HK1258284A1 - 依氟鳥氨酸和舒林酸,固定劑量的組合製劑 - Google Patents
依氟鳥氨酸和舒林酸,固定劑量的組合製劑Info
- Publication number
- HK1258284A1 HK1258284A1 HK19100648.5A HK19100648A HK1258284A1 HK 1258284 A1 HK1258284 A1 HK 1258284A1 HK 19100648 A HK19100648 A HK 19100648A HK 1258284 A1 HK1258284 A1 HK 1258284A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- eflornithine
- sulindac
- fixed dose
- dose combination
- combination formulation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
- A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2813—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562248810P | 2015-10-30 | 2015-10-30 | |
US201662358698P | 2016-07-06 | 2016-07-06 | |
EP16306430 | 2016-10-28 | ||
EP16306429 | 2016-10-28 | ||
PCT/US2016/059689 WO2017075576A1 (en) | 2015-10-30 | 2016-10-31 | Eflornithine and sulindac, fixed dose combination formulation |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1258284A1 true HK1258284A1 (zh) | 2019-11-08 |
Family
ID=57256487
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK19100648.5A HK1258284A1 (zh) | 2015-10-30 | 2019-01-15 | 依氟鳥氨酸和舒林酸,固定劑量的組合製劑 |
Country Status (14)
Country | Link |
---|---|
US (3) | US10973790B2 (zh) |
EP (1) | EP3368029A1 (zh) |
JP (2) | JP2018536707A (zh) |
KR (1) | KR20180069068A (zh) |
CN (1) | CN108366982A (zh) |
AU (1) | AU2016343851B2 (zh) |
BR (1) | BR112018008651A2 (zh) |
CA (1) | CA3003149C (zh) |
CL (1) | CL2018001157A1 (zh) |
CO (1) | CO2018005491A2 (zh) |
HK (1) | HK1258284A1 (zh) |
IL (1) | IL259009A (zh) |
MA (1) | MA43114A (zh) |
MX (1) | MX2018005350A (zh) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR112018008651A2 (pt) | 2015-10-30 | 2018-10-30 | Cancer Prevention Pharmaceuticals Inc | formulação de combinação de dose fixa de eflornitina e sulindaco |
EP3523274A4 (en) * | 2016-10-06 | 2020-05-13 | Orbus Therapeutics, Inc. | FORMULATIONS FOR THE ADMINISTRATION OF EFLORNITHIN |
CN114096240A (zh) * | 2019-05-17 | 2022-02-25 | 癌症预防制药股份有限公司 | 用于治疗家族性腺瘤性息肉病的方法 |
Family Cites Families (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4309442A (en) * | 1977-07-11 | 1982-01-05 | Merrell Toraude Et Compagnie | Method for controlling fertility in mammals |
US4330559A (en) | 1977-07-11 | 1982-05-18 | Merrell-Toraude Et Cie | Method of treating benign prostatic hypertrophy |
US4413141A (en) | 1977-07-11 | 1983-11-01 | Merrell Toraude Et Compagnie | 2-(Difluoromethyl)-2,5-diaminopentanoic acid |
US4499072A (en) | 1982-11-29 | 1985-02-12 | Merrell Dow Pharmaceuticals Inc. | Process for treating diseases with ODC inhibitors |
US4859452A (en) | 1986-01-17 | 1989-08-22 | Board Of Regents, The University Of Texas System | Methods for the reduction of difluoromethylornithine associated toxicity |
US4925835A (en) | 1986-05-01 | 1990-05-15 | Sloan-Kettering Institute For Cancer Research | Aziridinyl putrescine containing compositions and their uses in treating prostate cancer |
US5002879A (en) | 1986-05-06 | 1991-03-26 | Merrell Dow Pharmaceuticals | Treatment of tumors with autologous LAK cells, interleukin-2 and an ornithine decarboxylase inhibitor |
FR2706255B1 (fr) | 1993-06-17 | 1995-10-27 | Univ Rennes | Composition à usage alimentaire et/ou pharmaceutique pauvre en polyamines et applications thérapeutiques. |
US5843929A (en) | 1996-03-22 | 1998-12-01 | Mayo Foundation For Medical Education And Research | Chemoprevention of metachronous adenomatous colorectal polyps |
CA2241896A1 (en) * | 1996-11-01 | 1998-05-14 | Ze'ev Shaked | Sustained release formulation containing dfmo |
US6486214B1 (en) | 1997-09-10 | 2002-11-26 | Rutgers, The State University Of New Jersey | Polyanhydride linkers for production of drug polymers and drug polymer compositions produced thereby |
US6258845B1 (en) | 1998-03-28 | 2001-07-10 | The Regents Of The University Of California | DFMO and sulindac combination in cancer chemoprevention |
US7700568B2 (en) | 1998-06-30 | 2010-04-20 | Sloan-Kettering Institute For Cancer Research | Uses of DNA-PK |
US20050037090A1 (en) | 1998-12-23 | 2005-02-17 | Mckearn John P. | Combination therapy including a cyclooxygenase-2 inhibitor and an antineoplastic agent |
AU2713600A (en) | 1998-12-23 | 2000-07-31 | G.D. Searle & Co. | Use of a matrix metalloproteinase inhibitor and an integrin antagonist in the treatment of neoplasia |
US6753422B2 (en) | 1999-03-01 | 2004-06-22 | O'brien Thomas G. | Odc allelic analysis method for assessing carcinogenic susceptibility |
CA2373931A1 (en) | 1999-05-17 | 2000-11-23 | Richard Love | Dfmo and celecoxib in combination for cancer chemoprevention and therapy |
WO2001068076A2 (en) | 2000-03-07 | 2001-09-20 | Ilex Oncology, Inc. | D-enantiomer of dfmo and methods of use thereof for treating cancer |
US6602910B2 (en) | 2000-03-07 | 2003-08-05 | Ilex Oncology, Inc. | D-enantiomer of DFMO and methods of use therefor |
JP2004506683A (ja) | 2000-08-24 | 2004-03-04 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | α−ジフルオロメチルオルニチン(DFMO)は、ヒト前立腺におけるポリアミンレベルを抑制する |
GB0125492D0 (en) | 2001-10-24 | 2001-12-12 | Astrazeneca Ab | Formulation |
US7273888B2 (en) | 2001-11-16 | 2007-09-25 | Als Therapy Development Foundation, Inc. | Use of difluoromethylornithine (DFMO) for the treatment of amyotrophic lateral sclerosis |
EP1575584A4 (en) | 2002-11-29 | 2006-02-01 | Forest Laboratories | METHOD FOR THE TREATMENT OF ACUTE CHARACTERIZATION BY UNIFORM FORMING WITH IBUPROFEN AND OXYCODON |
US20100009929A1 (en) | 2004-03-29 | 2010-01-14 | Cheng Jin Q | Compositions including triciribine and bortezomib and derivatives thereof and methods of use thereof |
US20070043096A1 (en) * | 2005-07-18 | 2007-02-22 | Horizon Therapeutics, Inc. | Unit dose form with ibuprofen-famotidine admixture |
WO2007075673A1 (en) | 2005-12-20 | 2007-07-05 | University Of Hawaii | Treatment regimen for n-myc, c-myc, and l-myc amplified and overexpressed tumors |
ES2380747T3 (es) | 2006-07-18 | 2012-05-18 | Horizon Pharma Usa, Inc. | Métodos y medicamentos para administración de ibuprofeno |
JO3272B1 (ar) * | 2007-07-19 | 2018-09-16 | Takeda Pharmaceuticals Co | مستحضر صلب يشمل ألوجليبتين وميتفورمين هيدروكلوريد |
BRPI0815051A2 (pt) | 2007-08-01 | 2015-02-10 | Sigma Tau Ind Farmaceuti | Tratamento de tumores pediátricos |
WO2009022670A1 (ja) * | 2007-08-10 | 2009-02-19 | Takeda Pharmaceutical Company Limited | 速崩壊性錠剤 |
US8283331B2 (en) | 2007-10-09 | 2012-10-09 | Children's Medical Center Corporation | Methods to regulate miRNA processing by targeting Lin-28 |
CA2753844A1 (en) | 2008-03-05 | 2009-09-11 | Vicus Therapeutics, Llc | Compositions and methods for mucositis and oncology therapies |
WO2010056919A2 (en) * | 2008-11-12 | 2010-05-20 | Kyphia Pharmaceuticals, Inc. | Eflornithine prodrugs, conjugates and salts, and methods of use thereof |
AU2009333510A1 (en) | 2008-12-08 | 2011-06-30 | The Procter & Gamble Company | Personal care composition in the form of an article having a hydrophobic surface-resident coating |
EP2430452B1 (en) | 2009-05-14 | 2014-06-25 | Arizona Board of Regents on Behalf of University of Arizona | Carcinoma diagnosis and treatments, based on odc1 genotype |
SG2014011969A (en) | 2009-05-20 | 2014-09-26 | Ranbaxy Lab Ltd | Liquid dosage forms of isotretinoin |
CN101898978A (zh) | 2009-05-31 | 2010-12-01 | 徐锋 | 依氟鸟氨酸前药和偶合物及其使用方法 |
US20110256161A1 (en) | 2010-04-19 | 2011-10-20 | Aminex Therapeutics Inc. | Methods for enhancing immune response |
AU2011246976B2 (en) | 2010-04-29 | 2016-01-28 | Allarity Therapeutics Europe ApS | Methods and devices for predicting treatment efficacy |
US20130217743A1 (en) | 2010-05-14 | 2013-08-22 | Cancer Prevention Pharmaceuticals, Inc. | Cancer prevention and treatment methods based on dietary polyamine content |
US8853423B2 (en) * | 2010-06-17 | 2014-10-07 | Seragon Pharmaceuticals, Inc. | Indane estrogen receptor modulators and uses thereof |
KR101834026B1 (ko) | 2010-06-19 | 2018-03-02 | 메모리얼 슬로안-케터링 캔서 센터 | 항-gd2 항체 |
LT2912193T (lt) | 2012-10-29 | 2018-12-27 | Arizona Board Of Regents On Behalf Of University Of Arizona | Prognozuojami žymenys, skirti vėžio terapijoms poliamino inhibitoriumi |
GB2513299A (en) | 2013-03-12 | 2014-10-29 | Cellact Pharma Gmbh Biomedizinzentrum | Compounds for targeting cancer stem cells |
CA2926650A1 (en) * | 2013-10-07 | 2015-04-16 | Bristol-Myers Squibb Holdings Ireland | Hiv treatment formulation of atazanavir and cobicistat |
KR20150079373A (ko) * | 2013-12-30 | 2015-07-08 | 한미약품 주식회사 | 에제티미브 및 로수바스타틴을 포함하는 경구용 복합제제 |
US10655183B2 (en) | 2014-06-18 | 2020-05-19 | Arizona Board Of Regents On Behalf Of University Of Arizona | Carcinoma diagnosis and treatment based on ODC1 genotype |
US20190046484A1 (en) | 2015-02-12 | 2019-02-14 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Methods for treating neuroblastoma |
WO2017075576A1 (en) | 2015-10-30 | 2017-05-04 | Cancer Prevention Pharmaceuticals, Inc. | Eflornithine and sulindac, fixed dose combination formulation |
BR112018008651A2 (pt) | 2015-10-30 | 2018-10-30 | Cancer Prevention Pharmaceuticals Inc | formulação de combinação de dose fixa de eflornitina e sulindaco |
-
2016
- 2016-10-31 BR BR112018008651A patent/BR112018008651A2/pt not_active IP Right Cessation
- 2016-10-31 MA MA043114A patent/MA43114A/fr unknown
- 2016-10-31 JP JP2018543001A patent/JP2018536707A/ja not_active Withdrawn
- 2016-10-31 EP EP16794183.0A patent/EP3368029A1/en active Pending
- 2016-10-31 MX MX2018005350A patent/MX2018005350A/es unknown
- 2016-10-31 CA CA3003149A patent/CA3003149C/en active Active
- 2016-10-31 CN CN201680071715.3A patent/CN108366982A/zh active Pending
- 2016-10-31 US US15/771,484 patent/US10973790B2/en active Active
- 2016-10-31 AU AU2016343851A patent/AU2016343851B2/en active Active
- 2016-10-31 KR KR1020187015233A patent/KR20180069068A/ko not_active Application Discontinuation
-
2018
- 2018-04-29 IL IL259009A patent/IL259009A/en unknown
- 2018-04-30 CL CL2018001157A patent/CL2018001157A1/es unknown
- 2018-05-25 CO CONC2018/0005491A patent/CO2018005491A2/es unknown
-
2019
- 2019-01-15 HK HK19100648.5A patent/HK1258284A1/zh unknown
-
2021
- 2021-03-05 US US17/193,588 patent/US11529326B2/en active Active
- 2021-11-17 JP JP2021186911A patent/JP2022028814A/ja active Pending
-
2022
- 2022-11-15 US US18/055,494 patent/US11925613B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
MX2018005350A (es) | 2018-08-14 |
IL259009A (en) | 2018-07-31 |
CA3003149A1 (en) | 2017-05-04 |
CN108366982A (zh) | 2018-08-03 |
CO2018005491A2 (es) | 2018-06-12 |
EP3368029A1 (en) | 2018-09-05 |
AU2016343851B2 (en) | 2022-04-07 |
JP2018536707A (ja) | 2018-12-13 |
BR112018008651A2 (pt) | 2018-10-30 |
US10973790B2 (en) | 2021-04-13 |
CL2018001157A1 (es) | 2018-09-07 |
US20200009098A1 (en) | 2020-01-09 |
MA43114A (fr) | 2018-09-05 |
US20230172887A1 (en) | 2023-06-08 |
US11925613B2 (en) | 2024-03-12 |
CA3003149C (en) | 2023-10-31 |
AU2016343851A1 (en) | 2018-05-10 |
JP2022028814A (ja) | 2022-02-16 |
KR20180069068A (ko) | 2018-06-22 |
US11529326B2 (en) | 2022-12-20 |
US20210267926A1 (en) | 2021-09-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1258290A1 (zh) | 美容器 | |
HK1247614A1 (zh) | 治療化合物及其用途 | |
HK1251183A1 (zh) | 生物綴合物及其用途 | |
GB201520649D0 (en) | Sonodynamic therapy | |
SG11201706029VA (en) | Anti-senescence compounds and uses thereof | |
HK1246780A1 (zh) | 氮雜-吡啶酮化合物及其用途 | |
HK1248697A1 (zh) | 治療化合物及其用途 | |
IL258511B (en) | Compounds and their medicinal uses | |
ZA201705456B (en) | Benzoxaborole compounds and uses thereof | |
GB201514758D0 (en) | Formulation | |
GB201504763D0 (en) | Compounds and uses | |
HK1248209A1 (zh) | 尿素衍生物和其用途 | |
HK1247122A1 (zh) | 組合及其用途 | |
HK1258284A1 (zh) | 依氟鳥氨酸和舒林酸,固定劑量的組合製劑 | |
IL254241A0 (en) | Etv2 and its uses | |
IL253459A0 (en) | Isoergoline compounds and their uses | |
LT3173071T (lt) | Maropitanto kompozicija | |
GB201718875D0 (en) | Autophagy-inhibiting compounds and uses thereof | |
GB201521771D0 (en) | Formulation | |
GB201511255D0 (en) | Formulation | |
GB201509891D0 (en) | Formulation | |
HK1248208A1 (zh) | 尿素衍生物和其用途 | |
IL258458B (en) | Peroxyhemiacetal profragrant and proflavor compounds | |
GB2545167B (en) | Cloches and use thereof | |
GB201512796D0 (en) | P9 |