AU2007326838B9 - Genetic susceptibility variants of Type 2 diabetes mellitus - Google Patents

Genetic susceptibility variants of Type 2 diabetes mellitus Download PDF

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Publication number
AU2007326838B9
AU2007326838B9 AU2007326838A AU2007326838A AU2007326838B9 AU 2007326838 B9 AU2007326838 B9 AU 2007326838B9 AU 2007326838 A AU2007326838 A AU 2007326838A AU 2007326838 A AU2007326838 A AU 2007326838A AU 2007326838 B9 AU2007326838 B9 AU 2007326838B9
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Prior art keywords
seq
diabetes
markers
allele
type
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Ceased
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AU2007326838A
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AU2007326838B2 (en
AU2007326838A1 (en
Inventor
Valgerdur Steinthorsdottir
Gudmar Thorleifsson
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Decode Genetics ehf
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Decode Genetics ehf
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Publication of AU2007326838B9 publication Critical patent/AU2007326838B9/en
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/136Screening for pharmacological compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/172Haplotypes

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
AU2007326838A 2006-11-30 2007-11-30 Genetic susceptibility variants of Type 2 diabetes mellitus Ceased AU2007326838B9 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IS8572 2006-11-30
IS8572 2006-11-30
IS8630 2007-04-04
IS8630 2007-04-04
PCT/IS2007/000020 WO2008065682A2 (en) 2006-11-30 2007-11-30 Genetic susceptibility variants of type 2 diabetes mellitus

Publications (3)

Publication Number Publication Date
AU2007326838A1 AU2007326838A1 (en) 2008-06-05
AU2007326838B2 AU2007326838B2 (en) 2014-01-30
AU2007326838B9 true AU2007326838B9 (en) 2014-02-13

Family

ID=39102918

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2007326838A Ceased AU2007326838B9 (en) 2006-11-30 2007-11-30 Genetic susceptibility variants of Type 2 diabetes mellitus

Country Status (8)

Country Link
US (1) US20100086921A1 (enExample)
EP (1) EP2099937A2 (enExample)
JP (2) JP2010510804A (enExample)
KR (1) KR20090087486A (enExample)
AU (1) AU2007326838B9 (enExample)
CA (1) CA2683909A1 (enExample)
SG (1) SG177148A1 (enExample)
WO (1) WO2008065682A2 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008065544A2 (en) * 2006-09-11 2008-06-05 Mcgill University Genetic predictors of risk for type 2 diabetes mellitus
EP2451975A4 (en) * 2009-05-08 2013-08-14 Decode Genetics Ehf GENETIC VARIANTS CONTRIBUTING TO A RISK OF PROSTATE CANCER
US8796182B2 (en) 2009-07-10 2014-08-05 Decode Genetics Ehf. Genetic markers associated with risk of diabetes mellitus
JP5954724B2 (ja) * 2011-07-25 2016-07-20 国立研究開発法人理化学研究所 第6染色体短腕22領域または第9染色体長腕21領域の一塩基多型に基づく肥満の検査方法
CN105188692A (zh) * 2013-03-29 2015-12-23 国立大学法人熊本大学 2型糖尿病治疗剂
KR101459057B1 (ko) * 2014-02-27 2014-11-12 서울대학교병원 (분사무소) 임신성 당뇨병 이후 제2형 당뇨병 발병 예측 방법
CN110218781B (zh) * 2019-04-23 2023-03-31 河北医科大学 21个微单倍型位点的复合扩增体系、下一代测序分型试剂盒及分型方法
WO2022203533A1 (ru) * 2021-03-25 2022-09-29 Владимир Валерьевич ВОЛОБУЕВ Способ оценки предрасположенности к различным формам сахарного диабета 2го типа

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US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
JPS60501339A (ja) * 1983-01-10 1985-08-22 ジエン−プロ−ブ インコ−ポレィテッド 生物を検出、同定又は定量する方法およびキット
US5288611A (en) * 1983-01-10 1994-02-22 Gen-Probe Incorporated Method for detecting, identifying, and quantitating organisms and viruses
US5223409A (en) * 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US5143854A (en) * 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5424186A (en) * 1989-06-07 1995-06-13 Affymax Technologies N.V. Very large scale immobilized polymer synthesis
US5288644A (en) * 1990-04-04 1994-02-22 The Rockefeller University Instrument and method for the sequencing of genome
US5384261A (en) * 1991-11-22 1995-01-24 Affymax Technologies N.V. Very large scale immobilized polymer synthesis using mechanically directed flow paths
US5858659A (en) * 1995-11-29 1999-01-12 Affymetrix, Inc. Polymorphism detection
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EP1080209A2 (en) * 1998-10-21 2001-03-07 Arch Development Corporation Methods of treatment of type 2 diabetes
US20030092019A1 (en) * 2001-01-09 2003-05-15 Millennium Pharmaceuticals, Inc. Methods and compositions for diagnosing and treating neuropsychiatric disorders such as schizophrenia
JP2006506988A (ja) * 2002-11-01 2006-03-02 デコード ジェネティクス イーエッチエフ. 染色体5q35に位置したヒトII型糖尿病遺伝子−SLIT−3
US20050196784A1 (en) * 2002-11-01 2005-09-08 Decode Genetics Ehf. Human Type II diabetes gene - Kv channel-interacting protein (KChIP1) located on chromosome 5
JP2008506379A (ja) * 2004-07-16 2008-03-06 オイ ユリラブ アェルテーデー 2型糖尿病の危険性の検出及び治療のための方法
US20070048751A1 (en) * 2005-02-15 2007-03-01 Jae-Heup Kim Method of diagnosing type II diabetes mellitus using multilocus marker, polynucleotide including marker associated with type II diabetes mellitus, and microarray and diagnostic kit including the polynucleotide
JP2008538177A (ja) * 2005-03-25 2008-10-16 ノバルティス アクチエンゲゼルシャフト 2型糖尿病の遺伝薬理学的診断のためのバイオマーカー
JP2006296270A (ja) * 2005-04-19 2006-11-02 Univ Of Tokyo Prkaa2遺伝子多型による2型糖尿病発症素因の検出方法
KR101374304B1 (ko) * 2005-06-20 2014-03-14 디코드 제네틱스 이에이치에프 타입 2 당뇨병의 위험에 대한 진단 마커인 tcf7l2유전자의 유전적 변이체

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MATSUZAKI, H. et al., Nature Methods, 2004, vol. 1, no. 2, pp109-111 *
NCBI Probe Accession no. Pr003269110 retrieved on 6 February 2013 from internet URL http://www.ncbi.nlm.nih.gov/probe?term=rs9460517 *

Also Published As

Publication number Publication date
EP2099937A2 (en) 2009-09-16
US20100086921A1 (en) 2010-04-08
WO2008065682A3 (en) 2008-10-16
AU2007326838B2 (en) 2014-01-30
JP2014097060A (ja) 2014-05-29
WO2008065682A2 (en) 2008-06-05
AU2007326838A1 (en) 2008-06-05
CA2683909A1 (en) 2008-06-05
SG177148A1 (en) 2012-01-30
KR20090087486A (ko) 2009-08-17
JP2010510804A (ja) 2010-04-08

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