2004-01-27 | 2005-01-27 | Gastrointestinal proliferative factor and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007526248A JP2007526248A (ja) | 2007-09-13 |
| JP2007526248A5 true JP2007526248A5 (enExample) | 2009-03-05 |
Family
ID=34830487
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006551541A Withdrawn JP2007526248A (ja) | 2004-01-27 | 2005-01-27 | 胃腸増殖因子およびその使用方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (4) | US20050256044A1 (enExample) |
| EP (1) | EP1727560B1 (enExample) |
| JP (1) | JP2007526248A (enExample) |
| KR (1) | KR20070007289A (enExample) |
| AU (1) | AU2005208945A1 (enExample) |
| BR (1) | BRPI0507168A (enExample) |
| CA (1) | CA2554403A1 (enExample) |
| IL (1) | IL177060A0 (enExample) |
| MX (1) | MXPA06008495A (enExample) |
| NO (1) | NO20063522L (enExample) |
| RU (2) | RU2343158C2 (enExample) |
| SG (1) | SG149059A1 (enExample) |
| TW (1) | TW200536859A (enExample) |
| WO (1) | WO2005072419A2 (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI2157192T1 (sl) * | 2003-10-10 | 2013-11-29 | Deutsches Krebsforschungszentrum | Sestavki za diagnozo in terapijo bolezni, povezanih z aberantno ekspresijo Futrinov (R-Spondinov) |
| US20190330295A1 (en) * | 2005-05-04 | 2019-10-31 | Zealand Pharma A/S | Glucagon-like-peptide-2 (glp-2) analogues |
| JP2009511017A (ja) * | 2005-10-07 | 2009-03-19 | ヌベロ インコーポレーティッド | 幹細胞因子様タンパク質ｓｃｆａ１及びその使用 |
| WO2008076556A2 (en) | 2006-11-15 | 2008-06-26 | Massachusetts Eye & Ear Infirmary | Generation of inner ear cells |
| WO2008088524A2 (en) * | 2006-12-28 | 2008-07-24 | Nuvelo, Inc. | Thrombospondin-domain-deficient r-spondin 1 protein as gastrointestinal tract epithelial proliferation factor |
| SI2173379T1 (sl) | 2007-07-02 | 2015-12-31 | Oncomed Pharmaceuticals, Inc. | Sestavki in postopki za zdravljenje in diagnosticiranje raka |
| US9464275B2 (en) | 2008-08-21 | 2016-10-11 | The Board Of Trustees Of The Leland Stanford Junior University | Ex vivo culture, proliferation and expansion of intestinal epithelium |
| JP5809061B2 (ja) * | 2008-11-24 | 2015-11-10 | マサチューセッツ・アイ・アンド・イア・インファーマリー | 有毛細胞を産生するための経路 |
| SG173492A1 (en) | 2009-02-03 | 2011-09-29 | Koninklijke Nederlandse Akademie Van Wetenschappen | Culture medium for epithelial stem cells and organoids comprising said stem cells. |
| EP2412800A1 (en) | 2010-07-29 | 2012-02-01 | Koninklijke Nederlandse Akademie van Wetenschappen | Liver organoid, uses thereof and culture method for obtaining them |
| US9752124B2 (en) | 2009-02-03 | 2017-09-05 | Koninklijke Nederlandse Akademie Van Wetenschappen | Culture medium for epithelial stem cells and organoids comprising the stem cells |
| IT1396935B1 (it) | 2009-11-26 | 2012-12-20 | Solartium Entpr Ltd | Uso di una combinazione per il trattamento delle mucositi indotte da radiazioni o da chemioterapici |
| RU2532323C2 (ru) * | 2011-06-20 | 2014-11-10 | Мапикс Эс.Эй.Ар.Эл. | Лекарственное средство для лечения патологического синдрома и способ лечения функциональных нарушений кишечника |
| GB201106395D0 (en) * | 2011-04-14 | 2011-06-01 | Hubrecht Inst | Compounds |
| MX349198B (es) | 2011-07-15 | 2017-07-18 | Oncomed Pharmaceuticals Inc * | Agentes que se unen a las proteinas de r-espondinas (rspo) y usos de los mismos. |
| WO2014012007A2 (en) | 2012-07-13 | 2014-01-16 | Oncomed Pharmaceuticals, Inc. | Rspo3 binding agents and uses thereof |
| JP2015527398A (ja) | 2012-09-07 | 2015-09-17 | マサチューセッツ アイ アンド イヤー インファーマリー | 聴覚喪失治療 |
| KR102133789B1 (ko) * | 2013-01-10 | 2020-07-14 | 바이오콘 리미티드 | 유가식 모델을 이용한 피키아 파스토리스에서 재조합 단백질의 발현 방법 |
| WO2016022776A2 (en) | 2014-08-06 | 2016-02-11 | Massachusetts Eye And Ear Infirmary | Increasing atoh1 life to drive sensorineural hair cell differentiantion |
| EP3193935A4 (en) | 2014-09-16 | 2018-03-21 | Oncomed Pharmaceuticals, Inc. | Treatment of fibrotic diseases |
| WO2016123474A1 (en) * | 2015-01-30 | 2016-08-04 | The University Of North Carolina At Chapel Hill | Methods to generate gastrointestinal epithelial tissue constructs |
| US11185536B2 (en) | 2015-12-04 | 2021-11-30 | Massachusetts Eye And Ear Infirmary | Treatment of hearing loss by inhibition of casein kinase 1 |
| JP7080173B2 (ja) | 2016-01-29 | 2022-06-03 | マサチューセッツ アイ アンド イヤー インファーマリー | 内耳支持細胞の拡大および分化ならびにその使用法 |
| US11180735B2 (en) | 2016-10-28 | 2021-11-23 | The Board Of Trustees Of The Leland Stanford Junior University | Methods to preserve tumor-stromal interactions in culture and therapeutic predictive applications thereof |
| TWI791539B (zh) | 2017-06-16 | 2023-02-11 | 丹麥商西蘭製藥公司 | 用於投予類升糖素胜肽-2(glp-2)類似物的給藥方案 |
| US12104149B2 (en) | 2018-05-15 | 2024-10-01 | The University Of North Carolina At Chapel Hill | Devices, systems and apparatuses for generating self-sustaining hypoxic conditions and gaseous and non-gaseous chemical gradients for in vitro cell culture |
| JP7451427B2 (ja) | 2018-05-25 | 2024-03-18 | ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル | 幹細胞／増殖細胞区画及び分化細胞ゾーンを有する平面腸陰窩のアレイの形成 |
| CA3112220A1 (en) | 2018-11-16 | 2020-05-22 | The University Of North Carolina At Chapel Hill | In vitro cell culture mucus systems |
| WO2021247497A1 (en) * | 2020-06-03 | 2021-12-09 | Children's Hospital Medical Center | Compositions and methods comprising r-spondins for treatment of tumors |
| CA3219754A1 (en) | 2021-05-21 | 2022-11-24 | Gary Beale | Microwave treatment of tissue |
| US12465781B2 (en) | 2021-06-11 | 2025-11-11 | Joon Bu Park | Negative Poisson's ratio materials for thermal and radiation therapy seeds |
| WO2023097236A1 (en) * | 2021-11-24 | 2023-06-01 | The Rockefeller University | Compositions and methods for generating immunoglobulin knock-in mice |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2198180C2 (ru) * | 1994-10-13 | 2003-02-10 | Амген Инк. | Аналог природного фактора роста кератиноцитов (варианты), фармацевтическая композиция, рекомбинантная молекула нуклеиновой кислоты, кодирующая аналог, экспрессионный вектор, штамм e.coli, трансформированный вектором, способ получения аналога и способ стимулирования образования нефибробластных эпителиальных клеток |
| US6824973B2 (en) * | 2000-02-03 | 2004-11-30 | Kirin Beer Kabushiki Kaisha | Method of promoting stem cell proliferation or survival by contacting a cell with a stem cell factor-like polypeptide |
| EP1268543A2 (en) | 2000-04-05 | 2003-01-02 | Kirin Beer Kabushiki Kaisha | Methods and materials relating to stem cell growth factor-like polypeptides and polynucleotides |
| US7411052B2 (en) * | 2001-03-05 | 2008-08-12 | Nuvelo, Inc. | Methods and materials relating to stem cell growth factor-like polypeptides and polynucleotides |
| US20030032034A1 (en) * | 2001-03-05 | 2003-02-13 | Tang Y. Tom | Methods and materials relating to stem cell growth factor-like polypeptides and polynucleotides |
| AU2002332767A1 (en) * | 2001-08-30 | 2003-04-14 | Nuvelo | Methods and materials relating to stem cell growth factor-like polypeptides and polynucleotides |
| EP1434796A2 (en) | 2001-10-03 | 2004-07-07 | Incyte Genomics, Inc. | Secreted proteins |
| WO2003054152A2 (en) * | 2001-12-10 | 2003-07-03 | Nuvelo, Inc. | Novel nucleic acids and polypeptides |
| US7193069B2 (en) * | 2002-03-22 | 2007-03-20 | Research Association For Biotechnology | Full-length cDNA |
| US20050054829A1 (en) * | 2003-07-22 | 2005-03-10 | Wiley Steven R. | Compositions and methods relating to TSP-30a, b, c and d |
| US20050169995A1 (en) * | 2003-10-03 | 2005-08-04 | Kuo Calvin J. | Modulation of gastrointestinal epithelium proliferation through the Wnt signaling pathway |
| SI2157192T1 (sl) * | 2003-10-10 | 2013-11-29 | Deutsches Krebsforschungszentrum | Sestavki za diagnozo in terapijo bolezni, povezanih z aberantno ekspresijo Futrinov (R-Spondinov) |
-
2005
- 2005-01-27 AU AU2005208945A patent/AU2005208945A1/en not_active Abandoned
- 2005-01-27 US US11/046,456 patent/US20050256044A1/en not_active Abandoned
- 2005-01-27 KR KR1020067017297A patent/KR20070007289A/ko not_active Ceased
- 2005-01-27 TW TW094102490A patent/TW200536859A/zh unknown
- 2005-01-27 BR BRPI0507168-2A patent/BRPI0507168A/pt not_active IP Right Cessation
- 2005-01-27 MX MXPA06008495A patent/MXPA06008495A/es not_active Application Discontinuation
- 2005-01-27 SG SG200809511-9A patent/SG149059A1/en unknown
- 2005-01-27 JP JP2006551541A patent/JP2007526248A/ja not_active Withdrawn
- 2005-01-27 CA CA002554403A patent/CA2554403A1/en not_active Abandoned
- 2005-01-27 US US11/046,644 patent/US20050256036A1/en not_active Abandoned
- 2005-01-27 EP EP05712439A patent/EP1727560B1/en not_active Expired - Lifetime
- 2005-01-27 WO PCT/US2005/002996 patent/WO2005072419A2/en not_active Ceased
- 2005-01-27 RU RU2006130791/13A patent/RU2343158C2/ru active
-
2006
- 2006-07-25 IL IL177060A patent/IL177060A0/en unknown
- 2006-08-02 NO NO20063522A patent/NO20063522L/no not_active Application Discontinuation
-
2007
- 2007-05-24 US US11/805,883 patent/US20080300183A1/en not_active Abandoned
-
2008
- 2008-09-09 RU RU2008136324/13A patent/RU2008136324A/ru not_active Application Discontinuation
-
2009
- 2009-10-27 US US12/589,727 patent/US7951381B2/en not_active Expired - Fee Related
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