JP2010527603A - 乳癌のリスクアセスメント、診断、予後診断および治療における使用のためのマーカーとしてのＣＨＲ５ｐ１２および１０ｑ２６上の遺伝的変異 - Google Patents

乳癌のリスクアセスメント、診断、予後診断および治療における使用のためのマーカーとしてのＣＨＲ５ｐ１２および１０ｑ２６上の遺伝的変異 Download PDF

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JP2010527603A
JP2010527603A JP2010508970A JP2010508970A JP2010527603A JP 2010527603 A JP2010527603 A JP 2010527603A JP 2010508970 A JP2010508970 A JP 2010508970A JP 2010508970 A JP2010508970 A JP 2010508970A JP 2010527603 A JP2010527603 A JP 2010527603A
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breast cancer
allele
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risk
markers
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サイモン ステイシー
パトリック スレム
アンドレイ マノレスク
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ディコーデ ジェネテクス イーエイチエフ
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    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
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  • Chemical & Material Sciences (AREA)
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  • Spectroscopy & Molecular Physics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2010508970A 2007-05-25 2008-05-21 乳癌のリスクアセスメント、診断、予後診断および治療における使用のためのマーカーとしてのＣＨＲ５ｐ１２および１０ｑ２６上の遺伝的変異 Pending JP2010527603A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IS8647 2007-05-25
IS8700 2007-12-21
PCT/IS2008/000012 WO2008146309A2 (en) 2007-05-25 2008-05-21 Genetic variants on chr 5pl2 and 10q26 as markers for use in breast cancer risk assessment, diagnosis, prognosis and treatment

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JP2010527603A true JP2010527603A (ja) 2010-08-19
JP2010527603A5 JP2010527603A5 (enExample) 2011-07-07

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US (2) US8580501B2 (enExample)
EP (2) EP2535425A1 (enExample)
JP (1) JP2010527603A (enExample)
KR (1) KR20100017865A (enExample)
CN (1) CN101772578A (enExample)
AU (1) AU2008256219B2 (enExample)
CA (1) CA2688312A1 (enExample)
EA (1) EA018444B1 (enExample)
IL (1) IL202292A0 (enExample)
MX (1) MX2009012722A (enExample)
NZ (1) NZ581858A (enExample)
WO (1) WO2008146309A2 (enExample)

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CN102144036B (zh) 2008-07-07 2014-07-16 解码遗传学私营有限责任公司 用于乳腺癌风险评估的遗传变型
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KR101748867B1 (ko) * 2013-04-19 2017-06-20 주식회사 젠큐릭스 조기 유방암 예후 예측 진단용 자동화 시스템
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CN104232774A (zh) * 2014-09-17 2014-12-24 湖北维达健基因技术有限公司 用于检测乳腺癌易感基因snp的引物、荧光探针及应用
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EP4279612B1 (en) 2015-07-23 2025-07-02 The Chinese University of Hong Kong Analysis of fragmentation patterns of cell-free dna
CN105586427B (zh) * 2016-03-10 2020-06-19 厦门艾德生物医药科技股份有限公司 检测人类brca1和brca2基因突变的引物、试剂盒及方法
CN107723350A (zh) * 2016-08-12 2018-02-23 嘉兴允英医学检验有限公司 一种遗传性乳腺癌突变基因高通量筛查方法
AU2018212272B2 (en) 2017-01-25 2022-04-28 Grail, Inc. Diagnostic applications using nucleic acid fragments
CN111051536A (zh) 2017-07-26 2020-04-21 香港中文大学 利用不含细胞的病毒核酸改善癌症筛选
CN107254545B (zh) * 2017-08-16 2020-09-15 复旦大学附属华山医院北院 一种与乳腺癌化疗毒性相关的snp标志物及其应用
CN107254546B (zh) * 2017-08-16 2020-11-03 复旦大学附属华山医院 一种与乳腺癌新辅助化疗疗效相关的snp标志物及其应用
CN107729241B (zh) * 2017-10-12 2020-11-03 中国矿业大学 一种基于变异体分组的软件变异测试数据进化生成方法
KR101985864B1 (ko) * 2017-12-28 2019-06-05 주식회사 엔젠바이오 유방암 및 난소암 등 암 진단용 조성물 및 이의 용도
CN109913550A (zh) * 2019-03-21 2019-06-21 吉林省银丰生物工程技术有限公司 乳腺癌新辅助化疗效果预测基因试剂盒
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US8580501B2 (en) 2013-11-12
KR20100017865A (ko) 2010-02-16
AU2008256219B2 (en) 2014-06-05
AU2008256219A1 (en) 2008-12-04
EP2164984A2 (en) 2010-03-24
WO2008146309A2 (en) 2008-12-04
CA2688312A1 (en) 2008-12-04
EA018444B1 (ru) 2013-08-30
EP2535425A1 (en) 2012-12-19
CN101772578A (zh) 2010-07-07
US20110015081A1 (en) 2011-01-20
EA200971079A1 (ru) 2010-06-30
WO2008146309A3 (en) 2009-01-22
US20140179546A1 (en) 2014-06-26
IL202292A0 (en) 2010-06-16
MX2009012722A (es) 2009-12-11
NZ581858A (en) 2012-07-27

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