JP2018038436A5 - - Google Patents

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Publication number
JP2018038436A5
JP2018038436A5 JP2017241315A JP2017241315A JP2018038436A5 JP 2018038436 A5 JP2018038436 A5 JP 2018038436A5 JP 2017241315 A JP2017241315 A JP 2017241315A JP 2017241315 A JP2017241315 A JP 2017241315A JP 2018038436 A5 JP2018038436 A5 JP 2018038436A5
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JP
Japan
Prior art keywords
il1rn
genotype
subject
osteoarthritis
allele
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2017241315A
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English (en)
Japanese (ja)
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JP2018038436A (ja
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Publication date
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Publication of JP2018038436A publication Critical patent/JP2018038436A/ja
Publication of JP2018038436A5 publication Critical patent/JP2018038436A5/ja
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JP2017241315A 2008-05-02 2017-12-18 変形性関節症に関連する状態に対する遺伝的素因の検出 Withdrawn JP2018038436A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US4999208P 2008-05-02 2008-05-02
US61/049,992 2008-05-02
US11874408P 2008-12-01 2008-12-01
US61/118,744 2008-12-01

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2015116397A Division JP6263499B2 (ja) 2008-05-02 2015-06-09 変形性関節症に関連する状態に対する遺伝的素因の検出

Publications (2)

Publication Number Publication Date
JP2018038436A JP2018038436A (ja) 2018-03-15
JP2018038436A5 true JP2018038436A5 (enExample) 2018-11-01

Family

ID=41210581

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2011507714A Active JP5762282B2 (ja) 2008-05-02 2009-05-04 変形性関節症に関連する状態に対する遺伝的素因の検出
JP2015116397A Active JP6263499B2 (ja) 2008-05-02 2015-06-09 変形性関節症に関連する状態に対する遺伝的素因の検出
JP2017241315A Withdrawn JP2018038436A (ja) 2008-05-02 2017-12-18 変形性関節症に関連する状態に対する遺伝的素因の検出

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP2011507714A Active JP5762282B2 (ja) 2008-05-02 2009-05-04 変形性関節症に関連する状態に対する遺伝的素因の検出
JP2015116397A Active JP6263499B2 (ja) 2008-05-02 2015-06-09 変形性関節症に関連する状態に対する遺伝的素因の検出

Country Status (9)

Country Link
US (2) US20100098775A1 (enExample)
EP (3) EP3467126A1 (enExample)
JP (3) JP5762282B2 (enExample)
AU (1) AU2009242490B2 (enExample)
CA (1) CA2723239C (enExample)
DK (2) DK2283156T3 (enExample)
ES (2) ES2708826T3 (enExample)
NZ (1) NZ589034A (enExample)
WO (1) WO2009135218A2 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2708826T3 (es) * 2008-05-02 2019-04-11 Orig3N Inc Detección de la predisposición genética a afecciones asociadas a la osteoartritis
US20120115137A1 (en) * 2010-08-31 2012-05-10 Kornman Kenneth S Methods of Predicting Osteoarthritis
US10221456B2 (en) * 2012-08-06 2019-03-05 Merck Patent Gmbh Genetic markers for predicting responsiveness to FPG-18 compound
CN104755629A (zh) * 2012-08-06 2015-07-01 默克专利有限公司 软骨疾病的预后生物标记
CA3011363A1 (en) 2016-01-12 2017-07-20 Interleukin Genetics, Inc. Methods for predicting response to treatment
US10329620B2 (en) 2017-01-12 2019-06-25 Cardioforecast Ltd. Methods and kits for treating cardiovascular disease
HUE058848T2 (hu) 2017-09-29 2022-09-28 Merck Patent Gmbh FGF-18 vegyületre vonatkozó válaszkészség elõrejelzésére szolgáló gyulladásos biomarkerek
SI3687558T1 (sl) 2017-09-29 2022-08-31 Merck Patent Gmbh Presnovni biooznačevalci za napovedovanje odzivnosti na spojino FGF-18
EP3850113B1 (en) * 2018-09-10 2024-04-03 Merck Patent GmbH Markers useful in enrichment strategies for the treatment of osteoarthritis
US12370240B2 (en) 2018-11-28 2025-07-29 Genascence Corporation Methods and compositions for treating osteoarthritis
CA3142662A1 (en) 2019-06-06 2020-12-10 Sitokine Limited Compositions and methods for treating lung, colorectal and breast cancer
US20220265773A1 (en) * 2019-08-02 2022-08-25 New York University Methods and compositions for treating arthritis
WO2021028469A1 (en) 2019-08-12 2021-02-18 Sitokine Limited Compositions and methods for treating cytokine release syndrome and neurotoxicity
WO2021205013A1 (en) 2020-04-09 2021-10-14 Sitokine Limited Compositions and methods for treating covid-19

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GB8311018D0 (en) 1983-04-22 1983-05-25 Amersham Int Plc Detecting mutations in dna
US4998617A (en) * 1986-09-15 1991-03-12 Laura Lupton Inc Facial cosmetic liquid make up kit
US4968607A (en) * 1987-11-25 1990-11-06 Immunex Corporation Interleukin-1 receptors
US5459039A (en) 1989-05-12 1995-10-17 Duke University Methods for mapping genetic mutations
FR2650840B1 (fr) 1989-08-11 1991-11-29 Bertin & Cie Procede rapide de detection et/ou d'identification d'une seule base sur une sequence d'acide nucleique, et ses applications
US6004744A (en) 1991-03-05 1999-12-21 Molecular Tool, Inc. Method for determining nucleotide identity through extension of immobilized primer
DE69433811T2 (de) 1993-01-07 2005-06-23 Sequenom, Inc., San Diego Dns - sequenzierung durch massenspektronomie
US5593826A (en) 1993-03-22 1997-01-14 Perkin-Elmer Corporation, Applied Biosystems, Inc. Enzymatic ligation of 3'amino-substituted oligonucleotides
US5686246A (en) * 1995-08-03 1997-11-11 Kornman; Kenneth S. Detecting genetic predisposition to periodontal disease
US5942390A (en) 1996-01-12 1999-08-24 Cedars-Sinai Medical Center Method of diagnosing predisposition for ulcerative colitis in Jewish population by detection of interleukin-1 receptor antagonist polymorphism
US5698399A (en) * 1996-04-05 1997-12-16 Duff; Gordon W. Detecting genetic predisposition for osteoporosis
GB9621129D0 (en) * 1996-10-10 1996-11-27 Duff Gordon W Detecting genetic predisposition to sight-threatening diabetic retinopathy
GB9706359D0 (en) * 1997-03-27 1997-05-14 Gemini International Holdings Polymorphisms of an il-1 receptor antagonist gene
GB9711040D0 (en) * 1997-05-29 1997-07-23 Duff Gordon W Prediction of inflammatory disease
WO2003064600A2 (en) * 2002-01-25 2003-08-07 Interleukin Genetics, Inc. The il-1 gene cluster and associated inflammatory polymorphisms and haplotypes
EP2186913B1 (en) * 2003-11-26 2016-02-10 Celera Corporation Genetic polymorphisms associated with cardiovascular disorders and drug response, methods of detection and uses thereof
CA2631675A1 (en) * 2005-11-30 2007-06-21 The University Of North Carolina At Chapel Hill Identification of genetic polymorphic variants associated with somatosensory disorders and methods of using the same
ES2708826T3 (es) * 2008-05-02 2019-04-11 Orig3N Inc Detección de la predisposición genética a afecciones asociadas a la osteoartritis
US9037472B2 (en) 2012-04-20 2015-05-19 Nuance Communications, Inc. Method and system for facilitating communications for a user transaction

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