JP2009501801A5 - - Google Patents
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- Publication number
- JP2009501801A5 JP2009501801A5 JP2008522937A JP2008522937A JP2009501801A5 JP 2009501801 A5 JP2009501801 A5 JP 2009501801A5 JP 2008522937 A JP2008522937 A JP 2008522937A JP 2008522937 A JP2008522937 A JP 2008522937A JP 2009501801 A5 JP2009501801 A5 JP 2009501801A5
- Authority
- JP
- Japan
- Prior art keywords
- dosage form
- ibuprofen
- famotidine
- oral dosage
- use according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000006186 oral dosage form Substances 0.000 claims 15
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 claims 14
- 229960001680 ibuprofen Drugs 0.000 claims 14
- XUFQPHANEAPEMJ-UHFFFAOYSA-N famotidine Chemical compound NC(N)=NC1=NC(CSCCC(N)=NS(N)(=O)=O)=CS1 XUFQPHANEAPEMJ-UHFFFAOYSA-N 0.000 claims 10
- 229960001596 famotidine Drugs 0.000 claims 10
- 239000002552 dosage form Substances 0.000 claims 5
- AULFVKUUIUIWQU-UHFFFAOYSA-N 3-[[2-(diaminomethylideneamino)-1,3-thiazol-4-yl]methylsulfanyl]-n'-sulfamoylpropanimidamide;2-[4-(2-methylpropyl)phenyl]propanoic acid Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1.NC(N)=NC1=NC(CSCC\C(N)=N\S(N)(=O)=O)=CS1 AULFVKUUIUIWQU-UHFFFAOYSA-N 0.000 claims 3
- 208000002193 Pain Diseases 0.000 claims 2
- 230000001684 chronic effect Effects 0.000 claims 2
- 230000002496 gastric effect Effects 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- 208000024891 symptom Diseases 0.000 claims 2
- 208000000094 Chronic Pain Diseases 0.000 claims 1
- 208000005171 Dysmenorrhea Diseases 0.000 claims 1
- 206010013935 Dysmenorrhoea Diseases 0.000 claims 1
- 208000025865 Ulcer Diseases 0.000 claims 1
- 208000038016 acute inflammation Diseases 0.000 claims 1
- 230000006022 acute inflammation Effects 0.000 claims 1
- 208000005298 acute pain Diseases 0.000 claims 1
- 238000004090 dissolution Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 claims 1
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 claims 1
- 201000008482 osteoarthritis Diseases 0.000 claims 1
- 239000008057 potassium phosphate buffer Substances 0.000 claims 1
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 1
- 231100000397 ulcer Toxicity 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70048105P | 2005-07-18 | 2005-07-18 | |
| PCT/US2006/028075 WO2007012019A2 (en) | 2005-07-18 | 2006-07-18 | Medicaments containing famotidine and ibuprofen and administration of same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009501801A JP2009501801A (ja) | 2009-01-22 |
| JP2009501801A5 true JP2009501801A5 (enExample) | 2009-08-27 |
Family
ID=37669550
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008522937A Pending JP2009501801A (ja) | 2005-07-18 | 2006-07-18 | イブプロフェンとファモチジンとを含有する医薬およびその投与 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20070043097A1 (enExample) |
| EP (1) | EP1919288A4 (enExample) |
| JP (1) | JP2009501801A (enExample) |
| CN (1) | CN101257800B (enExample) |
| CA (1) | CA2615496C (enExample) |
| IL (1) | IL188732A (enExample) |
| NZ (1) | NZ565846A (enExample) |
| WO (2) | WO2007012019A2 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3516632B2 (ja) | 2000-04-27 | 2004-04-05 | オリジン電気株式会社 | 光ディスク基板の貼り合わせ方法及び装置 |
| US20080020040A1 (en) * | 2006-07-18 | 2008-01-24 | Horizon Therapeutics, Inc. | Unit dose form for administration of ibuprofen |
| US20080021078A1 (en) * | 2006-07-18 | 2008-01-24 | Horizon Therapeutics, Inc. | Methods and medicaments for administration of ibuprofen |
| US8067451B2 (en) | 2006-07-18 | 2011-11-29 | Horizon Pharma Usa, Inc. | Methods and medicaments for administration of ibuprofen |
| JP2009543885A (ja) * | 2006-07-18 | 2009-12-10 | ホライゾン セラピューティクス， インコーポレイテッド | イブプロフェンの投与のための方法および医薬 |
| US8067033B2 (en) | 2007-11-30 | 2011-11-29 | Horizon Pharma Usa, Inc. | Stable compositions of famotidine and ibuprofen |
| US20150224056A1 (en) * | 2006-07-18 | 2015-08-13 | Horizon Pharma Usa, Inc. | Pharmaceutical compositions of ibuprofen and famotidine |
| EP2063873A2 (en) * | 2006-08-31 | 2009-06-03 | Horizon Therapeutics, Inc. | Nsaid dose unit formulations with h2-receptor antagonists and methods of use |
| WO2008091957A2 (en) * | 2007-01-24 | 2008-07-31 | Horizon Therapeutics, Inc. | Pharmaceutical compositions containing famotidine and ibuprofen and having improved content uniformity |
| EP3090739A1 (en) * | 2008-01-04 | 2016-11-09 | Schabar Research Associates LLC | Compositions composed of naproxen sodium and nizatidine |
| US9629809B2 (en) | 2008-07-21 | 2017-04-25 | Si Group, Inc. | High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms |
| EP2309988B1 (en) * | 2008-07-21 | 2015-11-25 | SI Group, Inc. | High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms |
| WO2012003181A2 (en) * | 2010-07-02 | 2012-01-05 | Fmc Corporation | Solid forms |
| WO2013054352A1 (en) | 2011-08-17 | 2013-04-18 | Cadila Healthcare Limited | Pharmaceutical compositions of ibuprofen and famotidine |
| CN102247371A (zh) * | 2011-08-19 | 2011-11-23 | 北京阜康仁生物制药科技有限公司 | 一种以布洛芬和拉呋替丁为活性成分的药物组合物 |
| CN103083314A (zh) * | 2011-10-28 | 2013-05-08 | 四川大学 | 具有胃肠道保护作用的复方布洛芬 |
| WO2015163832A1 (en) | 2014-04-25 | 2015-10-29 | Pharmacti̇ve İlaç Sanayi̇ Ve Ti̇caret A.Ş. | An ibuprofen and famotidine combined composition having improved stability |
| EP3368029A1 (en) * | 2015-10-30 | 2018-09-05 | Cancer Prevention Pharmaceuticals, Inc. | Eflornithine and sulindac, fixed dose combination formulation |
| CN116730921A (zh) | 2017-02-17 | 2023-09-12 | 文涵治疗有限公司 | Ag-10的制备方法、其中间体及其盐 |
| MA52137A (fr) | 2018-03-23 | 2021-01-27 | Eidos Therapeutics Inc | Méthodes de traitement de l'amylose ttr à l'aide d'ag10 |
| JP7469293B2 (ja) | 2018-08-17 | 2024-04-16 | エイドス セラピューティクス，インコーポレイティド | Ａｇ１０の製剤 |
| US12514846B2 (en) | 2020-07-15 | 2026-01-06 | Schabar Research Associates Llc | Unit oral dose compositions composed of ibuprofen or a pharmaceutically acceptable salt thereof and famotidine or a pharmaceutically acceptable salt thereof for the treatment of acute pain and the reduction of the severity and/or risk of heartburn and/or upset stomach |
| CA3124579A1 (en) | 2020-07-15 | 2022-01-15 | Schabar Research Associates Llc | Unit oral dose compositions composed of naproxen sodium and famotidine for the treatment of acute pain and the reduction of the severity of heartburn and/or the risk of heartburn |
| IL299845A (en) | 2020-07-15 | 2023-03-01 | Schabar Res Associates Llc | Unit oral dose compositions composed of ibuprofen and famotidine for the treatment of acute pain and the reduction of the severity and/or risk of heartburn |
| AU2022244333A1 (en) * | 2021-03-24 | 2023-11-09 | Kenvue Brands Llc | A pharmaceutical composition comprising famotidine |
| US12303604B1 (en) | 2024-10-16 | 2025-05-20 | Currax Pharmaceuticals Llc | Pharmaceutical formulations comprising naltrexone and/or bupropion |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6056143B2 (ja) * | 1979-08-02 | 1985-12-09 | 山之内製薬株式会社 | アミジン誘導体ならびにその製造法 |
| US4543370A (en) | 1979-11-29 | 1985-09-24 | Colorcon, Inc. | Dry edible film coating composition, method and coating form |
| US5037815A (en) * | 1986-03-04 | 1991-08-06 | Bristol-Myers Squibb Co. | Non-steroidal anti-inflammatory compositions protected against gastrointestinal injury with a combination of certain H1 - and H2 -receptor blockers |
| HU196775B (en) * | 1986-08-05 | 1989-01-30 | Richter Gedeon Vegyeszet | Process for production of morfologically unique new modifications of famotidin and medical compositions containing such substances |
| US5204118A (en) * | 1989-11-02 | 1993-04-20 | Mcneil-Ppc, Inc. | Pharmaceutical compositions and methods for treating the symptoms of overindulgence |
| JP2542122B2 (ja) * | 1990-04-18 | 1996-10-09 | 旭化成工業株式会社 | 球状核、球形顆粒およびその製造方法 |
| EP0452862B1 (en) * | 1990-04-18 | 1995-07-19 | Asahi Kasei Kogyo Kabushiki Kaisha | Spherical seed cores, spherical granules and process for production thereof |
| SK279279B6 (sk) * | 1991-05-13 | 1998-09-09 | The Boots Company Plc | S(-)-nátrium-2-(4-izobutylfenyl)propionát-dihydrát |
| ES2130152T3 (es) * | 1991-12-06 | 1999-07-01 | Glaxo Group Ltd | Medicamentos para tratar dolencias inflamatorias o para analgesia que contienen un nsaid y ranitidina/citrato de bismuto. |
| WO1994007541A1 (en) * | 1992-09-29 | 1994-04-14 | Merck & Co., Inc. | Ibuprofen-h2 antagonist combinations |
| DK0607467T3 (da) * | 1992-12-01 | 1999-12-13 | Spirig Ag | Lægemidler, der indeholder S(+)-ibuprofen |
| US5496836A (en) * | 1994-05-05 | 1996-03-05 | Mount Sinai School Of Medicine Of The City University Of New York | Use of famotidine and related compounds in the treatment of movement disorders |
| ES2082723B1 (es) * | 1994-07-20 | 1996-10-01 | Lilly Sa | Formulacion farmaceutica de fluoxetina en forma dispersable. |
| DE19509805A1 (de) * | 1995-03-21 | 1996-09-26 | Basf Ag | Transparente, schnell freisetzende Zubereitungen von nichtsteroidalen Analgetica |
| US5854267A (en) * | 1995-06-02 | 1998-12-29 | Merck & Co., Inc. | Method for preventing heartburn |
| SE9600070D0 (sv) * | 1996-01-08 | 1996-01-08 | Astra Ab | New oral pharmaceutical dosage forms |
| US6239124B1 (en) * | 1996-07-30 | 2001-05-29 | Novartis Ag | Pharmaceutical compositions for the treatment of transplant rejection or autoimmune or inflammatory conditions comprising cyclosporin A and 40-0-(2-hydroxyethyl)-rapamycin |
| US5997905A (en) * | 1998-09-04 | 1999-12-07 | Mcneil-Ppc | Preparation of pharmaceutically active particles |
| FR2785539B1 (fr) * | 1998-11-06 | 2004-04-09 | Prographarm Laboratoires | Particules enrobees d'ibuprofene cristallin granule |
| CA2349575A1 (en) * | 1998-11-17 | 2000-05-25 | Nitromed, Inc. | Nitrosated and nitrosylated h2 receptor antagonist compounds, compositions and methods of use |
| US6294192B1 (en) * | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
| US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| US20030178031A1 (en) * | 1999-05-07 | 2003-09-25 | Du Pen, Inc. | Method for cancer pain treatment |
| MXPA02005562A (es) * | 1999-12-06 | 2004-09-10 | Penwest Pharmaceuticals Co | Superdesintegrante farmaceutico. |
| PT1411900E (pt) * | 2001-06-01 | 2010-10-11 | Pozen Inc | Composições farmacêuticas para a entrega coordenada de aines |
| GB0124459D0 (en) * | 2001-10-11 | 2001-12-05 | Novartis Ag | Organic compounds |
| AR043444A1 (es) * | 2003-03-05 | 2005-07-27 | Merck Frosst Canada Inc | Profarmacos de diaril-2- 5h -furanonas que liberan oxido nitrico como inhibidores de la ciclooxigenasa-2 |
| US20050053655A1 (en) * | 2003-09-05 | 2005-03-10 | Pharmaceutical Industry Technology And Development Center | Rapid disintegrating tablets (RDTs) for pharmaceutical use and method for preparing the same |
| US8734850B2 (en) * | 2003-11-25 | 2014-05-27 | Flamel Technologies | Oral medicinal product with modified release of at least one active principle in multimicrocapsular form |
| US20050163847A1 (en) * | 2004-01-21 | 2005-07-28 | Andrx Pharmaceuticals, Llc | Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and an antiulcerative drug |
| EP1718303A4 (en) * | 2004-02-10 | 2010-09-01 | Santarus Inc | COMBINATION OF INHIBITOR OF PROTON PUMP, BUFFER AND NON-STEROIDAL ANTI-INFLAMMATORY DRUG |
| US20060177504A1 (en) * | 2005-02-08 | 2006-08-10 | Renjit Sundharadas | Combination pain medication |
| CA2511158A1 (en) * | 2005-06-29 | 2006-12-29 | Medical Futures Inc. | Medicated gumstick for treatment in anti-inflammatory conditions and prophylaxis against nsaid gastropathy |
| US20080021078A1 (en) * | 2006-07-18 | 2008-01-24 | Horizon Therapeutics, Inc. | Methods and medicaments for administration of ibuprofen |
| US8067451B2 (en) * | 2006-07-18 | 2011-11-29 | Horizon Pharma Usa, Inc. | Methods and medicaments for administration of ibuprofen |
-
2006
- 2006-07-18 US US11/489,705 patent/US20070043097A1/en not_active Abandoned
- 2006-07-18 CA CA2615496A patent/CA2615496C/en not_active Expired - Fee Related
- 2006-07-18 WO PCT/US2006/028075 patent/WO2007012019A2/en not_active Ceased
- 2006-07-18 EP EP06800140A patent/EP1919288A4/en not_active Withdrawn
- 2006-07-18 WO PCT/US2006/028078 patent/WO2007012022A2/en not_active Ceased
- 2006-07-18 NZ NZ565846A patent/NZ565846A/en not_active IP Right Cessation
- 2006-07-18 JP JP2008522937A patent/JP2009501801A/ja active Pending
- 2006-07-18 US US11/489,275 patent/US20070043096A1/en not_active Abandoned
- 2006-07-18 CN CN2006800324428A patent/CN101257800B/zh not_active Expired - Fee Related
-
2008
- 2008-01-13 IL IL188732A patent/IL188732A/en not_active IP Right Cessation
-
2013
- 2013-02-15 US US13/769,196 patent/US20140066485A1/en not_active Abandoned
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