JP2010527603A5 - - Google Patents

Download PDF

Info

Publication number
JP2010527603A5
JP2010527603A5 JP2010508970A JP2010508970A JP2010527603A5 JP 2010527603 A5 JP2010527603 A5 JP 2010527603A5 JP 2010508970 A JP2010508970 A JP 2010508970A JP 2010508970 A JP2010508970 A JP 2010508970A JP 2010527603 A5 JP2010527603 A5 JP 2010527603A5
Authority
JP
Japan
Prior art keywords
breast cancer
individual
allele
seq
marker
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2010508970A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010527603A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IS2008/000012 external-priority patent/WO2008146309A2/en
Publication of JP2010527603A publication Critical patent/JP2010527603A/ja
Publication of JP2010527603A5 publication Critical patent/JP2010527603A5/ja
Pending legal-status Critical Current

Links

JP2010508970A 2007-05-25 2008-05-21 乳癌のリスクアセスメント、診断、予後診断および治療における使用のためのマーカーとしてのＣＨＲ５ｐ１２および１０ｑ２６上の遺伝的変異 Pending JP2010527603A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IS8647 2007-05-25
IS8700 2007-12-21
PCT/IS2008/000012 WO2008146309A2 (en) 2007-05-25 2008-05-21 Genetic variants on chr 5pl2 and 10q26 as markers for use in breast cancer risk assessment, diagnosis, prognosis and treatment

Publications (2)

Publication Number Publication Date
JP2010527603A JP2010527603A (ja) 2010-08-19
JP2010527603A5 true JP2010527603A5 (enExample) 2011-07-07

Family

ID=39661451

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010508970A Pending JP2010527603A (ja) 2007-05-25 2008-05-21 乳癌のリスクアセスメント、診断、予後診断および治療における使用のためのマーカーとしてのＣＨＲ５ｐ１２および１０ｑ２６上の遺伝的変異

Country Status (12)

Country Link
US (2) US8580501B2 (enExample)
EP (2) EP2535425A1 (enExample)
JP (1) JP2010527603A (enExample)
KR (1) KR20100017865A (enExample)
CN (1) CN101772578A (enExample)
AU (1) AU2008256219B2 (enExample)
CA (1) CA2688312A1 (enExample)
EA (1) EA018444B1 (enExample)
IL (1) IL202292A0 (enExample)
MX (1) MX2009012722A (enExample)
NZ (1) NZ581858A (enExample)
WO (1) WO2008146309A2 (enExample)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2468901T3 (en) 2005-11-29 2017-07-17 Cambridge Entpr Ltd Markers for breast cancer
JP2010527603A (ja) * 2007-05-25 2010-08-19 ディコーデ ジェネテクス イーエイチエフ 乳癌のリスクアセスメント、診断、予後診断および治療における使用のためのマーカーとしてのＣＨＲ５ｐ１２および１０ｑ２６上の遺伝的変異
EP2313525A2 (en) 2008-07-07 2011-04-27 Decode Genetics EHF Genetic variants for breast cancer risk assessment
GB2466025A (en) * 2008-12-08 2010-06-09 Univ Francois Rabelais De Tour C3/ITGAM polymorphisms and cancer prognosis
EP2438193B1 (en) * 2009-06-01 2015-07-22 Genetic Technologies Limited Methods for breast cancer risk assessment
WO2011006214A1 (en) * 2009-07-16 2011-01-20 Peter Maccallum Cancer Institute Method of detecting radiation exposure and adverse toxicity thereto
US20110151457A1 (en) * 2009-12-22 2011-06-23 Elitech Holding B.V. Hypertheromostable endonuclease iv substrate probe
WO2011095999A1 (en) * 2010-02-05 2011-08-11 Decode Genetics Ehf Genetic variants for predicting risk of breast cancer
US20140229495A1 (en) * 2011-01-19 2014-08-14 Koninklijke Philips N.V. Method for processing genomic data
WO2012172575A1 (en) * 2011-06-16 2012-12-20 Decode Genetics Ehf Genetic variants for predicting risk of breast cancer
US11261494B2 (en) 2012-06-21 2022-03-01 The Chinese University Of Hong Kong Method of measuring a fractional concentration of tumor DNA
WO2014160876A2 (en) * 2013-03-27 2014-10-02 Memorial Sloan-Kettering Cancer Center Brca2-specific modifier locus related to breast cancer risk
KR101748867B1 (ko) * 2013-04-19 2017-06-20 주식회사 젠큐릭스 조기 유방암 예후 예측 진단용 자동화 시스템
WO2015035415A1 (en) 2013-09-09 2015-03-12 Nantomics, Llc Method of detecting suceptibility to breast cancer through mutations in the fgfr3 and tp53 genes
CN103966310A (zh) * 2014-01-27 2014-08-06 广州市体育科学研究所 乳腺癌易感基因快速检测试剂盒及检测方法
CN104232774A (zh) * 2014-09-17 2014-12-24 湖北维达健基因技术有限公司 用于检测乳腺癌易感基因snp的引物、荧光探针及应用
CN107002138B (zh) 2014-09-30 2022-06-14 基因技术有限公司 用于评估发展乳腺癌风险的方法
KR20170099939A (ko) * 2014-12-16 2017-09-01 가반 인스티튜트 오브 메디컬 리서치 시퀀싱 컨트롤
PT3256605T (pt) 2015-02-10 2022-03-17 Univ Hong Kong Chinese Deteção de mutações para rastreio de cancro e análise fetal
CN106295241A (zh) * 2015-06-25 2017-01-04 杭州圣庭生物技术有限公司 基于brca1和brca2突变的乳腺癌患病风险评估算法
US10453556B2 (en) 2015-07-23 2019-10-22 The Chinese University Of Hong Kong Analysis of fragmentation patterns of cell-free DNA
CN105586427B (zh) * 2016-03-10 2020-06-19 厦门艾德生物医药科技股份有限公司 检测人类brca1和brca2基因突变的引物、试剂盒及方法
CN107723350A (zh) * 2016-08-12 2018-02-23 嘉兴允英医学检验有限公司 一种遗传性乳腺癌突变基因高通量筛查方法
TWI873615B (zh) 2017-01-25 2025-02-21 香港中文大學 使用核酸片段之診斷應用
EP3658684B1 (en) 2017-07-26 2023-08-30 The Chinese University Of Hong Kong Enhancement of cancer screening using cell-free viral nucleic acids
CN107254545B (zh) * 2017-08-16 2020-09-15 复旦大学附属华山医院北院 一种与乳腺癌化疗毒性相关的snp标志物及其应用
CN107254546B (zh) * 2017-08-16 2020-11-03 复旦大学附属华山医院 一种与乳腺癌新辅助化疗疗效相关的snp标志物及其应用
CN107729241B (zh) * 2017-10-12 2020-11-03 中国矿业大学 一种基于变异体分组的软件变异测试数据进化生成方法
KR101985864B1 (ko) * 2017-12-28 2019-06-05 주식회사 엔젠바이오 유방암 및 난소암 등 암 진단용 조성물 및 이의 용도
CN109913550A (zh) * 2019-03-21 2019-06-21 吉林省银丰生物工程技术有限公司 乳腺癌新辅助化疗效果预测基因试剂盒
RU2702755C1 (ru) * 2019-06-24 2019-10-11 Федеральное государственное бюджетное научное учреждение "Федеральный исследовательский центр фундаментальной и трансляционной медицины" (ФИЦ ФТМ) Способ молекулярно-генетической диагностики наследственных форм рака молочной железы
CN110358834B (zh) * 2019-07-12 2023-05-16 深圳大学 一种lncRNA的应用以及试剂盒和药物
CN112837749B (zh) * 2021-02-01 2021-11-26 北京百奥纳芯生物科技有限公司 一种癌症筛查用基因芯片探针的优选方法

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
GB8810400D0 (en) 1988-05-03 1988-06-08 Southern E Analysing polynucleotide sequences
US5700637A (en) 1988-05-03 1997-12-23 Isis Innovation Limited Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays
US6054270A (en) 1988-05-03 2000-04-25 Oxford Gene Technology Limited Analying polynucleotide sequences
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
ATE151110T1 (de) 1988-09-02 1997-04-15 Protein Eng Corp Herstellung und auswahl von rekombinantproteinen mit verschiedenen bindestellen
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5744101A (en) 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US5288644A (en) 1990-04-04 1994-02-22 The Rockefeller University Instrument and method for the sequencing of genome
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
WO1992020791A1 (en) 1990-07-10 1992-11-26 Cambridge Antibody Technology Limited Methods for producing members of specific binding pairs
EP0564531B1 (en) 1990-12-03 1998-03-25 Genentech, Inc. Enrichment method for variant proteins with altered binding properties
WO1992010092A1 (en) 1990-12-06 1992-06-25 Affymax Technologies N.V. Very large scale immobilized polymer synthesis
ATE363532T1 (de) 1991-03-01 2007-06-15 Dyax Corp Verfahren zur herstellung bindender miniproteine
DK1471142T3 (da) 1991-04-10 2009-03-09 Scripps Research Inst Heterodimere receptor-biblioteker under anvendelse af fagemider
DE4122599C2 (de) 1991-07-08 1993-11-11 Deutsches Krebsforsch Phagemid zum Screenen von Antikörpern
JP2001507921A (ja) 1992-04-27 2001-06-19 トラスティーズ オブ ダートマス カレッジ 生物学的液体中の遺伝子配列の検出
US6287850B1 (en) 1995-06-07 2001-09-11 Affymetrix, Inc. Bioarray chip reaction apparatus and its manufacture
EP0695941B1 (en) 1994-06-08 2002-07-31 Affymetrix, Inc. Method and apparatus for packaging a chip
US6300063B1 (en) 1995-11-29 2001-10-09 Affymetrix, Inc. Polymorphism detection
JP4468488B2 (ja) 1996-05-29 2010-05-26 コーネル・リサーチ・ファンデーション・インコーポレイテッド 組み合せたリガーゼ検出およびポリメラーゼ連鎖反応を用いる核酸配列相違の検出
US6429027B1 (en) 1998-12-28 2002-08-06 Illumina, Inc. Composite arrays utilizing microspheres
IL163645A0 (en) * 2002-02-21 2005-12-18 Idgene Pharmaceuticals Ltd Association of snps in the comt locus and neighboring loci with schizophrenia, bipolar disorder, breast cancer and colorectal cancer
EP1585433A4 (en) * 2002-09-25 2008-01-23 Ge Healthcare Sv Corp DETECTION METHODS
DE60326748D1 (de) * 2002-11-25 2009-04-30 Sequenom Inc Verfahren zur identifizierung des brustkrebsrisikos
KR101138862B1 (ko) * 2005-02-14 2012-05-14 삼성전자주식회사 단일염기 다형을 포함하는 유방암과 관련된 폴리뉴클레오티드, 그를 포함하는 마이크로어레이 및 진단 키트 및 그를이용한 유방암 진단 방법
KR101206028B1 (ko) * 2005-03-05 2012-11-28 삼성전자주식회사 유방암 특이적 다형성 서열을 이용한 유방암의 진단방법,유방암 특이적인 폴리뉴클레오티드 및 상기 폴리뉴클레오티드가 고정되어 있는 마이크로어레이
US7858303B2 (en) * 2005-03-14 2010-12-28 Wisconsin Alumni Research Foundation Method of analyzing breast cancer susceptibility and resistance
EP1888772A1 (en) * 2005-05-18 2008-02-20 Decode Genetics EHF. Variants at chr8q24.21 confer risk of cancer
US20070092900A1 (en) * 2005-10-26 2007-04-26 Stacey Simon N Methods for diagnosing and characterizing breast cancer and susceptibility to breast cancer
JP2010527603A (ja) * 2007-05-25 2010-08-19 ディコーデ ジェネテクス イーエイチエフ 乳癌のリスクアセスメント、診断、予後診断および治療における使用のためのマーカーとしてのＣＨＲ５ｐ１２および１０ｑ２６上の遺伝的変異

Similar Documents

Publication Publication Date Title
JP2010527603A5 (enExample)
JP2010507388A5 (enExample)
JP2011530306A5 (enExample)
TWI719339B (zh) 與癌症有關之基因或分子變異之檢測
JP2010520745A5 (enExample)
JP2010522555A5 (enExample)
JP6820838B2 (ja) 乳癌発症リスクを評価する方法
JP2012525147A5 (enExample)
JP2010533477A5 (enExample)
CA2511042A1 (en) Association of single nucleotide polymorphisms in ppar.gamma. with osteoporosis
EP3332031B1 (en) Snp rs12603226 as a predictive marker for nafld
CN103998624A (zh) 具有多个靶区域特异性和具有分为三部分特征的探针
CN105624296A (zh) 基于arms荧光pcr法检测基因多态性的通用型荧光发夹引物
JP2010510804A5 (enExample)
US20220162710A1 (en) Composition for diagnosis or prognosis prediction of glioma, and method for providing information related thereto
CN106030307A (zh) 用于确定基因组完整性和/或通过确定性限制位点全基因组扩增获得的dna序列的文库质量的方法和试剂盒
JP5807894B2 (ja) 一塩基多型に基づく前立腺癌の検査方法
CN111172248A (zh) 一种基于片段分析技术验证拷贝数变异的通用试剂盒
US20160053333A1 (en) Novel Haplotype Tagging Single Nucleotide Polymorphisms and Use of Same to Predict Childhood Lymphoblastic Leukemia
JP5866669B2 (ja) 乳がん発症感受性の判定方法
CN102154452A (zh) 一种鉴定顺式和反式调控作用的方法和系统
KR20110034297A (ko) 내인성 아토피 피부염 진단용 마커 및 그의 용도
KR102304998B1 (ko) 우리흑돈의 전신 흑모색 식별용 snp 마커 및 이를 이용한 전신 흑모색 식별 방법
JP5656159B2 (ja) インターフェロン療法の効果予測用マーカー
JP4825956B2 (ja) 気道粘膜炎症性疾患の罹患リスクの判定