JP2010510804A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2010510804A5 JP2010510804A5 JP2009538856A JP2009538856A JP2010510804A5 JP 2010510804 A5 JP2010510804 A5 JP 2010510804A5 JP 2009538856 A JP2009538856 A JP 2009538856A JP 2009538856 A JP2009538856 A JP 2009538856A JP 2010510804 A5 JP2010510804 A5 JP 2010510804A5
- Authority
- JP
- Japan
- Prior art keywords
- diabetes
- type
- allele
- individual
- marker
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 208000001072 type 2 diabetes mellitus Diseases 0.000 claims 24
- 239000003550 marker Substances 0.000 claims 23
- 238000000034 method Methods 0.000 claims 19
- 108700028369 Alleles Proteins 0.000 claims 18
- 102000054766 genetic haplotypes Human genes 0.000 claims 7
- 239000003814 drug Substances 0.000 claims 5
- 108020004707 nucleic acids Proteins 0.000 claims 5
- 150000007523 nucleic acids Chemical class 0.000 claims 5
- 102000039446 nucleic acids Human genes 0.000 claims 5
- 239000000523 sample Substances 0.000 claims 5
- 239000013068 control sample Substances 0.000 claims 3
- 229940124597 therapeutic agent Drugs 0.000 claims 3
- 101100099162 Homo sapiens TCF7L2 gene Proteins 0.000 claims 2
- 206010012601 diabetes mellitus Diseases 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 230000002068 genetic effect Effects 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 230000004044 response Effects 0.000 claims 2
- 238000012216 screening Methods 0.000 claims 2
- 108020005187 Oligonucleotide Probes Proteins 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000002751 oligonucleotide probe Substances 0.000 claims 1
- 102220002834 rs11196205 Human genes 0.000 claims 1
- 102210041822 rs12243326 Human genes 0.000 claims 1
- 102220002833 rs12255372 Human genes 0.000 claims 1
- 102210007451 rs4506565 Human genes 0.000 claims 1
- 102210056174 rs7901695 Human genes 0.000 claims 1
- 102210030976 rs7903146 Human genes 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IS8572 | 2006-11-30 | ||
| IS8630 | 2007-04-04 | ||
| PCT/IS2007/000020 WO2008065682A2 (en) | 2006-11-30 | 2007-11-30 | Genetic susceptibility variants of type 2 diabetes mellitus |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013264999A Division JP2014097060A (ja) | 2006-11-30 | 2013-12-24 | ２型糖尿病の遺伝的感受性変異体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010510804A JP2010510804A (ja) | 2010-04-08 |
| JP2010510804A5 true JP2010510804A5 (enExample) | 2011-01-27 |
Family
ID=39102918
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009538856A Pending JP2010510804A (ja) | 2006-11-30 | 2007-11-30 | ２型糖尿病の遺伝的感受性変異体 |
| JP2013264999A Pending JP2014097060A (ja) | 2006-11-30 | 2013-12-24 | ２型糖尿病の遺伝的感受性変異体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013264999A Pending JP2014097060A (ja) | 2006-11-30 | 2013-12-24 | ２型糖尿病の遺伝的感受性変異体 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20100086921A1 (enExample) |
| EP (1) | EP2099937A2 (enExample) |
| JP (2) | JP2010510804A (enExample) |
| KR (1) | KR20090087486A (enExample) |
| AU (1) | AU2007326838B9 (enExample) |
| CA (1) | CA2683909A1 (enExample) |
| SG (1) | SG177148A1 (enExample) |
| WO (1) | WO2008065682A2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008065544A2 (en) * | 2006-09-11 | 2008-06-05 | Mcgill University | Genetic predictors of risk for type 2 diabetes mellitus |
| EP2451975A4 (en) * | 2009-05-08 | 2013-08-14 | Decode Genetics Ehf | GENETIC VARIANTS CONTRIBUTING TO A RISK OF PROSTATE CANCER |
| US8796182B2 (en) | 2009-07-10 | 2014-08-05 | Decode Genetics Ehf. | Genetic markers associated with risk of diabetes mellitus |
| JP5954724B2 (ja) * | 2011-07-25 | 2016-07-20 | 国立研究開発法人理化学研究所 | 第６染色体短腕２２領域または第９染色体長腕２１領域の一塩基多型に基づく肥満の検査方法 |
| CN105188692A (zh) * | 2013-03-29 | 2015-12-23 | 国立大学法人熊本大学 | 2型糖尿病治疗剂 |
| KR101459057B1 (ko) * | 2014-02-27 | 2014-11-12 | 서울대학교병원 (분사무소) | 임신성 당뇨병 이후 제2형 당뇨병 발병 예측 방법 |
| CN110218781B (zh) * | 2019-04-23 | 2023-03-31 | 河北医科大学 | 21个微单倍型位点的复合扩增体系、下一代测序分型试剂盒及分型方法 |
| WO2022203533A1 (ru) * | 2021-03-25 | 2022-09-29 | Владимир Валерьевич ВОЛОБУЕВ | Способ оценки предрасположенности к различным формам сахарного диабета 2го типа |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4376110A (en) * | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| JPS60501339A (ja) * | 1983-01-10 | 1985-08-22 | ジエン−プロ−ブ インコ−ポレィテッド | 生物を検出、同定又は定量する方法およびキット |
| US5288611A (en) * | 1983-01-10 | 1994-02-22 | Gen-Probe Incorporated | Method for detecting, identifying, and quantitating organisms and viruses |
| US5223409A (en) * | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5143854A (en) * | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| US5424186A (en) * | 1989-06-07 | 1995-06-13 | Affymax Technologies N.V. | Very large scale immobilized polymer synthesis |
| US5288644A (en) * | 1990-04-04 | 1994-02-22 | The Rockefeller University | Instrument and method for the sequencing of genome |
| US5384261A (en) * | 1991-11-22 | 1995-01-24 | Affymax Technologies N.V. | Very large scale immobilized polymer synthesis using mechanically directed flow paths |
| US5858659A (en) * | 1995-11-29 | 1999-01-12 | Affymetrix, Inc. | Polymorphism detection |
| US5837832A (en) * | 1993-06-25 | 1998-11-17 | Affymetrix, Inc. | Arrays of nucleic acid probes on biological chips |
| EP1080209A2 (en) * | 1998-10-21 | 2001-03-07 | Arch Development Corporation | Methods of treatment of type 2 diabetes |
| US20030092019A1 (en) * | 2001-01-09 | 2003-05-15 | Millennium Pharmaceuticals, Inc. | Methods and compositions for diagnosing and treating neuropsychiatric disorders such as schizophrenia |
| JP2006506988A (ja) * | 2002-11-01 | 2006-03-02 | デコード ジェネティクス イーエッチエフ． | 染色体５ｑ３５に位置したヒトＩＩ型糖尿病遺伝子−ＳＬＩＴ−３ |
| US20050196784A1 (en) * | 2002-11-01 | 2005-09-08 | Decode Genetics Ehf. | Human Type II diabetes gene - Kv channel-interacting protein (KChIP1) located on chromosome 5 |
| JP2008506379A (ja) * | 2004-07-16 | 2008-03-06 | オイ ユリラブ アェルテーデー | ２型糖尿病の危険性の検出及び治療のための方法 |
| US20070048751A1 (en) * | 2005-02-15 | 2007-03-01 | Jae-Heup Kim | Method of diagnosing type II diabetes mellitus using multilocus marker, polynucleotide including marker associated with type II diabetes mellitus, and microarray and diagnostic kit including the polynucleotide |
| JP2008538177A (ja) * | 2005-03-25 | 2008-10-16 | ノバルティス アクチエンゲゼルシャフト | ２型糖尿病の遺伝薬理学的診断のためのバイオマーカー |
| JP2006296270A (ja) * | 2005-04-19 | 2006-11-02 | Univ Of Tokyo | Ｐｒｋａａ２遺伝子多型による２型糖尿病発症素因の検出方法 |
| KR101374304B1 (ko) * | 2005-06-20 | 2014-03-14 | 디코드 제네틱스 이에이치에프 | 타입 2 당뇨병의 위험에 대한 진단 마커인 ｔｃｆ7ｌ2유전자의 유전적 변이체 |
-
2007
- 2007-11-30 US US12/442,233 patent/US20100086921A1/en not_active Abandoned
- 2007-11-30 SG SG2011088325A patent/SG177148A1/en unknown
- 2007-11-30 AU AU2007326838A patent/AU2007326838B9/en not_active Ceased
- 2007-11-30 WO PCT/IS2007/000020 patent/WO2008065682A2/en not_active Ceased
- 2007-11-30 JP JP2009538856A patent/JP2010510804A/ja active Pending
- 2007-11-30 EP EP07827612A patent/EP2099937A2/en not_active Withdrawn
- 2007-11-30 KR KR1020097013458A patent/KR20090087486A/ko not_active Ceased
- 2007-11-30 CA CA002683909A patent/CA2683909A1/en not_active Abandoned
-
2013
- 2013-12-24 JP JP2013264999A patent/JP2014097060A/ja active Pending