EA018444B1 - ГЕНЕТИЧЕСКИЕ ВАРИАНТЫ В Chr 5p12 И 10q26 В КАЧЕСТВЕ МАРКЕРОВ ДЛЯ ПРИМЕНЕНИЯ ПРИ ОЦЕНКЕ РИСКА, ДИАГНОСТИРОВАНИИ, ПРОГНОЗИРОВАНИИ И ЛЕЧЕНИИ РАКА ГРУДИ - Google Patents

ГЕНЕТИЧЕСКИЕ ВАРИАНТЫ В Chr 5p12 И 10q26 В КАЧЕСТВЕ МАРКЕРОВ ДЛЯ ПРИМЕНЕНИЯ ПРИ ОЦЕНКЕ РИСКА, ДИАГНОСТИРОВАНИИ, ПРОГНОЗИРОВАНИИ И ЛЕЧЕНИИ РАКА ГРУДИ Download PDF

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EA018444B1
EA018444B1 EA200971079A EA200971079A EA018444B1 EA 018444 B1 EA018444 B1 EA 018444B1 EA 200971079 A EA200971079 A EA 200971079A EA 200971079 A EA200971079 A EA 200971079A EA 018444 B1 EA018444 B1 EA 018444B1
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breast cancer
risk
markers
allele
marker
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EA200971079A
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Russian (ru)
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EA200971079A1 (ru
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Симон Стейси
Патрик Сулем
Андрей Манолеску
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Декоуд Дженетикс Ехф.
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/10Ploidy or copy number detection
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
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    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
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    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/172Haplotypes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

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  • Chemical & Material Sciences (AREA)
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  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
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  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
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  • Bioinformatics & Computational Biology (AREA)
  • Medical Informatics (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
EA200971079A 2007-05-25 2008-05-21 ГЕНЕТИЧЕСКИЕ ВАРИАНТЫ В Chr 5p12 И 10q26 В КАЧЕСТВЕ МАРКЕРОВ ДЛЯ ПРИМЕНЕНИЯ ПРИ ОЦЕНКЕ РИСКА, ДИАГНОСТИРОВАНИИ, ПРОГНОЗИРОВАНИИ И ЛЕЧЕНИИ РАКА ГРУДИ EA018444B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IS8647 2007-05-25
IS8700 2007-12-21
PCT/IS2008/000012 WO2008146309A2 (en) 2007-05-25 2008-05-21 Genetic variants on chr 5pl2 and 10q26 as markers for use in breast cancer risk assessment, diagnosis, prognosis and treatment

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EA200971079A1 EA200971079A1 (ru) 2010-06-30
EA018444B1 true EA018444B1 (ru) 2013-08-30

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US (2) US8580501B2 (enExample)
EP (2) EP2535425A1 (enExample)
JP (1) JP2010527603A (enExample)
KR (1) KR20100017865A (enExample)
CN (1) CN101772578A (enExample)
AU (1) AU2008256219B2 (enExample)
CA (1) CA2688312A1 (enExample)
EA (1) EA018444B1 (enExample)
IL (1) IL202292A0 (enExample)
MX (1) MX2009012722A (enExample)
NZ (1) NZ581858A (enExample)
WO (1) WO2008146309A2 (enExample)

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US10240209B2 (en) 2015-02-10 2019-03-26 The Chinese University Of Hong Kong Detecting mutations for cancer screening
RU2702755C1 (ru) * 2019-06-24 2019-10-11 Федеральное государственное бюджетное научное учреждение "Федеральный исследовательский центр фундаментальной и трансляционной медицины" (ФИЦ ФТМ) Способ молекулярно-генетической диагностики наследственных форм рака молочной железы
US10633713B2 (en) 2017-01-25 2020-04-28 The Chinese University Of Hong Kong Diagnostic applications using nucleic acid fragments
US11261494B2 (en) 2012-06-21 2022-03-01 The Chinese University Of Hong Kong Method of measuring a fractional concentration of tumor DNA
US12234515B2 (en) 2017-07-26 2025-02-25 The Chinese University Of Hong Kong Enhancement of cancer screening using cell-free viral nucleic acids

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CN102144036B (zh) 2008-07-07 2014-07-16 解码遗传学私营有限责任公司 用于乳腺癌风险评估的遗传变型
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CN103966310A (zh) * 2014-01-27 2014-08-06 广州市体育科学研究所 乳腺癌易感基因快速检测试剂盒及检测方法
CN104232774A (zh) * 2014-09-17 2014-12-24 湖北维达健基因技术有限公司 用于检测乳腺癌易感基因snp的引物、荧光探针及应用
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CN107250356A (zh) * 2014-12-16 2017-10-13 加文医学研究所 测序对照
CN106295241A (zh) * 2015-06-25 2017-01-04 杭州圣庭生物技术有限公司 基于brca1和brca2突变的乳腺癌患病风险评估算法
EP4279612B1 (en) 2015-07-23 2025-07-02 The Chinese University of Hong Kong Analysis of fragmentation patterns of cell-free dna
CN105586427B (zh) * 2016-03-10 2020-06-19 厦门艾德生物医药科技股份有限公司 检测人类brca1和brca2基因突变的引物、试剂盒及方法
CN107723350A (zh) * 2016-08-12 2018-02-23 嘉兴允英医学检验有限公司 一种遗传性乳腺癌突变基因高通量筛查方法
CN107254545B (zh) * 2017-08-16 2020-09-15 复旦大学附属华山医院北院 一种与乳腺癌化疗毒性相关的snp标志物及其应用
CN107254546B (zh) * 2017-08-16 2020-11-03 复旦大学附属华山医院 一种与乳腺癌新辅助化疗疗效相关的snp标志物及其应用
CN107729241B (zh) * 2017-10-12 2020-11-03 中国矿业大学 一种基于变异体分组的软件变异测试数据进化生成方法
KR101985864B1 (ko) * 2017-12-28 2019-06-05 주식회사 엔젠바이오 유방암 및 난소암 등 암 진단용 조성물 및 이의 용도
CN109913550A (zh) * 2019-03-21 2019-06-21 吉林省银丰生物工程技术有限公司 乳腺癌新辅助化疗效果预测基因试剂盒
CN110358834B (zh) * 2019-07-12 2023-05-16 深圳大学 一种lncRNA的应用以及试剂盒和药物
CN112837749B (zh) * 2021-02-01 2021-11-26 北京百奥纳芯生物科技有限公司 一种癌症筛查用基因芯片探针的优选方法

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11261494B2 (en) 2012-06-21 2022-03-01 The Chinese University Of Hong Kong Method of measuring a fractional concentration of tumor DNA
US10240209B2 (en) 2015-02-10 2019-03-26 The Chinese University Of Hong Kong Detecting mutations for cancer screening
US11168370B2 (en) 2015-02-10 2021-11-09 The Chinese University Of Hong Kong Detecting mutations for cancer screening
US10633713B2 (en) 2017-01-25 2020-04-28 The Chinese University Of Hong Kong Diagnostic applications using nucleic acid fragments
US11479825B2 (en) 2017-01-25 2022-10-25 The Chinese University Of Hong Kong Diagnostic applications using nucleic acid fragments
US12234515B2 (en) 2017-07-26 2025-02-25 The Chinese University Of Hong Kong Enhancement of cancer screening using cell-free viral nucleic acids
RU2702755C1 (ru) * 2019-06-24 2019-10-11 Федеральное государственное бюджетное научное учреждение "Федеральный исследовательский центр фундаментальной и трансляционной медицины" (ФИЦ ФТМ) Способ молекулярно-генетической диагностики наследственных форм рака молочной железы

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US8580501B2 (en) 2013-11-12
KR20100017865A (ko) 2010-02-16
AU2008256219B2 (en) 2014-06-05
JP2010527603A (ja) 2010-08-19
AU2008256219A1 (en) 2008-12-04
EP2164984A2 (en) 2010-03-24
WO2008146309A2 (en) 2008-12-04
CA2688312A1 (en) 2008-12-04
EP2535425A1 (en) 2012-12-19
CN101772578A (zh) 2010-07-07
US20110015081A1 (en) 2011-01-20
EA200971079A1 (ru) 2010-06-30
WO2008146309A3 (en) 2009-01-22
US20140179546A1 (en) 2014-06-26
IL202292A0 (en) 2010-06-16
MX2009012722A (es) 2009-12-11
NZ581858A (en) 2012-07-27

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